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RCDC

Project Listing by Category


Back to Estimates of Funding for Various Research, Condition, and Disease Categories (RCDC) Click the column headings to sort project listings.
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CategoryFYFunding ICProject NumberSub Project #Project TitlePI NameOrg NameState / CountryAmount
Childhood Leukemia 2018 NCI 1K22CA214849-01 The role of the histone chaperone Chaf1b in sustaining the Hoxa9-driven AML differentiation block BLANCO, MARIO UNIVERSITY OF PENNSYLVANIA PA $191,970
Childhood Leukemia 2018 NCI 5R01CA132640-17 Role of heat shock factors (Hsfs) in tumorigenesis MIVECHI, NAHID AUGUSTA UNIVERSITY GA $270,000
Childhood Leukemia 2018 NCI 5R01CA190964-04 Role of IKAROS in the Biology and Therapy of High-Risk Precursor B-Cell Leukemia VAN ETTEN, RICHARD UNIVERSITY OF CALIFORNIA-IRVINE CA $544,106
Childhood Leukemia 2018 NCI 5R01CA194058-03 Painted erythrocyte carriers for therapy of acute myeloid leukemia SIMBERG, DIMITRI UNIVERSITY OF COLORADO DENVER CO $352,151
Childhood Leukemia 2018 NCI 5R01CA201230-04 The role of H3K79 methylation in IDH-mutant leukemia BERNT, KATHRIN CHILDREN'S HOSP OF PHILADELPHIA PA $438,616
Childhood Leukemia 2018 NCI 5R01CA185301-04 Enhancing NK Cell Activity by Dietary Diphyllin Lignans for Cancer Prevention YU, JIANHUA OHIO STATE UNIVERSITY OH $352,275
Childhood Leukemia 2018 NCI 5R00CA181500-05 The Role of Protein Tyrosine Phosphate PRL3 in Leukemia Development BLACKBURN, JESSICA UNIVERSITY OF KENTUCKY KY $248,999
Childhood Leukemia 2018 NCI 5R01CA174683-05 Comprehensive Approach to Improve Medicine Adherence in Pediatric Leukmia BHATIA, SMITA UNIVERSITY OF ALABAMA AT BIRMINGHAM AL $597,219
Childhood Leukemia 2018 NCI 5R01CA090668-15 FLT3 Tyrosine Kinase Inhibitors as Therapy for Leukemia SMALL, DONALD JOHNS HOPKINS UNIVERSITY MD $291,600
Childhood Leukemia 2018 NCI 5R01CA195519-03 Image-guided irradiation safely intensifies HSCT regimen for refractory leukemia FORMAN, STEPHEN BECKMAN RESEARCH INSTITUTE/CITY OF HOPE CA $238,425
Childhood Leukemia 2018 NCI 5R01CA201184-03 Biologic and Therapeutic Significance of miR-155 in AML MARCUCCI, GUIDO BECKMAN RESEARCH INSTITUTE/CITY OF HOPE CA $549,553
Childhood Leukemia 2018 NCI 5R01CA158073-07 The Role of ATM in Suppression of Lymphomas ZHA, SHAN COLUMBIA UNIVERSITY HEALTH SCIENCES NY $380,000
Childhood Leukemia 2018 NCI 5R01CA172408-05 Role of Asxl1 in normal hematopoiesis and pathogenesis of myeloid malignancies YANG, FENG-CHUN UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $318,513
Childhood Leukemia 2018 NCI 5R01CA204979-02 Mechanisms of inv(16) acute myeloid leukemia CASTILLA, LUCIO UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $436,263
Childhood Leukemia 2018 NICHD 5R21HD087760-02 Targeting SHP2 phosphatase for chemoprevention of leukemic progression in Noonan syndrome QU, CHENG-KUI EMORY UNIVERSITY GA $234,000
Childhood Leukemia 2018 NCI 5R01CA211711-02 APPLYING ERROR-CORRECTED SEQUENCING TO DETECT MINIMAL RESIDUAL IN THE AAML 1031 STUDY DRULEY, TODD WASHINGTON UNIVERSITY MO $352,587
Childhood Leukemia 2018 NCI 5R01CA212649-02 Personalized vaccine for patients with AML AVIGAN, DAVID BETH ISRAEL DEACONESS MEDICAL CENTER MA $721,179
Childhood Leukemia 2018 NCI 5R01CA169784-05 Genetic Dissection of Acute Myeloid Leukemia. AIFANTIS, IANNIS NEW YORK UNIVERSITY SCHOOL OF MEDICINE NY $355,993
Childhood Leukemia 2018 NHLBI 5K08HL135434-02 Targeting SETBP1 in Myeloproliferative Disorders STIEGLITZ, ELLIOT UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $179,928
Childhood Leukemia 2018 NCI 5R01CA142874-08 Targeting PML for Leukemia Therapy PANDOLFI, PIER PAOLO BETH ISRAEL DEACONESS MEDICAL CENTER MA $457,619
Childhood Leukemia 2018 NCI 5R01CA142665-08 Glucocorticoids in Lymphoblastic Leukemia RELLING, MARY ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $487,994
Childhood Leukemia 2018 NCI 5R01CA211044-02 Off-the-shelf engineered NK cells for the treatment of AML REZVANI, KATY UNIVERSITY OF TX MD ANDERSON CAN CTR TX $366,000
Childhood Leukemia 2018 NCI 5P30CA006516-53 5399 Program 4: Leukemia EBERT, BENJAMIN BRIGHAM AND WOMEN'S HOSPITAL MA $74,743
Childhood Leukemia 2018 NHLBI 5R01HL130034-03 The Cebpa Enhancer in Normal Hematopoiesis and Progression to AML FRIEDMAN, ALAN JOHNS HOPKINS UNIVERSITY MD $405,000
Childhood Leukemia 2018 NHLBI 5R01HL117976-05 Epithelial mechanisms of inducible resistance to AML-associated pneumonia EVANS, SCOTT UNIVERSITY OF TX MD ANDERSON CAN CTR TX $400,000
Childhood Leukemia 2018 NIGMS 5R01GM118578-02 Genetics-guided Individualization of Thiopurine Therapy YANG, JUN ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $558,496
Childhood Leukemia 2018 NCI 5R35CA197695-02 Translating genomic discoveries to improved outcomes for high risk acute leukemia MULLIGHAN, CHARLES ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $1,077,000
Childhood Leukemia 2018 NCI 5R01CA192924-04 CSF2 receptor mediated actions in t(8;21) leukemia ZHANG, DONG-ER UNIVERSITY OF CALIFORNIA, SAN DIEGO CA $342,403
Childhood Leukemia 2018 NCI 5K08CA181340-05 Targeting Chromatin Modifications in Leukemia with Trisomy 21 LANE, ANDREW DANA-FARBER CANCER INST MA $128,526
Childhood Leukemia 2018 NIGMS 1P20GM121322-01A1 8733 Immunometabolic regulation of leukemic niche-donor cell interaction DU, WEI WEST VIRGINIA UNIVERSITY WV $255,080
Childhood Leukemia 2018 NCI 2P01CA013106-46A1 5085 Project 4: Transcriptional Coactivators and Enhancers in Human Cancer VAKOC, CHRISTOPHER COLD SPRING HARBOR LABORATORY NY $553,842
Childhood Leukemia 2018 NCI 5R01CA201225-03 Leukemia Specific Splice Isoforms as Neo-Antigens for T-Cell Immunotherapy ARMISTEAD, PAUL UNIV OF NORTH CAROLINA CHAPEL HILL NC $490,809
Childhood Leukemia 2018 NCI 2P50CA107399-11A1 5662 Therapy-related leukemia following autologous transplantation for lymphoma BHATIA, SMITA BECKMAN RESEARCH INSTITUTE/CITY OF HOPE CA $676,409
Childhood Leukemia 2018 NIEHS 5U13ES026496-03 Childhood Leukemia International Consortium Scientific Annual Meetings METAYER, CATHERINE UNIVERSITY OF CALIFORNIA BERKELEY CA $15,000
Childhood Leukemia 2018 NCI 5F30CA213878-02 Co-Evolution of the CD8+ T Cell Repertoire and AML In the Setting of Immunotherapy GEORGE, JASON RICE UNIVERSITY TX $49,524
Childhood Leukemia 2018 NCI 1R01CA222590-01 Developing a novel therapeutic strategy for overcoming TKI resistance in ALL LI, SHAOGUANG UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $487,847
Childhood Leukemia 2018 NCI 1R01CA222349-01 Non-canonical Caspase-8 Activation on Autophagosomal Membranes WANG, HONG-GANG PENNSYLVANIA STATE UNIV HERSHEY MED CTR PA $348,696
Childhood Leukemia 2018 NHLBI 5R01HL136504-02 TEMPORAL CHANGES IN MECHANISMS OF HSC SELF-RENEWAL AND MYELOID LEUKEMOGENESIS MAGEE, JEFFREY WASHINGTON UNIVERSITY MO $381,250
Childhood Leukemia 2018 NCI 1K08CA222699-01 Targeting MerTK as an immunotherapeutic strategy in acute myeloid leukemia LEE SHERICK, ALISA UNIVERSITY OF COLORADO DENVER CO $175,285
Childhood Leukemia 2018 NCI 1K08CA222684-01 Targeting mitochondrial one carbon folate metabolism for novel T-cell acute lymphoblastic leukemia therapy PIKMAN, YANA DANA-FARBER CANCER INST MA $177,120
Childhood Leukemia 2018 NHLBI 1K08HL140138-01 Investigating the Mechanisms of Cohesinopathy in Myelodysplastic Syndromes TOTHOVA, ZUZANA DANA-FARBER CANCER INST MA $171,720
Childhood Leukemia 2018 NCI 5R01CA213131-02 Targeting Transcriptional Regulators for Immunotherapy of Acute Myeloid Leukemia KORTYLEWSKI, MARCIN BECKMAN RESEARCH INSTITUTE/CITY OF HOPE CA $430,377
Childhood Leukemia 2018 NCI 5R01CA076167-15 Genetic Analysis of Myeloproliferative Disease COWELL, JOHN AUGUSTA UNIVERSITY GA $307,800
Childhood Leukemia 2018 NIGMS 1R01GM126363-01 Mechanistic Studies of Type II Topoisomerases and Topoisomerase-Targeted Agents OSHEROFF, NEIL VANDERBILT UNIVERSITY TN $302,225
Childhood Leukemia 2018 NCI 5K08CA201591-02 Targeting the ARHGAP25 pathway in acute myelogenous leukemia stem cells WANG, LEO BECKMAN RESEARCH INSTITUTE/CITY OF HOPE CA $169,560
Childhood Leukemia 2018 NCI 1R21CA223439-01 Targeting MCJ/DNAJC15 and the mitochondrial electron transport chain in acute myeloid leukemia DEGREGORI, JAMES UNIVERSITY OF COLORADO DENVER CO $163,459
Childhood Leukemia 2018 NCI 1R21CA209298-01A1 A novel genetic pathway for survival of B-lymphoblastic leukemia-initiating cells LI, SHAOGUANG UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $218,588
Childhood Leukemia 2018 NCI 5R01CA151898-08 CRLF2 signaling in B-cell acute lymphoblastic leukemia WEINSTOCK, DAVID DANA-FARBER CANCER INST MA $392,969
Childhood Leukemia 2018 NCI 5P30CA021765-39 6702 Hematalogical Malignancies GILBERTSON, RICHARD ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $695,190
Childhood Leukemia 2018 NCI 5P30CA021765-39 6709 Early Phase Clinical Research Support GILBERTSON, RICHARD ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $256,190
Childhood Leukemia 2018 NCI 5P30CA021765-39 6716 Transdisciplinary Collaboration and Coordination GILBERTSON, RICHARD ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $319,532
Childhood Leukemia 2018 NCI 5R01CA195642-04 Triad1 regulates myelopoiesis and functions as a leukemia suppressor EKLUND, ELIZABETH NORTHWESTERN UNIVERSITY AT CHICAGO IL $353,419
Childhood Leukemia 2018 NCI 5R44CA213595-02 Rapid detection of minimal residual disease in acute myeloid leukemia from peripheral blood MULLER, ROLF BIOFLUIDICA, INC NC $712,071
Childhood Leukemia 2018 NCI 5K99CA207731-02 Discovery of Synthetic Lethal Targets for Recurrent Epigenetic Mutations in Acute Myeloid Leukemia THOMAS, DANIEL STANFORD UNIVERSITY CA $173,448
Childhood Leukemia 2018 NCI 5R01CA188520-04 Genome maintenance by Hdacs1,2 and their inhibition for Pre-B leukemia therapy BHASKARA, SRIVIDYA UNIVERSITY OF UTAH UT $340,838
Childhood Leukemia 2018 NCI 5R01CA194057-04 Metabolic pathways in leukemia SCHUETZ, JOHN ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $410,606
Childhood Leukemia 2018 NCI 5R01CA190843-04 A Label-Free, Point-of-Care Platform to Diagnose Acute Promyelocytic Leukemia SOHN, LYDIA UNIVERSITY OF CALIFORNIA BERKELEY CA $311,458
Childhood Leukemia 2018 NCI 1R03CA223730-01 Genetic underpinnings of ethnic disparities in bone toxicities between Hispanic and non-Hispanic children treated for acute lymphoblastic leukemia YAO, SONG ROSWELL PARK CANCER INSTITUTE CORP NY $87,050
Childhood Leukemia 2018 NCI 5R01CA178454-07 The role and functional mechanism of TET1 in MLL-rearranged leukemia CHEN, JIANJUN BECKMAN RESEARCH INSTITUTE/CITY OF HOPE CA $369,725
Childhood Leukemia 2018 NCI 7R01CA211963-02 Ionizing radiation induced hematological malignancies ZHOU, DAOHONG UNIVERSITY OF FLORIDA FL $368,866
Childhood Leukemia 2018 NCI 5R01CA215504-02 Instructive role of MLL fusion proteins in lineage determination and leukemogenesis THIRMAN, MICHAEL UNIVERSITY OF CHICAGO IL $594,545
Childhood Leukemia 2018 NCI 5R21CA216551-02 Targeting DNA Base Excision Repair in Acute Myeloid Leukemias LLOYD, R. OREGON HEALTH & SCIENCE UNIVERSITY OR $167,475
Childhood Leukemia 2018 NCI 5R01CA152108-07 Molecular and Cellular Mechanisms of Chronic Myelomonocytic Leukemia (CMML) ZHANG, JING UNIVERSITY OF WISCONSIN-MADISON WI $373,634
Childhood Leukemia 2018 NHLBI 5R01HL117737-19 Microchimerism as AlloImmunity NELSON, J. FRED HUTCHINSON CANCER RESEARCH CENTER WA $443,085
Childhood Leukemia 2018 NCI 2R01CA163086-06A1 Function and targeting of a stable transcription factor complex in leukemia ROEDER, ROBERT ROCKEFELLER UNIVERSITY NY $387,731
Childhood Leukemia 2018 NCI 1R01CA215059-01A1 The Role of DLST in Leukemogenesis FENG, HUI BOSTON UNIVERSITY MEDICAL CAMPUS MA $377,437
Childhood Leukemia 2018 NCI 5R01CA193842-04 Characterizing MSI2 in leukemia KHARAS, MICHAEL SLOAN-KETTERING INST CAN RESEARCH NY $414,827
Childhood Leukemia 2018 NCI 5K08CA201611-02 DEFINING THE ROLE OF DOT1L IN DNMT3A-MUTANT LEUKEMIA RAU, RACHEL BAYLOR COLLEGE OF MEDICINE TX $162,148
Childhood Leukemia 2018 NCI 5K08CA201640-02 Developing differentiation therapy for the treatment of patients with acute myeloid leukemia SYKES, DAVID MASSACHUSETTS GENERAL HOSPITAL MA $169,268
Childhood Leukemia 2018 NCI 5R01CA207086-02 Mechanisms of KLF4 suppression in pediatric leukemia LACORAZZA, DANIEL BAYLOR COLLEGE OF MEDICINE TX $370,641
Childhood Leukemia 2018 NCI 5R01CA193235-04 Metabolic Regulation in Leukemia-Initatiating Cells NAKADA, DAISUKE BAYLOR COLLEGE OF MEDICINE TX $462,191
Childhood Leukemia 2018 NCI 5R01CA101774-16 Mechanisms of Leukemogenesis in Down Syndrome CRISPINO, JOHN NORTHWESTERN UNIVERSITY AT CHICAGO IL $337,725
Childhood Leukemia 2018 NCI 5R01CA190661-03 Novel Biomarkers to Risk-Stratify AML Patients with NPM1^Pos/FLT3-IT^Neg Genotype STIREWALT, DEREK FRED HUTCHINSON CANCER RESEARCH CENTER WA $580,264
Childhood Leukemia 2018 NCI 5K08CA204734-03 Determining the Role of BCOR Mutations in Myeloid Malignancies LINDSLEY, ROBERT DANA-FARBER CANCER INST MA $176,970
Childhood Leukemia 2018 NCI 5UM1CA183730-05 Collaborative Human Tissue Network (CHTN) RAMIREZ MILAN, NILSA RESEARCH INST NATIONWIDE CHILDREN'S HOSP OH $769,787
Childhood Leukemia 2018 NCI 5F30CA217006-02 Analysis of the novel phenomenon of antibody-mediated fratricide in Acute Myeloid Leukemia FATEHCHAND, KAVIN OHIO STATE UNIVERSITY OH $49,524
Childhood Leukemia 2018 NCI 5R01CA176803-04 Targeted- and timed-releasing nanotherapeutics against leukemia stem cells PAN, CHONG-XIAN UNIVERSITY OF CALIFORNIA AT DAVIS CA $359,138
Childhood Leukemia 2018 NIGMS 5F31GM116569-03 Developing an Artemis Nuclease Inhibitor to Potentially Treat Acute Lymphoblastic Leukemia ESGUERRA, ZITADEL ANNE UNIVERSITY OF SOUTHERN CALIFORNIA CA $43,166
Childhood Leukemia 2018 NCI 5R01CA133379-10 The role of the SCF/FBW7 ubiquitin ligase complex in hematopiesis and leukemia. AIFANTIS, IANNIS NEW YORK UNIVERSITY SCHOOL OF MEDICINE NY $381,375
Childhood Leukemia 2018 NCI 5R01CA214965-03 The role and mechanism of FTO in leukemogenesis and drug response CHEN, JIANJUN BECKMAN RESEARCH INSTITUTE/CITY OF HOPE CA $444,571
Childhood Leukemia 2018 NCI 5U10CA180886-05 COG NCTN Network Group Operations Center ADAMSON, PETER CHILDREN'S HOSP OF PHILADELPHIA PA $20,853,800
Childhood Leukemia 2018 NCI 5R01CA201235-02 Targeting the GFI1-LSD1 Axis in T-Cell Acute Lymphoblastic Leukemia ENGEL, MICHAEL UNIVERSITY OF UTAH UT $348,273
Childhood Leukemia 2018 NCI 5R01CA217092-02 Mechanisms of Formation and Progression of Preleukemic Stem Cells STEIDL, ULRICH ALBERT EINSTEIN COLLEGE OF MEDICINE, INC NY $397,371
Childhood Leukemia 2018 NCI 1R01CA215518-01A1 Targeting the Notch:Myc axis in leukemia/lymphoma PEAR, WARREN UNIVERSITY OF PENNSYLVANIA PA $468,293
Childhood Leukemia 2018 NCI 5K12CA090433-17 Pediatric Oncology Clinical Research Training Program BLANEY, SUSAN BAYLOR COLLEGE OF MEDICINE TX $827,164
Childhood Leukemia 2018 NCI 5R01CA201496-03 Novel RNA-Directed Therapy for the Treatment of Acute Myeloid Leukemia ROSEN, STEVEN BECKMAN RESEARCH INSTITUTE/CITY OF HOPE CA $479,954
Childhood Leukemia 2018 NHLBI 5F30HL132613-04 Characterizing the Novel Protein C15orf65 HOWE, RUTH ALBERT EINSTEIN COLLEGE OF MEDICINE, INC NY $49,524
Childhood Leukemia 2018 NHLBI 5R01HL131444-03 The role of EVI1-induced hypermethylation in leukemogenesis. QIAN, ZHIJIAN UNIVERSITY OF ILLINOIS AT CHICAGO IL $399,750
Childhood Leukemia 2018 NCI 1R01CA225231-01 Identification of therapeutic targets for leukemia stem cells in AML-iPSC models PAPAPETROU, EIRINI ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI NY $625,414
Childhood Leukemia 2018 NCI 5R01CA206210-03 Therapeutic targeting of glutamine metabolism in MDS KONOPLEVA, MARINA UNIVERSITY OF TX MD ANDERSON CAN CTR TX $496,810
Childhood Leukemia 2018 NCI 5R01CA211996-02 Dexrazoxane and Prevention of Anthracycline-Related Cardiomyopathy CHOW, ERIC FRED HUTCHINSON CANCER RESEARCH CENTER WA $646,503
Childhood Leukemia 2018 NHLBI 5K08HL136894-02 Hedgehog Signaling in the Progression of Myelodysplastic Syndromes GONDEK, LUKASZ JOHNS HOPKINS UNIVERSITY MD $171,720
Childhood Leukemia 2018 NCI 1R41CA224830-01 Preclinical studies of Selective and Orally Bioavailable Aurora B Inhibitors for the Treatment of AML LI, HONG YU SYNACTIX PHARMACEUTICALS, INC. AZ $299,975
Childhood Leukemia 2018 NHLBI 1F31HL137310-01A1 The TIFAB-USP15 Complex in the Pathogenesis of MDS and AML NIEDERKORN, MADELINE UNIVERSITY OF CINCINNATI OH $32,864
Childhood Leukemia 2018 NHLBI 5K08HL127269-04 Bone Marrow Microenvironmental Expression of Cytochrome P450 Enzymes GHIAUR, GABRIEL JOHNS HOPKINS UNIVERSITY MD $171,720
Childhood Leukemia 2018 NHLBI 5R01HL128173-04 Multiscale Modeling of Myelodysplastic Syndromes COREY, SETH VIRGINIA COMMONWEALTH UNIVERSITY VA $713,684
Childhood Leukemia 2018 NCI 5R01CA098571-14 Molecular Mechanisms of eIF4E mediated transformation BORDEN, KATHERINE UNIVERSITY OF MONTREAL CANADA $227,057
Childhood Leukemia 2018 NCI 5R01CA197991-03 Determining the Role of Metabolism in Resistance in Acute Myeloid Leukemia PARDEE, TIMOTHY WAKE FOREST UNIVERSITY HEALTH SCIENCES NC $354,563
Childhood Leukemia 2018 NCI 5R01CA173852-05 Role of p21 activated kinase in Leukemogenesis KAPUR, REUBEN INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS IN $323,700
Childhood Leukemia 2018 NCI 5U01CA176063-05 ARID5B and disparities of childhood leukemia YANG, JUN ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $368,510
Childhood Leukemia 2018 NCI 5R01CA172443-05 Targeting NEDD8-Mediated Protein Turnover in AML CAREW, JENNIFER UNIVERSITY OF ARIZONA AZ $286,661
Childhood Leukemia 2018 NCI 5R01CA175353-05 Deep sequencing for minimal residual disease detection in Acute Lymphoblastic Leu ROBINS, HARLAN FRED HUTCHINSON CANCER RESEARCH CENTER WA $544,480
Childhood Leukemia 2018 NCI 5R01CA178030-05 Regulation of transcription and tumor suppression by MTG family members HIEBERT, SCOTT VANDERBILT UNIVERSITY TN $364,000
Childhood Leukemia 2018 NCI 5R01CA194923-04 Long non-coding RNAs in hematopoiesis and blood malignancy AIFANTIS, IANNIS NEW YORK UNIVERSITY SCHOOL OF MEDICINE NY $457,533
Childhood Leukemia 2018 NCI 5R21CA208937-02 Mechanism-based approach to combine histone deacetylase inhibitors with PARP inhibitors for therapy in AML RASSOOL, FEYRUZ UNIVERSITY OF MARYLAND BALTIMORE MD $168,019
Childhood Leukemia 2018 NCI 5R01CA193776-04 Improving risk allocation and developing novel therapies for children with T-ALL TEACHEY, DAVID CHILDREN'S HOSP OF PHILADELPHIA PA $594,741
Childhood Leukemia 2018 NCI 5U54CA193419-04 7381 Project 2: Molecular Modulation of Chromatin and Nuclear Structure in Cancer LICHT, JONATHAN NORTHWESTERN UNIVERSITY AT CHICAGO IL $677,567
Childhood Leukemia 2018 NCI 5R01CA132946-11 Pharmacogenomics of Ara-C in AML LAMBA, JATINDER UNIVERSITY OF FLORIDA FL $310,602
Childhood Leukemia 2018 NCI 5R01CA175761-05 Function of the PR domain of the MDSI-EVI1 in MLL fusion protein leukemogenesis PERKINS, ARCHIBALD UNIVERSITY OF ROCHESTER NY $318,513
Childhood Leukemia 2018 NCI 5F31CA217140-02 Novel mechanisms and therapeutic strategies of refractory leukemia MELGAR, KATELYN CINCINNATI CHILDRENS HOSP MED CTR OH $37,204
Childhood Leukemia 2018 NCI 5U54CA193461-04 7298 Project 1: Clonal Dynamics Guiding Curative Therapies for Acute Myeloid Leukemia SCADDEN, DAVID MASSACHUSETTS GENERAL HOSPITAL MA $366,060
Childhood Leukemia 2018 NCI 2P50CA100632-16 7425 Project 2: Anti-PR1 Immune Therapy for Myeloid Leukemia MOLLDREM, JEFFREY UNIVERSITY OF TX MD ANDERSON CAN CTR TX $238,193
Childhood Leukemia 2018 NCI 2P50CA100632-16 7427 Project 4: Off-the-shelf engineered cord blood-derived natural killer cells for the treatment acute lymphoblastic leukemia REZVANI, KATY UNIVERSITY OF TX MD ANDERSON CAN CTR TX $238,194
Childhood Leukemia 2018 NCI 2P50CA100632-16 7428 Project 5: Targeting Oxidative Phosphorylation in AML DRAETTA, GIULIO UNIVERSITY OF TX MD ANDERSON CAN CTR TX $215,115
Childhood Leukemia 2018 NCI 5R01CA185058-05 Impact of low IL-10 levels at birth and leukemia risk KOGAN, SCOTT UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $602,331
Childhood Leukemia 2018 NCI 5R01CA064140-25 Role of AML1-ETO in Acute Leukemia HIEBERT, SCOTT VANDERBILT UNIVERSITY TN $353,250
Childhood Leukemia 2018 NCI 5R01CA185687-04 Risk of Pediatric and Adolescent Cancer Associated with Medical Imaging SMITH-BINDMAN, REBECCA UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $2,139,085
Childhood Leukemia 2018 NCI 5R01CA190509-04 The function of cyclin C in tumorigenesis SICINSKI, PETER DANA-FARBER CANCER INST MA $453,569
Childhood Leukemia 2018 NCI 5R01CA216352-02 In Vivo Functional Analysis of Chromosome 7q22 Deletions in Myeloid Malignancies SHANNON, KEVIN UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $338,672
Childhood Leukemia 2018 NCI 7R01CA182284-06 Pathophysiology of Chemotherapy-Induced Cognitive Deficits in Juvenile Rats COLE, PETER RBHS -CANCER INSTITUTE OF NEW JERSEY NJ $329,925
Childhood Leukemia 2018 NCI 5R25CA183725-04 Problem-Solving Skills Training for Clinicians Providing Psychosocial Care in Pediatric Oncology SAHLER, OLLE JANE UNIVERSITY OF ROCHESTER NY $257,991
Childhood Leukemia 2018 NCI 5R01CA188269-05 Developing CRM1 inhibitors in AML GARZON, RAMIRO OHIO STATE UNIVERSITY OH $319,550
Childhood Leukemia 2018 NCI 5F30CA203292-04 Chromatin dysregulation generated by recurrent point mutation in histone methyltransferase, MMSET, drives progression of lymphoid malignancies SWAROOP, ALOK NORTHWESTERN UNIVERSITY AT CHICAGO IL $49,524
Childhood Leukemia 2018 NCI 2P01CA018029-42A1 8718 Specific Adoptive Immunotherapy of AML with Engineered CD8+ T Cells GREENBERG, PHILIP FRED HUTCHINSON CANCER RESEARCH CENTER WA $838,209
Childhood Leukemia 2018 NCI 5R01CA216421-02 The cohesin complex as a tumor suppressor in myeloid leukemia AIFANTIS, IANNIS NEW YORK UNIVERSITY SCHOOL OF MEDICINE NY $511,640
Childhood Leukemia 2018 NCI 5R01CA213138-02 CD25-mediated feedback control of BCR-signaling and its oncogenic mimics MÜSCHEN, MARKUS BECKMAN RESEARCH INSTITUTE/CITY OF HOPE CA $395,738
Childhood Leukemia 2018 NCI 5R01CA213062-02 Molecular mechanisms of Nutrient sensing in cancer HAIGIS, MARCIA HARVARD MEDICAL SCHOOL MA $374,242
Childhood Leukemia 2018 NCI 5K99CA212302-02 Resistance To Targeted Immunotherapies:CART19 as a Paradigm RUELLA, MARCO UNIVERSITY OF PENNSYLVANIA PA $174,096
Childhood Leukemia 2018 NCI 1R37CA227656-01 The phosphatase PRL3 as a MYC target and pro-survival oncogene in Acute Lymphoblastic Leukemia BLACKBURN, JESSICA UNIVERSITY OF KENTUCKY KY $349,988
Childhood Leukemia 2018 NCI 5R01CA216815-02 Improving the disposition of antileukemic asparaginase after drug-induced immunotoxicity FERNANDEZ, CHRISTIAN UNIVERSITY OF PITTSBURGH AT PITTSBURGH PA $322,023
Childhood Leukemia 2018 NCI 5U01CA214116-02 Proteogenomic Translational Research Center for Clinical Proteomic RODLAND, KARIN BATTELLE PACIFIC NORTHWEST LABORATORIES WA $1,372,508
Childhood Leukemia 2018 NCI 5R01CA213912-02 Targeting CK2 oncogenic pathway to overcome drug resistance in high-risk leukemia DOVAT, SINISA PENNSYLVANIA STATE UNIV HERSHEY MED CTR PA $353,876
Childhood Leukemia 2018 NHLBI 5F31HL136107-02 Function of the Ubiquitin-Specific Peptidase 22 (USP22) in Acute Myeloid Leukemia MELO CARDENAS, SINDEY NORTHWESTERN UNIVERSITY AT CHICAGO IL $38,735
Childhood Leukemia 2018 NIGMS 5P50GM115279-04 7544 CPML - Core A: Administrative Core RELLING, MARY ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $212,409
Childhood Leukemia 2018 NIGMS 5P50GM115279-04 7545 CPML - Core B: Cell & Molecular Core CREWS, KRISTINE ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $361,615
Childhood Leukemia 2018 NIGMS 5P50GM115279-04 7546 CPML - Core C: Bioinformatics & Biostatistical Core ZHANG, JINGHUI ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $620,755
Childhood Leukemia 2018 NIGMS 5P50GM115279-04 7547 CPML - Project 1: Genome-wide Studies of ALL Response MULLIGHAN, CHARLES ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $731,795
Childhood Leukemia 2018 NIGMS 5P50GM115279-04 7548 CPML - Project 2: Genome-wide Studies of ALL Drug Sensitivity EVANS, WILLIAM ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $729,420
Childhood Leukemia 2018 NIGMS 5P50GM115279-04 7549 CPML - Project 3: Genome-wide Studies of Adverse Effects RELLING, MARY ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $384,126
Childhood Leukemia 2018 NCI 5R01CA198089-04 Understanding and Targeting Chemotherapy Resistance in Acute Myeloid Leukemia CARROLL, MARTIN UNIVERSITY OF PENNSYLVANIA PA $663,135
Childhood Leukemia 2018 NCI 5R01CA194206-03 Transporters and hematopoietic toxicity SCHUETZ, JOHN ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $484,566
Childhood Leukemia 2018 NCI 5K08CA194256-04 Chimeric Antigen Receptor T cell Therapy for Acute Myeloid Leukemia (AML) GILL, SAAR UNIVERSITY OF PENNSYLVANIA PA $167,832
Childhood Leukemia 2018 NCI 5R01CA057138-27 Employing the Myc Transcriptional Network to Reveal Oncogenic Pathways EISENMAN, ROBERT FRED HUTCHINSON CANCER RESEARCH CENTER WA $635,460
Childhood Leukemia 2018 NCI 5K08CA181507-03 Analysis of TET2 function in acute leukemia SHIH, ALAN SLOAN-KETTERING INST CAN RESEARCH NY $180,036
Childhood Leukemia 2018 NCI 5K08CA191091-04 Epigenetic mechanisms of drug resistance in T-cell acute lymphoblastic leukemia KNOECHEL, BIRGIT DANA-FARBER CANCER INST MA $177,120
Childhood Leukemia 2018 NCI 5R01CA190261-04 The impact of chromosome 17p lesions on leukemogeneis and therapy response LOWE, SCOTT SLOAN-KETTERING INST CAN RESEARCH NY $402,371
Childhood Leukemia 2018 NCI 5R01CA201069-03 Pathway Specific Combinational Therapy in Poor Prognosis B-Lineage Acute Lymphoblastic Leukemia OPFERMAN, JOSEPH ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $410,606
Childhood Leukemia 2018 NCI 5K08CA190815-04 REGULATORY MECHANISMS OF HOX GENE EXPRESSION IN ACUTE MYELOID LEUKEMIA SPENCER, DAVID WASHINGTON UNIVERSITY MO $166,298
Childhood Leukemia 2018 NCI 5P01CA077852-19 5812 Replication Stress Signatures MONNAT, RAYMOND UNIVERSITY OF WASHINGTON WA $361,839
Childhood Leukemia 2018 NCI 5P01CA077852-19 5813 Therapeutic response signatures MAIZELS, NANCY UNIVERSITY OF WASHINGTON WA $307,414
Childhood Leukemia 2018 NCI 5R01CA104509-14 Molecular Mechanism of Leukemogenesis Involving AML1-ETO ZHANG, DONG-ER UNIVERSITY OF CALIFORNIA, SAN DIEGO CA $331,313
Childhood Leukemia 2018 NCI 5U01CA199000-04 Pediatric Preclinical Testing Consortium - Leukemia LOCK, RICHARD UNIVERSITY OF NEW SOUTH WALES AUSTRA $394,802
Childhood Leukemia 2018 NCI 5R01CA209829-03 Targeting CRLF2 and Ikaros Alterations to Reduce Health Disparities in Childhood Leukemia PAYNE, KIMBERLY LOMA LINDA UNIVERSITY CA $360,547
Childhood Leukemia 2018 NCI 5R01CA187318-04 Molecular understanding of cytokine-Ras signals in leukemic bone marrow ROOSE, JEROEN UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $353,777
Childhood Leukemia 2018 NCI 5R01CA036401-35 Pharmacogenomics of Childhood Leukemia ALL EVANS, WILLIAM ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $726,520
Childhood Leukemia 2018 NCI 5K99CA218832-02 The role of histone demethylases in acute myeloid leukemia cell persistence VAN GALEN, PETER MASSACHUSETTS GENERAL HOSPITAL MA $180,360
Childhood Leukemia 2018 NCI 5F31CA206463-03 Clonal Progression of Cancer Cells during Treatment of Acute Lymphoblastic Leukemia CONTRERAS-TRUJILLO, HUMBERTO UNIVERSITY OF SOUTHERN CALIFORNIA CA $43,957
Childhood Leukemia 2018 NCI 5R01CA195732-03 The Role of MMSET in the Pathogenesis and Progression of Lymphoid Malignancy LICHT, JONATHAN UNIVERSITY OF FLORIDA FL $348,844
Childhood Leukemia 2018 NCI 5F31CA206322-03 Mechanism of the methyltransferase Prdm3 in MLL leukemogenesis MCGLYNN, KELLY UNIVERSITY OF ROCHESTER NY $44,524
Childhood Leukemia 2018 NCI 5R01CA211734-02 Oncogenic pathways and therapeutic targets in T cell acute lymphoblastic leukemia LANGENAU, DAVID MASSACHUSETTS GENERAL HOSPITAL MA $391,163
Childhood Leukemia 2018 NCI 5R00CA197869-04 Functional dissection of oncogenic enhancers HERRANZ BENITO, DANIEL RBHS -CANCER INSTITUTE OF NEW JERSEY NJ $249,000
Childhood Leukemia 2018 NIGMS 5P20GM103548-08 5159 Exploring the origins of childhood leukemia: investigating transcriptional networks in hematopoiesis and acute leukemia MILANOVICH, SAMUEL SANFORD RESEARCH/USD SD $291,192
Childhood Leukemia 2018 NCI 5P30CA013696-44 6105 Lymphoid Development and Malignancy Program EMERSON, STEPHEN COLUMBIA UNIVERSITY HEALTH SCIENCES NY $36,802
Childhood Leukemia 2018 NCI 5P30CA013696-44 6127 Recruitment EMERSON, STEPHEN COLUMBIA UNIVERSITY HEALTH SCIENCES NY $99,976
Childhood Leukemia 2018 NCI 5R01CA219150-02 Anticancer peptide therapeutics LU, WUYUAN UNIVERSITY OF MARYLAND BALTIMORE MD $353,419
Childhood Leukemia 2018 NHLBI 5R01HL130937-03 Genetic characterization of osteoblast-induced leukemias KOUSTENI, STAVROULA COLUMBIA UNIVERSITY HEALTH SCIENCES NY $461,485
Childhood Leukemia 2018 NCI 5P30CA006973-55 8084 Hematologic Malignancies and BMT Program - 02 AMBINDER, RICHARD JOHNS HOPKINS UNIVERSITY MD $55,373
Childhood Leukemia 2018 NCI 5R35CA197561-04 Molecular Pathogenesis of Acute Myeloid Leukemia LEY, TIMOTHY WASHINGTON UNIVERSITY MO $915,000
Childhood Leukemia 2018 NCI 5F31CA206338-03 Myc transcriptional regulation in T-ALL FORSYTH, KATHERINE UNIVERSITY OF PENNSYLVANIA PA $44,524
Childhood Leukemia 2018 NCI 5R01CA216981-02 Molecular characterization and targeting of NT5C2 mutations in acute lymphoblastic leukemia FERRANDO, ADOLFO COLUMBIA UNIVERSITY HEALTH SCIENCES NY $382,254
Childhood Leukemia 2018 NIEHS 5P50ES018172-09 5328 Core A - Administrative Core METAYER, CATHERINE UNIVERSITY OF CALIFORNIA BERKELEY CA $195,770
Childhood Leukemia 2018 NIEHS 5P50ES018172-09 5329 Project 1 - In Utero Chemical Exposures, Immune Status, and Childhood Leukemia METAYER, CATHERINE UNIVERSITY OF CALIFORNIA BERKELEY CA $141,332
Childhood Leukemia 2018 NIEHS 5P50ES018172-09 5330 Project 2 - Identifying In Utero Exposures that are Risk Factors for Childhood Leukemia RAPPAPORT, STEPHEN UNIVERSITY OF CALIFORNIA BERKELEY CA $144,457
Childhood Leukemia 2018 NIEHS 5P50ES018172-09 5331 Project 3 - Prenatal Exposures, Constitutive Genetics, DNA Methylation & Childhood Leukemia WIEMELS, JOSEPH UNIVERSITY OF CALIFORNIA BERKELEY CA $93,857
Childhood Leukemia 2018 NIEHS 5P50ES018172-09 5332 Core B - Community Outreach and Translation Core MILLER, MARK UNIVERSITY OF CALIFORNIA BERKELEY CA $72,437
Childhood Leukemia 2018 NIEHS 5P50ES018172-09 5333 Core C - Mouse Model Service Core KOGAN, SCOTT UNIVERSITY OF CALIFORNIA BERKELEY CA $52,147
Childhood Leukemia 2018 NHLBI 5R01HL130995-03 Germline mutations of PTPN11 (SHP-2) in the stem cell microenvironment QU, CHENG-KUI EMORY UNIVERSITY GA $390,000
Childhood Leukemia 2018 NCI 1R01CA214888-01A1 Functional and Translational Epigenomics of Acute Lymphoblastic Leukemia CLEARY, MICHAEL STANFORD UNIVERSITY CA $366,681
Childhood Leukemia 2018 NCI 5R01CA219345-02 Small-molecule MDM2 degraders WANG, SHAOMENG UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $624,777
Childhood Leukemia 2018 NCI 1R01CA220568-01A1 Identifying children with subclinical neurocognitive decline and susceptibility to oxidative damage during the early months of therapy for ALL COLE, PETER RBHS -CANCER INSTITUTE OF NEW JERSEY NJ $695,429
Childhood Leukemia 2018 NCI 1R01CA223194-01A1 RIP1/RIP3-Calpain-Stat3 and NF-kappa B pathways in AML pathogenesis and treatment ZHANG, JIWANG LOYOLA UNIVERSITY CHICAGO IL $339,529
Childhood Leukemia 2018 NCI 2R01CA142714-06A1 Predictors of Myelodysplastic Syndrome in Minnesota POYNTER, JENNY UNIVERSITY OF MINNESOTA MN $600,172
Childhood Leukemia 2018 NCI 2R01CA172896-06 Understanding the niche of minimal residual disease leukemia cells KIM, YONG-MI CHILDREN'S HOSPITAL OF LOS ANGELES CA $402,563
Childhood Leukemia 2018 NCI 5R01CA202025-03 Mapping cancer micro-environments for acute leukemia AIFANTIS, IANNIS NEW YORK UNIVERSITY SCHOOL OF MEDICINE NY $455,870
Childhood Leukemia 2018 NCI 5R01CA212190-02 Longitudinal, multimodal assessment of neuropsychological functioning in children diagnosed with high-risk acute lymphoblastic leukemia (HR-ALL): Using early changes to predict later impairment HARDY, KRISTINA CHILDREN'S RESEARCH INSTITUTE DC $374,232
Childhood Leukemia 2018 NCI 5F30CA217027-02 Investigating the role of miR-155 and the interferon response in FLT3-ITD+ AML WALLACE, JARED UNIVERSITY OF UTAH UT $49,524
Childhood Leukemia 2018 NCI 5R01CA096899-13 Mechanism(s) of TAL1-and NOTCH1-mediated Leukemogenesis KELLIHER, MICHELLE UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $358,031
Childhood Leukemia 2018 NCI 5P30CA125123-12 8015 Pediatric Cancer Program (Project-007) POPLACK, DAVID BAYLOR COLLEGE OF MEDICINE TX $66,213
Childhood Leukemia 2018 NCI 5R00CA181488-05 The Role of EglN1 and HIF in Normal Hematopoiesis and in Leukemia LOSMAN, JULIE DANA-FARBER CANCER INST MA $249,000
Childhood Leukemia 2018 NCI 5F30CA210518-03 Evaluation of Bruton’s Tyrosine Kinase and p110 delta in Mutant Shp2-Induced JMML DENG, LISA INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS IN $49,524
Childhood Leukemia 2018 NCI 5R01CA194094-04 Discovery and Development of a Selective pan-FLT3-ITD Kinase Inhibitor Clinical Candidate for the Treatment of FLT3-ITD-Driven AML LI, HONG-YU UNIV OF ARKANSAS FOR MED SCIS AR $358,560
Childhood Leukemia 2018 NCI 1K07CA218362-01A1 Integrative Molecular Epidemiology of Neurocognitive Outcomes in Acute Lymphoblastic Leukemia BROWN, AUSTIN BAYLOR COLLEGE OF MEDICINE TX $166,043
Childhood Leukemia 2018 NCI 1K22CA218466-01A1 The Role of miR-29b in NK cell Development in Acute Myeloid Leukemia MUNDY-BOSSE, BETHANY OHIO STATE UNIVERSITY OH $186,840
Childhood Leukemia 2018 NHLBI 1K08HL138142-01A1 Investigation of ERBB2 and ERBB3 in hematopoiesis and predisposition to hematologic disease BRAUNSTEIN, EVAN JOHNS HOPKINS UNIVERSITY MD $172,530
Childhood Leukemia 2018 NCI 5R01CA176624-05 Tsc1/mTOR axis in immune homeostasis and tumorigenesis CHI, HONGBO ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $372,463
Childhood Leukemia 2018 NCI 5R01CA187397-05 Exercise and QUality diet After Leukemia TONOREZOS, EMILY SLOAN-KETTERING INST CAN RESEARCH NY $613,996
Childhood Leukemia 2018 NCI 5R01CA207217-03 Exploring oncogenic translation programs in cancer WENDEL, HANS-GUIDO SLOAN-KETTERING INST CAN RESEARCH NY $406,648
Childhood Leukemia 2018 NCI 1R21CA221702-01A1 Directed Purinergic Signaling as Immunotherapy in Leukemia ROBSON, SIMON BETH ISRAEL DEACONESS MEDICAL CENTER MA $228,375
Childhood Leukemia 2018 NCI 5K08CA184552-05 Role of ErbB receptor signaling in regulating normal and leukemic stem cell fate DOAN, PHUONG DUKE UNIVERSITY NC $127,865
Childhood Leukemia 2018 NCI 5R35CA210030-03 Integrating Transforming Approaches to Identify and Target New Vulnerabilities in Cancer STEGMAIER, KIMBERLY DANA-FARBER CANCER INST MA $1,046,441
Childhood Leukemia 2018 NCI 5R01CA166835-07 Targeted Therapy for t(8;21)+ AML NIMER, STEPHEN UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $345,375
Childhood Leukemia 2018 NCI 5R01CA196604-04 Direct coregulation of Notch1 by Zmiz1 in T-cell leukemia CHIANG, MARK UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $354,563
Childhood Leukemia 2018 NHLBI 5R01HL132921-02 Mitotic failure in Fanconi anemia: mechanisms and role in carcinogenesis NALEPA, GRZEGORZ INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS IN $393,750
Childhood Leukemia 2018 NCI 5R01CA187903-04 CHARACTERIZATION OF THE MOLECULAR INTERPLAY BETWEEN HOXA9 AND OGT IN ACUTE LEUKEMIA RUAL, JEAN-FRANCOIS UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $354,563
Childhood Leukemia 2018 NCI 5R01CA175026-05 Using Stat3 Signaling Profiles to Understand Chemotherapy Resistance in AML REDELL, MICHELE BAYLOR COLLEGE OF MEDICINE TX $379,294
Childhood Leukemia 2018 NCI 5R50CA211534-03 Development of novel therapies for megakaryocytic malignancies WEN, QIANG NORTHWESTERN UNIVERSITY AT CHICAGO IL $130,753
Childhood Leukemia 2018 NCI 5K08CA212252-02 Overcoming resistance in BCR-ABL-rearranged acute lymphoblastic leukemia MURAKAMI, MARK DANA-FARBER CANCER INST MA $177,120
Childhood Leukemia 2018 NCI 5R01CA090576-18 STUDIES OF BCR-ABL LEUKEMOGENESIS IN MICE VAN ETTEN, RICHARD UNIVERSITY OF CALIFORNIA-IRVINE CA $293,550
Childhood Leukemia 2018 NIAID 5R21AI129426-02 Connecting Epigenetic Regulator MLL1 to ERK and Survival Signaling in B cells ERNST, PATRICIA UNIVERSITY OF COLORADO DENVER CO $189,333
Childhood Leukemia 2018 NCI 5K08CA194275-02 Characterization of CD99 as a Therapeutic Target in the Myelodysplastic Syndromes and Acute Myeloid Leukemia CHUNG, STEPHEN SLOAN-KETTERING INST CAN RESEARCH NY $177,336
Childhood Leukemia 2018 NCI 5K07CA211847-03 Material Hardship as a Targetable Measure of Poverty in Pediatric Cancer BONA, KIRA DANA-FARBER CANCER INST MA $133,475
Childhood Leukemia 2018 NCI 5R03CA219724-02 Identification of microRNA variants associated with acute lymphoblastic leukemia DEWAN, ANDREW YALE UNIVERSITY CT $83,750
Childhood Leukemia 2018 NCI 5F30CA221109-02 Epigenetic Regulation in High-Risk Leukemia PAYNE, JONATHON PENNSYLVANIA STATE UNIV HERSHEY MED CTR PA $49,524
Childhood Leukemia 2018 NCI 5R01CA178387-05 HDAC8 Mediated Regulation of Acute Myeloid Leukemia Pathogenesis and Maintenance KUO, YA-HUEI BECKMAN RESEARCH INSTITUTE/CITY OF HOPE CA $317,475
Childhood Leukemia 2018 NCI 5R35CA197697-04 Mechanisms of regulation by RNA in acute myeloid leukemia TENEN, DANIEL BETH ISRAEL DEACONESS MEDICAL CENTER MA $1,042,185
Childhood Leukemia 2018 NCI 5R50CA211542-03 Integration of gene expression patterns, fusions, mutations, cytogenetics and other clinical variables for subtyping leukemias and targeting therapies HARVEY, RICHARD UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR NM $154,500
Childhood Leukemia 2018 NHLBI 5UG1HL069290-18 ALT-803 (IL-15/IL-15Rα-Fc) maintenance after allogeneic transplantation for AML BRUNSTEIN, CLAUDIO UNIVERSITY OF MINNESOTA MN $175,560
Childhood Leukemia 2018 NHLBI 5UG1HL069274-18 Blood and Marrow Transplant Clinical Trials Network KURTZBERG, JOANNE DUKE UNIVERSITY NC $177,927
Childhood Leukemia 2018 NHLBI 5UG1HL109137-08 A Phase II Study of Cytokine Induced Memory-like (CIML) Natural Killer (NK) Cell Adoptive Therapy after Haploidentical Donor Hematopoietic Cell Transplantation. WESTERVELT, PETER WASHINGTON UNIVERSITY MO $170,474
Childhood Leukemia 2018 NHLBI 5UG1HL138658-02 Novel Strategies for Assessing and Optimizing Therapy for Minimal Residual Disease after Allogeneic Transplantation for AML and MDS MAZIARZ, RICHARD OREGON HEALTH & SCIENCE UNIVERSITY OR $177,267
Childhood Leukemia 2018 NCI 5P30CA016520-42 8007 Hematologic Malignancies Research Program STADTMAUER, EDWARD UNIVERSITY OF PENNSYLVANIA PA $155,630
Childhood Leukemia 2018 NHLBI 5UG1HL109526-08 Reduction of Relapse Risk Through Incorporation of Novel Biologic Agents Following Reduced Intensity Haploidentical Donor Transplant for Acute Myeloid Leukemia. BASHEY, ASAD NORTHSIDE HOSPITAL ATLANTA GA $149,563
Childhood Leukemia 2018 NCI 5R01CA140729-08 Drug resistant pathways in relapsed acute lymphoblastic leukemia (ALL) CARROLL, WILLIAM NEW YORK UNIVERSITY SCHOOL OF MEDICINE NY $461,060
Childhood Leukemia 2018 NCI 5R01CA204396-03 Aberrant signaling in acute myeloid leukemia KENTSIS, ALEX SLOAN-KETTERING INST CAN RESEARCH NY $459,674
Childhood Leukemia 2018 NHLBI 1F30HL142161-01 Uncovering the Role of the DEAD Box Helicase Ddx41 in Hematopoiesis WEINREB, JOSHUA ALBERT EINSTEIN COLLEGE OF MEDICINE, INC NY $49,524
Childhood Leukemia 2018 NCI 5R01CA196658-03 A rapid spontaneous murine model of CN-AML GRIMES, H. CINCINNATI CHILDRENS HOSP MED CTR OH $567,086
Childhood Leukemia 2018 NCI 1R01CA217954-01A1 Advancing biological and clinical applications of genomic Minimal Residual Disease detection in AML MALEK, SAMI UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $429,758
Childhood Leukemia 2018 NCI 5F31CA216976-02 The Effect Of Cohesin Mutations In Hematologic Malignancies MCNULTY, MAUREEN NORTHWESTERN UNIVERSITY AT CHICAGO IL $38,609
Childhood Leukemia 2018 NCI 5F31CA221002-02 Engineering chimeric antigen receptors with VLR-mediated cancer recognition in CD5 edited gamma delta T cells FLEISCHER, LAUREN EMORY UNIVERSITY GA $44,524
Childhood Leukemia 2018 NCI 1F30CA228228-01 Exploiting the Context-Dependence of Notch to Develop Safer T-ALL therapy GORMLEY, ANNA UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $36,023
Childhood Leukemia 2018 NHLBI 5F31HL132420-03 Aberrant Ubiquitin-Editing in the Pathogenesis of Myeloid Malignancies SMITH, MOLLY CINCINNATI CHILDRENS HOSP MED CTR OH $37,505
Childhood Leukemia 2018 NCI 5R00CA188595-04 Determining the role of DNMT-interacting RNAs in myeloid disorders DI RUSCIO, ANNALISA BETH ISRAEL DEACONESS MEDICAL CENTER MA $249,000
Childhood Leukemia 2018 NIEHS 5K01ES026842-04 Connecting Single Cell Heterogeneity to Clinical Descriptors of Clonal Evolution in Acute Myeloid Leukemia PAGUIRIGAN, AMY FRED HUTCHINSON CANCER RESEARCH CENTER WA $119,855
Childhood Leukemia 2018 NCI 5R01CA138744-09 Tyrosine kinase inhibitors for the treatment of childhood AML BAKER, SHARYN OHIO STATE UNIVERSITY OH $343,388
Childhood Leukemia 2018 NCI 1F31CA228391-01 Nanoparticle mediated microenvironmental targeting of CCL3 signaling for the treatment of acute myelogenous leukemia ACKUN-FARMMER, MARIAN UNIVERSITY OF ROCHESTER NY $42,418
Childhood Leukemia 2018 NCI 5R01CA180519-05 Novel anthraquinones induce apoptosis by disruption MDM2/MDM4 interactions WANG, BINGHE GEORGIA STATE UNIVERSITY GA $442,311
Childhood Leukemia 2018 NCI 5R01CA205239-02 TRANSLATING NK CELL BIOLOGY INTO CLINICAL CANCER IMMUNOTHERAPY FEHNIGER, TODD WASHINGTON UNIVERSITY MO $614,214
Childhood Leukemia 2018 NCI 5K22CA190674-04 Regulation of Ceramide-Based Therapeutics in Acute Myeloid Leukemia BARTH, BRIAN UNIVERSITY OF NEW HAMPSHIRE NH $161,692
Childhood Leukemia 2018 NCI 5K08CA188529-05 Genomic profiling and development of murine models of transformation of MPNs RAMPAL, RAAJIT SLOAN-KETTERING INST CAN RESEARCH NY $178,200
Childhood Leukemia 2018 NCI 5K22CA218467-02 Probing the role of the IRE1alpha-XBP1 pathway in normal and malignant hematopoiesis ADORO, STANLEY CASE WESTERN RESERVE UNIVERSITY OH $192,575
Childhood Leukemia 2018 NCI 5K08CA212299-03 Molecular Interactions of APOBEC3 Enzymes with the Cancer Genome GREEN, ABBY CHILDREN'S HOSP OF PHILADELPHIA PA $148,742
Childhood Leukemia 2018 NCI 5U54CA196519-04 7041 Project 3: Efficacy of MEK Inhibition in Juvenile Myelomonocytic Leukemia SHANNON, KEVIN UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $425,561
Childhood Leukemia 2018 NCI 1R01CA224436-01A1 MLL Family Histone Methyltransferases in Myeloid Leukemia ERNST, PATRICIA UNIVERSITY OF COLORADO DENVER CO $424,527
Childhood Leukemia 2018 NCI 5K01CA188151-04 Targeted Alpha Radioimmunotherapy with Haploidentical Bone Marrow Transplantation for AML OROZCO, JOHNNIE FRED HUTCHINSON CANCER RESEARCH CENTER WA $169,020
Childhood Leukemia 2018 NCI 5P01CA078902-20 5394 Project 2: Stem Cell Allografts for Acute Leukemia and Myelodysplasia SANDMAIER, BRENDA FRED HUTCHINSON CANCER RESEARCH CENTER WA $114,301
Childhood Leukemia 2018 NCI 5K08CA201483-03 Investigating L-2-hydroxyglutarate in normal hematopoiesis and leukemogenesis INTLEKOFER, ANDREW SLOAN-KETTERING INST CAN RESEARCH NY $177,336
Childhood Leukemia 2018 NCI 5R35CA210064-03 Mechanisms and Vulnerabilities of Aberrant Transcriptional Enhancers in Cancer LOOK, A. DANA-FARBER CANCER INST MA $1,046,441
Childhood Leukemia 2018 NCI 5R01CA213129-02 Sequestration and deactivation of anthracycline by adipocytes in the leukemia microenvironment MITTELMAN, STEVEN UNIVERSITY OF CALIFORNIA LOS ANGELES CA $363,465
Childhood Leukemia 2018 NCI 5R01CA181050-05 KIR-FAVORABLE HAPLOIDENTICAL TRANSPLANTATION IN CHILDREN PULSIPHER, MICHAEL CHILDREN'S HOSPITAL OF LOS ANGELES CA $291,828
Childhood Leukemia 2018 NCI 5P01CA214278-02 8888 Project 1: Overcoming resistance of B cell leukemia to CD19 CAR T Cells. PORTER, DAVID UNIVERSITY OF PENNSYLVANIA PA $402,534
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