ARRA Investments in Diagnostic Imaging
Public Health Burden
Recent innovations in diagnostic imaging technologies have led to more accurate diagnosis of disease and injury, as well as less-invasive biopsies and treatments. A recent example is the use of image-guided interventions in the biopsy and treatment of prostate cancer, the most frequent non-dermatological cancer among U.S. males.
Technologies for image-guided interventions provide new, minimally invasive procedures and will significantly impact the treatment of disease and injury. A variety of ARRA funded grants are exploring new image-guided interventions. For example:
Comparative effectiveness studies of image-guided, robotic prostatectomy with standard invasive prostatectomy.
Development of novel technologies to improve the accuracy of prostate biopsy sampling, using MRI-guided approaches
and combined electrical impedance/ultrasound imaging approaches.
Development of a novel technology for non-invasive biopsy of bile duct cancer that uses a micro-optical imaging device at the tip of a flexible catheter.
Comparative effectiveness studies of image-guided, robotic treatments with traditional open surgery approaches for vaginal prolapse.
Other Diagnostic Imaging Technologies
A variety of ARRA funded grants are exploring the development of other new diagnostic imaging technologies that promise to have a significant impact on diagnosis and treatment of many diseases. For example:
Development of novel high-speed MR spectroscopic imaging technologies that can increase the sensitivity and specificity of breast cancer diagnosis.
Comparative effectiveness studies of novel non-invasive MR elastography approaches with standard invasive biopsies for detection and characterization of liver fibrosis.
Comparative effectiveness studies of novel MRI perfusion techniques with conventional cross sectional CT imaging approaches for diagnosis and characterization of liver tumors.
Development of novel techniques that can quantitatively assess the tradeoffs between diagnostic performance and radiation risk for combined PET/CT and SPECT/CT approaches.
Development of novel carbon “nanotubes” for tracking the migration of transplanted therapeutic stem cells using MRI.
-- Effectiveness of Robotic Compared to Standard Prostatectomy for Prostate Cancer -- SANDA, MARTIN (MD)
-- Robot-Assisted MRI-Guided Prostate Biopsy -- STOIANOVICI, DAN (MD)
-- Electrical Property Based Image-guided Prostate Biopsy -- HALTER, RYAN J. (NH)
-- Laser Endoscopy for Guided Biopsy in the Bile Duct -- SEIBEL, ERIC J (WA)
-- Comparative Efficacy of Robotic vs Open Sacrocolpopexy for Vaginal Vault Prolapse -- ANGER, JENNIFER (CA)
-- Volumetric Mapping of Breast Cancer Biomarkers using High-Speed MR Spectroscopic Imaging -- POSSE, STEFAN (NM)
-- Comparative Effectiveness of Advanced Diagnostic Imaging for Hepatic Fibrosis -- TALWALKER, JAYANT (MN)
-- Volumetric Perfusion MRI of Liver Tumors to Detect Early Response to Chemotherapy -- REEDER, SCOTT (WI)
-- Quantitative Assessment of the Benefits and Risks of Clinical PET/CT and SPECT/CT -- KUPINSKI, MATTHEW (AZ)
-- Gadonanotubes as New MRI Nanolabels for Stem Cell Tracking -- PERIN, EMERSON (TX)
Page Last Updated on June 30, 2018
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