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Funding


RCDC

Project Listing by Category


Back to Estimates of Funding for Various Research, Condition, and Disease Categories (RCDC) Click the column headings to sort project listings.
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CategoryFYFunding ICProject NumberSub Project #Project TitlePI NameOrg NameState / CountryAmount
Gene Therapy Clinical Trials 2018 NHLBI 5R42HL099150-04 Lentiviral Vector for the treatment of Fanconi Anemia GOEBEL, WILLIAM RIMEDION, INC. CA $295,259
Gene Therapy Clinical Trials 2018 NCI 5R01CA211044-02 Off-the-shelf engineered NK cells for the treatment of AML REZVANI, KATY UNIVERSITY OF TX MD ANDERSON CAN CTR TX $366,000
Gene Therapy Clinical Trials 2018 NCI 5P30CA008748-52 7556 Gene Transfer RIVIERI, ISABELLE SLOAN-KETTERING INST CAN RESEARCH NY $369,891
Gene Therapy Clinical Trials 2018 NCI 5R01CA193140-03 Targeting the Ig-light chains with CAR-T cells in lymphoid tumors DOTTI, GIANPIETRO UNIV OF NORTH CAROLINA CHAPEL HILL NC $511,190
Gene Therapy Clinical Trials 2018 NHLBI 2T32HL092332-16 Training In Cell and Gene Therapy HESLOP, HELEN BAYLOR COLLEGE OF MEDICINE TX $353,720
Gene Therapy Clinical Trials 2018 NCI 2P50CA107399-11A1 5660 GMP Manufacturing KWAK, LARRY BECKMAN RESEARCH INSTITUTE/CITY OF HOPE CA $313,709
Gene Therapy Clinical Trials 2018 NCI 2P50CA107399-11A1 5661 CMV/CD19 bi-Specific CAR T cells combined with CMV vaccine as post-transplantation immunotherapy for non-Hodgkin lymphoma FORMAN, STEPHEN BECKMAN RESEARCH INSTITUTE/CITY OF HOPE CA $281,345
Gene Therapy Clinical Trials 2018 NHLBI 1R01HL140295-01 Clinical trial of AAV8-mediated FVIII gene transfer for hemophilia A DAVIDOFF, ANDREW ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $561,582
Gene Therapy Clinical Trials 2018 NCI 5R01CA200507-02 Optimizing Delivery of Oncolytic Measles Virus Strains with Cell Carriers GALANIS, EVANTHIA MAYO CLINIC ROCHESTER MN $592,664
Gene Therapy Clinical Trials 2018 NCI 5R01CA056821-24 Immunization Against Melanoma Differentiation Antigens WOLCHOK, JEDD SLOAN-KETTERING INST CAN RESEARCH NY $299,950
Gene Therapy Clinical Trials 2018 NCI 5R01CA217179-02 A Phase 1 Study of M032, a Genetically Engineered HSV-1 Expressing IL-12, in Patients with Recurrent/Progressive Glioblastoma Multiforme, Anaplastic Astrocytoma, or Gliosarcoma. MARKERT, JAMES UNIVERSITY OF ALABAMA AT BIRMINGHAM AL $559,312
Gene Therapy Clinical Trials 2018 NIAID 5U01AI131296-02 Therapeutic vaccination and PD-1 blockade in treated HIV disease DEEKS, STEVEN UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $1,370,393
Gene Therapy Clinical Trials 2018 NCI 5R01CA186730-04 Efficient Delivery of Plasmid DNA to Achieve Appropriate Transgene Expression HELLER, RICHARD OLD DOMINION UNIVERSITY VA $359,454
Gene Therapy Clinical Trials 2018 NEI 5U10EY023558-05 Leber's Hereditary Optic Neuropathy: Gene Therapy Clinical Trial GUY, JOHN UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $1
Gene Therapy Clinical Trials 2018 NEI 5U10EY024247-05 Biostatistics Center for Leber's Hereditary Optic Neuropathy: Gene Therapy Trial FEUER, WILLIAM UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $116,387
Gene Therapy Clinical Trials 2018 NCI 1U01CA224766-01 Protective Role of Nonclassical Monocytes in Immunotherapies for Solid Cancers HEDRICK, CATHERINE LA JOLLA INST FOR ALLERGY & IMMUNOLGY CA $418,320
Gene Therapy Clinical Trials 2018 NHLBI 5R01HL122267-03 CF Gene Therapy with adeno-associated viral vectors CEBOTARU, LIUDMILA JOHNS HOPKINS UNIVERSITY MD $723,820
Gene Therapy Clinical Trials 2018 NHLBI 5P01HL131471-03 7026 Clinical Trial and Immunologic aspects of muscle-directed rAAV1-AAT gene therapy FLOTTE, TERENCE UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $477,375
Gene Therapy Clinical Trials 2018 NCI 5R01CA196975-03 First in-human PET imaging studies of NIS reporter [18F]BF4 DEGRADO, TIMOTHY MAYO CLINIC ROCHESTER MN $172,718
Gene Therapy Clinical Trials 2018 NCI 1P01CA225622-01 8112 Project 1: Targeting cytomegalovirus antigens in glioblastoma with regulatory T cell depletion SAMPSON, JOHN DUKE UNIVERSITY NC $532,398
Gene Therapy Clinical Trials 2018 NCI 1P01CA225622-01 8116 Biostatistics and Bioinformatics Core HERNDON, JAMES DUKE UNIVERSITY NC $169,472
Gene Therapy Clinical Trials 2018 NCI 2P01CA018029-42A1 8718 Specific Adoptive Immunotherapy of AML with Engineered CD8+ T Cells GREENBERG, PHILIP FRED HUTCHINSON CANCER RESEARCH CENTER WA $838,209
Gene Therapy Clinical Trials 2018 NHLBI 1R01HL141781-01 Approach for in vivo gene delivery into hematopoietic stem cells for hemophilia A therapy LIEBER, ANDRE UNIVERSITY OF WASHINGTON WA $525,668
Gene Therapy Clinical Trials 2018 NINDS 1R01NS105986-01 Neurotrophin-3 gene therapy for Charcot-Marie-Tooth 1A SAHENK, ZARIFE RESEARCH INST NATIONWIDE CHILDREN'S HOSP OH $1,375,170
Gene Therapy Clinical Trials 2018 NCI 5R01CA114536-13 TARGETING ROR1 WITH CHIMERIC ANTIGEN RECEPTOR MODIFIED T CELLS RIDDELL, STANLEY FRED HUTCHINSON CANCER RESEARCH CENTER WA $458,731
Gene Therapy Clinical Trials 2018 NIDDK 5K23DK114564-02 Advancing Recognition and Personalized Genetic Medicine for MODY in a Multi-Ethnic US Population NAYLOR, ROCHELLE UNIVERSITY OF CHICAGO IL $186,976
Gene Therapy Clinical Trials 2018 NCI 5P50CA196510-03 8221 Project 4: Translation and preclinical studies of a personalized pancreas cancer vaccine GILLANDERS, WILLIAM WASHINGTON UNIVERSITY MO $503,987
Gene Therapy Clinical Trials 2018 NINDS 5R01NS094292-03 A Safety and Efficacy study of AAV2-hAADC for AADC deficiency BANKIEWICZ, KRYSTOF UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $493,460
Gene Therapy Clinical Trials 2018 NIAID 5U01AI125051-03 Gene therapy for SCID-X1 with low dose busulfan and a SIN-lentiviral vector PAI, SUNG-YUN BOSTON CHILDREN'S HOSPITAL MA $1,418,589
Gene Therapy Clinical Trials 2018 NIAID 5U01AI131310-02 Phase I therapeutic testing of viral-vectored vaccines that shift CD8+ T cell immunodominance to conserved regions of HIV-1 GOONETILLEKE, NILU UNIV OF NORTH CAROLINA CHAPEL HILL NC $1,169,548
Gene Therapy Clinical Trials 2018 NCI 1R01CA228232-01 Development of a Therapeutic for Brain Tumor Immunotherapy SAMPSON, JOHN DUKE UNIVERSITY NC $543,119
Gene Therapy Clinical Trials 2018 NHLBI 5UG1HL069315-18 MSKCC BMT CTN Renewal PERALES, MIGUEL-ANGEL SLOAN-KETTERING INST CAN RESEARCH NY $192,604
Gene Therapy Clinical Trials 2018 NHLBI 5UG1HL069286-18 Abramson Cancer Center BMT/CTN Core Clinical Center STADTMAUER, EDWARD UNIVERSITY OF PENNSYLVANIA PA $183,538
Gene Therapy Clinical Trials 2018 NHLBI 5UG1HL138641-02 Core Clinical Centers for the Blood and Marrow Transplant Clinical Trials Network HARI, PARAMESWARAN MEDICAL COLLEGE OF WISCONSIN WI $175,562
Gene Therapy Clinical Trials 2018 NCI 5R35CA210039-03 Immunoprevention and immunosurveillance of human non-viral cancers FINN, OLIVERA UNIVERSITY OF PITTSBURGH AT PITTSBURGH PA $819,666
Gene Therapy Clinical Trials 2018 NHLBI 5U01HL134812-03 Stem cells for therapeutics discovery in genetic blood disorders DALEY, GEORGE BOSTON CHILDREN'S HOSPITAL MA $1,264,005
Gene Therapy Clinical Trials 2018 NEI 1R01EY028601-01A1 Photoreceptor structure, function, and response to gene therapy in choroideremia MORGAN, JESSICA UNIVERSITY OF PENNSYLVANIA PA $402,500
Gene Therapy Clinical Trials 2018 NCATS 5U01TR001814-03 Disseminating Curative Biological Therapies for Rare Pediatric Diseases WILLIAMS, DAVID BOSTON CHILDREN'S HOSPITAL MA $1,340,745
Gene Therapy Clinical Trials 2018 NCI 5P50CA058236-23 5602 Tissue-Specific Radiation Sensitization of Prostate Cancer by Aptamer-Targeted siRNA Knock-Down of DNA Repair Pattiway LUPOLD, SHAWN JOHNS HOPKINS UNIVERSITY MD $212,898
Gene Therapy Clinical Trials 2018 NCI 5R01CA136551-10 Targeted therapy of B cell malignances with CAR-T cells of defined composition RIDDELL, STANLEY FRED HUTCHINSON CANCER RESEARCH CENTER WA $560,424
Gene Therapy Clinical Trials 2018 NCI 5R01CA175517-04 Efficacy of Dendritic Cell Vaccines Targeting CMV in Glioblastoma (phase 2 DC vaccine) MITCHELL, DUANE UNIVERSITY OF FLORIDA FL $703,160
Gene Therapy Clinical Trials 2018 NHLBI 5R01HL137848-02 Gene therapy targeting BCL11A to induce fetal hemoglobin and reduce sickle hemoglobin in patients with Sickle Cell Disease WILLIAMS, DAVID BOSTON CHILDREN'S HOSPITAL MA $1,582,593
Gene Therapy Clinical Trials 2018 NCATS 5U01AR071693-02 A Phase I Study of the Safety of AAV2/8 LSPhGAA in Late-onset Pompe Disease KOEBERL, DWIGHT DUKE UNIVERSITY NC $393,277
Gene Therapy Clinical Trials 2018 NIAMS 5U01AR071693-02 A Phase I Study of the Safety of AAV2/8 LSPhGAA in Late-onset Pompe Disease KOEBERL, DWIGHT DUKE UNIVERSITY NC $397,941
Gene Therapy Clinical Trials 2018 NINDS 5R01NS064607-10 OV therapy induced changes in tumor secretome and their impact on therapy KAUR, BALVEEN UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON TX $324,270
Gene Therapy Clinical Trials 2018 NCI 5P50CA192937-03 8323 Autologous CD19 Targeted 19-28z+ Tcells for the Treatment of Relapsed Diffuse Large B cell Lymphoma in Transplant Ineligible Elderly Patients BRENTJENS, RENIER SLOAN-KETTERING INST CAN RESEARCH NY $327,436
Gene Therapy Clinical Trials 2018 NCI 1P50CA221747-01A1 5142 Project 1: Neural Stem Cell Based Oncolytic Virotherapy of Malignant Glioma LESNIAK, MACIEJ NORTHWESTERN UNIVERSITY AT CHICAGO IL $255,555
Gene Therapy Clinical Trials 2018 NCI 1P01CA217805-01A1 5428 Project 1 - Clinical Trial HAAS, ANDREW UNIVERSITY OF PENNSYLVANIA PA $749,397
Gene Therapy Clinical Trials 2018 NCI 2P01CA163205-06A1 5803 Project 2: Clinical evaluation of a novel oHSV in recurrent human GBM CHIOCCA, E. BRIGHAM AND WOMEN'S HOSPITAL MA $339,665
Gene Therapy Clinical Trials 2018 NHLBI 2P01HL053749-21A1 5840 Lentiviral Gene Therapy and Genome Editing for X-linked Severe Combined Immunodeficiency SORRENTINO, BRIAN ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $590,189
Gene Therapy Clinical Trials 2018 NCI 1R01CA222903-01A1 Oncolytic Immunotherapy using Chimeric HSV C134: A Phase I Trial and Establishment of Response Indicators in Recurrent Glioma Patients MARKERT, JAMES UNIVERSITY OF ALABAMA AT BIRMINGHAM AL $586,155
Gene Therapy Clinical Trials 2018 NCATS 1U01TR002487-01 Accelerate cellular immunotherapy development for treatment of life-threatening childhood disorders PARK, JULIE SEATTLE CHILDREN'S HOSPITAL WA $1,478,374
Gene Therapy Clinical Trials 2018 NCI 1R01CA236615-01 Image-guided irreversible electroporation directed CAR T-cell delivery to solid tumors ADUSUMILLI, PRASAD SLOAN-KETTERING INST CAN RESEARCH NY $392,764
Gene Therapy Clinical Trials 2018 NCI 3P30CA008748-52S2 7556 Gene Transfer RIVIERI, ISABELLE SLOAN-KETTERING INST CAN RESEARCH NY $2,734
Gene Therapy Clinical Trials 2018 NCI 1R44CA233024-01 Clinical evaluation of combination oncolytic viro-immunotherapy for solid tumors DIAZ, ROSA VYRIAD, INC. MN $178,985
Gene Therapy Clinical Trials 2018 NCI 3P30CA008748-52S1 7556 Gene Transfer RIVIERI, ISABELLE SLOAN-KETTERING INST CAN RESEARCH NY $21,115
Gene Therapy Clinical Trials 2018 NIAID 5U19AI117950-04 5400 A PHASE I STUDY OF C34-CXCR4 MODIFIED CD4 T CELLS IN HIV-1 INFECTED INDIVIDUALS TEBAS, PABLO UNIVERSITY OF PENNSYLVANIA PA $551,880
Gene Therapy Clinical Trials 2018 NCI 261201200042I-5-26100006-1 PHASEI/II TRIAL OF A THERAPEUTIC DNA VACCINE FOR CHRONIC HEPATITIS C VIRUS (HCV) INFECTION; LIMBURG, PAUL MAYO CLINIC ROCHESTER MN $170,562
Gene Therapy Clinical Trials 2018 NCI 4R44CA221461-02 INTRAVESICAL ONCOLYTIC THERAPY FOR BLADDER CANCER DIAZ, ROSA VYRIAD, INC. MN $924,838
Gene Therapy Clinical Trials 2018 NIAAA 1U44AA027404-01 Development of an ALDH2-Targeting RNAi Therapeutic for Alcohol Use Disorders DUDEK, HENRYK DICERNA PHARMACEUTICALS, INC. MA $1,000,000
Gene Therapy Clinical Trials 2018 NCI 3P01CA214278-02S1 Enhancing Chimeric Antigen Receptor T Cell Therapies for Hematologic Malignancies: Beyond CART 19 JUNE, CARL UNIVERSITY OF PENNSYLVANIA PA $95,306
Gene Therapy Clinical Trials 2018 NINDS 3R01NS094292-02S1 A Safety and Efficacy study of AAV2-hAADC for AADC deficiency BANKIEWICZ, KRYSTOF UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $126,850
Gene Therapy Clinical Trials 2018 NCI 3P30CA008748-52S3 7556 Gene Transfer RIVIERI, ISABELLE SLOAN-KETTERING INST CAN RESEARCH NY $4,924
Gene Therapy Clinical Trials 2018 NCI 3P30CA008748-52S4 7556 Gene Transfer RIVIERI, ISABELLE SLOAN-KETTERING INST CAN RESEARCH NY $13,274
Gene Therapy Clinical Trials 2018 NCI 1ZIABC010350-19 Prevention of AIDS FELBER, BARBARA NIH $1,083,056
Gene Therapy Clinical Trials 2018 NCI 1ZIABC011415-08 Allogeneic T cells Transduced with an Anti-CD19 Chimeric Antigen Receptor KOCHENDERFER, JAMES NIH $26,928
Gene Therapy Clinical Trials 2018 NCI 1ZIASC004002-49 IL-2:IL-15 cytokine receptor: implications for cancer therapy and vaccine WALDMANN, THOMAS NIH $1,545,717
Gene Therapy Clinical Trials 2018 NCI 1ZICBC011029-11 Preclinical development and clinical monitoring of adoptive immune therapy ROSE, JEREMY NIH $513,266
Gene Therapy Clinical Trials 2018 NINDS 3R01NS094292-03S1 A Safety and Efficacy study of AAV2-hAADC for AADC deficiency BANKIEWICZ, KRYSTOF UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $138,563
Gene Therapy Clinical Trials 2018 NIAID 1ZIAAI000645-27 Clinical Diagnostic Studies and Treatment of Patients with Immune Deficiencies DE RAVIN, SUK NIH $754,824
Gene Therapy Clinical Trials 2018 NIAID 1ZIAAI000991-12 Gene Therapy Clinical Trials for Chronic Granulomatous Disease KANG, ELIZABETH NIH $377,412
Gene Therapy Clinical Trials 2018 NIAID 1ZIAAI000992-12 Gene Therapy Clinical Trials for X-linked Severe Combined Immunodeficiency DE RAVIN, SUK NIH $1,260,535
Gene Therapy Clinical Trials 2018 NICHD 1ZIAHD008927-07 Choroid plexus-mediated gene therapy for lysosomal storage disorders KALER, STEPHEN NIH $254,023
Gene Therapy Clinical Trials 2018 NIAID 1ZIAAI005035-17 HIV Preventive Vaccine and Monoclonal Antibody Studies LEDGERWOOD, JULIE NIH $6,244,013
Gene Therapy Clinical Trials 2018 NIAID 1ZIAAI005047-16 Biodefense/Emerging Infection Vaccine Studies LEDGERWOOD, JULIE NIH $7,568,442


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