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RCDC

Project Listing by Category


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CategoryFYFunding ICProject NumberSub Project #Project TitlePI NameOrg NameState / CountryAmount
Brain Cancer 2019 NCI 5R01CA183854-06 BAYESIAN APPROACHES FOR MISSINGNESS AND CAUSALITY IN CANCER AND BEHAVIOR STUDIES DANIELS, MICHAEL UNIVERSITY OF FLORIDA FL $290,047
Brain Cancer 2019 NINDS 5R01NS085364-05 CSF1 signaling in gliomagenesis COLLIER, LARA UNIVERSITY OF WISCONSIN-MADISON WI $325,726
Brain Cancer 2019 NCI 5R01CA221197-02 White Matter Toxicity and Neurocognitive Outcomes in Pediatric Brain Tumor Patients Treated with Proton Beam Radiation Therapy KAHALLEY, LISA BAYLOR COLLEGE OF MEDICINE TX $778,850
Brain Cancer 2019 NINDS 5R01NS091251-04 Therapeutically relevant targets of Twist1 dimers in glioma ROSTOMILY, ROBERT METHODIST HOSPITAL RESEARCH INSTITUTE TX $353,281
Brain Cancer 2019 NCI 5R01CA194189-05 Genetic Susceptibility to Pediatric Glioma inIndividuals and Diverse populations WIEMELS, JOSEPH UNIVERSITY OF SOUTHERN CALIFORNIA CA $1,013,932
Brain Cancer 2019 NINDS 5R01NS087213-04 A novel STAT3-selective inhibitor for medulloblastoma therapy LIN, JIAYUH UNIVERSITY OF MARYLAND BALTIMORE MD $339,473
Brain Cancer 2019 NINDS 5R01NS073610-07 Targeting Kif11 to Treat Glioblastoma Invasion and Proliferation ROSENFELD, STEVEN MAYO CLINIC JACKSONVILLE FL $574,526
Brain Cancer 2019 NINDS 5R01NS100782-02 Radiation-induced astrocyte dysfunction and cognitive decline UNGVARI, ZOLTAN UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR OK $342,913
Brain Cancer 2019 NICHD 5R01HD086195-04 Smart targeting nano-theranostics for image-guided drug delivery to pediatric brain tumors LI, YUANPEI UNIVERSITY OF CALIFORNIA AT DAVIS CA $325,775
Brain Cancer 2019 NCI 5R01CA183153-07 Characterization of oncogenic FGFR3-TACC3 fusion gene in glioblastoma ZHANG, WEI WAKE FOREST UNIVERSITY HEALTH SCIENCES NC $299,193
Brain Cancer 2019 NCI 5R01CA200624-04 Cytoplasmic Multimerization of the RNA-binding protein HuR is Oncogenic in Glioma NABORS, LOUIS UNIVERSITY OF ALABAMA AT BIRMINGHAM AL $253,739
Brain Cancer 2019 NCI 5R01CA195613-22 Molecular Mechanisms and Therapeutic Approaches to Malignant Gliomas HUNTER, TONY SALK INSTITUTE FOR BIOLOGICAL STUDIES CA $651,432
Brain Cancer 2019 NCI 5R01CA201402-04 The roles of a unique GTP-binding protein/crosslinking enzyme in disease CERIONE, RICHARD CORNELL UNIVERSITY NY $451,697
Brain Cancer 2019 NINDS 5F31NS096908-03 Investigating the Effects of Stem Cell Positional Identity on Brain Tumor Development RUSHING, GABRIELLE VANDERBILT UNIVERSITY TN $29,680
Brain Cancer 2019 NINDS 5K08NS099427-03 Targeting ATRX-Deficient Pediatric GBM KOSCHMANN, CARL UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $163,263
Brain Cancer 2019 NINDS 5R01NS099096-03 A Novel Clinical Challenge in Brain Tumor Immunology: T cell Sequestration FECCI, PETER DUKE UNIVERSITY NC $331,118
Brain Cancer 2019 NINDS 5R01NS099162-03 Biguanide Sensitivity of Glioma Stem Cells DASGUPTA, BIPLAB CINCINNATI CHILDRENS HOSP MED CTR OH $341,398
Brain Cancer 2019 NCI 5R01CA194414-04 The Role of CK2 in Glioblastoma Development BENVENISTE, ETTY UNIVERSITY OF ALABAMA AT BIRMINGHAM AL $326,174
Brain Cancer 2019 NCI 5R01CA203893-04 SUMO1 inhibition compound as a new anticancer drug for glioblastoma therapy HAO, CHUNHAI INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS IN $367,808
Brain Cancer 2019 NCI 5R01CA204136-03 Credentialing murine models for glioblastoma preclinical drug development MILLER, CHRISTOPHER UNIV OF NORTH CAROLINA CHAPEL HILL NC $133,154
Brain Cancer 2019 NCI 5R01CA213441-03 Therapeutic Irradiation and Brain Functions ROSI, SUSANNA UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $344,237
Brain Cancer 2019 NCI 5R01CA158079-09 MRI Assessment of Tumor Perfusion, Permeability and Cellularity QUARLES, CHRISTOPHER ST. JOSEPH'S HOSPITAL AND MEDICAL CENTER AZ $387,498
Brain Cancer 2019 NCI 5R37CA214800-02 Role of Quaking gene in regulating the niche-independent stemness of glioma stem cells HU, JIAN UNIVERSITY OF TX MD ANDERSON CAN CTR TX $355,019
Brain Cancer 2019 NCI 5R01CA084628-27 Telomerase in Development, Senescence and Neoplasia DEPINHO, RONALD UNIVERSITY OF TX MD ANDERSON CAN CTR TX $597,518
Brain Cancer 2019 NINDS 5K08NS099484-03 Leveraging Temozolomide to Improve Treatment Efficacy of Immune Checkpoint Blockade in Glioblastoma RAHMAN, MARYAM UNIVERSITY OF FLORIDA FL $181,980
Brain Cancer 2019 NINDS 5P30NS045892-16 7085 UNC Neuroscience Center Research Cores: Bioinformatics ZYLKA, MARK UNIV OF NORTH CAROLINA CHAPEL HILL NC $184,868
Brain Cancer 2019 NCI 5R01CA190617-05 Itraconazole Analogues to Treat Medulloblastoma HADDEN, MATTHEW UNIVERSITY OF CONNECTICUT STORRS CT $370,476
Brain Cancer 2019 NCI 5F30CA206389-03 The Role of CD147 in Glioblastoma Invasiveness COLANGELO, NICHOLAS RBHS-NEW JERSEY MEDICAL SCHOOL NJ $50,016
Brain Cancer 2019 NCI 5R01CA214749-02 MSC-Derived Exosomes and MicroRNA in Glioma Therapy LANG, FREDERICK UNIVERSITY OF TX MD ANDERSON CAN CTR TX $355,019
Brain Cancer 2019 NINDS 5R01NS099463-03 CCL3 as a Developmental Therapeutic to Enhance Brain Tumor Therapy SAMPSON, JOHN DUKE UNIVERSITY NC $347,813
Brain Cancer 2019 NCI 5R01CA163336-07 Predicting Transcriptional and Epigenetic Networks in Cancer from Sequencing Data SONG, JUN UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN IL $317,385
Brain Cancer 2019 NINDS 5R35NS105068-02 Preclinical development of breakthrough immunotherapy for brain tumors OKADA, HIDEHO UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $719,525
Brain Cancer 2019 NINDS 5R01NS032677-26 Genetically Engineered Viruses for Brain Tumor Therapy MARTUZA, ROBERT MASSACHUSETTS GENERAL HOSPITAL MA $548,365
Brain Cancer 2019 NINDS 5R01NS104339-02 Biosynthetic Metabolic Pathway Regulation of Glioma Growth HJELMELAND, ANITA UNIVERSITY OF ALABAMA AT BIRMINGHAM AL $379,651
Brain Cancer 2019 NHLBI 5R01HL130246-04 Integrating miR-107 into signaling pathways that coordinate neurogenesis and brain vascular permeability NICOLI, STEFANIA YALE UNIVERSITY CT $418,750
Brain Cancer 2019 NCI 5R37CA214955-03 Synthesizing Image-derived Heterogeneity with Genomic measurements for Assessing Disease Aggressiveness in Lower Grade Gliomas RAO, ARVIND UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $496,651
Brain Cancer 2019 NIBIB 5R01EB020613-04 Rapid MRI acquisition for pediatric low-grade gliomas SETSOMPOP, KAWIN MASSACHUSETTS GENERAL HOSPITAL MA $657,791
Brain Cancer 2019 NCI 5K25CA201545-03 Development of microfluidic blood-brain tumor barrier model to screen chemotherapeutic strategies for breast cancer brain metastases LEE, WON JAE STANFORD UNIVERSITY CA $157,167
Brain Cancer 2019 NCI 5R37CA222563-02 Interstitial Fluid Flow Regulates Glioma Cell Invasion MUNSON, JENNIFER VIRGINIA POLYTECHNIC INST AND ST UNIV VA $519,122
Brain Cancer 2019 NEI 5K01ES026832-04 Multi-scale data integration frameworks to improve cancer outcomes ITAKURA, HARUKA STANFORD UNIVERSITY CA $188,952
Brain Cancer 2019 NCI 5R01CA203861-03 Augmented Neurosurgical Navigation Software Using Resting State MRI LEUTHARDT, ERIC WASHINGTON UNIVERSITY MO $264,990
Brain Cancer 2019 NCI 5R01CA223388-02 MOLECULAR DISSECTION OF SEIZURE MICROENVIRONMENT IN MALIGNANT GLIOMA NOEBELS, JEFFREY BAYLOR COLLEGE OF MEDICINE TX $613,164
Brain Cancer 2019 NCI 5P30CA006516-54 5409 Program 30: Neuro-Oncology STILES, CHARLES DANA-FARBER CANCER INST MA $72,080
Brain Cancer 2019 NINDS 5R01NS089575-04 Mechanisms underlying radiation-and chemotherapy induced cognitive impairment. LIMOLI, CHARLES UNIVERSITY OF CALIFORNIA-IRVINE CA $554,836
Brain Cancer 2019 NCI 5P30CA023108-40 5370 Cancer Imaging & Radiobiology (CIR) PAULSEN, KEITH DARTMOUTH COLLEGE NH $70,487
Brain Cancer 2019 NCI 5P30CA023108-40 5371 Immunology & Cancer Immunotherapy (ICI) TURK, MARY JO DARTMOUTH COLLEGE NH $70,043
Brain Cancer 2019 NCI 5R01CA213423-03 High-frequency Irreversible Electroporation (H-FIRE) combinatorial GBM treatment DAVALOS, RAFAEL VIRGINIA POLYTECHNIC INST AND ST UNIV VA $382,130
Brain Cancer 2019 NCI 5R01CA187219-04 Peptide vaccine immunotherapy for children with recurrent low-grade astrocytomas POLLACK, IAN UNIVERSITY OF PITTSBURGH AT PITTSBURGH PA $342,201
Brain Cancer 2019 NINDS 5R35NS105109-02 Molecular Mechanisms of Drug Resistance in Primary Brain Tumors MELLINGHOFF, INGO SLOAN-KETTERING INST CAN RESEARCH NY $600,950
Brain Cancer 2019 NCI 5R01CA195503-05 Nanoparticle Modified Human Fat Derived Mesenchymal Stem Cells for Brain Cancer (Change of Organization Application) QUINONES-HINOJOSA, ALFREDO MAYO CLINIC JACKSONVILLE FL $352,810
Brain Cancer 2019 NCI 5F32CA213966-03 Simultaneous Detection of Proteins and Whole Transcriptomes in Single Cells XU, ALEXANDER INSTITUTE FOR SYSTEMS BIOLOGY WA $62,836
Brain Cancer 2019 NCI 5P30CA014236-45 5313 Cancer Center Isolation Facility Shared Resource KASTAN, MICHAEL DUKE UNIVERSITY NC $133,994
Brain Cancer 2019 NCI 5P30CA014236-45 5327 Cancer Control and Population Sciences Research Program KASTAN, MICHAEL DUKE UNIVERSITY NC $25,545
Brain Cancer 2019 NCI 5P30CA014236-45 5328 Neuro-Oncology Research Program KASTAN, MICHAEL DUKE UNIVERSITY NC $40,784
Brain Cancer 2019 NCI 5R01CA183991-05 Novel role of compensatory proliferation in human brain tumor NAKANO, ICHIRO UNIVERSITY OF ALABAMA AT BIRMINGHAM AL $306,984
Brain Cancer 2019 NIBIB 5R01EB023366-03 Extracellular pH mapping as therapeutic readout of drug delivery in glioblastoma HYDER, DEWAN SYED YALE UNIVERSITY CT $614,739
Brain Cancer 2019 NCI 5R01CA193520-04 The Role of lncRNA MEG3 in Clinically Non-functioning Pituitary Adenomas SOBERMAN, ROY MASSACHUSETTS GENERAL HOSPITAL MA $365,722
Brain Cancer 2019 NCI 5R21CA218309-02 Yoga Intervention for Family Caregivers of Patients with Brain Tumors MILBURY, KATHRIN UNIVERSITY OF TX MD ANDERSON CAN CTR TX $202,536
Brain Cancer 2019 NCI 5F30CA224971-02 Perturbation of Polycomb-mediated gene repression by histone H3 mutations. WEINBERG, DANIEL WEILL MEDICAL COLL OF CORNELL UNIV NY $50,016
Brain Cancer 2019 NCI 5R21CA223757-02 Metabolic MRI for quantifying aerobic glycolysis and immune function in gliomas ELLINGSON, BENJAMIN UNIVERSITY OF CALIFORNIA LOS ANGELES CA $163,850
Brain Cancer 2019 NCI 5F31CA224536-02 Elucidating Reversible Drug Resistance in Glioblastoma NAJM, FADI HARVARD MEDICAL SCHOOL MA $16,960
Brain Cancer 2019 NCI 5R01CA223674-02 Engineering knotted peptide therapeutics for pediatric brain tumor patients OLSON, JAMES FRED HUTCHINSON CANCER RESEARCH CENTER WA $638,218
Brain Cancer 2019 NINDS 5R01NS096756-04 Neuroimmunology of Malignant Brain Tumors: Innate Mechanisms LOWENSTEIN, PEDRO UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $414,676
Brain Cancer 2019 NCI 5R01CA159859-08 Mouse models to discover new drivers of medulloblastoma WECHSLER-REYA, ROBERT SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE CA $724,440
Brain Cancer 2019 NCI 5R35CA197684-04 IKK/NF-kappaB Signaling in Cancer: Therapy, Resistance, and Tumor Initiating Cells BALDWIN, ALBERT UNIV OF NORTH CAROLINA CHAPEL HILL NC $817,442
Brain Cancer 2019 NCI 5P30CA044579-28 5841 Molecular Genetics and Epigenetics Program - GEN STUKENBERG, P. TODD UNIVERSITY OF VIRGINIA VA $33,518
Brain Cancer 2019 NCI 5R01CA221938-02 Multi-site Validation and Application of a Consensus DSC MRI Protocol QUARLES, CHRISTOPHER ST. JOSEPH'S HOSPITAL AND MEDICAL CENTER AZ $317,574
Brain Cancer 2019 NCI 5R01CA221969-02 Improving the efficacy of mTOR inhibition WEISS, WILLIAM UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $568,138
Brain Cancer 2019 NINDS 5R01NS088219-05 Glycolytic regulation of cerebellar development and medulloblastoma tumorigenesis GERSHON, TIMOTHY UNIV OF NORTH CAROLINA CHAPEL HILL NC $327,837
Brain Cancer 2019 NINDS 5R01NS089609-05 Cortical organization of action knowledge before and after brain surgery PILCHER, WEBSTER UNIVERSITY OF ROCHESTER NY $356,247
Brain Cancer 2019 NCI 5F30CA213666-02 PBAF Signaling in Meningioma Tumorigenesis YOUNGBLOOD, MARK YALE UNIVERSITY CT $29,736
Brain Cancer 2019 NINDS 5R01NS096376-03 Cellular plasticity and equilibrium in GBM progression AHMED, ATIQUE NORTHWESTERN UNIVERSITY AT CHICAGO IL $342,103
Brain Cancer 2019 NINDS 5R01NS096956-04 Targeting EphA2 in Glioblastoma WANG, BINGCHENG CASE WESTERN RESERVE UNIVERSITY OH $508,984
Brain Cancer 2019 NINDS 5R21NS106407-02 Targeting TAZ-driven oncogenic signaling in Medulloblastoma YING, MINGYAO HUGO W. MOSER RES INST KENNEDY KRIEGER MD $202,188
Brain Cancer 2019 NCI 2P30CA021765-40 5521 Center for InVivo Imaging and Therapy Shared Resources Core AKERS, WALTER ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $253,719
Brain Cancer 2019 NCI 2P30CA021765-40 5531 Neurobiology and Brain Tumor Program BAKER, SUZANNE ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $67,924
Brain Cancer 2019 NCI 2P50CA190991-06 5853 Administrative Core SAMPSON, JOHN DUKE UNIVERSITY NC $335,213
Brain Cancer 2019 NCI 2P50CA190991-06 5854 Biostatistics and Bioinformatics Core HERNDON, JAMES DUKE UNIVERSITY NC $199,629
Brain Cancer 2019 NCI 2P50CA190991-06 5855 Clinical Trial Operations Core DESJARDINS, ANNICK DUKE UNIVERSITY NC $259,215
Brain Cancer 2019 NCI 2P50CA190991-06 5856 Biorepository, Pathology, and Immune Monitoring Core WEINHOLD, KENT DUKE UNIVERSITY NC $307,969
Brain Cancer 2019 NCI 2P50CA190991-06 5857 Neoantigen immunotherapy in brain tumors using anti-CD27 to deplete regulatory T cells selectively SAMPSON, JOHN DUKE UNIVERSITY NC $256,082
Brain Cancer 2019 NCI 2P50CA190991-06 5858 'Arresting' bone marrow T cell sequestration in patients with GBM FECCI, PETER DUKE UNIVERSITY NC $266,127
Brain Cancer 2019 NCI 2P50CA190991-06 5859 A novel cellular tumor vaccine strategy for mutant IDH1 glioma GUNN, MICHAEL DUKE UNIVERSITY NC $247,407
Brain Cancer 2019 NCI 2P50CA190991-06 5860 Developmental Research Program SAMPSON, JOHN DUKE UNIVERSITY NC $109,668
Brain Cancer 2019 NCI 2P50CA190991-06 5861 Career Enhancement Program SAMPSON, JOHN DUKE UNIVERSITY NC $106,564
Brain Cancer 2019 NCI 5F30CA196110-04 The role of Neuropilin 1 in Glioma Associated Microglia and Macrophages MIYAUCHI, JEREMY STATE UNIVERSITY NEW YORK STONY BROOK NY $50,016
Brain Cancer 2019 NCI 5R21CA223853-02 Stimulated Raman scattering spectroscopic optical coherence tomography (SRS-SOCT) for label-free molecular imaging of brain tumor pathology ROBLES, FRANCISCO GEORGIA INSTITUTE OF TECHNOLOGY GA $182,900
Brain Cancer 2019 NCI 5R01CA177828-05 Elucidating and targeting the molecular foundations of IDH mutant glioma CHAN, TIMOTHY SLOAN-KETTERING INST CAN RESEARCH NY $552,667
Brain Cancer 2019 NINDS 1R21NS103841-01A1 Analyzing Cell-Cell Fusion in Glioblastoma Growth and Progression MCCARTY, JOSEPH UNIVERSITY OF TX MD ANDERSON CAN CTR TX $240,000
Brain Cancer 2019 NCI 5R01CA211080-03 Development of whole-brain in vivo 2HG imaging for precision medicine in mutant IDH glioma ANDRONESI, OVIDIU MASSACHUSETTS GENERAL HOSPITAL MA $358,913
Brain Cancer 2019 NCI 5R01CA218139-02 Medium-chain acyl-coenzyme A dehydrogenase as an essential feeder of glioblastoma multiforme DRAETTA, GIULIO UNIVERSITY OF TX MD ANDERSON CAN CTR TX $353,664
Brain Cancer 2019 NIBIB 5R01EB019934-05 Development and Translation of D-glucose as a Diagnostic Agent for MRI of Cancer VAN ZIJL, PETER HUGO W. MOSER RES INST KENNEDY KRIEGER MD $1,105,725
Brain Cancer 2019 NICHD 5R01HD079568-05 MICROBLEEDS AS A MARKER OF RADIATION-INDUCED BRAIN INJURY IN PEDIATRIC PATIENTS LUPO, JANINE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $498,433
Brain Cancer 2019 NCI 5F30CA200252-04 Cytokine induced RelB/p50 complexes drive mesenchymal glioma progression WATERS, MICHAEL VIRGINIA COMMONWEALTH UNIVERSITY VA $6,236
Brain Cancer 2019 NCI 5R01CA208783-03 Systemic RNA interference to reactivate p53 tumor suppression STEGH, ALEXANDER NORTHWESTERN UNIVERSITY AT CHICAGO IL $343,370
Brain Cancer 2019 NCI 5F30CA206291-04 Towards the automation of MR spectroscopic imaging in patients with glioblashoma GURBANI, SAUMYA EMORY UNIVERSITY GA $50,016
Brain Cancer 2019 NCI 5R21CA216768-02 Selectively Targeting a PI3K subunit to overcome temozolomide resistance and treat recurrent glioblastoma SHENG, ZHI VIRGINIA POLYTECHNIC INST AND ST UNIV VA $162,004
Brain Cancer 2019 NEI 1R01EY029687-01 Biomarkers of Vision Loss in Children with Optic Pathway Gliomas AVERY, ROBERT CHILDREN'S HOSP OF PHILADELPHIA PA $686,771
Brain Cancer 2019 NCI 5F32CA224593-02 Cancer Immunotherapy Through Intratumoral Activation of Recall Responses BROWN, MICHAEL DUKE UNIVERSITY NC $61,610
Brain Cancer 2019 NINDS 5K08NS101091-03 Characterization of a microRNA network regulating glioblastoma epigenetics, cell reprogramming and DNA repair PERUZZI, PIER PAOLO BRIGHAM AND WOMEN'S HOSPITAL MA $198,400
Brain Cancer 2019 NCI 5R13CA086959-18 The Annual Blood Brain Barrier Consortium Meeting NEUWELT, EDWARD OREGON HEALTH & SCIENCE UNIVERSITY OR $5,000
Brain Cancer 2019 NIDCD 5R13CA086959-18 The Annual Blood Brain Barrier Consortium Meeting NEUWELT, EDWARD OREGON HEALTH & SCIENCE UNIVERSITY OR $5,000
Brain Cancer 2019 NINDS 5R13CA086959-18 The Annual Blood Brain Barrier Consortium Meeting NEUWELT, EDWARD OREGON HEALTH & SCIENCE UNIVERSITY OR $5,000
Brain Cancer 2019 NCI 5R00CA194269-04 Multifunctional, GBM-Activatable Nanocarriers For Image-Guided Photochemotherapy HUANG, HUANG-CHIAO UNIV OF MARYLAND, COLLEGE PARK MD $249,000
Brain Cancer 2019 NIGMS 5P20GM109035-04 6004 Project 2: Integrative Genomics of Cancer Survival HUANG, YEN-TSUNG BROWN UNIVERSITY RI $242,390
Brain Cancer 2019 NIDCD 5F31DC016528-02 A Novel Approach to Treating Sensorineural Hearing loss and Inner Ear Disease in Neurofibromatosis Type 2 (NF2) HAWLEY, ERIC INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS IN $6,506
Brain Cancer 2019 NCI 5R01CA195532-05 Investigating the cytomegalovirus link to glioblastoma using a novel mouse model CHIOCCA, E. BRIGHAM AND WOMEN'S HOSPITAL MA $366,140
Brain Cancer 2019 NCI 5R01CA218859-02 RhoA and GPCR mediated transcriptional activation regulates glioblastoma BROWN, JOAN UNIVERSITY OF CALIFORNIA, SAN DIEGO CA $371,309
Brain Cancer 2019 NCI 1R21CA233856-01 Pilot randomized neoadjuvant vaccine with CD27-costimulation in low-grade glioma OKADA, HIDEHO UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $144,165
Brain Cancer 2019 NCI 5R01CA214066-03 Mechanism-based drug repurposing and novel treatments for glioblastoma NOBLE, MARK UNIVERSITY OF ROCHESTER NY $341,706
Brain Cancer 2019 NCI 1K99CA234434-01 A molecular informed therapy for Diffuse Intrinsic Pontine Gliomas (DIPG) PIUNTI, ANDREA NORTHWESTERN UNIVERSITY AT CHICAGO IL $114,370
Brain Cancer 2019 NCI 1K08CA234416-01 De Novo Nucleotide Synthesis as a Mediator of Radiation Resistance and a Therapeutic Target in Glioblastoma WAHL, DANIEL UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $256,400
Brain Cancer 2019 NINDS 5R01NS100950-02 DEVELOP A NOVEL REPROGRAMMING APPROACH FOR GLIOBLASTOMA MULTIFORME TREATMENT YANG, QIN WASHINGTON UNIVERSITY MO $333,594
Brain Cancer 2019 NINDS 5R01NS100967-03 Mechanisms of RIOK2 function in glioblastoma READ, RENEE EMORY UNIVERSITY GA $338,291
Brain Cancer 2019 NCI 5R01CA216855-02 A novel microfluidic device to predict brain cancer prognosis and response to therapy QUINONES-HINOJOSA, ALFREDO MAYO CLINIC JACKSONVILLE FL $465,567
Brain Cancer 2019 NCI 5R01CA217820-02 Co-targeting mTOR and YAP signaling in glioblastoma GERA, JOSEPH BRENTWOOD BIOMEDICAL RESEARCH INSTITUTE CA $311,041
Brain Cancer 2019 NCI 5R01CA227687-02 The Impact of FUS-Mediated Brain Cancer Therapy on BBB Transport, Cytokines, and Immunocyte Trafficking BUTTS-PAULY, KIM STANFORD UNIVERSITY CA $612,310
Brain Cancer 2019 NCI 1R15CA227680-01A1 Acid-Sensitive Glioblastoma Prodrugs Derived from Ophiobolin A KORNIENKO, ALEXANDER TEXAS STATE UNIVERSITY TX $461,764
Brain Cancer 2019 NINDS 5R01NS096606-04 Connectomics meets neuro-oncology: mapping the brain for treatment planning VERMA, RAGINI UNIVERSITY OF PENNSYLVANIA PA $511,202
Brain Cancer 2019 NINDS 5R01NS086853-05 Role of a Novel TROY-EGFR Complex in Gliobastoma Invasion and Resistance LOFTUS, JOSEPH MAYO CLINIC ARIZONA AZ $385,001
Brain Cancer 2019 NINDS 1R21NS109687-01 Targeting Prostaglandin Receptor EP2 for Glioma and Associated Epilepsy JIANG, JIANXIONG UNIVERSITY OF TENNESSEE HEALTH SCI CTR TN $190,000
Brain Cancer 2019 NINDS 1R21NS109770-01 Impact of radiation-induced senescence on the glioblastoma microenvironment BURNS, TERRY MAYO CLINIC ROCHESTER MN $239,262
Brain Cancer 2019 NCI 5R01CA208851-03 STAT3, G6PD and TrxR as underlying mechanisms for antitumor responses to hirsutinolides TURKSON, JAMES UNIVERSITY OF HAWAII AT MANOA HI $610,274
Brain Cancer 2019 NINDS 5R01NS096368-04 Regulation of Medulloblastoma Metastasis by Emp1 WECHSLER-REYA, ROBERT SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE CA $426,563
Brain Cancer 2019 NINDS 5R01NS096754-03 Chromatin Modifications in GBM-Propagating Cells LATERRA, JOHN HUGO W. MOSER RES INST KENNEDY KRIEGER MD $484,224
Brain Cancer 2019 NIMH 1R21MH118619-01 Maternal brain-TNF as an environmental sensor in programming offspring anxiety TOTH, MIKLOS WEILL MEDICAL COLL OF CORNELL UNIV NY $253,327
Brain Cancer 2019 NCI 5R01CA200399-04 Intra-Operative, Label-Free Detection of Brain Cancer Infiltration with Quantitative Optical Imaging LI, XINGDE JOHNS HOPKINS UNIVERSITY MD $589,760
Brain Cancer 2019 NCI 5R01CA208669-03 A Unique Class of Reductively Activated Oncology Drugs BOGER, DALE SCRIPPS RESEARCH INSTITUTE CA $697,415
Brain Cancer 2019 NINDS 5R01NS095642-04 Radiation + Temozolomide Induced Mutation and Malignant Progression of GBM JAMES, CHARLES NORTHWESTERN UNIVERSITY AT CHICAGO IL $337,969
Brain Cancer 2019 NINDS 7R01NS104315-02 Therapeutic modulation of the phagocytosis axis as a novel glioblastoma immunotherapy KIM, YON SON BETTY UNIVERSITY OF TX MD ANDERSON CAN CTR TX $346,290
Brain Cancer 2019 NCI 5P01CA013106-47 5083 Project 2: Regulation of Pre-mRNA Splicing in Tumorigenesis KRAINER, ADRIAN COLD SPRING HARBOR LABORATORY NY $648,714
Brain Cancer 2019 NCI 1R21CA226483-01A1 A 3D ex vivo orthotopic xenograft screening platform to identify radiosensitization targets and druggability in glioma FLOYD, SCOTT DUKE UNIVERSITY NC $209,561
Brain Cancer 2019 NCI 5F32CA216996-02 Tissue Factor/Protease-Activated Receptor 2 in IDH1 wild-type and IDH1 mutant gliomas UNRUH, DUSTEN NORTHWESTERN UNIVERSITY AT CHICAGO IL $63,746
Brain Cancer 2019 NCI 5R01CA212638-03 QUANTITATIVE DUAL-ENERGY CT IMAGING FOR CANCER IMAGING AND RADIATION THERAPY APPLICATIONS O'SULLIVAN, JOSEPH WASHINGTON UNIVERSITY MO $449,002
Brain Cancer 2019 NCI 1R01CA223370-01A1 Targeting oncogenic dopamine receptor signaling in glioblastoma LEE, JEONGWU CLEVELAND CLINIC LERNER COM-CWRU OH $478,299
Brain Cancer 2019 NCI 5R01CA197488-04 Biomimetic hydrogel niches to study the malignant phenotype of glioblastoma multiforme HARLEY, BRENDAN UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN IL $347,770
Brain Cancer 2019 NCI 5R01CA204720-04 In vivo imaging of the stem cell loaded oncolytic viruses for cancer therapy SHAH, KHALID BRIGHAM AND WOMEN'S HOSPITAL MA $374,748
Brain Cancer 2019 NCI 5R01CA188743-05 Differential MRI imaging for brain tumor metastases diagnosis and treatment monitoring LJUBIMOVA, JULIA CEDARS-SINAI MEDICAL CENTER CA $479,493
Brain Cancer 2019 NIBIB 5R01EB024525-02 Proton Relaxation and Exchange Contrast in MRI GORE, JOHN VANDERBILT UNIVERSITY MEDICAL CENTER TN $405,554
Brain Cancer 2019 NCI 1R15CA235749-01 Target PDE4D to inhibit the Hedgehog pathway GE, XUECAI UNIVERSITY OF CALIFORNIA, MERCED CA $430,288
Brain Cancer 2019 NCI 5F30CA216970-02 Improving CNS Delivery of Chemotherapeutic to Invasive Brain Cancer ROBERTS, NATHAN UNIVERSITY OF MARYLAND BALTIMORE MD $45,770
Brain Cancer 2019 NCI 5F31CA221061-02 Assessing the Robustness of Radiogenomic Associations using Deep Neural Networks in Glioblastoma Multiforme SMEDLEY, NOVA UNIVERSITY OF CALIFORNIA LOS ANGELES CA $39,107
Brain Cancer 2019 NIGMS 5P20GM113132-04 6070 Project 1: Proteomic approaches to target the PP6-mTORC2 pathway in glioblastoma KETTENBACH, ARMINJA DARTMOUTH COLLEGE NH $309,043
Brain Cancer 2019 NCI 1R03CA235200-01 Advancing Treatment for Pediatric Craniopharyngioma (ATPC); in vivo Tocilizumab Measurement HANKINSON, TODD UNIVERSITY OF COLORADO DENVER CO $77,750
Brain Cancer 2019 NCI 1R03CA227206-01A1 Targeting epigenetic remodeling factors to radiosensitize glioblastoma VENERE, MONICA OHIO STATE UNIVERSITY OH $78,000
Brain Cancer 2019 NCI 3U54CA210190-03S1 5270 Examining cell signaling activity during cell migration via fluorescence lifetime biosensors in Glioblastoma and Pancreatic Ductal Adenocarcinoma ODDE, DAVID UNIVERSITY OF MINNESOTA MN $221,640
Brain Cancer 2019 NCI 5R01CA172845-07 Metabolic Reprogramming in Brain Tumors RONEN, SABRINA UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $621,953
Brain Cancer 2019 NCI 5R01CA204020-05 Role of GAS41 in Human Cancer SHI, XIAOBING VAN ANDEL RESEARCH INSTITUTE MI $421,585
Brain Cancer 2019 NCI 5R03CA227312-02 Elucidation of factors and mechanisms that promote glioblastoma stem cell motility and invasiveness GALILEO, DENI UNIVERSITY OF DELAWARE DE $78,000
Brain Cancer 2019 NCI 5R35CA210100-03 Isolation, characterization and translational development of glioma stem cells PARADA, LUIS SLOAN-KETTERING INST CAN RESEARCH NY $1,045,270
Brain Cancer 2019 NCI 5P01CA062220-24 7591 How does EGFR facilitate the constitutive activation of STAT3 in tumors? STARK, GEORGE CLEVELAND CLINIC LERNER COM-CWRU OH $418,801
Brain Cancer 2019 NIGMS 2R01GM089732-09 Synthesis and Study of Cyclotryptamine and Diketopiperazine Alkaloids MOVASSAGHI, MOHAMMAD MASSACHUSETTS INSTITUTE OF TECHNOLOGY MA $456,265
Brain Cancer 2019 NINDS 1R01NS106229-01A1 Crosstalk between EGFR and TEAD Activity Directs Migration in Human Glioblastoma TSANKOVA, NADEJDA ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI NY $370,781
Brain Cancer 2019 NCI 2R01CA166413-06A1 Mechanisms and Function of Autophagy in Cancer JIANG, XUEJUN SLOAN-KETTERING INST CAN RESEARCH NY $426,550
Brain Cancer 2019 NCI 2R01CA228133-06A1 Gene Delivery Nanoparticles to Treat Glioblastoma GREEN, JORDAN JOHNS HOPKINS UNIVERSITY MD $422,099
Brain Cancer 2019 NCI 2R01CA160762-06A1 Targeting tumorigenic pathways in glioblastoma with oncolytic HSV RABKIN, SAMUEL MASSACHUSETTS GENERAL HOSPITAL MA $395,770
Brain Cancer 2019 NCI 1R01CA227149-01A1 Regulation of Amino-acid Transport in Human Gliomas SONTHEIMER, HARALD VIRGINIA POLYTECHNIC INST AND ST UNIV VA $362,569
Brain Cancer 2019 NCI 2R01CA228188-09A1 Amide Proton Transfer (APT) MRI of Brain Tumors at 3T ZHOU, JINYUAN JOHNS HOPKINS UNIVERSITY MD $403,535
Brain Cancer 2019 NCI 2R01CA114567-11A1 Targeted Therapy in Ex Vivo Medulloblastoma/PNET OLSON, JAMES FRED HUTCHINSON CANCER RESEARCH CENTER WA $438,710
Brain Cancer 2019 NCI 1R01CA227874-01A1 Defining the molecular mechanisms regulating the hexosamine-N-glycosylation pathway in glioblastoma GUO, DELIANG OHIO STATE UNIVERSITY OH $312,000
Brain Cancer 2019 NINDS 1R01NS109911-01 Reorienting the Glioblastoma Microenvironment to Respond to Immunotherapy BARCELLOS-HOFF, MARY UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $594,636
Brain Cancer 2019 NCI 5R01CA184090-05 Functional Inhibition of Deubiquitylase HAUSP to Disrupt Glioblastoma Stem Cells BAO, SHIDENG CLEVELAND CLINIC LERNER COM-CWRU OH $351,691
Brain Cancer 2019 NCI 5R01CA196851-04 Targeting vismodegib-resistant tumors using BH3 mimetics KIM, JAMES UT SOUTHWESTERN MEDICAL CENTER TX $336,575
Brain Cancer 2019 NCI 1R21CA226607-01A1 Leveraging MR-Guided Focused Ultrasound to Potentiate Immunotherapy for GBM BULLOCK, TIMOTHY UNIVERSITY OF VIRGINIA VA $173,754
Brain Cancer 2019 NCI 5R01CA116020-13 Inhibitor-sensitive and -resistant EGFR mutants from lung cancer and glioblastoma ECK, MICHAEL DANA-FARBER CANCER INST MA $362,840
Brain Cancer 2019 NCI 5R01CA201327-05 Epigenetic Modulation of Wnt/Beta-catenin Pathway and Tumorigenesis of Glioma Cells by KDM4C HUANG, SUYUN VIRGINIA COMMONWEALTH UNIVERSITY VA $335,746
Brain Cancer 2019 NCI 5U54CA225088-02 5114 Project 2: Measuring and modeling the tumor and immune microenvironment before andduring therapy and at the time of drug resistance SHARPE, ARLENE HARVARD MEDICAL SCHOOL MA $324,561
Brain Cancer 2019 NCI 5R01CA202634-04 Novel functions of D-type and E-type cyclins in normal and in cancer cells SICINSKI, PETER DANA-FARBER CANCER INST MA $418,111
Brain Cancer 2019 NCI 5F30CA217065-04 Epigenetic Regulation of Lipid Metabolism in Glioma Stem Cells GIMPLE, RYAN CASE WESTERN RESERVE UNIVERSITY OH $50,016
Brain Cancer 2019 NINDS 5K08NS091527-04 Tumor DNA in CSF and novel modeling decode breast cancer - brain metastases HAYDEN, MELANIE STANFORD UNIVERSITY CA $185,620
Brain Cancer 2019 NINDS 5R21NS102802-02 Ying Yang 1, a master regulator of chronic inflammation in glioblastoma multiforme KORDULA, TOMASZ VIRGINIA COMMONWEALTH UNIVERSITY VA $232,750
Brain Cancer 2019 NINDS 5R01NS092641-04 Selective Targeting of Glioma Stem Cells Through Sema3C/PlexinD1 YU, JENNIFER CLEVELAND CLINIC LERNER COM-CWRU OH $346,719
Brain Cancer 2019 NLM 1K99LM012874-01A1 Novel Informatics Techniques for Modeling and Analyzing Brain Structure for Facilitating Diagnosis of Neurological Diseases ZHANG, MIN BRIGHAM AND WOMEN'S HOSPITAL MA $89,675
Brain Cancer 2019 NCI 5R01CA192176-04 Developmental studies to inform clinical stratification and targeting of SHH MB JOYNER, ALEXANDRA SLOAN-KETTERING INST CAN RESEARCH NY $452,783
Brain Cancer 2019 NCI 1R01CA235612-01 Clinical Brain Tumor Development of a Cytomegalovirus-targeted Therapeutic with Vaccine pre-conditioning to Validate Novel Predictors of Vaccine Efficacy SAMPSON, JOHN DUKE UNIVERSITY NC $413,970
Brain Cancer 2019 NCI 5R01CA227821-02 Targeting Nicotinamide Adenine Dinucleotide (NAD+) metabolism in IDH mutant gliomas CAHILL, DANIEL MASSACHUSETTS GENERAL HOSPITAL MA $465,738
Brain Cancer 2019 NINDS 5R01NS096238-04 Quantifying Differences in mTOR Activity and Tumor Development Between Neural Stem Cell Microdomains IHRIE, REBECCA VANDERBILT UNIVERSITY TN $335,513
Brain Cancer 2019 NINDS 5F31NS101771-03 The immunosuppressive role of glioblastoma-derived macrophage migration inhibitor factor ALBAN, TYLER CLEVELAND CLINIC LERNER COM-CWRU OH $35,542
Brain Cancer 2019 NCI 5R01CA177810-05 Modulation of MicroRNAs with Xenobiotics to Target c-Myc LI, YONG CLEVELAND CLINIC LERNER COM-CWRU OH $351,691
Brain Cancer 2019 NCI 5R01CA215072-02 Developing miR-10b targeting for glioblastoma KRICHEVSKY, ANNA BRIGHAM AND WOMEN'S HOSPITAL MA $396,616
Brain Cancer 2019 NCI 5R01CA197402-04 Study of exposures and biomarkers in cancer epidemiology SATAGOPAN, JAYA SLOAN-KETTERING INST CAN RESEARCH NY $402,263
Brain Cancer 2019 NCI 1R01CA235673-01 Characterization of Onalespib, A novel long acting Hsp90 inhibitor, as a chemo and radiosensitizer in Adults with Newly Diagnosed Glioblastoma PUDUVALLI, VINAY OHIO STATE UNIVERSITY OH $603,390
Brain Cancer 2019 NCI 5R01CA140316-09 The Role of IDH1 Mutations in Gliomagenesis and Metabolism YAN, HAI DUKE UNIVERSITY NC $366,296
Brain Cancer 2019 NCI 5R01CA202911-04 7T Neurosurgical Mapping Protocol for Endoscopic Resection of Skull Base Tumors BALCHANDANI, PRITI ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI NY $376,098
Brain Cancer 2019 NIGMS 5SC3GM121230-02 The Role of TRPM7 in Progression of Malignant Glioma LIU, MINGLI MOREHOUSE SCHOOL OF MEDICINE GA $106,500
Brain Cancer 2019 NINDS 1R21NS106537-01A1 Targeting cell polarity to disrupt the interaction of glioblastomas with the neural environment VIAPIANO, MARIANO UPSTATE MEDICAL UNIVERSITY NY $243,000
Brain Cancer 2019 NCI 1R21CA226562-01A1 Ultra-high-dose-rate proton therapy for malignant glioma ELEY, JOHN VANDERBILT UNIVERSITY MEDICAL CENTER TN $235,684
Brain Cancer 2019 NINDS 1R21NS104454-01A1 GALV-Based Retroviral Replicating Vectors for Glioma Gene Therapy KASAHARA, NORIYUKI UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $401,456
Brain Cancer 2019 NINDS 5F31NS101750-03 Rescuing neurogenesis after irradiation: radial glial cells and a role for bone morphogenic protein inhibitors BELCHER, ELIZABETH UNIVERSITY OF ROCHESTER NY $23,254
Brain Cancer 2019 NCI 5R01CA150153-10 Enhancing viral oncolysis with vasculostatin gene delivery KAUR, BALVEEN UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON TX $362,675
Brain Cancer 2019 NCI 5R01CA204968-04 Targeted Delivery of Brain Penetrating DNA Nanoparticles to Brain Tumors HANES, JUSTIN JOHNS HOPKINS UNIVERSITY MD $488,981
Brain Cancer 2019 NCI 5K01CA226346-02 Understanding mechanistic role of SAMHD1 in DNA damage response and therapeutic benefit for malignant glioma DADDACHA, WAAQO EMORY UNIVERSITY GA $109,734
Brain Cancer 2019 NINDS 5R01NS064983-10 Glioblastoma stem cells therapy TANNOUS, BAKHOS MASSACHUSETTS GENERAL HOSPITAL MA $388,606
Brain Cancer 2019 NCI 1R01CA231513-01A1 Development and Dissemination of Clinical CEST MRI Acquisition and Analysis Methods for Cancer Imaging Applications PAGEL, MARK "MARTY" UNIVERSITY OF TX MD ANDERSON CAN CTR TX $652,625
Brain Cancer 2019 NCI 5R01CA216054-03 (PQ1) Identifying and targeting human glioblastoma migrating in the peritumoral niche HAYDEN, MELANIE STANFORD UNIVERSITY CA $348,904
Brain Cancer 2019 NCI 5R01CA215489-03 MYB family alterations in pediatric gliomas LIGON, KEITH DANA-FARBER CANCER INST MA $537,868
Brain Cancer 2019 NIBIB 5R01EB020683-04 Quantitative Image Modeling for Brain Tumor Analysis and Tracking IFTEKHARUDDIN, KHAN OLD DOMINION UNIVERSITY VA $400,000
Brain Cancer 2019 NINDS 5R00NS089780-05 Identification of transcription factors that regulate astrocyte differentiation ZHANG, YE UNIVERSITY OF CALIFORNIA LOS ANGELES CA $248,142
Brain Cancer 2019 NINDS 5F31NS106887-02 The Role of IL-1 in Glioblastoma-Associated Angiogenesis and Tumor Progression HERTING, CAMERON EMORY UNIVERSITY GA $45,016
Brain Cancer 2019 NCI 5R01CA206190-04 Treatment of glioma with nanocombretastatin with MRI monitoring ALI, MESER HENRY FORD HEALTH SYSTEM MI $333,940
Brain Cancer 2019 NCI 5R01CA216354-03 Late Effects Prediction using Clinical Phenotypes and Whole Genome Sequencing YASUI, YUTAKA ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $728,864
Brain Cancer 2019 NCI 5R01CA188228-05 Genetic evolution of glioblastomas during radiation and temozolomide therapy BEROUKHIM, RAMEEN DANA-FARBER CANCER INST MA $656,695
Brain Cancer 2019 NCI 5R01CA184476-05 Molecular and Therapeutic Basis of Morphometric Aberrations in Brain Tumors CHANG, HANG UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB CA $385,191
Brain Cancer 2019 NCI 5R01CA197254-04 Metabolic Imaging of Brain Tumor Response to Therapy RONEN, SABRINA UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $637,111
Brain Cancer 2019 NCI 5R01CA155769-08 Role of Receptor for Advanced Glycation End Product (RAGE) Pathway in Brain Tumors BADIE, BEHNAM BECKMAN RESEARCH INSTITUTE/CITY OF HOPE CA $413,174
Brain Cancer 2019 NCI 5P30CA013148-47 8603 04 Neuro-Oncology Program GILLESPIE, G. UNIVERSITY OF ALABAMA AT BIRMINGHAM AL $116,289
Brain Cancer 2019 NCI 5R01CA199111-35 Opening of the Blood-Brain Barrier to Antitumor Agents NEUWELT, EDWARD OREGON HEALTH & SCIENCE UNIVERSITY OR $598,661
Brain Cancer 2019 NCI 5R01CA190891-05 The role of the LZTR1 ubiquitin ligase in stem cells and cancer IAVARONE, ANTONIO COLUMBIA UNIVERSITY HEALTH SCIENCES NY $371,586
Brain Cancer 2019 NCI 5R01CA203388-03 2D MR Correlational Spectroscopy Platform for Molecular and Genetic Characterizations of Glioma MAO, HUI EMORY UNIVERSITY GA $420,865
Brain Cancer 2019 NINDS 5R01NS105556-02 Interactions between the tumor cells and the neuro-immune microenvironment in mutant IDH1 gliomas: implications for therapeutics CASTRO, MARIA UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $456,274
Brain Cancer 2019 NIBIB 1R21EB027506-01 Focal ultrasound-mediated nonthermal ablation of brain tumors PORTER, TYRONE BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) MA $269,662
Brain Cancer 2019 NCI 5R01CA204723-03 Development of PET imaging biomarkers to predict enhanced glioblastoma radiotherapy by a novel H-NOX oxygen carrier KRTOLICA, ANA OMNIOX, INC. CA $546,766
Brain Cancer 2019 NINDS 1R41NS110296-01 Glioblastoma multiforme therapy via telomerase reverse transcriptase (hTERT) down-regulation. Molecular chaperones redirect quadruplex folding to reverse the effect of hTERT gene promoter mutations. HURLEY, LAURENCE REGLAGENE, LLC AZ $401,714
Brain Cancer 2019 NCI 1F31CA236175-01 Irreversible Inhibtion of Cerebellar Gli Transcription Factors by Cobalt (III) Complexes WARD, MEGHAN NORTHWESTERN UNIVERSITY IL $39,840
Brain Cancer 2019 NCATS 2R42TR001789-02A1 Personalized Neural Stem Cell Therapy for Cancer NICHOLS, SUSAN FALCON THERAPEUTICS, INC. NC $716,643
Brain Cancer 2019 NINDS 7R01NS097649-03 Targeting Mechanisms of Acquired Temozolomide Resistance in Glioblastoma CHEN, CLARK UNIVERSITY OF MINNESOTA MN $336,875
Brain Cancer 2019 NCI 5F32CA224962-02 Dissecting the Molecular Mechanisms of Stem Cell Niche Invasion and Radiotherapy Resistance in Glioblastoma MISTRY, AKSHITKUMAR VANDERBILT UNIVERSITY MEDICAL CENTER TN $19,645
Brain Cancer 2019 NCI 5R21CA226301-02 Collateral Deletions Expose Targetable Metabolic Vulnerabilities in the PTEN locus MULLER, FLORIAN UNIVERSITY OF TX MD ANDERSON CAN CTR TX $168,779
Brain Cancer 2019 NINDS 5R01NS080939-07 Genotypic Interactions in Brain Cancer Heterogeneity FURNARI, FRANK LUDWIG INSTITUTE FOR CANCER RES LTD CA $350,000
Brain Cancer 2019 NCI 5R01CA218596-02 MRI Signatures of Response to High-Dose Radiotherapy in Rat Models of Cerebral Tumor EWING, JAMES HENRY FORD HEALTH SYSTEM MI $472,680
Brain Cancer 2019 NCI 1F32CA236462-01 Investigating the role of SPRY2 in regulating drug resistance of GBM tumors and interactions between GBM tumor cells and macrophages SOSALE, NISHA UNIVERSITY OF VIRGINIA VA $65,606
Brain Cancer 2019 NLM 1F31LM013056-01 Transfer learning approaches for integration of single cell RNA sequencing data from multiple sources JOHNSON, TRAVIS OHIO STATE UNIVERSITY OH $33,283
Brain Cancer 2019 NCI 1F31CA228207-01A1 The Study of Immune Effects in Gliomas Treated with Oncolytic Viruses in Combination with IDO Inhibitors NGUYEN, TERESA UNIVERSITY OF TX MD ANDERSON CAN CTR TX $32,506
Brain Cancer 2019 NCI 1F32CA236432-01 Epigenetic Induction of Gliomagenesis in Neural Progenitor Cells RAHME, GILBERT MASSACHUSETTS GENERAL HOSPITAL MA $61,226
Brain Cancer 2019 NCI 1U01CA236489-01 Developing a Translation Pipeline for VHL Mutant Malignancies MCDERMOTT, DAVID BETH ISRAEL DEACONESS MEDICAL CENTER MA $649,803
Brain Cancer 2019 NCI 1U01CA236215-01 Chemoprotection & Immune Remodeling after Hematopoietic Progenitor Cell Gene Therapy for Glioblastoma SLOAN, ANDREW CASE WESTERN RESERVE UNIVERSITY OH $565,191
Brain Cancer 2019 NCI 5F30CA228280-02 Engineering RNA-nanoparticles to enhance dendritic cell mediated treatment of glioblastoma GRIPPIN, ADAM UNIVERSITY OF FLORIDA FL $49,755
Brain Cancer 2019 NCI 5R01CA188359-05 Lassa-VSV targets and kills glioma, and is not neurotoxic VAN DEN POL, ANTHONY YALE UNIVERSITY CT $316,592
Brain Cancer 2019 NCI 2R13CA124293-12 Annual International Primary CNS Lymphoma Collaborative Group Meeting BATCHELOR, TRACY MASSACHUSETTS GENERAL HOSPITAL MA $5,000
Brain Cancer 2019 NCI 5F30CA225143-02 Metabolic Resistance to Hypoxia in Glioblastoma Multiforme CAFLISCH, LAURA UNIVERSITY OF TEXAS HLTH SCIENCE CENTER TX $33,404
Brain Cancer 2019 NCI 1R01CA236500-01 Clinical evaluation of IL13Ra2-targeted CAR T cell therapy in combination with nivolumab in patients with recurrent malignant glioma BROWN, CHRISTINE BECKMAN RESEARCH INSTITUTE/CITY OF HOPE CA $665,839
Brain Cancer 2019 NCI 5P30CA006973-56 8091 Brain Cancer Program - 09 GROSSMAN, STUART JOHNS HOPKINS UNIVERSITY MD $55,386
Brain Cancer 2019 NCI 5R01CA214557-03 Spectroscopic MRI to guide radiation dose escalation for glioblastoma patients SHIM, HYUNSUK EMORY UNIVERSITY GA $138,906
Brain Cancer 2019 NINDS 5R01NS099207-03 Improving the Safety and Efficacy of Intraventricular Neurosurgery via Robotics DUPONT, PIERRE BOSTON CHILDREN'S HOSPITAL MA $472,005
Brain Cancer 2019 NCI 5R01CA204297-03 The epigenetic mechanisms of high-grade pediatric glioblastoma ZHANG, ZHIGUO COLUMBIA UNIVERSITY HEALTH SCIENCES NY $475,345
Brain Cancer 2019 NCI 5R01CA215453-03 Exploiting Mutant IDH1/2-induced Homologous Recombination Defects in Cancer BINDRA, RANJIT YALE UNIVERSITY CT $374,228
Brain Cancer 2019 NCI 5F31CA228317-02 A 3D Model of the Perivascular Niche to Investigate Glioblastoma Invasion WOLF, KAYLA UNIVERSITY OF CALIFORNIA BERKELEY CA $33,991
Brain Cancer 2019 NCI 5P30CA033572-36 5262 Cancer Immunotherapeutics LEE, PETER BECKMAN RESEARCH INSTITUTE/CITY OF HOPE CA $59,314
Brain Cancer 2019 NINDS 5F31NS101883-02 Cooperation of BCL-xL and SHH in regulating cell survival during cerebellar neurogenesis and in medulloblastoma VELETA, KATHERINE UNIV OF NORTH CAROLINA CHAPEL HILL NC $28,492
Brain Cancer 2019 NIGMS 5R01GM119011-04 Regulation of Centromere Protein Stability and Impact on Cancer Progression KARPEN, GARY UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB CA $527,205
Brain Cancer 2019 NCI 5R01CA206220-04 Nanoconjugate delivery of proliferation and checkpoint inhibitors to treat glial tumors LJUBIMOVA, JULIA CEDARS-SINAI MEDICAL CENTER CA $541,408
Brain Cancer 2019 NIBIB 5P41EB015891-25 6691 Project-005 GLOVER, GARY STANFORD UNIVERSITY CA $278,514
Brain Cancer 2019 NCI 5R01CA209921-04 Glial tumor image-guided surgery and treatment HOLLER, EGGEHARD CEDARS-SINAI MEDICAL CENTER CA $495,835
Brain Cancer 2019 NCI 5P30CA042014-30 5855 Cell Response and Regulation Program (Project-002) WELM, ALANA UNIVERSITY OF UTAH UT $51,416
Brain Cancer 2019 NINDS 5R01NS091219-05 Targeting Wee1 in Myc driven Medulloblasoma VIBHAKAR, RAJEEV UNIVERSITY OF COLORADO DENVER CO $255,118
Brain Cancer 2019 NINDS 5R01NS095817-04 Systemic gene therapy for glioblastoma ZHOU, JIANGBING YALE UNIVERSITY CT $364,219
Brain Cancer 2019 NCI 5R01CA197313-04 Functional Dissection of the K27M Histone Mutation In Gliomagenesis BECHER, OREN NORTHWESTERN UNIVERSITY AT CHICAGO IL $4,014
Brain Cancer 2019 NINDS 5R01NS092597-04 Neuronal activity-regulated mechanisms of glioma growth MONJE-DEISSEROTH, MICHELLE STANFORD UNIVERSITY CA $345,030
Brain Cancer 2019 NINDS 5R01NS094615-04 Modeling malignant progression in glioma RAO, GANESH UNIVERSITY OF TX MD ANDERSON CAN CTR TX $350,000
Brain Cancer 2019 NINDS 5R01NS094670-04 Regulation of Glioblastoma Stem-Like Cells by CDC20-Anaphase-Promoting Complex KIM, ALBERT WASHINGTON UNIVERSITY MO $333,594
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