Skip Navigation
 

Funding


RCDC

Project Listing by Category


Back to Estimates of Funding for Various Research, Condition, and Disease Categories (RCDC) Click the column headings to sort project listings.
  Help
CategoryFYFunding ICProject NumberSub Project #Project TitlePI NameOrg NameState / CountryAmount
ALS 2019 NINDS 5R01NS100023-05 Deconstructing the cellular and molecular basis of SBMA motor neuron disease: From mechanism to therapy LA SPADA, ALBERT DUKE UNIVERSITY NC $494,845
ALS 2019 NIA 5R01NS095969-04 TDP-43 Proteinopathy in ALS-FTD: Mechanism, Target Validation and Biomarker WONG, PHILIP JOHNS HOPKINS UNIVERSITY MD $50,625
ALS 2019 NINDS 5R01NS095969-04 TDP-43 Proteinopathy in ALS-FTD: Mechanism, Target Validation and Biomarker WONG, PHILIP JOHNS HOPKINS UNIVERSITY MD $354,375
ALS 2019 NIA 5R01NS098243-03 Mechanistic studies and therapeutics for ALS-FTD linked to UBQLN2 mutations MONTEIRO, MERVYN UNIVERSITY OF MARYLAND BALTIMORE MD $88,266
ALS 2019 NINDS 5R01NS098243-03 Mechanistic studies and therapeutics for ALS-FTD linked to UBQLN2 mutations MONTEIRO, MERVYN UNIVERSITY OF MARYLAND BALTIMORE MD $416,115
ALS 2019 NINDS 5R01NS091748-06 Loss of siRNA based gene silencing and retrotransposon activation in TDP-43 mediated neurodegeneration DUBNAU, JOSHUA STATE UNIVERSITY NEW YORK STONY BROOK NY $347,660
ALS 2019 NINDS 5R01NS062055-10 Mitochondria quality control in SOD1-ALS MANFREDI, GIOVANNI WEILL MEDICAL COLL OF CORNELL UNIV NY $370,781
ALS 2019 NINDS 5R35NS097275-03 Molecular Genetic Insight into Neurodegenerative Disease from Drosophila BONINI, NANCY UNIVERSITY OF PENNSYLVANIA PA $703,113
ALS 2019 NINDS 5R35NS097263-03 Innovating Yeast and Human Genetics Approaches to Define Mechanisms of Neurodegenerative Disease GITLER, AARON STANFORD UNIVERSITY CA $1,027,273
ALS 2019 NINDS 5F30NS100217-03 Mechanisms Underlying the Pathogenic Role of an α-Adducin/α2-Na/K ATPase Complex in Amyotrophic Lateral Sclerosis SMITH, SARAH WASHINGTON UNIVERSITY MO $50,016
ALS 2019 NINDS 5R35NS097974-03 Dynamic RNA-protein assemblies and neurological disease TAYLOR, JOSEPH ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $897,500
ALS 2019 NINDS 5R01NS073829-09 Study on Neurodegeneration using TDP-43 Transgenic Rats ZHOU, HONGXIA UNIVERSITY OF CENTRAL FLORIDA FL $314,775
ALS 2019 NINDS 5R21NS099545-02 The impact of mitochondrial Ca2+ uptake in skeletal muscle in ALS pathogenesis WEI-LAPIERRE, LAN UNIVERSITY OF ROCHESTER NY $231,000
ALS 2019 NINDS 5R35NS097261-03 Genetic Discovery and Pathobiology of Frontotemporal Lobar Degeneration and Related TDP-43 Proteinopathies RADEMAKERS, ROSA MAYO CLINIC JACKSONVILLE FL $1,002,684
ALS 2019 NIA 5R01NS095793-04 Epigenetic Editing of Mutant C9orf72 LEE, EDWARD UNIVERSITY OF PENNSYLVANIA PA $50,000
ALS 2019 NINDS 5R01NS095793-04 Epigenetic Editing of Mutant C9orf72 LEE, EDWARD UNIVERSITY OF PENNSYLVANIA PA $423,444
ALS 2019 NINDS 5R01NS100835-03 NGF and RAGE-p75NTR signaling in models of amyotrophic lateral sclerosis PEHAR, MARIANA MEDICAL UNIVERSITY OF SOUTH CAROLINA SC $327,031
ALS 2019 NINDS 5R01NS095972-04 Study Neurodegeneration Using Rat Models HUANG, CAO THOMAS JEFFERSON UNIVERSITY PA $341,250
ALS 2019 NINDS 5R01NS091836-05 Mechanisms Underlying Excitability Regulation of Motoneuron Types in ALS ELBASIOUNY, SHERIF WRIGHT STATE UNIVERSITY OH $388,278
ALS 2019 NINDS 5R37NS057553-13 Investigating Pathogenic Mechanisms of Frontotemporal Dementia Caused by Mutations in CHMP2B and TBK1 GAO, FEN-BIAO UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $594,625
ALS 2019 NINDS 5R21NS102556-02 Developing human regulatory T cells that are engineered to target mutant SOD1 SENTMAN, CHARLES DARTMOUTH COLLEGE NH $243,000
ALS 2019 NIEHS 5R01ES024064-05 Environmental Metals, Excitotoxicity and ALS ATCHISON, WILLIAM MICHIGAN STATE UNIVERSITY MI $506,648
ALS 2019 NINDS 5R01NS097679-03 Mitochondrial dynamics for the maintenance of neuromuscular junctions during aging and in ALS WANG, XINGLONG CASE WESTERN RESERVE UNIVERSITY OH $410,577
ALS 2019 NINDS 5R01NS092651-04 Smad Signaling in Skeletal Muscle as a Biomarker of Disease Progression in ALS KING, PETER UNIVERSITY OF ALABAMA AT BIRMINGHAM AL $321,563
ALS 2019 NINDS 5R01NS074324-09 Neurodegeneration and Proteotoxicity Dissected in C. elegans and Mammals WANG, JIOU JOHNS HOPKINS UNIVERSITY MD $364,973
ALS 2019 NIA 5R01NS096785-09 Integrating Quality Control: Studies of UBQLN2 in Age-Related Neurodegeneration PAULSON, HENRY UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $37,432
ALS 2019 NINDS 5R01NS096785-09 Integrating Quality Control: Studies of UBQLN2 in Age-Related Neurodegeneration PAULSON, HENRY UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $642,759
ALS 2019 NINDS 5R01NS095962-04 Study on hnRNPA1 Pathobiology in ALS XIA, XU-GANG UNIVERSITY OF CENTRAL FLORIDA FL $314,775
ALS 2019 NIA 5R01NS104219-02 Determining How Defective Nucleo-Cytoplasmic Trafficking Leads To Neurodegeneration In C9orf72-Related ALS And FTD KISKINIS, EVANGELOS NORTHWESTERN UNIVERSITY AT CHICAGO IL $91,407
ALS 2019 NINDS 5R01NS104219-02 Determining How Defective Nucleo-Cytoplasmic Trafficking Leads To Neurodegeneration In C9orf72-Related ALS And FTD KISKINIS, EVANGELOS NORTHWESTERN UNIVERSITY AT CHICAGO IL $430,935
ALS 2019 NINDS 5R01NS100815-03 Using HTS to Identify Inhibitors of R155H-p97/VCP Mutant to treat IBMPFD/ALS CHOU, TSUI-FEN LA BIOMED RES INST/ HARBOR UCLA MED CTR CA $352,074
ALS 2019 NINDS 5R01NS096746-05 AMPK, metabolism and ALS KALB, ROBERT NORTHWESTERN UNIVERSITY AT CHICAGO IL $459,903
ALS 2019 NIA 1R21NS109755-01 Modifiers of C9orf72 repeat dynamics WHEELER, VANESSA MASSACHUSETTS GENERAL HOSPITAL MA $451,045
ALS 2019 NINDS 5R00NS091486-05 Nucleocentric molecular characterization of C9orf72 NRE-linked neurodegeneration HAEUSLER, AARON THOMAS JEFFERSON UNIVERSITY PA $241,677
ALS 2019 NINDS 5R01NS091540-05 Muscle stem cells: New ALS growth factor therapy and disease model SUZUKI, MASATOSHI UNIVERSITY OF WISCONSIN-MADISON WI $334,688
ALS 2019 NIA 5K01AG049152-05 RNA signatures of frontotemporal dementia and ALS due to C9ORF72 expansion YOKOYAMA, JENNIFER UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $129,600
ALS 2019 NIAMS 1R21AR074746-01 Preclinical Studies in Myopathy and ALS with VCP inhibitor CB5083 KIMONIS, VIRGINIA UNIVERSITY OF CALIFORNIA-IRVINE CA $203,940
ALS 2019 NINDS 5R01NS105756-02 An optogenetic approach to establish the interplay between stress granules and TDP-43 proteinopathy in ALS/FTD DONNELLY, CHRISTOPHER UNIVERSITY OF PITTSBURGH AT PITTSBURGH PA $327,060
ALS 2019 NINDS 5R01NS100859-03 Delineating Physiologic Mechanisms of Swallowing impairment and Decline in ALS PLOWMAN, EMILY UNIVERSITY OF FLORIDA FL $423,295
ALS 2019 NIA 1R01AG058636-01A1 Impeding transcription of expanded microsatellite repeats using deactivated Cas9 WANG, ERIC UNIVERSITY OF FLORIDA FL $378,282
ALS 2019 NIGMS 5R35GM122524-03 RNA Processing Machines in Biology and Disease REED, ROBIN HARVARD MEDICAL SCHOOL MA $645,032
ALS 2019 NINDS 5R01NS090962-05 Re-Establishing Vascular Integrity in ALS via Endothelial Cell Transplant GARBUZOVA-DAVIS, SVITLANA UNIVERSITY OF SOUTH FLORIDA FL $327,031
ALS 2019 NIGMS 2R01GM105718-06 Molecular mechanisms that match lysosome function to cellular demand FERGUSON, SHAWN YALE UNIVERSITY CT $343,375
ALS 2019 NINDS 5F31NS106754-02 Early anatomic markers and genetic risk factors for frontotemporal degeneration in amyotrophic lateral sclerosis PLACEK, KATERINA UNIVERSITY OF PENNSYLVANIA PA $45,016
ALS 2019 NINDS 5R37NS060698-11 Mechanistic analysis of axonal transport defects in neurodegenerative disease HOLZBAUR, ERIKA UNIVERSITY OF PENNSYLVANIA PA $458,300
ALS 2019 NINDS 5R01NS093872-05 Metabolic profiling of sporadic ALS patients: from fibroblasts to neurons and back MANFREDI, GIOVANNI WEILL MEDICAL COLL OF CORNELL UNIV NY $530,987
ALS 2019 NINDS 5R01NS078398-08 Using motor neuron specific miRNA to understand and develop novel therapeutics for motor neuron disease MILLER, TIMOTHY WASHINGTON UNIVERSITY MO $448,083
ALS 2019 NINDS 1R01NS105621-01A1 Preserving mitochondrial function for alleviating ALS progression ZHOU, JINGSONG UNIVERSITY OF TEXAS ARLINGTON TX $583,090
ALS 2019 NIA 5R01NS094239-04 Nucleocytoplasmic transport and nuclear pore disruption in ALS/FTD ROTHSTEIN, JEFFREY JOHNS HOPKINS UNIVERSITY MD $138,521
ALS 2019 NINDS 5R01NS094239-04 Nucleocytoplasmic transport and nuclear pore disruption in ALS/FTD ROTHSTEIN, JEFFREY JOHNS HOPKINS UNIVERSITY MD $514,503
ALS 2019 NIGMS 5R01GM118530-04 Turning off the molecular switch for pathological self-assembly of FUS FAWZI, NICOLAS BROWN UNIVERSITY RI $330,331
ALS 2019 NIDCD 5R01DC014034-05 Advanced neural decoders for the restoration of communication HENDERSON, JAIMIE STANFORD UNIVERSITY CA $683,876
ALS 2019 NIEHS 5R21ES028472-02 Air Pollution Exposure and Risk of Amyotrophic Lateral Sclerosis (ALS) KIOUMOURTZOGLOU, MARIANTHI-ANNA COLUMBIA UNIVERSITY HEALTH SCIENCES NY $180,238
ALS 2019 NCATS 5R44TR002047-03 Commercialization of a Software Platform to Increase the Efficiency of Human Clinical Trials using Patient-Level Machine Learning Models ENNIST, DAVID ORIGENT DATA SCIENCES, INC. VA $513,676
ALS 2019 NINDS 5R01NS089616-05 Investigating disease Mechanisms in C9orf72-linked ALS/FTD WANG, JIOU JOHNS HOPKINS UNIVERSITY MD $354,375
ALS 2019 NIA 5R01NS099371-04 CircRNAs and CNS Gene Transfer ASOKAN, ARAVIND DUKE UNIVERSITY NC $378,326
ALS 2019 NINDS 5R01NS101895-03 An in vivo approach to understanding mutant PFN1 toxicity on motor neurons XU, ZUOSHANG UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $366,406
ALS 2019 NIA 1R01NS110098-01 Mechanisms of RNA and Protein Dysregulations in ALS/FTD Associated with FUS and Ubiquilin 2 WANG, JIOU JOHNS HOPKINS UNIVERSITY MD $543,000
ALS 2019 NIA 5R01NS101986-03 Induced Pluripotent Stem Cells and Drosophila Models of C9ORF72-Related FTD/ALS GAO, FEN-BIAO UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $119,000
ALS 2019 NINDS 5R01NS101986-03 Induced Pluripotent Stem Cells and Drosophila Models of C9ORF72-Related FTD/ALS GAO, FEN-BIAO UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $350,838
ALS 2019 NIGMS 1R43GM128498-01A1 AmplideX DeepNet, a new paradigm for deep learning analytical tools in the molecular diagnostic space LARSON, JESSICA ASURAGEN, INC. TX $223,058
ALS 2019 NINDS 1R43NS110339-01 Development of a human cellular TBK1 model for drug discovery in ALS HINCKLEY, SANDY QURALIS CORPORATION MA $224,119
ALS 2019 NIGMS 1F32GM131668-01 Altered nucleolar phase separation by NPM1 in ALS WHITE, MICHAEL ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $61,610
ALS 2019 NINDS 5R21NS102960-02 The Role of NK Cells in ALS FELDMAN, EVA UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $193,750
ALS 2019 NIA 1RF1AG062077-01 Novel genetic modifiers of C9orf72 and Tau toxicity FRYER, JOHN MAYO CLINIC JACKSONVILLE FL $4,037,235
ALS 2019 NIA 5F32AG059358-02 Determine how loss-of-function of the TBK1 kinase causes age-dependent degeneration in frontotemporal dementia YU, HAIYANG LUDWIG INSTITUTE FOR CANCER RES LTD CA $67,248
ALS 2019 NINDS 5R21NS102599-02 Circadian Timekeeping, Oxidative Stress and Metabolism in ALS Models VARGAS, MARCELO MEDICAL UNIVERSITY OF SOUTH CAROLINA SC $184,355
ALS 2019 NINDS 5R01NS073873-09 Identification of ALS associated genes using whole genome sequencing LANDERS, JOHN UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $441,491
ALS 2019 NIA 5R01NS099320-03 Oligodendroglial Dysfunction in C9orf72 ALS and FTD ROTHSTEIN, JEFFREY JOHNS HOPKINS UNIVERSITY MD $597,360
ALS 2019 NINDS 5R01NS089640-05 NAD metabolsim and mitochondrial dysfunction in ALS models VARGAS, MARCELO MEDICAL UNIVERSITY OF SOUTH CAROLINA SC $327,031
ALS 2019 NINDS 5R01NS091722-04 Molecular phenotyping of cortical cell types in multiple rodent models of ALS SCHMIDT, ERIC ROCKEFELLER UNIVERSITY NY $370,781
ALS 2019 NINDS 5F30NS100595-03 Single-molecule resolution of RNA editing of mRNAs: visualizing GRIA2 editing in situ in ALS MELLIS, IAN UNIVERSITY OF PENNSYLVANIA PA $32,068
ALS 2019 NINDS 5R44NS105156-02 PIKFYVE antagonism as a therapy for C9ORF72-ALS/FTD ALWORTH, SAMUEL ACURASTEM, INC. CA $265,079
ALS 2019 NINDS 5R01NS091299-05 RNA dysregulation in neurodegeneration ZARNESCU, DANIELA UNIVERSITY OF ARIZONA AZ $321,921
ALS 2019 NINDS 5R01NS107479-02 Targeting the EPhA4 in motor neuron disease: a structure-based approach PELLECCHIA, MAURIZIO UNIVERSITY OF CALIFORNIA RIVERSIDE CA $453,229
ALS 2019 NINDS 1R01NS110455-01 Study on PFN1 Pathobiology Using Rat Models XIA, XU-GANG UNIVERSITY OF CENTRAL FLORIDA FL $589,651
ALS 2019 NINDS 5R01NS103777-02 Rad and amyotrophic lateral sclerosis (ALS) BANNISTER, ROGER UNIVERSITY OF COLORADO DENVER CO $340,156
ALS 2019 NINDS 5U01NS107027-02 Multi-Center ALS Biomarker Validation Study (CReATe Biomarkers) BENATAR, MICHAEL UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $729,722
ALS 2019 NIA 5R00AG047335-05 The Role of Cortical Projection Neurons Susceptible to Progressive Degeneration wIth Aging MAROOF, ASIF UNIVERSITY OF TEXAS SAN ANTONIO TX $241,618
ALS 2019 NINDS 5R44NS095481-04 TDP-43 aggregation inhibitors for the treatment of ALS LARSEN, GLENN AQUINNAH PHARMACEUTICALS, INC. MA $2,510,981
ALS 2019 NINDS 5P01NS099114-03 7850 Administrative Core DISNEY, MATTHEW SCRIPPS FLORIDA FL $163,330
ALS 2019 NINDS 5P01NS099114-03 7851 Lead Optimization to Support Cellular and Animal Studies ROUSH, WILLIAM SCRIPPS FLORIDA FL $225,205
ALS 2019 NINDS 5P01NS099114-03 7852 Development of small molecule chemical probes to study r(G4C2)exp pathomechanisms DISNEY, MATTHEW SCRIPPS FLORIDA FL $348,955
ALS 2019 NINDS 5P01NS099114-03 7853 Validation of r(G4C2)exp-binding small molecules in vivo and c9FTD/ALS biomarker development PETRUCELLI, LEONARD MAYO CLINIC JACKSONVILLE FL $348,955
ALS 2019 NINDS 5P01NS099114-03 7854 Mitigation of nuclear pore dysfunction in c9FTD/ALS pathogenesis ROTHSTEIN, JEFFREY JOHNS HOPKINS UNIVERSITY MD $348,955
ALS 2019 NINDS 5R01NS102414-03 CAT-tails: A Novel Type of Protein Modification Implicated in Neurodegeneration COX, GREGORY JACKSON LABORATORY ME $659,497
ALS 2019 NINDS 5R21NS103009-02 Characterization of ATXN2 as a target for ALS in SCA2 motor neurons PULST, STEFAN UNIVERSITY OF UTAH UT $228,750
ALS 2019 NINDS 5R21NS104609-02 Identification of exosome signature in serum from ALS patients BUTOVSKY, OLEG BRIGHAM AND WOMEN'S HOSPITAL MA $242,406
ALS 2019 NINDS 5F31NS100302-03 Determining the role of RNA-based factors in RAN translation of C9ALS/FTD-associated GGGGCC repeats GREEN, KATELYN UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $42,699
ALS 2019 NINDS 5SC2NS104275-03 Determination of cell death pathways activated in ALS YANG, WAN ST. JOHN'S UNIVERSITY NY $164,000
ALS 2019 NIDCD 5R21DC016071-02 Impact of serotonin deficiency on speech and swallow function in a mouse model of Amyotrophic Lateral Sclerosis (ALS) LEVER, TERESA UNIVERSITY OF MISSOURI-COLUMBIA MO $189,753
ALS 2019 NINDS 5R21NS107922-02 Probing the terminal / perisynaptic Schwann cell transcriptome in early stages of motor neuron disease using a RiboTag approach. GOULD, THOMAS UNIVERSITY OF NEVADA RENO NV $178,240
ALS 2019 NINDS 5R21NS106313-02 Analysis of sensory neurons to understand and identify factors to treat ALS VALDEZ, GREGORIO VIRGINIA POLYTECHNIC INST AND ST UNIV VA $39,786
ALS 2019 NIEHS 5K23ES027221-03 Impact of Geospatial Factors and Environmental Pollutants on Amyotrophic Lateral Sclerosis in the State of Michigan GOUTMAN, STEPHEN UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $201,789
ALS 2019 NIA 5R01NS100008-03 Deciphering the role of ER stress in ALS pathogenesis caused by UBQLN2 mutations MONTEIRO, MERVYN UNIVERSITY OF MARYLAND BALTIMORE MD $547,956
ALS 2019 NIA 5R01NS097545-04 Role of C9orf72 in Neurodegeneration BALOH, ROBERT CEDARS-SINAI MEDICAL CENTER CA $54,687
ALS 2019 NINDS 5R01NS097545-04 Role of C9orf72 in Neurodegeneration BALOH, ROBERT CEDARS-SINAI MEDICAL CENTER CA $328,126
ALS 2019 NINDS 5R01NS091110-05 Treatment of ALS based on transplantation of glial restricted progenitors WALCZAK, PIOTR JOHNS HOPKINS UNIVERSITY MD $354,350
ALS 2019 NINDS 5R01NS050452-14 An In Vitro Model of Stem Cell Innervation of Myotubes HICKMAN, JAMES UNIVERSITY OF CENTRAL FLORIDA FL $481,578
ALS 2019 NIGMS 5U01GM117175-03 High-Content Screening to identify small molecules for refolding SOD1 mutants FANG, SHENGYUN UNIVERSITY OF MARYLAND BALTIMORE MD $303,206
ALS 2019 NINDS 5R01NS063964-10 TDP-43, RNA Metabolism, and ALS/FTD Pathology LINK, CHRISTOPHER UNIVERSITY OF COLORADO CO $338,516
ALS 2019 NIA 5R01NS104437-02 Deep Pathological Phenotyping in Frontotemporal Dementia and Motor Neuron Disease. SEELEY, WILLIAM UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $154,042
ALS 2019 NINDS 5R01NS104437-02 Deep Pathological Phenotyping in Frontotemporal Dementia and Motor Neuron Disease. SEELEY, WILLIAM UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $745,937
ALS 2019 NINDS 1R01NS110688-01 Examining neuronal resilience in a mouse model of sporadic ALS LEE, VIRGINIA UNIVERSITY OF PENNSYLVANIA PA $352,188
ALS 2019 NIA 1RF1AG064690-01 Defining modifiers and mechanisms of RAN translation PUGLISI, JOSEPH STANFORD UNIVERSITY CA $2,824,794
ALS 2019 NINDS 5F31NS103447-02 Intrinsic differences between cranial and spinal motor neurons as a route to ALS gene therapy IANNITELLI, DYLAN NEW YORK UNIVERSITY NY $30,262
ALS 2019 NIA 5R01NS099280-04 Hexanucleotide repeat translation in ALS and Frontotemporal Dementia TODD, PETER UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $81,417
ALS 2019 NINDS 5R01NS099280-04 Hexanucleotide repeat translation in ALS and Frontotemporal Dementia TODD, PETER UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $383,830
ALS 2019 NINDS 5K08NS107621-02 Investigating mechanisms of pathogenesis in TBK1-associated amyotrophic lateral sclerosis LY, CINDY WASHINGTON UNIVERSITY MO $163,080
ALS 2019 NIDCD 5K24DC016312-03 Prolonging Functional Speech in Persons with Amyotrophic Lateral Sclerosis: A Real-Time Virtual Vocal Tract GREEN, JORDAN MGH INSTITUTE OF HEALTH PROFESSIONS MA $189,841
ALS 2019 NINDS 1R21NS111275-01 FGF23: a novel biomarker in ALS and more KING, PETER UNIVERSITY OF ALABAMA AT BIRMINGHAM AL $421,545
ALS 2019 NINDS 5R01NS092788-05 Modeling the progression of SOD1-linked motor neuron disease BORCHELT, DAVID UNIVERSITY OF FLORIDA FL $328,125
ALS 2019 NINDS 5R01NS107347-02 Molecular mechanism of dipeptide repeat protein production from hexanucleotide repeats in C9ORF72-related ALS and FTD SUN, SHUYING JOHNS HOPKINS UNIVERSITY MD $358,203
ALS 2019 NINDS 1R21NS110994-01 Uncovering RNA signatures of C9ORF72-linked ALS and related disorders VAN BLITTERSWIJK, MARKA MAYO CLINIC JACKSONVILLE FL $430,375
ALS 2019 NINDS 1R61NS110960-01 High-throughput Screen for Discovery of Ciliary Neurotrophic Factor (CNTF) Receptor Agonists for the Treatment of Amyotrophic Lateral Sclerosis (ALS) ROSSOLL, WILFRIED MAYO CLINIC JACKSONVILLE FL $453,500
ALS 2019 NINDS 5R01NS092067-05 Regulation of glutamate transport in astrocyte subtypes and in ALS ROBINSON, MICHAEL CHILDREN'S HOSP OF PHILADELPHIA PA $455,786
ALS 2019 OD 5U54OD020351-05 5026 Project 6 - Amyotrophic Lateral Sclerosis Project LUTZ, CATHLEEN JACKSON LABORATORY ME $124,167
ALS 2019 NINDS 1R21NS111248-01 Defining The Mechanisms by Which NEK1 Genetic Variants Associated with ALS Patient Motor Neurons Lead to Motor Neuron Degeneration KISKINIS, EVANGELOS NORTHWESTERN UNIVERSITY AT CHICAGO IL $434,500
ALS 2019 NIDCD 1U01DC017844-01 Intuitive, complete neural control of tablet computers for communication HOCHBERG, LEIGH BROWN UNIVERSITY RI $837,287
ALS 2019 NINDS 1F32NS108598-01A1 Programming Human Chaperone Systems Against Neurodegenerative Disease BARBIERI, EDWARD UNIVERSITY OF PENNSYLVANIA PA $61,226
ALS 2019 NINDS 5R01NS104022-03 Expanding the chemical diversity of therapeutic oligonucleotides to treat neurodegenerative disorders KHVOROVA, ANASTASIA UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $664,751
ALS 2019 NINDS 5F31NS101966-03 Retromer dysfunction in amyotrophic lateral sclerosis PEREZ-TORRES, EDUARDO COLUMBIA UNIVERSITY HEALTH SCIENCES NY $23,131
ALS 2019 NIA 5R01NS102279-02 Dysregulation of p97/VCP disease mutants in IBM and FTLD-U CHOU, TSUI-FEN LA BIOMED RES INST/ HARBOR UCLA MED CTR CA $522,639
ALS 2019 NIA 1R15NS111374-01 Nuclear Surveillance of Expanded Tandem Repeat RNA in C9FTD/ALS Disease GAGNON, KEITH SOUTHERN ILLINOIS UNIVERSITY CARBONDALE IL $442,500
ALS 2019 NIA 5R21NS103118-02 Tractable models for C9orf72-linked RAN translation in ALS/FTD TROTTI, DAVIDE THOMAS JEFFERSON UNIVERSITY PA $195,000
ALS 2019 NCATS 5R21TR002277-02 A platform trial design to accelerate translational therapies in a canine disease model of ALS COATES, JOAN UNIVERSITY OF MISSOURI-COLUMBIA MO $196,284
ALS 2019 NIA 1R03NS111447-01 Dissecting the mechanisms that underlie mislocalization and aggregation of RNA binding proteins in neurodegenerative diseases SHALEM, OPHIR CHILDREN'S HOSP OF PHILADELPHIA PA $352,000
ALS 2019 NIA 1R01NS106236-01A1 Mechanisms of FUS Toxicity in Animal and Cellular Models of ALS/FTD. SHNEIDER, NEIL COLUMBIA UNIVERSITY HEALTH SCIENCES NY $113,400
ALS 2019 NINDS 1R01NS106236-01A1 Mechanisms of FUS Toxicity in Animal and Cellular Models of ALS/FTD. SHNEIDER, NEIL COLUMBIA UNIVERSITY HEALTH SCIENCES NY $534,600
ALS 2019 NIA 2R01AG031867-11 VCP in myopathy and dementia WEIHL, CONRAD WASHINGTON UNIVERSITY MO $700,761
ALS 2019 NINDS 5R01NS075839-08 Using human IPS cells to study fate, function and neurodegenerative disease IACOVITTI, LORRAINE THOMAS JEFFERSON UNIVERSITY PA $422,918
ALS 2019 NINDS 5R01NS093362-05 Defining the role of FUS phosphorylation in neurodegeneration KUKAR, THOMAS EMORY UNIVERSITY GA $383,053
ALS 2019 NINDS 5R01NS098516-04 Mechanisms of HIPK2 in neurodegeneration HUANG, ERIC UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $346,719
ALS 2019 NIGMS 5R01GM120607-04 Genomic profiling of pathological R-loop formation in human diseases. CHEDIN, FREDERIC UNIVERSITY OF CALIFORNIA AT DAVIS CA $305,428
ALS 2019 NINDS 5R01NS088645-05 Etiological Linkage of DNA Damage/Repair Deficiency in Neurodegenerative Diseases HEGDE, MURALIDHAR METHODIST HOSPITAL RESEARCH INSTITUTE TX $344,594
ALS 2019 NIA 5R01NS102730-03 Mechanisms underlying DNA double strand break response in Alzheimer?s disease and frontal temporal dementia TSAI, LI-HUEI MASSACHUSETTS INSTITUTE OF TECHNOLOGY MA $85,139
ALS 2019 NINDS 5R01NS102730-03 Mechanisms underlying DNA double strand break response in Alzheimer?s disease and frontal temporal dementia TSAI, LI-HUEI MASSACHUSETTS INSTITUTE OF TECHNOLOGY MA $316,235
ALS 2019 NIDCD 5R01DC017291-02 The development and validation of a novel tool for the assessment of bulbar dysfunction in ALS YUNUSOVA, YANA SUNNYBROOK RESEARCH INSTITUTE CANADA $473,743
ALS 2019 NIA 5K99AG057808-02 Exploring Mechanisms of Pathogenicity in C9ORF72 Frontotemporal Dementia and Amyotrophic Lateral Sclerosis BURBERRY, AARON HARVARD UNIVERSITY MA $108,454
ALS 2019 NIA 5R01NS027036-32 Disease mechanism in ALS and frontotemporal dementia CLEVELAND, DON LUDWIG INSTITUTE FOR CANCER RES LTD CA $137,338
ALS 2019 NINDS 5R01NS027036-32 Disease mechanism in ALS and frontotemporal dementia CLEVELAND, DON LUDWIG INSTITUTE FOR CANCER RES LTD CA $510,116
ALS 2019 NIA 5R01NS097542-04 RNA decay in amyotrophic lateral sclerosis and frontotemporal lobar degeneration BARMADA, SAMI UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $387,500
ALS 2019 NINDS 5R01NS099638-04 Investigation of ALS caused by mutant CHCHD10 SIDDIQUE, TEEPU NORTHWESTERN UNIVERSITY AT CHICAGO IL $507,349
ALS 2019 NINDS 5K08NS104273-03 FG-nucleoporins and nuclear transport disruption in C9ORF72-ALS/FTD HAYES, LINDSEY JOHNS HOPKINS UNIVERSITY MD $199,800
ALS 2019 NIA 5R01NS098819-04 Molecular Characterization of ALS/FTD in a novel C9orf72 BAC mouse model. RANUM, LAURA UNIVERSITY OF FLORIDA FL $123,534
ALS 2019 NINDS 5R01NS098819-04 Molecular Characterization of ALS/FTD in a novel C9orf72 BAC mouse model. RANUM, LAURA UNIVERSITY OF FLORIDA FL $582,373
ALS 2019 NIA 5UG3NS103870-03 Whole genome sequencing consortium on Frontotemporal dementia with underlying TDP-43 pathology RADEMAKERS, ROSA MAYO CLINIC JACKSONVILLE FL $1,227,787
ALS 2019 NINDS 5R01NS089586-04 Role of Oligodendroglia in the Pathogenesis of ALS KANG, SHIN TEMPLE UNIV OF THE COMMONWEALTH PA $340,104
ALS 2019 NINDS 5F31NS101807-03 Defining the molecular basis of substrate selection by diverse Hsp104 homologues MARCH, ZACHARY UNIVERSITY OF PENNSYLVANIA PA $32,186
ALS 2019 NINDS 5R21NS107761-02 Defining The Impaired Proteostasis Network in ALS Patient Motor Neurons KISKINIS, EVANGELOS NORTHWESTERN UNIVERSITY AT CHICAGO IL $197,500
ALS 2019 NINDS 5K08NS102396-03 Unraveling the mechanisms of motor neuron degeneration if Spinocerebellar Ataxia, type 1 ORENGO, JAMES BAYLOR COLLEGE OF MEDICINE TX $189,431
ALS 2019 NINDS 1F31NS111870-01 Engineering KapB2 to Disaggregate Disease-Linked Proteins FARE, CHARLOTTE UNIVERSITY OF PENNSYLVANIA PA $45,016
ALS 2019 NINDS 1R13NS111911-01 2019 Amyotrophic Lateral Sclerosis (ALS) & Related Motor Neuron Diseases GRC/GRS SATTLER, RITA GORDON RESEARCH CONFERENCES RI $10,000
ALS 2019 NIA 5R01AG059871-02 Deconstructing and challenging TDP-43 proteinopathies: from FTLD/ALS to Alzheimer's disease RINCON-LIMAS, DIEGO UNIVERSITY OF FLORIDA FL $381,250
ALS 2019 NINDS 1F31NS108579-01A1 Prefrontal cellular and circuitry mechanisms in a mouse model of C9ORF72-associated frontotemporal dementia. PHILLIPS, HANNAH UPSTATE MEDICAL UNIVERSITY NY $45,016
ALS 2019 NINDS 1F31NS110328-01A1 Therapeutic Genome Editing for Amyotrophic Lateral Sclerosis with a Compact, Hyper-accurate, and Versatile Cas9 EDRAKI, ALIREZA UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $29,995
ALS 2019 NINDS 5R01NS103195-02 Early development of small molecule neuroprotectants. LASMEZAS, CORINNE SCRIPPS FLORIDA FL $777,326
ALS 2019 NIA 2R01NS081303-06A1 Cellular and Molecular Mechanisms of FUS-related ALS/FTD PANDEY, UDAI UNIVERSITY OF PITTSBURGH AT PITTSBURGH PA $48,016
ALS 2019 NINDS 2R01NS081303-06A1 Cellular and Molecular Mechanisms of FUS-related ALS/FTD PANDEY, UDAI UNIVERSITY OF PITTSBURGH AT PITTSBURGH PA $336,117
ALS 2019 NIA 5R01AG058233-02 Defining trajectories of dynamic biomarkers for C9ORF72 repeat expansion carriers LEE, SUZEE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $563,724
ALS 2019 NINDS 1R43NS110077-01A1 Matrix Metalloproteinase-2/-9 Inhibitor For The Treatment Of ALS SUCHOLEIKI, IRVING AQUILUS PHARMACEUTICALS, INC. MA $457,639
ALS 2019 NIA 1R01NS108769-01A1 Disruption of nucleocytoplasmic transport in FUS-related neurodegenerative diseases BOSCO, DARYL UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $142,612
ALS 2019 NINDS 1R01NS108769-01A1 Disruption of nucleocytoplasmic transport in FUS-related neurodegenerative diseases BOSCO, DARYL UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $546,596
ALS 2019 NINDS 1R01NS111990-01 Next-generation antisense therapeutics for ALS and frontotemporal dementia WATTS, JONATHAN UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $660,421
ALS 2019 NINDS 5R44NS070385-06 Electrical impedance myography technology for quantitative, at-home muscle assessment in amyotrophic lateral sclerosis and other neuromuscular disorders. LUPTON, ELMER MYOLEX, INC. MA $632,777
ALS 2019 NINDS 5K08NS094744-06 TDP43 mRNA complex transport in physiologic and pathologic states GOPAL, PALLAVI YALE UNIVERSITY CT $185,236
ALS 2019 NINDS 5R21NS104520-02 Targeting astrocytic toxicity for ALS therapy FUJITA, HIBIKI WEILL MEDICAL COLL OF CORNELL UNIV NY $211,875
ALS 2019 NINDS 5R21NS109847-02 Inhibiting Translation of Endogenous G4C2-Containing RNA As a Novel Therapy for C9ORF72-ALS RICHTER, JOEL UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $209,375
ALS 2019 NINDS 5R01NS107442-02 Mechanisms of Axon Pathology in ALS PRZEDBORSKI, SERGE COLUMBIA UNIVERSITY HEALTH SCIENCES NY $553,565
ALS 2019 NINDS 5R21NS109917-02 A Novel approach to therapy in ALS and ALS/Dementia using new insights from ALS5/SPG11 SIDDIQUE, TEEPU NORTHWESTERN UNIVERSITY AT CHICAGO IL $237,000
ALS 2019 NINDS 5R21NS106392-02 Testing RNA Aptamers in ALS Mouse Models NIU, LI STATE UNIVERSITY OF NEW YORK AT ALBANY NY $176,775
ALS 2019 NINDS 1R43NS112047-01 Rapid Production of Regional and Disease Specific Human Astrocytes for CNS Drug Discovery DU, ZHONG-WEI BRAINXELL, INC. WI $224,797
ALS 2019 NINDS 5R01NS105479-02 Pre-Symptomatic Familial ALS (Pre-fALS) Study - Prelude to a Treatment Trial BENATAR, MICHAEL UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $559,758
ALS 2019 NIEHS 5R21ES027663-02 Modeling ALS-PDC: Aligning BMAA toxicity with the birth of neurons involved in ALS-PDC and with aging CHARLTON, CLIVEL MEHARRY MEDICAL COLLEGE TN $181,875
ALS 2019 NCATS 5UG3NS105703-03 Development of a Microphysiological Organ-on-Chip System to Model Amyotrophic SVENDSEN, CLIVE CEDARS-SINAI MEDICAL CENTER CA $625,000
ALS 2019 NINDS 5UG3NS105703-03 Development of a Microphysiological Organ-on-Chip System to Model Amyotrophic SVENDSEN, CLIVE CEDARS-SINAI MEDICAL CENTER CA $623,105
ALS 2019 NIA 5R01NS097850-04 The Role of C9ORF72 Protein Function in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia ICHIDA, JUSTIN UNIVERSITY OF SOUTHERN CALIFORNIA CA $51,562
ALS 2019 NINDS 5R01NS097850-04 The Role of C9ORF72 Protein Function in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia ICHIDA, JUSTIN UNIVERSITY OF SOUTHERN CALIFORNIA CA $380,165
ALS 2019 NINDS 5F31NS108632-02 Transforming Growth Factor Beta Signaling in a mouse model of Amyotrophic Lateral Sclerosis BRAINE, CATHERINE COLUMBIA UNIVERSITY HEALTH SCIENCES NY $50,016
ALS 2019 NINDS 5K01NS110449-02 Selectivity for Kinesin-driven Transport of Axonal RNA Granules FUKUDA, YUSUKE DANA-FARBER CANCER INST MA $106,615
ALS 2019 NINDS 5F31NS110301-02 Effect of neurodegenerative disease mutations and post-translational modifications on hnRNPA2 structure, function, and interactions in phase-separated ribonucleoprotein granules RYAN, VERONICA BROWN UNIVERSITY RI $45,016
ALS 2019 NINDS 1R01NS112255-01 Spinal circuitry for ventilatory control and compensation CRONE, STEVEN CINCINNATI CHILDRENS HOSP MED CTR OH $347,813
ALS 2019 NCATS 2U54NS092091-06 6144 Clinical Research in ALS & Related Disorders for Therapeutic Development (CReATe) - Administrative Core BENATAR, MICHAEL UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $168,760
ALS 2019 NINDS 2U54NS092091-06 6144 Clinical Research in ALS & Related Disorders for Therapeutic Development (CReATe) - Administrative Core BENATAR, MICHAEL UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $168,760
ALS 2019 NCATS 2U54NS092091-06 6145 Clinical Research in ALS & Related Disorders for Therapeutic Development (CReATe) - Project Core #1 BENATAR, MICHAEL UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $334,147
ALS 2019 NINDS 2U54NS092091-06 6145 Clinical Research in ALS & Related Disorders for Therapeutic Development (CReATe) - Project Core #1 BENATAR, MICHAEL UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $334,148
ALS 2019 NCATS 2U54NS092091-06 6146 Clinical Research in ALS & Related Disorders for Therapeutic Development (CReATe) - Project Core #2 TAYLOR, JOSEPH UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $233,769
ALS 2019 NINDS 2U54NS092091-06 6146 Clinical Research in ALS & Related Disorders for Therapeutic Development (CReATe) - Project Core #2 TAYLOR, JOSEPH UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $233,769
ALS 2019 NCATS 2U54NS092091-06 6147 Clinical Research in ALS & Related Disorders for Therapeutic Development (CReATe) - Project Core #3 MCMILLAN, COREY UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $44,833
ALS 2019 NINDS 2U54NS092091-06 6147 Clinical Research in ALS & Related Disorders for Therapeutic Development (CReATe) - Project Core #3 MCMILLAN, COREY UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $44,834
ALS 2019 NCATS 2U54NS092091-06 6148 Clinical Research in ALS & Related Disorders for Therapeutic Development (CReATe) - Pilot Core BENATAR, MICHAEL UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $36,840
ALS 2019 NINDS 2U54NS092091-06 6148 Clinical Research in ALS & Related Disorders for Therapeutic Development (CReATe) - Pilot Core BENATAR, MICHAEL UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $36,840
ALS 2019 NCATS 2U54NS092091-06 6149 Clinical Research in ALS & Related Disorders for Therapeutic Development (CReATe) - Career Enhancement Core BURNS, TED UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $44,409
ALS 2019 NINDS 2U54NS092091-06 6149 Clinical Research in ALS & Related Disorders for Therapeutic Development (CReATe) - Career Enhancement Core BURNS, TED UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $44,410
ALS 2019 NINDS 1K22NS112678-01 Exploring functional complexes and disease networks within human RNA-binding protein interactomes BRANNAN, KRISTOPHER UNIVERSITY OF CALIFORNIA, SAN DIEGO CA $124,929
ALS 2019 NINDS 1R21NS113025-01 A new approach to immunotherapy for ALS XU, ZUOSHANG UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $460,625
ALS 2019 NINDS 1R03NS112972-01 Discovery of Small Molecules that Block Supt4h1-Supt5h Dimerization for Potential C9FTD/ALS Therapeutics GAGNON, KEITH SOUTHERN ILLINOIS UNIVERSITY CARBONDALE IL $87,875
ALS 2019 RMAP 1UH2EB028904-01 Non-Invasive Tracking of Genome-Corrected iPS cells in ALS BULTE, JEFF JOHNS HOPKINS UNIVERSITY MD $243,046
ALS 2019 NIA 1RF1AG056320-01A1 Mitochondrial TDP-43 in Alzheimer's Disease WANG, XINGLONG CASE WESTERN RESERVE UNIVERSITY OH $2,009,583
ALS 2019 NIA 1R01AG061708-01A1 Novel Protein Aggregation Inhibitors and Upper Motor Neuron Stabilizers for ALS and other Neurodegenerative Diseases OZDINLER, PEMBE HANDE NORTHWESTERN UNIVERSITY AT CHICAGO IL $671,753
ALS 2019 NIAMS 1R01AR074875-01A1 Mitochondrial inner membrane architecture in skeletal muscle pathophysiology LU, BINGWEI STANFORD UNIVERSITY CA $344,341
ALS 2019 NINDS 3R01NS093362-04S1 Defining the role of FUS phosphorylation in neurodegeneration KUKAR, THOMAS EMORY UNIVERSITY GA $30,925
ALS 2019 NINDS 1K08NS104270-01A1 Novel pathways in C9ORF72-associated ALS and dementia MORDES, DANIEL MASSACHUSETTS GENERAL HOSPITAL MA $199,684
ALS 2019 NINDS 3R35NS097263-03S1 Innovating Yeast and Human Genetics Approaches to Define Mechanisms of Neurodegenerative Disease GITLER, AARON STANFORD UNIVERSITY CA $95,776
ALS 2019 NINDS 1R21NS109661-01A1 Multiplex modeling of ALS with barcoded human pluripotent stem cell lines WICHTERLE, HYNEK COLUMBIA UNIVERSITY HEALTH SCIENCES NY $438,800
ALS 2019 NINDS 1R21NS109678-01A1 Pharmacologic inhibition of ribonucleoprotein droplet maturation FERREON, ALLAN CHRIS BAYLOR COLLEGE OF MEDICINE TX $440,000
ALS 2019 NINDS 1R01NS109150-01A1 Contribution of astrocytes to mutant FUS-linked Amyotrophic Lateral Sclerosis PASINELLI, PIERA THOMAS JEFFERSON UNIVERSITY PA $341,250
ALS 2019 NINDS 1F31NS110119-01A1 Abnormal Matrin 3 turnover and nucleic acid-binding in ALS and related disorders MALIK, AHMED UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $37,072
ALS 2019 NIA 1RF1AG064822-01 Gene Deregulation in Cortical Dementia XIA, XU-GANG UNIVERSITY OF CENTRAL FLORIDA FL $3,612,690
ALS 2019 NIA 1RF1NS113636-01 Molecular Assembly and Disassembly of RNA-Protein Complexes Implicated in ALS/FTD MYONG, SUA JOHNS HOPKINS UNIVERSITY MD $1,971,938
ALS 2019 NINDS 1R41NS113642-01 MITOFUSIN AGONISTS TO TREAT NEURODEGENERATIVE DISEASE DORN, GERALD MITOCHONDRIA IN MOTION, INC. MO $254,062
ALS 2019 NINDS 1R01NS113917-01 Gene Therapy Targeting of CNTFRalpha and CLC in Muscle to Treat ALS MACLENNAN, ALEXANDER UNIVERSITY OF CINCINNATI OH $424,160
ALS 2019 NINDS 1R21NS114908-01 Mechanistic insight into RNA-mediated toxicity of C9orf72-linked ALS/FTD BASSELL, GARY EMORY UNIVERSITY GA $230,618
ALS 2019 NIA 3R01NS091836-05S1 Neurodegeneration mechanisms common to both ALS and AD ELBASIOUNY, SHERIF WRIGHT STATE UNIVERSITY OH $286,836
ALS 2019 NIGMS 3U01GM117175-03S1 High-Content Screening to Identify Small Molecules for Refolding SOD1 Mutants FANG, SHENGYUN UNIVERSITY OF MARYLAND BALTIMORE MD $152,645
ALS 2019 NIA 1R61NS115089-01 Full human gene-replacement mouse models of ADRDs KOOB, MICHAEL UNIVERSITY OF MINNESOTA MN $1,507,494
ALS 2019 NIA 1R56AG058732-01A1 Resistance and Vulnerability for Alzheimer's and Related Pathologies MCMILLAN, COREY UNIVERSITY OF PENNSYLVANIA PA $799,044
ALS 2019 NINDS 1R41NS112029-01A1 Improving ALS Diagnosis using Needle I-EMG SANCHEZ, BENJAMIN HAYSTACK DIAGNOSTICS, INC. MA $224,999
ALS 2019 NINDS 1F31NS111851-01A1 High-throughput disease modeling to uncover shared and unique characteristics among neurodegenerative diseases RESNICK, SAMUEL COLUMBIA UNIVERSITY HEALTH SCIENCES NY $45,016
ALS 2019 NINDS 1F31NS115257-01 Investigating the mechanism of UPF1-mediated rescue of TDP-43-based models of ALS and FTD GOMEZ, NICOLAS UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $37,072
ALS 2019 NINDS 1F31NS111859-01A1 Uncovering the transcriptional regulatory roles of ataxin-2 in neuronal function and neurodegenerative disease MARINA, RYAN UNIVERSITY OF CALIFORNIA, SAN DIEGO CA $37,858
ALS 2019 NIA 1F30AG066373-01 Tissue-specific modulation of Apolipoprotein E in neurodegeneration FERGUSON, CHANTAL UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $32,209
ALS 2019 NIA 1F30AG063486-01A1 Therapeutic targeting of ATXN2 for sporadic amyotrophic lateral sclerosis (ALS) TAYLOR, AMY UNIVERSITY OF CALIFORNIA, SAN DIEGO CA $37,456
ALS 2019 NINDS 1F99NS115339-01 The Role of Homeostenosis in Bulbar Function in ALS and Aging ROBISON, RAELE UNIVERSITY OF FLORIDA FL $38,963
ALS 2019 NIEHS 3R01ES024064-05S1 Environmental Metals, Excitotoxicity and ALS ATCHISON, WILLIAM MICHIGAN STATE UNIVERSITY MI $8,117
ALS 2019 NIA 3RF1AG057443-01S3 Validation of Antibody Reagents for 15 High Priority AMP-AD Targets MANGRAVITE, LARA SAGE BIONETWORKS WA $287,500
ALS 2019 NIA 1R56NS112296-01 Mitochondrial pathogenic pathways in amyotrophic lateral sclerosis and frontotemporal dementia KIM, NAM CHUL UNIVERSITY OF MINNESOTA MN $385,000
ALS 2019 NIA 3R01NS089586-03S1 Role of Oligodendroglia in the Pathogenesis of ALS KANG, SHIN TEMPLE UNIV OF THE COMMONWEALTH PA $354,797
ALS 2019 NIA 3R35NS097275-03S1 Molecular Genetic Insight into Neurodegenerative Disease from Drosophila BONINI, NANCY UNIVERSITY OF PENNSYLVANIA PA $162,000
ALS 2019 NIA 1R56NS105806-01A1 Regulation of TDP-43 function and pathology via phosphorylation in ALS and frontotemporal dementia AYALA, YUNA SAINT LOUIS UNIVERSITY MO $378,750
ALS 2019 NIA 3R01NS091299-05S1 RNA dysregulation in neurodegeneration ZARNESCU, DANIELA UNIVERSITY OF ARIZONA AZ $377,974
ALS 2019 NINDS 7R21NS106313-03 Analysis of Sensory Neurons to Understand and Identify Factors to Treat ALS VALDEZ, GREGORIO BROWN UNIVERSITY RI $159,144
ALS 2019 NINDS 4R37NS040389-16 Molecular Genetic Characterization of SCA8 RANUM, LAURA UNIVERSITY OF FLORIDA FL $712,855
ALS 2019 NINDS 1ZIANS002976-21 Spasticity and Upper Motor Neuron Disorders FLOETER, MARY KAY NIH $161,162
ALS 2019 NINDS 1ZIANS003146-05 Natural history and biomarker discovery in C9orf72 Amyotrophic lateral sclerosis and frontotemporal dementia FLOETER, MARY KAY NIH $1,091,489
ALS 2019 NIA 1ZIAAG000943-11 Function and Pathogenic Mechanism of VAPB in ALS and Other Motor Neuron Diseases CAI, HUAIBIN NIH $25,984
ALS 2019 NIA 1ZIAAG000933-12 Genetic etiology of Amyotrophic Lateral Sclerosis TRAYNOR, BRYAN NIH $1,168,456
ALS 2019 NIA 1ZIAAG000934-11 Genetic etiology of Fronto-Temporal Dementia, a dementia related to Alzheimers disease TRAYNOR, BRYAN NIH $811,428
ALS 2019 NINDS 4R44NS105156-03 PIKFYVE antagonism as a therapy for C9ORF72-ALS/FTD ALWORTH, SAMUEL ACURASTEM, INC. CA $1,316,216
ALS 2019 NCATS 1ZIATR000317-03 p97 inhibitors for treatment of IBMPFD/ALS SIMEONOV, ANTON NIH $132,650
ALS 2019 NCATS 1ZIATR000319-03 Chemical chaperones for refolding mutant SOD1 SIMEONOV, ANTON NIH $132,650
ALS 2019 NICHD 1ZIAHD008892-11 Mechanisms of Motor Neuron Disease KALER, STEPHEN NIH $254,999
ALS 2019 NINDS 1ZIANS003038-13 Studies of Hereditary Neurological Disease: Disease Mechanisms FISCHBECK, KENNETH NIH $1,526,828
ALS 2019 NINDS 1ZIANS003130-09 Neuropathogenesis of Retroviral Infections NATH, AVINDRA NIH $5,580,007
ALS 2019 NINDS 1ZIANS003134-08 Study the pathogenesis of neurological disorders using human neural cultures derived from patient peripheral blood CD34 cells NATH, AVINDRA NIH $1,108,488
ALS 2019 NINDS 1ZIANS003155-04 Mechanisms of inherited neurodegenerative diseases WARD, MICHAEL NIH $1,266,452
ALS 2019 NIA 3R01NS105756-02S1 An optogenetic approach to establish the interplay between stress granules and TDP-43 proteinopathy in ALS/FTD DONNELLY, CHRISTOPHER UNIVERSITY OF PITTSBURGH AT PITTSBURGH PA $46,722


  • Download Readers:
  • Download Adobe PDF Reader
  • Download Microsoft PowerPoint Viewer
  • Download Microsoft Word Viewer
  • Download Microsoft Excel Viewer