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RCDC

Project Listing by Category


Back to Estimates of Funding for Various Research, Condition, and Disease Categories (RCDC) Click the column headings to sort project listings.
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CategoryFYFunding ICProject NumberSub Project #Project TitlePI NameOrg NameState / CountryAmount
Transmissible Spongiform Encephalopathy (TSE) 2018 NIGMS 5R01GM099836-06 Defining the mechanistic basis of a prion disaggregase SHORTER, JAMES UNIVERSITY OF PENNSYLVANIA PA $339,308
Transmissible Spongiform Encephalopathy (TSE) 2018 NIA 5R01NS065244-08 Mechanisms of Prion Protein Toxicity HARRIS, DAVID BOSTON UNIVERSITY MEDICAL CAMPUS MA $111,694
Transmissible Spongiform Encephalopathy (TSE) 2018 NINDS 5R01NS065244-08 Mechanisms of Prion Protein Toxicity HARRIS, DAVID BOSTON UNIVERSITY MEDICAL CAMPUS MA $526,550
Transmissible Spongiform Encephalopathy (TSE) 2018 NINDS 5F32NS095587-03 Characterizing the Cellular Biology of Prion Strains and the Factors that Drive Prion Pathogenesis LOPEZ, TIMOTHY UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $67,647
Transmissible Spongiform Encephalopathy (TSE) 2018 NINDS 5R21NS101659-02 Identification of Anti-Prion Drug Targets HARRIS, DAVID BOSTON UNIVERSITY MEDICAL CAMPUS MA $206,094
Transmissible Spongiform Encephalopathy (TSE) 2018 NINDS 5R21NS099928-02 Combination Chemotherapy for Treatment of Prion Disease SUPATTAPONE, SURACHAI DARTMOUTH COLLEGE NH $202,500
Transmissible Spongiform Encephalopathy (TSE) 2018 NINDS 2R01NS061902-09 Transmission and Pathogenesis of Chronic Wasting Disease (CWD) HOOVER, EDWARD COLORADO STATE UNIVERSITY CO $454,524
Transmissible Spongiform Encephalopathy (TSE) 2018 NIA 1R01NS100876-01A1 Prion and non-prion induction mechanisms of alpha-synuclein pathology GIASSON, BENOIT UNIVERSITY OF FLORIDA FL $379,836
Transmissible Spongiform Encephalopathy (TSE) 2018 NIA 5P01AG002132-37 8435 Core B: Science GILES, KURT UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $239,866
Transmissible Spongiform Encephalopathy (TSE) 2018 NIA 5P01AG002132-37 8437 Core D: Animals PRUSINER, STANLEY UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $320,168
Transmissible Spongiform Encephalopathy (TSE) 2018 NIA 5P01AG002132-37 8438 Project 1: Abeta, tau and PrP prions causing neurodegenerative diseases PRUSINER, STANLEY UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $392,282
Transmissible Spongiform Encephalopathy (TSE) 2018 NIA 5P01AG002132-37 8439 Project 2: Structural studies of prions SOUTHWORTH, DANIEL UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $278,166
Transmissible Spongiform Encephalopathy (TSE) 2018 NIA 5P01AG002132-37 8440 Project 3: Assembly and structures of Abeta peptides. DEGRADO, WILLIAM UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $332,713
Transmissible Spongiform Encephalopathy (TSE) 2018 NIA 5P01AG002132-37 8441 Project 4: Structural modeling of Abeta, tau and PrP prion self-assembly SALI, ANDREJ UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $235,160
Transmissible Spongiform Encephalopathy (TSE) 2018 NIGMS 5R01GM115941-03 Amyloid aggregation and prion formation in bacteria HOCHSCHILD, ANN HARVARD MEDICAL SCHOOL MA $474,537
Transmissible Spongiform Encephalopathy (TSE) 2018 NIA 5P50AG023501-15 5930 Core B: Clinical Core KRAMER, JOEL UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $402,159
Transmissible Spongiform Encephalopathy (TSE) 2018 NIGMS 5R01GM110448-05 Structural biology of yeast prions. GUO, ZHEFENG UNIVERSITY OF CALIFORNIA LOS ANGELES CA $292,600
Transmissible Spongiform Encephalopathy (TSE) 2018 NIAID 5P01AI077774-08 5320 Administrative Core SOTO, CLAUDIO UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON TX $153,829
Transmissible Spongiform Encephalopathy (TSE) 2018 NIAID 5P01AI077774-08 5321 Science Core B TELLING, GLENN COLORADO STATE UNIVERSITY CO $313,305
Transmissible Spongiform Encephalopathy (TSE) 2018 NIAID 5P01AI077774-08 5322 Mechanisms of Prion Transmission, Evolution and Adaptation TELLING, GLENN COLORADO STATE UNIVERSITY CO $552,015
Transmissible Spongiform Encephalopathy (TSE) 2018 NIAID 5P01AI077774-08 5323 Zoonotic potential of CWD and influence of environmental contamination on prion propagation SOTO, CLAUDIO UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON TX $556,373
Transmissible Spongiform Encephalopathy (TSE) 2018 NIAID 5P01AI077774-08 5324 CWD Prion Shedding and Environmental Contamination: Role in Transmission and Zoonotic Potential HOOVER, EDWARD COLORADO STATE UNIVERSITY CO $612,915
Transmissible Spongiform Encephalopathy (TSE) 2018 NINDS 5R01NS092145-08 The iron modulatory function of prion protein and prion disorders SINGH, NEENA CASE WESTERN RESERVE UNIVERSITY OH $494,856
Transmissible Spongiform Encephalopathy (TSE) 2018 NIAID 5R01AI112956-05 Detection and Characterization of Blood-borne Prions MATHIASON, CANDACE COLORADO STATE UNIVERSITY CO $378,665
Transmissible Spongiform Encephalopathy (TSE) 2018 NIGMS 5R35GM118042-04 Cellular Mechanisms and Consequences of Protein Misfolding and Resolution SERIO, TRICIA UNIVERSITY OF MASSACHUSETTS AMHERST MA $387,095
Transmissible Spongiform Encephalopathy (TSE) 2018 OD 5F30OD021442-04 Characterizing the Role of Protein Interactions in Prion Disease Species Barriers DAVENPORT, KRISTEN COLORADO STATE UNIVERSITY CO $49,098
Transmissible Spongiform Encephalopathy (TSE) 2018 NIAID 5R01AI132695-02 Shedding, retention and spreading of chronic wasting disease prions in the environment MORALES, RODRIGO UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON TX $518,130
Transmissible Spongiform Encephalopathy (TSE) 2018 NINDS 5R01NS083687-05 Structural correlates of prion strain, phenotype and infectivity in human prion d GAMBETTI, PIERLUIGI CASE WESTERN RESERVE UNIVERSITY OH $585,285
Transmissible Spongiform Encephalopathy (TSE) 2018 NINDS 5R01NS069566-08 Mechanisms of Prion Aggregation and Species Barriers SIGURDSON, CHRISTINA UNIVERSITY OF CALIFORNIA, SAN DIEGO CA $339,063
Transmissible Spongiform Encephalopathy (TSE) 2018 NIGMS 5R01GM065790-16 Molecular aspects of copper and zinc binding to the prion protein MILLHAUSER, GLENN UNIVERSITY OF CALIFORNIA SANTA CRUZ CA $313,632
Transmissible Spongiform Encephalopathy (TSE) 2018 NIA 5P30AG008051-29 5041 Core D. Neuropathology Core (with IBR Subcontract) WISNIEWSKI, THOMAS NEW YORK UNIVERSITY SCHOOL OF MEDICINE NY $192,336
Transmissible Spongiform Encephalopathy (TSE) 2018 NINDS 5R01NS088604-04 Cervid to human prion transmission KONG, QINGZHONG CASE WESTERN RESERVE UNIVERSITY OH $346,720
Transmissible Spongiform Encephalopathy (TSE) 2018 NIGMS 5R01GM126548-02 Mathematical Strategies to Uncover the Molecular Basis of Prion Transitions SINDI, SUZANNE UNIVERSITY OF CALIFORNIA, MERCED CA $213,561
Transmissible Spongiform Encephalopathy (TSE) 2018 NINDS 5R01NS076896-07 Mechanisms of Prion Spread SIGURDSON, CHRISTINA UNIVERSITY OF CALIFORNIA, SAN DIEGO CA $339,063
Transmissible Spongiform Encephalopathy (TSE) 2018 NIAID 5R01AI128925-02 Role of prion protein sialylation in prion diseases BASKAKOV, ILIA UNIVERSITY OF MARYLAND BALTIMORE MD $706,228
Transmissible Spongiform Encephalopathy (TSE) 2018 NIGMS 5R35GM119790-03 Using naturally-occurring fungal prions as models of neurodegenerative protein misfolding SHEWMAKER, FRANK HENRY M. JACKSON FDN FOR THE ADV MIL/MED MD $309,334
Transmissible Spongiform Encephalopathy (TSE) 2018 NIGMS 5R01GM056350-20 Exploring the toxicity of aggregates associated with protein-misfolding diseases LIEBMAN, SUSAN UNIVERSITY OF NEVADA RENO NV $370,247
Transmissible Spongiform Encephalopathy (TSE) 2018 NIA 5R01NS097490-02 Solid-state NMR Structural Characterizations of Polymorphic Transthyretin Amyloids LIM, KWANG HUN EAST CAROLINA UNIVERSITY NC $138,269
Transmissible Spongiform Encephalopathy (TSE) 2018 NINDS 1R01NS102301-01A1 Dissecting the Mechanism of Prion Formation with a Permissive Host SUPATTAPONE, SURACHAI DARTMOUTH COLLEGE NH $553,817
Transmissible Spongiform Encephalopathy (TSE) 2018 NIAID 5P01AI106705-05 7014 Molecular and Structural Basis of Prion Protein Conversion to the infectious Form SUREWICZ, WITOLD CASE WESTERN RESERVE UNIVERSITY OH $840,813
Transmissible Spongiform Encephalopathy (TSE) 2018 NIAID 5P01AI106705-05 7016 Mechanisms of Human Prion Disease Diversity GAMBETTI, PIERLUIGI CASE WESTERN RESERVE UNIVERSITY OH $187,765
Transmissible Spongiform Encephalopathy (TSE) 2018 NIAID 5P01AI106705-05 7017 Administrative Core SUREWICZ, WITOLD CASE WESTERN RESERVE UNIVERSITY OH $94,607
Transmissible Spongiform Encephalopathy (TSE) 2018 NIAID 5P01AI106705-05 7018 Animal Core CONLON, RONALD CASE WESTERN RESERVE UNIVERSITY OH $294,927
Transmissible Spongiform Encephalopathy (TSE) 2018 NIAID 5P01AI106705-05 7019 Neuropathology Core - P Gambetti GAMBETTI, PIERLUIGI CASE WESTERN RESERVE UNIVERSITY OH $122,018
Transmissible Spongiform Encephalopathy (TSE) 2018 NIGMS 5F32GM125162-02 Using self-templating proteins to spatiotemporally organize biochemistry JAKOBSON, CHRISTOPHER STANFORD UNIVERSITY CA $58,038
Transmissible Spongiform Encephalopathy (TSE) 2018 NINDS 1R01NS103195-01A1 Early development of small molecule neuroprotectants. LASMEZAS, CORINNE SCRIPPS FLORIDA FL $755,830
Transmissible Spongiform Encephalopathy (TSE) 2018 NIAID 5F31AI122592-03 Developing in vitro assays to identify small molecules that inhibit human prions MINIKEL, ERIC HARVARD MEDICAL SCHOOL MA $32,192
Transmissible Spongiform Encephalopathy (TSE) 2018 NIA 1R43AG057421-01A1 Development of Novel Prion Disease Diagnostic SARRAF, STELLA AMYDIS DIAGNOSTICS, INC. CA $408,225
Transmissible Spongiform Encephalopathy (TSE) 2018 NINDS 1R01NS107246-01 Mechanisms of prion spread and establishment of infection BARTZ, JASON CREIGHTON UNIVERSITY NE $514,980
Transmissible Spongiform Encephalopathy (TSE) 2018 NINDS 1R01NS103848-01A1 Replication mechanism of human prions SAFAR, JIRI CASE WESTERN RESERVE UNIVERSITY OH $514,880
Transmissible Spongiform Encephalopathy (TSE) 2018 NIGMS 1R01GM126318-01A1 Prion-mediated protein aggregation/co-aggregation and cellular consequence DU, ZHIQIANG NORTHWESTERN UNIVERSITY AT CHICAGO IL $317,250
Transmissible Spongiform Encephalopathy (TSE) 2018 NINDS 5F31NS101807-02 Defining the molecular basis of substrate selection by diverse Hsp104 homologues MARCH, ZACHARY UNIVERSITY OF PENNSYLVANIA PA $44,524
Transmissible Spongiform Encephalopathy (TSE) 2018 NINDS 2R01NS045585-16 Self-Propagating Mechanism of Prion Diseases BASKAKOV, ILIA UNIVERSITY OF MARYLAND BALTIMORE MD $508,003
Transmissible Spongiform Encephalopathy (TSE) 2018 NINDS 1R21NS105498-01A1 Molecular basis of spongiform encephalopathy in prion disease SIGURDSON, CHRISTINA UNIVERSITY OF CALIFORNIA, SAN DIEGO CA $235,375
Transmissible Spongiform Encephalopathy (TSE) 2018 NINDS 5F31NS103588-02 Targeting vesicular transport pathways in prion disease LAWRENCE, JESSICA UNIVERSITY OF CALIFORNIA, SAN DIEGO CA $38,024
Transmissible Spongiform Encephalopathy (TSE) 2018 NINDS 1R01NS109532-01 Role of skin prions in disease transmission and diagnostic testing of human prion disease ZOU, WEN-QUAN CASE WESTERN RESERVE UNIVERSITY OH $573,927
Transmissible Spongiform Encephalopathy (TSE) 2018 NINDS 1R01NS109376-01 Characterizing the strain and host range properties of prions causing emergent forms of chronic wasting disease TELLING, GLENN COLORADO STATE UNIVERSITY CO $482,214
Transmissible Spongiform Encephalopathy (TSE) 2018 NINDS 1R01NS103763-01A1 Mechanisms of prion strain dynamics BARTZ, JASON CREIGHTON UNIVERSITY NE $395,021
Transmissible Spongiform Encephalopathy (TSE) 2018 NIA 1RF1AG061874-01 Relationships between conformational strains of tau and amyloid-beta, TREM2 and APOE variants, and phenotypic variations of Alzheimer's Disease CONDELLO, CARLO UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $1,996,800
Transmissible Spongiform Encephalopathy (TSE) 2018 NINDS 1R21NS107755-01A1 Genomic and Proteomic Analysis of Prion Synaptotoxicity HARRIS, DAVID BOSTON UNIVERSITY MEDICAL CAMPUS MA $247,500
Transmissible Spongiform Encephalopathy (TSE) 2018 NINDS 1R21NS110409-01 Probing prion clearance through interstitial fluid and perivascular pathways SIGURDSON, CHRISTINA UNIVERSITY OF CALIFORNIA, SAN DIEGO CA $235,625
Transmissible Spongiform Encephalopathy (TSE) 2018 NINDS 3R01NS097490-02S1 Solid-state NMR Structural Characterizations of Polymorphic Transthyretin Amyloids LIM, KWANG HUN EAST CAROLINA UNIVERSITY NC $40,127
Transmissible Spongiform Encephalopathy (TSE) 2018 NIDDK 275201800129U-0-0-1 CREUTZFELDT-JAKOB DISEASE SURVEILLANCE IN RECIPIENTS OF HUMAN GROWTH HORMONE NO PI IDENTIFIED WESTAT, INC. MD $235,400
Transmissible Spongiform Encephalopathy (TSE) 2018 NIDDK 1ZIADK024950-12 Biological Roles and Structures of Yeast Prions WICKNER, REED NIH $1,659,098
Transmissible Spongiform Encephalopathy (TSE) 2018 NIDDK 1ZIADK024954-09 Chaperone-amyloid interactions MASISON, DANIEL NIH $436,742
Transmissible Spongiform Encephalopathy (TSE) 2018 NIDDK 1ZIADK024946-21 Yeast prions and Hsp70 chaperones MASISON, DANIEL NIH $655,113
Transmissible Spongiform Encephalopathy (TSE) 2018 NIDDK 1ZIADK075031-10 Structural Studies of Prion Fibrils and Other Protein Fibrils TYCKO, ROBERT NIH $388,120
Transmissible Spongiform Encephalopathy (TSE) 2018 NIA 1R56AG055619-01A1 TLC-Pre-gPrD: Tracking Longitudinal Change in Presymptomatic genetic Prion Disease GESCHWIND, MICHAEL UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $799,485
Transmissible Spongiform Encephalopathy (TSE) 2018 NIAMS 1ZIAAR041157-12 Structural Biology of Amyloid and Amyloid-like Proteins STEVEN, ALASDAIR NIH $99,547
Transmissible Spongiform Encephalopathy (TSE) 2018 NIA 1R56AG061878-01 Isolation, characterization and pathogenic role of self-propagating conformational amyloid-beta strains SOTO, CLAUDIO UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON TX $550,552
Transmissible Spongiform Encephalopathy (TSE) 2018 NIAID 1ZIAAI000580-29 Structures and Activities of Prions and Prion Proteins CAUGHEY, BYRON NIH $509,094
Transmissible Spongiform Encephalopathy (TSE) 2018 NIAID 1ZIAAI000752-23 Molecular Genetics Of Scrapie Pathogenesis PRIOLA, SUZETTE NIH $1,135,879
Transmissible Spongiform Encephalopathy (TSE) 2018 NIAID 1ZIAAI000937-15 Biology of Prion Protein and the TSE Diseases CHESEBRO, BRUCE NIH $971,520
Transmissible Spongiform Encephalopathy (TSE) 2018 NIAID 1ZIAAI000983-13 Study of CWD Deer and Elk Prion Disease in Nonhuman Primates CHESEBRO, BRUCE NIH $458,140
Transmissible Spongiform Encephalopathy (TSE) 2018 NIAID 1ZIAAI001086-10 Detection of Prions CAUGHEY, BYRON NIH $848,489
Transmissible Spongiform Encephalopathy (TSE) 2018 NIAID 1ZIAAI001105-10 Molecular Mechanisms of Prion Protein Amyloid Formation PRIOLA, SUZETTE NIH $126,209
Transmissible Spongiform Encephalopathy (TSE) 2018 NIAID 1ZIAAI001219-02 Prion protein function in redox homeostasis and associated failure in prion disease HAIGH, CATHRYN NIH $1,040,266
Transmissible Spongiform Encephalopathy (TSE) 2018 NHLBI 1ZIAHL000516-32 Role of molecular chaperones in protein folding diseases GREENE, LOIS NIH $1,090,045
Transmissible Spongiform Encephalopathy (TSE) 2018 NIAID 1ZIAAI001087-09 Prion Disease Therapeutics CAUGHEY, BYRON NIH $339,396


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