Collaboration Details

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Title of Collaborative Activity:

Long-term Oxygen Treatment Trial

Description of Collaborative Activity:

The Long-term Oxygen Treatment Trial (LOTT) is a randomized controlled clinical trial to assess the efficacy of around-the-clock, supplemental oxygen therapy in subjects with chronic obstructive pulmonary disease and moderately severe hypoxemia. NHLBI administered and oversaw the study, and Medicare covered the costs of items and medical services that are generally available through that program to beneficiaries enrolled in the trial.

Type of Collaborative Activity:

Research Initiative

Year the Collaborative Activity Originated:


NIH Participating Institutes/Centers/Office of the Director:


HHS Agency Collaborators on this Activity: