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RCDC

Project Listing by Category


Back to Estimates of Funding for Various Research, Condition, and Disease Categories (RCDC) Click the column headings to sort project listings.
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CategoryFYFunding ICProject NumberSub Project #Project TitlePI NameOrg NameState / CountryAmount
Childhood Leukemia 2019 NCI 5R01CA201788-04 Probiotics for Prevention of Acute Graft-vs-Host Disease in Children with Cancer LADAS, ELENA COLUMBIA UNIVERSITY HEALTH SCIENCES NY $744,609
Childhood Leukemia 2019 NCI 1K22CA229606-01 Investigating the role of epitranscriptomic A-to-I RNA editing in T-cell acute lymphoblastic leukemia JIANG, QINGFEI UNIVERSITY OF CALIFORNIA, SAN DIEGO CA $191,213
Childhood Leukemia 2019 NIGMS 5R01GM118578-03 Genetics-guided Individualization of Thiopurine Therapy YANG, JUN ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $549,331
Childhood Leukemia 2019 NCI 5R01CA194058-04 Painted erythrocyte carriers for therapy of acute myeloid leukemia SIMBERG, DIMITRI UNIVERSITY OF COLORADO DENVER CO $341,585
Childhood Leukemia 2019 NCI 5R01CA190964-05 Role of IKAROS in the Biology and Therapy of High-Risk Precursor B-Cell Leukemia VAN ETTEN, RICHARD UNIVERSITY OF CALIFORNIA-IRVINE CA $527,781
Childhood Leukemia 2019 NCI 5R01CA201184-04 Biologic and Therapeutic Significance of miR-155 in AML MARCUCCI, GUIDO BECKMAN RESEARCH INSTITUTE/CITY OF HOPE CA $515,834
Childhood Leukemia 2019 NCI 5R01CA211044-03 Off-the-shelf engineered NK cells for the treatment of AML REZVANI, KATY UNIVERSITY OF TX MD ANDERSON CAN CTR TX $355,019
Childhood Leukemia 2019 NCI 5R01CA222590-02 Developing a novel therapeutic strategy for overcoming TKI resistance in ALL LI, SHAOGUANG UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $473,211
Childhood Leukemia 2019 NCI 5R01CA211711-03 APPLYING ERROR-CORRECTED SEQUENCING TO DETECT MINIMAL RESIDUAL IN THE AAML 1031 STUDY DRULEY, TODD WASHINGTON UNIVERSITY MO $342,009
Childhood Leukemia 2019 NCI 5R01CA212649-03 Personalized vaccine for patients with AML AVIGAN, DAVID BETH ISRAEL DEACONESS MEDICAL CENTER MA $699,542
Childhood Leukemia 2019 NCI 5R01CA204979-03 Mechanisms of inv(16) acute myeloid leukemia CASTILLA, LUCIO UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $413,998
Childhood Leukemia 2019 NCI 5R03CA223730-02 Genetic underpinnings of ethnic disparities in bone toxicities between Hispanic and non-Hispanic children treated for acute lymphoblastic leukemia YAO, SONG ROSWELL PARK CANCER INSTITUTE CORP NY $87,050
Childhood Leukemia 2019 NHLBI 5K08HL135434-03 Targeting SETBP1 in Myeloproliferative Disorders STIEGLITZ, ELLIOT UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $179,928
Childhood Leukemia 2019 NCI 5R01CA213131-03 Targeting Transcriptional Regulators for Immunotherapy of Acute Myeloid Leukemia KORTYLEWSKI, MARCIN BECKMAN RESEARCH INSTITUTE/CITY OF HOPE CA $413,286
Childhood Leukemia 2019 NCI 5R21CA209298-02 A novel genetic pathway for survival of B-lymphoblastic leukemia-initiating cells LI, SHAOGUANG UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $176,690
Childhood Leukemia 2019 NCI 5P30CA006516-54 5399 Program 4: Leukemia EBERT, BENJAMIN BRIGHAM AND WOMEN'S HOSPITAL MA $73,081
Childhood Leukemia 2019 NCI 5F30CA213878-03 Co-Evolution of the CD8+ T Cell Repertoire and AML In the Setting of Immunotherapy GEORGE, JASON RICE UNIVERSITY TX $45,640
Childhood Leukemia 2019 NCI 5R01CA211614-03 Targeting TET1 signaling to treat acute myeloid leukemia CHEN, JIANJUN BECKMAN RESEARCH INSTITUTE/CITY OF HOPE CA $443,591
Childhood Leukemia 2019 NCI 5P30CA016520-43 8007 Hematologic Malignancies Research Program STADTMAUER, EDWARD UNIVERSITY OF PENNSYLVANIA PA $74,500
Childhood Leukemia 2019 NHLBI 5R01HL130034-04 The Cebpa Enhancer in Normal Hematopoiesis and Progression to AML FRIEDMAN, ALAN JOHNS HOPKINS UNIVERSITY MD $405,000
Childhood Leukemia 2019 NCI 5R01CA215518-02 Targeting the Notch:Myc axis in leukemia/lymphoma PEAR, WARREN UNIVERSITY OF PENNSYLVANIA PA $450,421
Childhood Leukemia 2019 NCI 5R01CA142665-09 Glucocorticoids in Lymphoblastic Leukemia RELLING, MARY ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $473,354
Childhood Leukemia 2019 NCI 5R01CA163086-07 Function and targeting of a stable transcription factor complex in leukemia ROEDER, ROBERT ROCKEFELLER UNIVERSITY NY $376,098
Childhood Leukemia 2019 NCI 5R01CA142874-09 Targeting PML for Leukemia Therapy PANDOLFI, PIER PAOLO BETH ISRAEL DEACONESS MEDICAL CENTER MA $443,273
Childhood Leukemia 2019 NCI 5R01CA192924-05 CSF2 receptor mediated actions in t(8;21) leukemia ZHANG, DONG-ER UNIVERSITY OF CALIFORNIA, SAN DIEGO CA $330,714
Childhood Leukemia 2019 NCI 5R35CA197695-03 Translating genomic discoveries to improved outcomes for high risk acute leukemia MULLIGHAN, CHARLES ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $1,044,690
Childhood Leukemia 2019 NCI 5R01CA201225-04 Leukemia Specific Splice Isoforms as Neo-Antigens for T-Cell Immunotherapy ARMISTEAD, PAUL UNIV OF NORTH CAROLINA CHAPEL HILL NC $456,823
Childhood Leukemia 2019 NCI 5R01CA047148-32 Synthesis and Study of Natural and Non-natural Antiproliferative Agents MYERS, ANDREW HARVARD UNIVERSITY MA $725,971
Childhood Leukemia 2019 NCI 1UG1CA233249-01 COG NCTN Integrated Translational Science Center for Hematopoietic Malignancies in Children MESHINCHI, SOHEIL CHILDREN'S HOSP OF PHILADELPHIA PA $800,000
Childhood Leukemia 2019 NIGMS 5R01GM126363-02 Mechanistic Studies of Type II Topoisomerases and Topoisomerase-Targeted Agents OSHEROFF, NEIL VANDERBILT UNIVERSITY TN $302,225
Childhood Leukemia 2019 NCI 2P30CA021765-40 5519 Biostatistics Shared Resources Core SRIVASTAVA, DEO KUMAR ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $835,833
Childhood Leukemia 2019 NCI 2P30CA021765-40 5530 Hematological Malignancies Program MULLIGHAN, CHARLES ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $67,924
Childhood Leukemia 2019 NCI 5R01CA152108-08 Molecular and Cellular Mechanisms of Chronic Myelomonocytic Leukemia (CMML) ZHANG, JING UNIVERSITY OF WISCONSIN-MADISON WI $353,933
Childhood Leukemia 2019 NCI 2P01CA101937-15A1 5989 Project 1 - Genomics of Intermediate-Risk AML Progression and Relapse. LEY, TIMOTHY WASHINGTON UNIVERSITY MO $238,506
Childhood Leukemia 2019 NCI 2P01CA101937-15A1 5990 Project 2 - Genomics of Allogeneic Transplantation. DIPERSIO, JOHN WASHINGTON UNIVERSITY MO $238,509
Childhood Leukemia 2019 NCI 2P01CA101937-15A1 5991 Project 3 - Genomics of Secondary AML Progression. WALTER, MATTHEW WASHINGTON UNIVERSITY MO $238,507
Childhood Leukemia 2019 NCI 2P01CA101937-15A1 5992 Project 4 - Genomics of TP53-mutant AML. LINK, DANIEL WASHINGTON UNIVERSITY MO $238,505
Childhood Leukemia 2019 NCI 2P01CA101937-15A1 5993 Core D: Administration Core. LEY, TIMOTHY WASHINGTON UNIVERSITY MO $42,833
Childhood Leukemia 2019 NCI 2P01CA101937-15A1 5994 Core A - Clinical Database. WESTERVELT, PETER WASHINGTON UNIVERSITY MO $185,917
Childhood Leukemia 2019 NCI 2P01CA101937-15A1 5995 Core B - Specimen Database. PAYTON, JACQUELINE WASHINGTON UNIVERSITY MO $84,666
Childhood Leukemia 2019 NCI 2P01CA101937-15A1 5996 Core C - Sequencing and Analysis. MILLER, CHRISTOPHER WASHINGTON UNIVERSITY MO $817,313
Childhood Leukemia 2019 NCI 5R01CA151898-09 CRLF2 signaling in B-cell acute lymphoblastic leukemia WEINSTOCK, DAVID DANA-FARBER CANCER INST MA $381,181
Childhood Leukemia 2019 NHLBI 5K08HL140138-02 Investigating the Mechanisms of Cohesinopathy in Myelodysplastic Syndromes TOTHOVA, ZUZANA DANA-FARBER CANCER INST MA $171,720
Childhood Leukemia 2019 NCI 1R21CA222764-01A1 Modeling Vincristine-Induced Severe and Persistent Neuropathy DOLAN, MARY UNIVERSITY OF CHICAGO IL $211,410
Childhood Leukemia 2019 NHLBI 1R01HL144653-01 Cellular and functional impact of SAMD9L mutations on hematopoiesis and myelodysplasia KLCO, JEFFERY ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $448,750
Childhood Leukemia 2019 NCI 1R01CA234478-01 Targeted Small Molecule Inhibitors for Inv(16) Leukemia BUSHWELLER, JOHN UNIVERSITY OF VIRGINIA VA $716,817
Childhood Leukemia 2019 NCI 5K08CA222684-02 Targeting mitochondrial one carbon folate metabolism for novel T-cell acute lymphoblastic leukemia therapy PIKMAN, YANA DANA-FARBER CANCER INST MA $177,120
Childhood Leukemia 2019 NCI 5R01CA190843-05 A Label-Free, Point-of-Care Platform to Diagnose Acute Promyelocytic Leukemia SOHN, LYDIA UNIVERSITY OF CALIFORNIA BERKELEY CA $302,113
Childhood Leukemia 2019 NCI 5F30CA217006-03 Analysis of the novel phenomenon of antibody-mediated fratricide in Acute Myeloid Leukemia FATEHCHAND, KAVIN OHIO STATE UNIVERSITY OH $50,016
Childhood Leukemia 2019 NCI 5R01CA188520-05 Genome maintenance by Hdacs1,2 and their inhibition for Pre-B leukemia therapy BHASKARA, SRIVIDYA UNIVERSITY OF UTAH UT $330,612
Childhood Leukemia 2019 NCI 1R21CA234203-01 Novel Approach to CD33-Targeted Immunotherapy of Acute Myeloid Leukemia WALTER, ROLAND FRED HUTCHINSON CANCER RESEARCH CENTER WA $236,741
Childhood Leukemia 2019 NCI 5R01CA194057-05 Metabolic pathways in leukemia SCHUETZ, JOHN ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $398,287
Childhood Leukemia 2019 NCI 5R01CA207086-03 Mechanisms of KLF4 suppression in pediatric leukemia LACORAZZA, DANIEL BAYLOR COLLEGE OF MEDICINE TX $359,522
Childhood Leukemia 2019 NCI 5R01CA214965-04 The role and mechanism of FTO in leukemogenesis and drug response CHEN, JIANJUN BECKMAN RESEARCH INSTITUTE/CITY OF HOPE CA $413,529
Childhood Leukemia 2019 NCI 1R21CA223141-01A1 Translation development of a novel therapeutic antibody against drug-resistant B-cell malignancies QIN, HONG BECKMAN RESEARCH INSTITUTE/CITY OF HOPE CA $188,138
Childhood Leukemia 2019 NCI 5R01CA214888-02 Functional and Translational Epigenomics of Acute Lymphoblastic Leukemia CLEARY, MICHAEL STANFORD UNIVERSITY CA $356,412
Childhood Leukemia 2019 NCI 5P01CA013106-47 5085 Project 4: Transcriptional Coactivators and Enhancers in Human Cancer VAKOC, CHRISTOPHER COLD SPRING HARBOR LABORATORY NY $536,356
Childhood Leukemia 2019 NCI 5R35CA197628-04 Metabolic basis of B cell lineage leukemia relapse MUSCHEN, MARKUS BECKMAN RESEARCH INSTITUTE/CITY OF HOPE CA $1,003,965
Childhood Leukemia 2019 NCI 5R01CA217092-04 Mechanisms of Formation and Progression of Preleukemic Stem Cells STEIDL, ULRICH ALBERT EINSTEIN COLLEGE OF MEDICINE NY $385,453
Childhood Leukemia 2019 NCI 5K08CA222699-02 Targeting MerTK as an immunotherapeutic strategy in acute myeloid leukemia LEE SHERICK, ALISA UNIVERSITY OF COLORADO DENVER CO $175,285
Childhood Leukemia 2019 NCI 5K08CA204734-04 Determining the Role of BCOR Mutations in Myeloid Malignancies LINDSLEY, ROBERT DANA-FARBER CANCER INST MA $141,236
Childhood Leukemia 2019 NCI 1R03CA219523-01A1 Identifying and targeting epigenetic vulnerabilities in NOTCH1 driven leukemia TZATSOS, ALEXANDROS GEORGE WASHINGTON UNIVERSITY DC $79,750
Childhood Leukemia 2019 NCI 5F30CA217027-03 Investigating the role of miR-155 and the interferon response in FLT3-ITD+ AML WALLACE, JARED UNIVERSITY OF UTAH UT $50,016
Childhood Leukemia 2019 NCI 5R01CA215504-03 Instructive role of MLL fusion proteins in lineage determination and leukemogenesis THIRMAN, MICHAEL UNIVERSITY OF CHICAGO IL $576,709
Childhood Leukemia 2019 NCI 5R21CA221702-02 Directed Purinergic Signaling as Immunotherapy in Leukemia ROBSON, SIMON BETH ISRAEL DEACONESS MEDICAL CENTER MA $184,603
Childhood Leukemia 2019 NCI 5R01CA193842-05 Characterizing MSI2 in leukemia KHARAS, MICHAEL SLOAN-KETTERING INST CAN RESEARCH NY $410,846
Childhood Leukemia 2019 NCI 5R01CA225231-02 Identification of therapeutic targets for leukemia stem cells in AML-iPSC models PAPAPETROU, EIRINI ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI NY $586,205
Childhood Leukemia 2019 NCI 5K08CA201640-03 Developing differentiation therapy for the treatment of patients with acute myeloid leukemia SYKES, DAVID MASSACHUSETTS GENERAL HOSPITAL MA $169,268
Childhood Leukemia 2019 NHLBI 5K08HL136894-03 Hedgehog Signaling in the Progression of Myelodysplastic Syndromes GONDEK, LUKASZ JOHNS HOPKINS UNIVERSITY MD $171,720
Childhood Leukemia 2019 NCI 1R01CA226759-01A1 Targeting NSD1 in leukemia CIERPICKI, TOMASZ UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $484,924
Childhood Leukemia 2019 NCI 1R01CA226436-01A1 AKR1C3 Inhibitors as Chemotherapeutic Potentiators TRIPPIER, PAUL TEXAS TECH UNIVERSITY HEALTH SCIS CENTER TX $93,328
Childhood Leukemia 2019 NCI 5R01CA195642-05 Triad1 regulates myelopoiesis and functions as a leukemia suppressor EKLUND, ELIZABETH NORTHWESTERN UNIVERSITY AT CHICAGO IL $342,815
Childhood Leukemia 2019 NCI 2R01CA174793-06A1 BET bromodomain inhibition as targeted therapy in acute myeloid leukemia VAKOC, CHRISTOPHER COLD SPRING HARBOR LABORATORY NY $552,186
Childhood Leukemia 2019 NCI 1R01CA226172-01A1 Developing Bioinformatic and Microfluidic Single Cell Methods for Studying Intratumoral Heterogeneity in Acute Myeloid Leukemia PAGUIRIGAN, AMY FRED HUTCHINSON CANCER RESEARCH CENTER WA $634,257
Childhood Leukemia 2019 NCI 5R01CA142714-07 Predictors of Myelodysplastic Syndrome in Minnesota POYNTER, JENNY UNIVERSITY OF MINNESOTA MN $557,106
Childhood Leukemia 2019 NCI 5R01CA204308-05 Modulating signaling pathways in endothelial cells to abate leukemic progression BUTLER, JASON HACKENSACK UNIVERSITY MEDICAL CENTER NJ $392,962
Childhood Leukemia 2019 NCI 2R01CA183252-06 DNMT3A in Development of Hematologic Malignancies GOODELL, MARGARET BAYLOR COLLEGE OF MEDICINE TX $533,242
Childhood Leukemia 2019 NCI 1R01CA227830-01A1 Targeting the Unfolded Protein Response in Leukemia Biology and Chemotherapy Resistance SYKES, STEPHEN RESEARCH INST OF FOX CHASE CAN CTR PA $418,613
Childhood Leukemia 2019 NCI 5R01CA201496-04 Novel RNA-Directed Therapy for the Treatment of Acute Myeloid Leukemia ROSEN, STEVEN BECKMAN RESEARCH INSTITUTE/CITY OF HOPE CA $434,681
Childhood Leukemia 2019 NCI 5R01CA211996-03 Dexrazoxane and Prevention of Anthracycline-Related Cardiomyopathy CHOW, ERIC FRED HUTCHINSON CANCER RESEARCH CENTER WA $627,308
Childhood Leukemia 2019 NCI 1R01CA235622-01 Targeting apoptosis in high-risk AML and MDS with BCL-2 inhibitor Venetoclax and optimized 10-day Decitabine regimen KONOPLEVA, MARINA UNIVERSITY OF TX MD ANDERSON CAN CTR TX $380,060
Childhood Leukemia 2019 NCI 5R01CA193235-05 Metabolic Regulation in Leukemia-Initatiating Cells NAKADA, DAISUKE BAYLOR COLLEGE OF MEDICINE TX $448,325
Childhood Leukemia 2019 NCI 5R01CA204044-03 Regulation of TAL1/SCL in T-Cell Leukemia HUANG, SUMING PENNSYLVANIA STATE UNIV HERSHEY MED CTR PA $305,650
Childhood Leukemia 2019 NCI 5R01CA228478-02 Congenital cytomegalovirus infection, KIR genotypes, and acute lymphoblastic leukemia SPECTOR, LOGAN UNIVERSITY OF MINNESOTA MN $454,432
Childhood Leukemia 2019 NIAID 1R03AI137605-01A1 Generation of a Tal1 fluorescent reporter allele for studies on hematopoiesis and leukemogenesis KEE, BARBARA UNIVERSITY OF CHICAGO IL $81,000
Childhood Leukemia 2019 NHLBI 5R01HL136504-03 TEMPORAL CHANGES IN MECHANISMS OF HSC SELF-RENEWAL AND MYELOID LEUKEMOGENESIS MAGEE, JEFFREY WASHINGTON UNIVERSITY MO $381,250
Childhood Leukemia 2019 NCI 5R01CA190661-04 Novel Biomarkers to Risk-Stratify AML Patients with NPM1^Pos/FLT3-IT^Neg Genotype STIREWALT, DEREK FRED HUTCHINSON CANCER RESEARCH CENTER WA $504,672
Childhood Leukemia 2019 NCI 5R01CA194923-05 Long non-coding RNAs in hematopoiesis and blood malignancy AIFANTIS, IANNIS NEW YORK UNIVERSITY SCHOOL OF MEDICINE NY $443,806
Childhood Leukemia 2019 NCI 5R01CA206210-04 Therapeutic targeting of glutamine metabolism in MDS KONOPLEVA, MARINA UNIVERSITY OF TX MD ANDERSON CAN CTR TX $467,092
Childhood Leukemia 2019 NCI 5R01CA176803-05 Targeted- and timed-releasing nanotherapeutics against leukemia stem cells PAN, CHONG-XIAN UNIVERSITY OF CALIFORNIA AT DAVIS CA $348,363
Childhood Leukemia 2019 NCI 5K08CA201611-03 DEFINING THE ROLE OF DOT1L IN DNMT3A-MUTANT LEUKEMIA RAU, RACHEL BAYLOR COLLEGE OF MEDICINE TX $162,148
Childhood Leukemia 2019 NCI 5R01CA172443-06 Targeting NEDD8-Mediated Protein Turnover in AML CAREW, JENNIFER UNIVERSITY OF ARIZONA AZ $278,060
Childhood Leukemia 2019 NHLBI 5K08HL127269-05 Bone Marrow Microenvironmental Expression of Cytochrome P450 Enzymes GHIAUR, GABRIEL JOHNS HOPKINS UNIVERSITY MD $171,720
Childhood Leukemia 2019 NHLBI 5F30HL132613-06 Characterizing the Novel Protein C15orf65 HOWE, RUTH ALBERT EINSTEIN COLLEGE OF MEDICINE NY $23,044
Childhood Leukemia 2019 NCI 5R01CA223194-02 RIP1/RIP3-Calpain-Stat3 and NF-kappa B pathways in AML pathogenesis and treatment ZHANG, JIWANG LOYOLA UNIVERSITY CHICAGO IL $329,342
Childhood Leukemia 2019 NCI 1F30CA236197-01 Understanding the mechanism of bone marrow stromal cell-mediated protection of FLT3-ITD AML from FLT3-targeted therapy PARK, HAE UNIVERSITY OF COLORADO DENVER CO $33,244
Childhood Leukemia 2019 NCI 5F31CA228391-02 Nanoparticle mediated microenvironmental targeting of CCL3 signaling for the treatment of acute myelogenous leukemia ACKUN-FARMMER, MARIAN UNIVERSITY OF ROCHESTER NY $30,300
Childhood Leukemia 2019 NCI 5R01CA216352-03 In Vivo Functional Analysis of Chromosome 7q22 Deletions in Myeloid Malignancies SHANNON, KEVIN UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $328,511
Childhood Leukemia 2019 NCI 5R37CA227656-02 The phosphatase PRL3 as a MYC target and pro-survival oncogene in Acute Lymphoblastic Leukemia BLACKBURN, JESSICA UNIVERSITY OF KENTUCKY KY $339,487
Childhood Leukemia 2019 NCI 1F30CA236131-01 Differentiation-Dependent Targeting of Glycosylated Polyketides in Clonal Hematopoietic Disorders REISMAN, BENJAMIN VANDERBILT UNIVERSITY TN $29,696
Childhood Leukemia 2019 NCI 1F32CA236425-01 Discovery of compounds and genes that regulate cancer's epigenome, using combinatorial screening in a nanodrop-microwell platform ACKERMAN, CHERI BROAD INSTITUTE, INC. MA $61,610
Childhood Leukemia 2019 NCI 5K07CA218362-02 Integrative Molecular Epidemiology of Neurocognitive Outcomes in Acute Lymphoblastic Leukemia BROWN, AUSTIN BAYLOR COLLEGE OF MEDICINE TX $140,860
Childhood Leukemia 2019 NCI 1R01CA232317-01A1 Pre-BCR and STAT5 Signaling in Acute Lymphoblastic Leukemia FARRAR, MICHAEL UNIVERSITY OF MINNESOTA MN $383,812
Childhood Leukemia 2019 NCI 5R01CA098571-15 Molecular Mechanisms of eIF4E mediated transformation BORDEN, KATHERINE UNIVERSITY OF MONTREAL CANADA $220,245
Childhood Leukemia 2019 NCI 5R01CA201230-05 The role of H3K79 methylation in IDH-mutant leukemia BERNT, KATHRIN CHILDREN'S HOSP OF PHILADELPHIA PA $423,410
Childhood Leukemia 2019 NHLBI 1R01HL146137-01 Targeting Novel Pathways in JMML KAPUR, REUBEN INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS IN $534,541
Childhood Leukemia 2019 NCI 5P30CA006973-56 8084 Hematologic Malignancies and BMT Program - 02 AMBINDER, RICHARD JOHNS HOPKINS UNIVERSITY MD $55,387
Childhood Leukemia 2019 NCI 2R01CA134777-06A1 Role of Shp2 in FLT3-ITD induced leukemogenesis KAPUR, REUBEN INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS IN $374,063
Childhood Leukemia 2019 NHLBI 5R01HL131444-05 The role of EVI1-induced DNA hypermethylation in Leukemogenesis QIAN, ZHIJIAN UNIVERSITY OF FLORIDA FL $376,869
Childhood Leukemia 2019 NCI 5R01CA216421-03 The cohesin complex as a tumor suppressor in myeloid leukemia AIFANTIS, IANNIS NEW YORK UNIVERSITY SCHOOL OF MEDICINE NY $489,840
Childhood Leukemia 2019 NCI 5R01CA197991-04 Determining the Role of Metabolism in Resistance in Acute Myeloid Leukemia PARDEE, TIMOTHY WAKE FOREST UNIVERSITY HEALTH SCIENCES NC $343,925
Childhood Leukemia 2019 NHLBI 5R01HL129472-05 Selection of Allogeneic Hematopoietic Cell Donor Based on KIR and HLA Genotypes HSU, KATHARINE SLOAN-KETTERING INST CAN RESEARCH NY $480,567
Childhood Leukemia 2019 NCI 5R01CA101774-17 Mechanisms of Leukemogenesis in Down Syndrome CRISPINO, JOHN NORTHWESTERN UNIVERSITY AT CHICAGO IL $327,592
Childhood Leukemia 2019 NCI 5R01CA193776-05 Improving risk allocation and developing novel therapies for children with T-ALL TEACHEY, DAVID CHILDREN'S HOSP OF PHILADELPHIA PA $575,456
Childhood Leukemia 2019 NCI 5U54CA193419-05 7381 Project 2: Molecular Modulation of Chromatin and Nuclear Structure in Cancer LICHT, JONATHAN NORTHWESTERN UNIVERSITY AT CHICAGO IL $522,336
Childhood Leukemia 2019 NCI 5R01CA190509-05 The function of cyclin C in tumorigenesis SICINSKI, PETER DANA-FARBER CANCER INST MA $439,962
Childhood Leukemia 2019 NCI 5U54CA193461-05 7298 Project 1: Clonal Dynamics Guiding Curative Therapies for Acute Myeloid Leukemia SCADDEN, DAVID MASSACHUSETTS GENERAL HOSPITAL MA $456,560
Childhood Leukemia 2019 NCI 5R01CA213062-03 Molecular mechanisms of Nutrient sensing in cancer HAIGIS, MARCIA HARVARD MEDICAL SCHOOL MA $363,015
Childhood Leukemia 2019 NCI 5R00CA197869-05 Functional dissection of oncogenic enhancers HERRANZ BENITO, DANIEL RBHS -CANCER INSTITUTE OF NEW JERSEY NJ $249,000
Childhood Leukemia 2019 NCI 5P01CA018029-43 8718 Specific Adoptive Immunotherapy of AML with Engineered CD8+ T Cells GREENBERG, PHILIP FRED HUTCHINSON CANCER RESEARCH CENTER WA $815,880
Childhood Leukemia 2019 NCI 5R01CA213912-03 Targeting CK2 oncogenic pathway to overcome drug resistance in high-risk leukemia DOVAT, SINISA PENNSYLVANIA STATE UNIV HERSHEY MED CTR PA $343,259
Childhood Leukemia 2019 NCI 5F31CA217140-03 Novel mechanisms and therapeutic strategies of refractory leukemia MELGAR, KATELYN CINCINNATI CHILDRENS HOSP MED CTR OH $37,696
Childhood Leukemia 2019 NCI 5R01CA212190-03 Longitudinal, multimodal assessment of neuropsychological functioning in children diagnosed with high-risk acute lymphoblastic leukemia (HR-ALL): Using early changes to predict later impairment HARDY, KRISTINA CHILDREN'S RESEARCH INSTITUTE DC $352,062
Childhood Leukemia 2019 NCI 5R01CA213138-03 CD25-mediated feedback control of BCR-signaling and its oncogenic mimics MUSCHEN, MARKUS BECKMAN RESEARCH INSTITUTE/CITY OF HOPE CA $383,865
Childhood Leukemia 2019 NCI 5R01CA216815-03 Improving the disposition of antileukemic asparaginase after drug-induced immunotoxicity FERNANDEZ, CHRISTIAN UNIVERSITY OF PITTSBURGH AT PITTSBURGH PA $312,527
Childhood Leukemia 2019 NCI 5R00CA188595-05 Determining the role of DNMT-interacting RNAs in myeloid disorders DI RUSCIO, ANNALISA BETH ISRAEL DEACONESS MEDICAL CENTER MA $249,000
Childhood Leukemia 2019 NCI 5R01CA181050-06 KIR-FAVORABLE HAPLOIDENTICAL TRANSPLANTATION IN CHILDREN PULSIPHER, MICHAEL CHILDREN'S HOSPITAL OF LOS ANGELES CA $283,072
Childhood Leukemia 2019 NCI 5R01CA224436-02 MLL Family Histone Methyltransferases in Myeloid Leukemia ERNST, PATRICIA UNIVERSITY OF COLORADO DENVER CO $397,815
Childhood Leukemia 2019 NCI 2P30CA023100-33 7846 Hematologic Malignancies KIPPS, THOMAS UNIVERSITY OF CALIFORNIA, SAN DIEGO CA $32,486
Childhood Leukemia 2019 NCI 2P01CA023766-39A1 8178 Project 6: Clinical Trials Focusing on Microbiota and Novel Cell Therapies GIRALT, SERGIO SLOAN-KETTERING INST CAN RESEARCH NY $393,942
Childhood Leukemia 2019 NCI 5R01CA104509-15 Molecular Mechanism of Leukemogenesis Involving AML1-ETO ZHANG, DONG-ER UNIVERSITY OF CALIFORNIA, SAN DIEGO CA $321,373
Childhood Leukemia 2019 NCI 5U01CA214116-03 Proteogenomic Translational Research Center for Clinical Proteomic RODLAND, KARIN BATTELLE PACIFIC NORTHWEST LABORATORIES WA $1,329,622
Childhood Leukemia 2019 NCI 5R01CA185687-05 Risk of Pediatric and Adolescent Cancer Associated with Medical Imaging SMITH-BINDMAN, REBECCA UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $1,630,353
Childhood Leukemia 2019 NCI 5K08CA191091-05 Epigenetic mechanisms of drug resistance in T-cell acute lymphoblastic leukemia KNOECHEL, BIRGIT DANA-FARBER CANCER INST MA $177,120
Childhood Leukemia 2019 NCI 5R01CA175008-07 Understanding and predicting relapse in acute myeloid leukemia RADICH, JERALD FRED HUTCHINSON CANCER RESEARCH CENTER WA $405,460
Childhood Leukemia 2019 NIGMS 1R01GM132596-01 Functional crosstalk between the Fanconi Anemia and ATRX/DAXX histone chaperone pathways SOBECK, ALEXANDRA UNIVERSITY OF MINNESOTA MN $322,282
Childhood Leukemia 2019 NCI 5R01CA198089-05 Understanding and Targeting Chemotherapy Resistance in Acute Myeloid Leukemia CARROLL, MARTIN UNIVERSITY OF PENNSYLVANIA PA $643,241
Childhood Leukemia 2019 NCI 5R01CA201069-04 Pathway Specific Combinational Therapy in Poor Prognosis B-Lineage Acute Lymphoblastic Leukemia OPFERMAN, JOSEPH ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $398,287
Childhood Leukemia 2019 NCI 5F31CA221002-03 Engineering chimeric antigen receptors with VLR-mediated cancer recognition in CD5 edited gamma delta T cells FLEISCHER, LAUREN EMORY UNIVERSITY GA $45,016
Childhood Leukemia 2019 NHLBI 5UG1HL069274-19 Blood and Marrow Transplant Clinical Trials Network KURTZBERG, JOANNE DUKE UNIVERSITY NC $184,109
Childhood Leukemia 2019 NHLBI 5UG1HL069290-19 ALT-803 (IL-15/IL-15Rα-Fc) maintenance after allogeneic transplantation for AML BRUNSTEIN, CLAUDIO UNIVERSITY OF MINNESOTA MN $184,800
Childhood Leukemia 2019 NCI 1U01CA225730-01A1 Analysis of E-selectin Ligands of Human Acute Leukemia Cells and their Biology in Leukemogenesis SACKSTEIN, ROBERT FLORIDA INTERNATIONAL UNIVERSITY FL $625,763
Childhood Leukemia 2019 NCI 1K08CA237627-01 Tumor suppressor roles of TFEB in the development and maintenance of myeloid leukemia YUN, SEONGSEOK H. LEE MOFFITT CANCER CTR & RES INST FL $238,752
Childhood Leukemia 2019 NCI 1P01CA225618-01A1 5379 Antigen Specific T Cells BOLLARD, CATHERINE JOHNS HOPKINS UNIVERSITY MD $221,290
Childhood Leukemia 2019 NIA 1U01AG066100-01 Determinants of CD8+ T Cell Aging and Reduced Function in B Cell Cancer JUNE, CARL UNIVERSITY OF PENNSYLVANIA PA $121,438
Childhood Leukemia 2019 NCI 5K08CA190815-05 REGULATORY MECHANISMS OF HOX GENE EXPRESSION IN ACUTE MYELOID LEUKEMIA SPENCER, DAVID WASHINGTON UNIVERSITY MO $166,298
Childhood Leukemia 2019 NCI 5R01CA194206-04 Transporters and hematopoietic toxicity SCHUETZ, JOHN ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $470,030
Childhood Leukemia 2019 NCI 5R01CA187318-05 Molecular understanding of cytokine-Ras signals in leukemic bone marrow ROOSE, JEROEN UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $343,163
Childhood Leukemia 2019 NCI 5R01CA202025-04 Mapping cancer micro-environments for acute leukemia AIFANTIS, IANNIS NEW YORK UNIVERSITY SCHOOL OF MEDICINE NY $441,979
Childhood Leukemia 2019 NCI 5R01CA193478-04 Web-based Physical Activity Intervention for Children with ALL NESS, KIRSTEN ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $512,890
Childhood Leukemia 2019 NCI 5R01CA201444-04 Adipocytes are Important Players in the Acute Lymphoblastic Leukemia Microenvironment MITTELMAN, STEVEN UNIVERSITY OF CALIFORNIA LOS ANGELES CA $355,328
Childhood Leukemia 2019 NCI 5F30CA221109-03 Epigenetic Regulation in High-Risk Leukemia PAYNE, JONATHON PENNSYLVANIA STATE UNIV HERSHEY MED CTR PA $50,016
Childhood Leukemia 2019 NHLBI 5R01HL076712-12 Role of FA Proteins in Hematopoiesis PANG, QISHEN CINCINNATI CHILDRENS HOSP MED CTR OH $397,500
Childhood Leukemia 2019 NHLBI 5R01HL132921-03 Mitotic failure in Fanconi anemia: mechanisms and role in carcinogenesis CLAPP, DAVID INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS IN $393,750
Childhood Leukemia 2019 NCI 5P01CA077852-20 5812 Replication Stress Signatures MONNAT, RAYMOND UNIVERSITY OF WASHINGTON WA $290,658
Childhood Leukemia 2019 NCI 5P01CA077852-20 5813 Therapeutic response signatures MAIZELS, NANCY UNIVERSITY OF WASHINGTON WA $195,619
Childhood Leukemia 2019 NCI 5R01CA140522-10 Molecular Mechanisms for the Assembly and Regulation of the MLL1 Core Complex COSGROVE, MICHAEL UPSTATE MEDICAL UNIVERSITY NY $373,207
Childhood Leukemia 2019 NCI 5K08CA201591-03 Targeting the ARHGAP25 pathway in acute myelogenous leukemia stem cells WANG, LEO BECKMAN RESEARCH INSTITUTE/CITY OF HOPE CA $169,560
Childhood Leukemia 2019 NHLBI 5UG1HL109526-09 Reduction of Relapse Risk Through Incorporation of Novel Biologic Agents Following Reduced Intensity Haploidentical Donor Transplant for Acute Myeloid Leukemia. BASHEY, ASAD NORTHSIDE HOSPITAL ATLANTA GA $156,263
Childhood Leukemia 2019 NIAID 5K25AI140783-02 Spatial Epigenomic Profiling of Immune Cell Signatures at Subcellular Resolution in Health and Disease COSKUN, AHMET STANFORD UNIVERSITY CA $107,880
Childhood Leukemia 2019 NCI 5R01CA190261-05 The impact of chromosome 17p lesions on leukemogeneis and therapy response LOWE, SCOTT SLOAN-KETTERING INST CAN RESEARCH NY $398,509
Childhood Leukemia 2019 NCI 5K08CA181507-04 Analysis of TET2 function in acute leukemia SHIH, ALAN SLOAN-KETTERING INST CAN RESEARCH NY $180,036
Childhood Leukemia 2019 NCI 5R01CA176745-08 Targeting DOT1L for Degradation in MLL-rearranged Leukemia ARMSTRONG, SCOTT DANA-FARBER CANCER INST MA $391,951
Childhood Leukemia 2019 NHLBI 5UG1HL138658-03 Novel Strategies for Assessing and Optimizing Therapy for Minimal Residual Disease after Allogeneic Transplantation for AML and MDS MAZIARZ, RICHARD OREGON HEALTH & SCIENCE UNIVERSITY OR $186,595
Childhood Leukemia 2019 NCI 5R37CA226433-02 Integration of epigenetic and non-coding RNA mechanisms in leukemia MEYER, SARA THOMAS JEFFERSON UNIVERSITY PA $346,144
Childhood Leukemia 2019 NHLBI 5K08HL138142-02 Investigation of ERBB2 and ERBB3 in hematopoiesis and predisposition to hematologic disease BRAUNSTEIN, EVAN JOHNS HOPKINS UNIVERSITY MD $172,530
Childhood Leukemia 2019 NCI 5R01CA036401-36 Pharmacogenomics of Childhood Leukemia ALL EVANS, WILLIAM ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $704,703
Childhood Leukemia 2019 NCI 5R35CA197561-05 Molecular Pathogenesis of Acute Myeloid Leukemia LEY, TIMOTHY WASHINGTON UNIVERSITY MO $886,559
Childhood Leukemia 2019 NCI 5R21CA223409-02 Treatment of Acute Myeloid Leukemia with C2-Set Domain-Specific CD33 Antibodies WALTER, ROLAND FRED HUTCHINSON CANCER RESEARCH CENTER WA $222,789
Childhood Leukemia 2019 NCI 5R21CA223439-02 Targeting MCJ/DNAJC15 and the mitochondrial electron transport chain in acute myeloid leukemia DEGREGORI, JAMES UNIVERSITY OF COLORADO DENVER CO $191,087
Childhood Leukemia 2019 NHLBI 5R01HL130995-04 Germline mutations of PTPN11 (SHP-2) in the stem cell microenvironment QU, CHENG-KUI EMORY UNIVERSITY GA $390,000
Childhood Leukemia 2019 NHLBI 5UG1HL109137-09 A Phase II Study of Cytokine Induced Memory-like (CIML) Natural Killer (NK) Cell Adoptive Therapy after Haploidentical Donor Hematopoietic Cell Transplantation. WESTERVELT, PETER WASHINGTON UNIVERSITY MO $175,863
Childhood Leukemia 2019 NCI 5R35CA210030-04 Integrating Transforming Approaches to Identify and Target New Vulnerabilities in Cancer STEGMAIER, KIMBERLY DANA-FARBER CANCER INST MA $1,015,049
Childhood Leukemia 2019 NCI 5K08CA212252-03 Overcoming resistance in BCR-ABL-rearranged acute lymphoblastic leukemia MURAKAMI, MARK DANA-FARBER CANCER INST MA $177,120
Childhood Leukemia 2019 NCI 5R01CA173636-07 Role of TET2 mutations in malignant transformation and acute myeloid leukemia LEVINE, ROSS SLOAN-KETTERING INST CAN RESEARCH NY $620,011
Childhood Leukemia 2019 NIGMS 5P20GM103548-09 5159 Exploring the origins of childhood leukemia: investigating transcriptional networks in hematopoiesis and acute leukemia MILANOVICH, SAMUEL SANFORD RESEARCH/USD SD $291,031
Childhood Leukemia 2019 NCI 5R01CA190473-05 Targeting Chk1 in Acute Myeloid Leukemia KARNITZ, LARRY MAYO CLINIC ROCHESTER MN $352,801
Childhood Leukemia 2019 NCI 5U01CA199000-05 Pediatric Preclinical Testing Consortium - Leukemia LOCK, RICHARD UNIVERSITY OF NEW SOUTH WALES AUSTRA $387,584
Childhood Leukemia 2019 NHLBI 5R01HL130937-04 Genetic characterization of osteoblast-induced leukemias KOUSTENI, STAVROULA COLUMBIA UNIVERSITY HEALTH SCIENCES NY $461,485
Childhood Leukemia 2019 NCI 5K12CA090433-18 Pediatric Oncology Clinical Research Training Program BLANEY, SUSAN BAYLOR COLLEGE OF MEDICINE TX $949,109
Childhood Leukemia 2019 NCI 5R00CA197498-06 Epigenetic mechanisms for oncogene silencing in MLL-rearranged leukemia CHEN, CHUN-WEI BECKMAN RESEARCH INSTITUTE/CITY OF HOPE CA $249,000
Childhood Leukemia 2019 NIDDK 5F30DK108532-05 microRNA-22 and the microRNA-22/TET2 Network as Regulators of the Cell Fate Decision in Hematopoietic Stem Cells and in the Development of Myelodysplastic Syndrome. WEISS, CARY ALBERT EINSTEIN COLLEGE OF MEDICINE NY $50,016
Childhood Leukemia 2019 NCI 1R01CA229875-01A1 Mechanisms and targeting of inflammatory cytokine-driven expansion and progression in AML AGARWAL, ANUPRIYA OREGON HEALTH & SCIENCE UNIVERSITY OR $349,698
Childhood Leukemia 2019 NCI 5K08CA194256-05 Chimeric Antigen Receptor T cell Therapy for Acute Myeloid Leukemia (AML) GILL, SAAR UNIVERSITY OF PENNSYLVANIA PA $167,832
Childhood Leukemia 2019 NIDDK 2R01DK098808-06A1 Synergestic roles of SRF2 and RUNX1 in blood cell development and pathology ZHANG, DONG-ER UNIVERSITY OF CALIFORNIA, SAN DIEGO CA $650,270
Childhood Leukemia 2019 NCI 5R01CA204396-04 Aberrant signaling in acute myeloid leukemia KENTSIS, ALEX SLOAN-KETTERING INST CAN RESEARCH NY $467,215
Childhood Leukemia 2019 NCI 5R21CA229922-02 The role germline polymorphisms on ALL susceptibility DUPUY, ADAM UNIVERSITY OF IOWA IA $96,520
Childhood Leukemia 2019 NCI 1R01CA232147-01A1 USP18 in Cancer Development ZHANG, DONG-ER UNIVERSITY OF CALIFORNIA, SAN DIEGO CA $376,989
Childhood Leukemia 2019 NCI 5R21CA230065-02 Opportunities for targeted therapies generated by APOBEC3A activity in acute myeloid leukemia WEITZMAN, MATTHEW CHILDREN'S HOSP OF PHILADELPHIA PA $217,726
Childhood Leukemia 2019 NCI 5F31CA232480-02 The Impact of CD82 Expression on Acute Myeloid Leukemia Chemosensitivity and Disease Relapse FLOREN, MUSKAN UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR NM $33,396
Childhood Leukemia 2019 NHLBI 5R21HL143096-02 Personalized molecular approaches to disease monitoring and maintenance therapies for Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML) patients undergoing allogeneic bone marrow transp GONDEK, LUKASZ JOHNS HOPKINS UNIVERSITY MD $122,813
Childhood Leukemia 2019 NCI 5F31CA228324-02 AML1-ETO Regulation via the 3'UTR in t(8;21) Acute Myeloid Leukemia JOHNSON, DANIEL UNIVERSITY OF CALIFORNIA, SAN DIEGO CA $38,778
Childhood Leukemia 2019 NCI 5R01CA096899-14 Mechanism(s) of TAL1-and NOTCH1-mediated Leukemogenesis KELLIHER, MICHELLE UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $347,289
Childhood Leukemia 2019 NCI 5R01CA204231-03 Cohesin Mutations in Acute Myelogenous Leukemia RAO, SRIDHAR VERSITI WISCONSIN, INC. WI $365,143
Childhood Leukemia 2019 NCI 5R01CA187903-05 CHARACTERIZATION OF THE MOLECULAR INTERPLAY BETWEEN HOXA9 AND OGT IN ACUTE LEUKEMIA RUAL, JEAN-FRANCOIS UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $343,925
Childhood Leukemia 2019 NCI 5R01CA204895-03 Leukemia stem cell polarity and differentiation therapy MULLOY, JAMES CINCINNATI CHILDRENS HOSP MED CTR OH $429,520
Childhood Leukemia 2019 NHLBI 7R01HL128173-05 Multiscale Modeling of Myelodysplastic Syndromes COREY, SETH CLEVELAND CLINIC LERNER COM-CWRU OH $847,513
Childhood Leukemia 2019 NCI 1K08CA230172-01A1 Lineage identification and targeted therapeutics in acute leukemia GLASS, JACOB SLOAN-KETTERING INST CAN RESEARCH NY $300,766
Childhood Leukemia 2019 NCI 5R35CA197697-05 Mechanisms of regulation by RNA in acute myeloid leukemia TENEN, DANIEL BETH ISRAEL DEACONESS MEDICAL CENTER MA $1,010,917
Childhood Leukemia 2019 NIEHS 5R24ES028524-03 Support for Infrastructure of Childhood Leukemia Environmental Research METAYER, CATHERINE UNIVERSITY OF CALIFORNIA BERKELEY CA $377,828
Childhood Leukemia 2019 NIGMS 5P50GM115279-05 7544 CPML - Core A: Administrative Core RELLING, MARY ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $204,480
Childhood Leukemia 2019 NIGMS 5P50GM115279-05 7545 CPML - Core B: Cell & Molecular Core CREWS, KRISTINE ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $348,036
Childhood Leukemia 2019 NIGMS 5P50GM115279-05 7546 CPML - Core C: Bioinformatics & Biostatistical Core ZHANG, JINGHUI ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $596,873
Childhood Leukemia 2019 NIGMS 5P50GM115279-05 7547 CPML - Project 1: Genome-wide Studies of ALL Response MULLIGHAN, CHARLES ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $703,371
Childhood Leukemia 2019 NIGMS 5P50GM115279-05 7548 CPML - Project 2: Genome-wide Studies of ALL Drug Sensitivity EVANS, WILLIAM ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $714,178
Childhood Leukemia 2019 NIGMS 5P50GM115279-05 7549 CPML - Project 3: Genome-wide Studies of Adverse Effects RELLING, MARY ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $351,828
Childhood Leukemia 2019 NIBIB 1R21EB026560-01A1 Aptamer-Modified POSH Inhibitor Micelles as a Novel Leukemia Treatment Modality ULERY, BRET UNIVERSITY OF MISSOURI-COLUMBIA MO $298,013
Childhood Leukemia 2019 NCI 5K08CA230306-02 COMPRENDO: Adaptation and Implementation of a Peer-Navigation Intervention to Improve Research Literacy and Diversity in Pediatric Leukemia Clinical Trials ARISTIZABAL, PAULA UNIVERSITY OF CALIFORNIA, SAN DIEGO CA $254,821
Childhood Leukemia 2019 NCI 5R35CA210064-04 Mechanisms and Vulnerabilities of Aberrant Transcriptional Enhancers in Cancer LOOK, A. DANA-FARBER CANCER INST MA $1,015,048
Childhood Leukemia 2019 NCI 5R01CA222349-02 Non-canonical Caspase-8 Activation on Autophagosomal Membranes WANG, HONG-GANG PENNSYLVANIA STATE UNIV HERSHEY MED CTR PA $338,167
Childhood Leukemia 2019 NCI 5R01CA090576-19 STUDIES OF BCR-ABL LEUKEMOGENESIS IN MICE VAN ETTEN, RICHARD UNIVERSITY OF CALIFORNIA-IRVINE CA $284,743
Childhood Leukemia 2019 NCI 1R01CA232263-01A1 Enhancer Dysregulation in AML DOU, YALI UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $529,271
Childhood Leukemia 2019 NCI 5U01CA217862-03 Functional Genomic Discovery of Pathway Targeted and Immune Modulatory Therapeutic Combinations in Hematologic Malignancies DRUKER, BRIAN OREGON HEALTH & SCIENCE UNIVERSITY OR $1,236,369
Childhood Leukemia 2019 NCI 5R35CA210104-03 Epigenetic regulation of cellular plasticity and cancer cell fate SHI, YANG BOSTON CHILDREN'S HOSPITAL MA $1,030,140
Childhood Leukemia 2019 NCI 5R01CA140729-09 Drug resistant pathways in relapsed acute lymphoblastic leukemia (ALL) CARROLL, WILLIAM NEW YORK UNIVERSITY SCHOOL OF MEDICINE NY $447,228
Childhood Leukemia 2019 NCI 5R01CA216981-03 Molecular characterization and targeting of NT5C2 mutations in acute lymphoblastic leukemia FERRANDO, ADOLFO COLUMBIA UNIVERSITY HEALTH SCIENCES NY $371,168
Childhood Leukemia 2019 NCI 5R01CA230618-02 Understanding Ikaros molecular functions for targeted therapies of pre-B ALL SCHJERVEN, HILDE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $349,469
Childhood Leukemia 2019 NCI 5R50CA211782-03 COMPREHENSIVE INFORMATIC ANALYSES OF AML GENOMES AND EPIGENOMES MILLER, CHRISTOPHER WASHINGTON UNIVERSITY MO $107,259
Childhood Leukemia 2019 NCI 5R01CA211734-03 Oncogenic pathways and therapeutic targets in T cell acute lymphoblastic leukemia LANGENAU, DAVID MASSACHUSETTS GENERAL HOSPITAL MA $379,427
Childhood Leukemia 2019 NCI 5F30CA210518-04 Evaluation of Bruton’s Tyrosine Kinase and p110 delta in Mutant Shp2-Induced JMML DENG, LISA INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS IN $50,016
Childhood Leukemia 2019 NCI 5F30CA224687-02 Identification of epigenetic subclones in lymphomas and leukemias FONG, JERRY WASHINGTON UNIVERSITY MO $30,926
Childhood Leukemia 2019 NCI 5R01CA213129-03 Sequestration and deactivation of anthracycline by adipocytes in the leukemia microenvironment MITTELMAN, STEVEN UNIVERSITY OF CALIFORNIA LOS ANGELES CA $375,060
Childhood Leukemia 2019 NCI 5K01CA188151-05 Targeted Alpha Radioimmunotherapy with Haploidentical Bone Marrow Transplantation for AML OROZCO, JOHNNIE FRED HUTCHINSON CANCER RESEARCH CENTER WA $169,020
Childhood Leukemia 2019 NCI 5R50CA211404-04 Therapeutic insights through patient derived leukemia xenografts WUNDERLICH, MARK CINCINNATI CHILDRENS HOSP MED CTR OH $172,232
Childhood Leukemia 2019 NCI 5R35CA210065-03 Molecular pathways and targeted therapies in human leukemia FERRANDO, ADOLFO COLUMBIA UNIVERSITY HEALTH SCIENCES NY $931,200
Childhood Leukemia 2019 NIEHS 5K01ES026842-05 Connecting Single Cell Heterogeneity to Clinical Descriptors of Clonal Evolution in Acute Myeloid Leukemia PAGUIRIGAN, AMY FRED HUTCHINSON CANCER RESEARCH CENTER WA $119,975
Childhood Leukemia 2019 NCI 5P50CA107399-12 5662 Therapy-related leukemia following autologous transplantation for lymphoma BHATIA, SMITA BECKMAN RESEARCH INSTITUTE/CITY OF HOPE CA $570,915
Childhood Leukemia 2019 NCI 5R01CA209829-04 Targeting CRLF2 and Ikaros Alterations to Reduce Health Disparities in Childhood Leukemia PAYNE, KIMBERLY LOMA LINDA UNIVERSITY CA $349,730
Childhood Leukemia 2019 NIGMS 5P20GM121322-02 8733 Immunometabolic regulation of leukemic niche-donor cell interaction DU, WEI WEST VIRGINIA UNIVERSITY WV $257,780
Childhood Leukemia 2019 NCI 5R01CA166835-08 Targeted Therapy for t(8;21)+ AML NIMER, STEPHEN UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $335,013
Childhood Leukemia 2019 NCI 2R01CA121192-11 Targeting Novel Protein Complexes for the Treatment of Acute Myeloid Leukemia PLATANIAS, LEONIDAS NORTHWESTERN UNIVERSITY AT CHICAGO IL $300,200
Childhood Leukemia 2019 NHLBI 5F31HL143844-02 Investigating the role of ZBTB33 loss in clonal hematopoiesis and hematologic malignancies BEAUCHAMP, ELLEN HARVARD MEDICAL SCHOOL MA $32,704
Childhood Leukemia 2019 NCI 5R01CA219150-03 Anticancer peptide therapeutics LU, WUYUAN UNIVERSITY OF MARYLAND BALTIMORE MD $342,815
Childhood Leukemia 2019 NCI 5R01CA219345-03 Small-molecule MDM2 degraders WANG, SHAOMENG UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $611,605
Childhood Leukemia 2019 NCI 5R01CA223165-02 Targeting NAMPT in Acute Myeloid Leukemia LAPALOMBELLA, ROSA OHIO STATE UNIVERSITY OH $456,788
Childhood Leukemia 2019 NCI 1F32CA232402-01A1 Unrestricted A20 activity in acute myeloid leukemia COCHRAN, ASHLEY CINCINNATI CHILDRENS HOSP MED CTR OH $70,430
Childhood Leukemia 2019 NHLBI 5K01HL143153-02 Early Treatment-Related Cardiotoxicity and Subsequent Outcomes in Pediatric Acute Myeloid Leukemia: an Assessment of Development, Progression and Mitigation GETZ, KELLY UNIVERSITY OF PENNSYLVANIA PA $145,152
Childhood Leukemia 2019 NCI 1F30CA239335-01 Defining the stromal landscape that sustains AML drug resistance JOSHI, SUNIL OREGON HEALTH & SCIENCE UNIVERSITY OR $50,016
Childhood Leukemia 2019 NCI 5K07CA211847-04 Material Hardship as a Targetable Measure of Poverty in Pediatric Cancer BONA, KIRA DANA-FARBER CANCER INST MA $133,475
Childhood Leukemia 2019 NCI 5P50CA171963-07 8685 Project 2 - Targeted Therapies for T-ALL. UY, GEOFFREY WASHINGTON UNIVERSITY MO $316,991
Childhood Leukemia 2019 NCI 5P50CA171963-07 8686 Project 3 - Novel Therapies for Spliceosomal-Mutant MDS. WALTER, MATTHEW WASHINGTON UNIVERSITY MO $309,651
Childhood Leukemia 2019 NCI 5P50CA171963-07 8687 Project 4 - Targeting AML using novel bispecific and antibody-drug conjugates. DIPERSIO, JOHN WASHINGTON UNIVERSITY MO $316,988
Childhood Leukemia 2019 NCI 5P50CA171963-07 8688 Project 5 - Memory-like NK cell augmented hematopoietic cell transplantation for AML. FEHNIGER, TODD WASHINGTON UNIVERSITY MO $316,988
Childhood Leukemia 2019 NCI 5R01CA215059-02 The Role of DLST in Leukemogenesis FENG, HUI BOSTON UNIVERSITY MEDICAL CAMPUS MA $366,114
Childhood Leukemia 2019 NCI 1F31CA239365-01 Predicting Post-treatment Relapse in Pediatric Acute Myeloid Leukemia Using Single-cell Proteomics KEYES, TIMOTHY STANFORD UNIVERSITY CA $38,650
Childhood Leukemia 2019 NCI 5R01CA195732-04 The Role of MMSET in the Pathogenesis and Progression of Lymphoid Malignancy LICHT, JONATHAN UNIVERSITY OF FLORIDA FL $338,378
Childhood Leukemia 2019 NCI 5P30CA125123-13 8015 Pediatric Cancer Program (Project-007) POPLACK, DAVID BAYLOR COLLEGE OF MEDICINE TX $70,262
Childhood Leukemia 2019 NCI 5R01CA181024-06 Prevention of bone loss after pediatric hematopoietic cell transplantation SARAFOGLOU, KYRIAKIE UNIVERSITY OF MINNESOTA MN $429,176
Childhood Leukemia 2019 NCI 5R01CA207530-04 The Role of LMO2 in the Pathogenesis of T-cell Leukemia DAVE, UTPAL INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS IN $349,694
Childhood Leukemia 2019 NCI 5R50CA211534-04 Development of novel therapies for megakaryocytic malignancies WEN, QIANG NORTHWESTERN UNIVERSITY AT CHICAGO IL $130,753
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