Collaboration Details

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Title of Collaborative Activity:

Library of Integrated Network-based Cellular Signatures (LINCS)

Description of Collaborative Activity:

The Library of Integrated Network-based Cellular Signatures (LINCS) program is developing a library of data at the cellular level that describes how different types of cells respond to a variety of agents that disrupt normal cellular functions, called “perturbagens.” This library may help us better understand normal and diseased conditions in cells and how to alter them. In FY2016, the LINCS program discussed with the Food and Drug Administration (FDA) how LINCS data may be used to predict the toxicity of drugs in cardiac (heart) cells.

Type of Collaborative Activity:

Research Initiative

Year the Collaborative Activity Originated:


NIH Participating Institutes/Centers/Office of the Director:


HHS Agency Collaborators on this Activity: