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RCDC

Project Listing by Category


Back to Estimates of Funding for Various Research, Condition, and Disease Categories (RCDC) Click the column headings to sort project listings.
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CategoryFYFunding ICProject NumberSub Project #Project TitlePI NameOrg NameState / CountryAmount
Transmissible Spongiform Encephalopathy (TSE) 2017 NINDS 5F32NS095587-02 Characterizing the Cellular Biology of Prion Strains and the Factors that Drive Prion Pathogenesis LOPEZ, TIMOTHY UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $63,479
Transmissible Spongiform Encephalopathy (TSE) 2017 NIA 5R37AG031220-10 Towards Therapeutics for Neurodegenerative Diseases PRUSINER, STANLEY UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $645,645
Transmissible Spongiform Encephalopathy (TSE) 2017 NINDS 5R21NS096626-02 Accessing transmissibility and diagnostic marker of skin prions. ZOU, WEN-QUAN CASE WESTERN RESERVE UNIVERSITY OH $198,125
Transmissible Spongiform Encephalopathy (TSE) 2017 NIA 5R01NS065244-07 Mechanisms of Prion Protein Toxicity HARRIS, DAVID BOSTON UNIVERSITY MEDICAL CAMPUS MA $111,826
Transmissible Spongiform Encephalopathy (TSE) 2017 NINDS 5R01NS065244-07 Mechanisms of Prion Protein Toxicity HARRIS, DAVID BOSTON UNIVERSITY MEDICAL CAMPUS MA $527,181
Transmissible Spongiform Encephalopathy (TSE) 2017 NINDS 5R21NS096662-02 Fyn activation in prion disease TELLING, GLENN COLORADO STATE UNIVERSITY CO $189,688
Transmissible Spongiform Encephalopathy (TSE) 2017 NINDS 5R21NS093488-02 Mode of action of a neuroprotective compound LASMEZAS, CORINNE SCRIPPS FLORIDA FL $192,000
Transmissible Spongiform Encephalopathy (TSE) 2017 NINDS 5R01NS061902-08 PMCA Detection of CWD Infection in Cervid and Non-Cervid Species HOOVER, EDWARD COLORADO STATE UNIVERSITY CO $409,868
Transmissible Spongiform Encephalopathy (TSE) 2017 NIGMS 2R01GM099836-05 Defining the mechanistic basis of a prion disaggregase SHORTER, JAMES UNIVERSITY OF PENNSYLVANIA PA $339,308
Transmissible Spongiform Encephalopathy (TSE) 2017 NIA 5P50AG023501-14 5930 Core B: Clinical Core KRAMER, JOEL UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $402,049
Transmissible Spongiform Encephalopathy (TSE) 2017 NIA 5R01AG049668-03 PrPC- and NOX-dependent signaling in dementia BAMBURG, JAMES COLORADO STATE UNIVERSITY CO $274,352
Transmissible Spongiform Encephalopathy (TSE) 2017 NIA 5P01AG002132-36 8435 Core B: Science GILES, KURT UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $245,600
Transmissible Spongiform Encephalopathy (TSE) 2017 NIA 5P01AG002132-36 8437 Core D: Animals PRUSINER, STANLEY UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $316,296
Transmissible Spongiform Encephalopathy (TSE) 2017 NIA 5P01AG002132-36 8438 Project 1: Abeta, tau and PrP prions causing neurodegenerative diseases PRUSINER, STANLEY UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $382,827
Transmissible Spongiform Encephalopathy (TSE) 2017 NIA 5P01AG002132-36 8439 Project 2: Structural studies of prions STUBBS, GERALD UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $278,627
Transmissible Spongiform Encephalopathy (TSE) 2017 NIA 5P01AG002132-36 8440 Project 3: Assembly and structures of Abeta peptides. DEGRADO, WILLIAM UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $327,752
Transmissible Spongiform Encephalopathy (TSE) 2017 NIA 5P01AG002132-36 8441 Project 4: Structural modeling of Abeta, tau and PrP prion self-assembly SALI, ANDREJ UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $242,760
Transmissible Spongiform Encephalopathy (TSE) 2017 NINDS 5R01NS046478-14 Origin and Mechanism of Promiscuous Prion Strains SUPATTAPONE, SURACHAI DARTMOUTH COLLEGE NH $422,549
Transmissible Spongiform Encephalopathy (TSE) 2017 NIGMS 5R01GM110448-04 Structural biology of yeast prions. GUO, ZHEFENG UNIVERSITY OF CALIFORNIA LOS ANGELES CA $292,600
Transmissible Spongiform Encephalopathy (TSE) 2017 NIA 5P30AG008051-28 5041 Core D. Neuropathology Core (with IBR Subcontract) WISNIEWSKI, THOMAS NEW YORK UNIVERSITY SCHOOL OF MEDICINE NY $192,336
Transmissible Spongiform Encephalopathy (TSE) 2017 NINDS 5R21NS095763-02 Long-Term Safety, Efficacy, and Mechanism of PERK Inhibition Therapy for Prion Disease SUPATTAPONE, SURACHAI DARTMOUTH COLLEGE NH $202,500
Transmissible Spongiform Encephalopathy (TSE) 2017 NINDS 5R01NS083687-04 Structural correlates of prion strain, phenotype and infectivity in human prion d GAMBETTI, PIERLUIGI CASE WESTERN RESERVE UNIVERSITY OH $585,285
Transmissible Spongiform Encephalopathy (TSE) 2017 NINDS 5R21NS096627-03 Intrinsic and extrinsic factors regulating prion protein neurotoxicity FERNANDEZ-FUNEZ, PEDRO UNIVERSITY OF MINNESOTA MN $191,250
Transmissible Spongiform Encephalopathy (TSE) 2017 NINDS 5R01NS092145-07 The iron modulatory function of prion protein and prion disorders SINGH, NEENA CASE WESTERN RESERVE UNIVERSITY OH $498,026
Transmissible Spongiform Encephalopathy (TSE) 2017 NIAID 5P01AI077774-07 5320 Administrative Core SOTO, CLAUDIO UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON TX $164,865
Transmissible Spongiform Encephalopathy (TSE) 2017 NIAID 5P01AI077774-07 5321 Science Core B TELLING, GLENN COLORADO STATE UNIVERSITY CO $310,930
Transmissible Spongiform Encephalopathy (TSE) 2017 NIAID 5P01AI077774-07 5322 Mechanisms of Prion Transmission, Evolution and Adaptation TELLING, GLENN COLORADO STATE UNIVERSITY CO $545,975
Transmissible Spongiform Encephalopathy (TSE) 2017 NIAID 5P01AI077774-07 5323 Zoonotic potential of CWD and influence of environmental contamination on prion propagation SOTO, CLAUDIO UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON TX $557,985
Transmissible Spongiform Encephalopathy (TSE) 2017 NIAID 5P01AI077774-07 5324 CWD Prion Shedding and Environmental Contamination: Role in Transmission and Zoonotic Potential HOOVER, EDWARD COLORADO STATE UNIVERSITY CO $635,641
Transmissible Spongiform Encephalopathy (TSE) 2017 NIAID 5R01AI112956-04 Detection and Characterization of Blood-borne Prions MATHIASON, CANDACE COLORADO STATE UNIVERSITY CO $454,741
Transmissible Spongiform Encephalopathy (TSE) 2017 NIGMS 5R01GM065790-15 Molecular aspects of copper and zinc binding to the prion protein MILLHAUSER, GLENN UNIVERSITY OF CALIFORNIA SANTA CRUZ CA $313,632
Transmissible Spongiform Encephalopathy (TSE) 2017 OD 5F30OD021442-03 Characterizing the Role of Protein Interactions in Prion Disease Species Barriers DAVENPORT, KRISTEN COLORADO STATE UNIVERSITY CO $48,618
Transmissible Spongiform Encephalopathy (TSE) 2017 NIA 5R01AG031189-10 Predicting progression of human prion disease GESCHWIND, MICHAEL UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $586,201
Transmissible Spongiform Encephalopathy (TSE) 2017 NINDS 5R01NS060729-10 Synthetically generated mammalian prions MA, JIYAN VAN ANDEL RESEARCH INSTITUTE MI $588,378
Transmissible Spongiform Encephalopathy (TSE) 2017 NIGMS 5R01GM115941-02 Amyloid aggregation and prion formation in bacteria HOCHSCHILD, ANN HARVARD MEDICAL SCHOOL MA $477,885
Transmissible Spongiform Encephalopathy (TSE) 2017 NIA 5R01AG048912-04 GDE and Neurodegenerative Diseases SOCKANATHAN, SHANTHINI JOHNS HOPKINS UNIVERSITY MD $324,000
Transmissible Spongiform Encephalopathy (TSE) 2017 NINDS 5R01NS069566-07 Mechanisms of Prion Aggregation and Species Barriers SIGURDSON, CHRISTINA UNIVERSITY OF CALIFORNIA SAN DIEGO CA $339,063
Transmissible Spongiform Encephalopathy (TSE) 2017 NINDS 1R21NS101659-01 Identification of Anti-Prion Drug Targets HARRIS, DAVID BOSTON UNIVERSITY MEDICAL CAMPUS MA $246,750
Transmissible Spongiform Encephalopathy (TSE) 2017 NIA 1R01NS097490-01A1 Solid-state NMR Structural Characterizations of Polymorphic Transthyretin Amyloids LIM, KWANG HUN EAST CAROLINA UNIVERSITY NC $131,350
Transmissible Spongiform Encephalopathy (TSE) 2017 NIAID 5F31AI122592-02 Developing in vitro assays to identify small molecules that inhibit human prions MINIKEL, ERIC HARVARD MEDICAL SCHOOL MA $36,765
Transmissible Spongiform Encephalopathy (TSE) 2017 NIGMS 5R01GM105991-05 The determinants of aggregation and toxicity of prion-like domains ROSS, ERIC COLORADO STATE UNIVERSITY CO $290,525
Transmissible Spongiform Encephalopathy (TSE) 2017 NIGMS 5R35GM119790-02 Using naturally-occurring fungal prions as models of neurodegenerative protein misfolding SHEWMAKER, FRANK HENRY M. JACKSON FDN FOR THE ADV MIL/MED MD $210,486
Transmissible Spongiform Encephalopathy (TSE) 2017 NINDS 1R21NS099928-01A1 Combination Chemotherapy for Treatment of Prion Disease SUPATTAPONE, SURACHAI DARTMOUTH COLLEGE NH $243,000
Transmissible Spongiform Encephalopathy (TSE) 2017 NIGMS 5R01GM109455-05 Robust rare event simulation for protein folding and disease-related aggregation WEARE, JONATHAN UNIVERSITY OF CHICAGO IL $333,596
Transmissible Spongiform Encephalopathy (TSE) 2017 NINDS 5R01NS088604-03 Cervid to human prion transmission KONG, QINGZHONG CASE WESTERN RESERVE UNIVERSITY OH $341,602
Transmissible Spongiform Encephalopathy (TSE) 2017 NIGMS 5R01GM056350-19 Exploring the toxicity of aggregates associated with protein-misfolding diseases LIEBMAN, SUSAN UNIVERSITY OF NEVADA RENO NV $371,610
Transmissible Spongiform Encephalopathy (TSE) 2017 NIAID 1R01AI128925-01A1 Role of prion protein sialylation in prion diseases BASKAKOV, ILIA UNIVERSITY OF MARYLAND BALTIMORE MD $719,789
Transmissible Spongiform Encephalopathy (TSE) 2017 NIAID 5P01AI106705-04 7014 Molecular and Structural Basis of Prion Protein Conversion to the infectious Form SUREWICZ, WITOLD CASE WESTERN RESERVE UNIVERSITY OH $391,581
Transmissible Spongiform Encephalopathy (TSE) 2017 NIAID 5P01AI106705-04 7015 Molecular Basis of Factors Controlling Prion Strain Diversity and Species Barrier SOTO, CLAUDIO UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON TX $446,600
Transmissible Spongiform Encephalopathy (TSE) 2017 NIAID 5P01AI106705-04 7016 Mechanisms of Human Prion Disease Diversity GAMBETTI, PIERLUIGI CASE WESTERN RESERVE UNIVERSITY OH $186,715
Transmissible Spongiform Encephalopathy (TSE) 2017 NIAID 5P01AI106705-04 7017 Administrative Core SUREWICZ, WITOLD CASE WESTERN RESERVE UNIVERSITY OH $97,883
Transmissible Spongiform Encephalopathy (TSE) 2017 NIAID 5P01AI106705-04 7018 Animal Core CONLON, RONALD CASE WESTERN RESERVE UNIVERSITY OH $296,018
Transmissible Spongiform Encephalopathy (TSE) 2017 NIAID 5P01AI106705-04 7019 Neuropathology Core - P Gambetti GAMBETTI, PIERLUIGI CASE WESTERN RESERVE UNIVERSITY OH $121,333
Transmissible Spongiform Encephalopathy (TSE) 2017 NINDS 5SB1NS079060-05 Development of a Biochemical Diagnosis for Creutzfeldt-Jakob disease LEBOVITZ, RUSSELL AMPRION, INC. CA $1,213,869
Transmissible Spongiform Encephalopathy (TSE) 2017 NIAID 1R01AI132695-01 Shedding, retention and spreading of chronic wasting disease prions in the environment MORALES, RODRIGO UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON TX $558,920
Transmissible Spongiform Encephalopathy (TSE) 2017 NIGMS 2R15GM110606-02 J-Protein Regulation of Yeast Prion Propagation HINES, JUSTIN LAFAYETTE COLLEGE PA $394,870
Transmissible Spongiform Encephalopathy (TSE) 2017 NIGMS 1F32GM125162-01 Using self-templating proteins to spatiotemporally organize biochemistry JAKOBSON, CHRISTOPHER STANFORD UNIVERSITY CA $56,694
Transmissible Spongiform Encephalopathy (TSE) 2017 NINDS 1F31NS103588-01 Targeting vesicular transport pathways in prion disease LAWRENCE, JESSICA UNIVERSITY OF CALIFORNIA SAN DIEGO CA $36,212
Transmissible Spongiform Encephalopathy (TSE) 2017 NINDS 2R01NS076896-06 Mechanisms of Prion Spread SIGURDSON, CHRISTINA UNIVERSITY OF CALIFORNIA SAN DIEGO CA $339,063
Transmissible Spongiform Encephalopathy (TSE) 2017 NIA 3P50AG023501-14S1 New Approaches to Dementia Heterogeneity MILLER, BRUCE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $65,941
Transmissible Spongiform Encephalopathy (TSE) 2017 NIGMS 1R01GM126548-01 Mathematical Strategies to Uncover the Molecular Basis of Prion Transitions SINDI, SUZANNE UNIVERSITY OF CALIFORNIA, MERCED CA $213,561
Transmissible Spongiform Encephalopathy (TSE) 2017 NINDS 1F31NS101807-01A1 Defining the molecular basis of substrate selection by diverse Hsp104 homologues MARCH, ZACHARY UNIVERSITY OF PENNSYLVANIA PA $44,044
Transmissible Spongiform Encephalopathy (TSE) 2017 NIA 3R01AG031189-10S1 Predicting progression of human prion disease GESCHWIND, MICHAEL UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $136,520
Transmissible Spongiform Encephalopathy (TSE) 2017 NINDS 1R56NS103195-01 Early development of small molecule neuroprotectants LASMEZAS, CORINNE SCRIPPS FLORIDA FL $666,166
Transmissible Spongiform Encephalopathy (TSE) 2017 NINDS 1R56NS102301-01 Dissecting the Mechanism of Prion Formation with a Permissive Host SUPATTAPONE, SURACHAI DARTMOUTH COLLEGE NH $521,059
Transmissible Spongiform Encephalopathy (TSE) 2017 NINDS 1R56NS094576-01A1 Structural Mechanism of Mammalian Prion Infectivity SUPATTAPONE, SURACHAI DARTMOUTH COLLEGE NH $567,000
Transmissible Spongiform Encephalopathy (TSE) 2017 NIGMS 7R35GM118042-03 Cellular Mechanisms and Consequences of Protein Misfolding and Resolution SERIO, TRICIA UNIVERSITY OF MASSACHUSETTS AMHERST MA $324,974
Transmissible Spongiform Encephalopathy (TSE) 2017 NIDDK 276201300171U-5-0-1 CREUTZFELDT-JAKOB DISEASE SURVEILLANCE IN RECIPIENTS OF HUMAN GROWTH HORMONE DURAKO, STEVE WESTAT, INC. MD $260,634
Transmissible Spongiform Encephalopathy (TSE) 2017 NIDDK 1ZIADK024950-11 Biological Roles and Structures of Yeast Prions WICKNER, REED NIH $1,550,698
Transmissible Spongiform Encephalopathy (TSE) 2017 NIGMS 3R01GM115941-02S1 Amyloid aggregation and prion formation in bacteria HOCHSCHILD, ANN HARVARD MEDICAL SCHOOL MA $15,939
Transmissible Spongiform Encephalopathy (TSE) 2017 NIAID 1ZIAAI000937-14 Biology of Prion Protein and the TSE Diseases CHESEBRO, BRUCE NIH $1,045,516
Transmissible Spongiform Encephalopathy (TSE) 2017 NIAID 1ZIAAI001087-08 Prion Disease Therapeutics CAUGHEY, BYRON NIH $326,918
Transmissible Spongiform Encephalopathy (TSE) 2017 NIAID 1ZIAAI000580-28 Structures and Activities of Prions and Prion Proteins CAUGHEY, BYRON NIH $490,377
Transmissible Spongiform Encephalopathy (TSE) 2017 NIAID 1ZIAAI000752-22 Molecular Genetics Of Scrapie Pathogenesis PRIOLA, SUZETTE NIH $931,637
Transmissible Spongiform Encephalopathy (TSE) 2017 NIAMS 1ZIAAR041157-11 Structural Biology of Amyloid and Amyloid-like Proteins STEVEN, ALASDAIR NIH $395,060
Transmissible Spongiform Encephalopathy (TSE) 2017 NIDDK 1ZIADK024946-20 Yeast prions and Hsp70 chaperones MASISON, DANIEL NIH $619,146
Transmissible Spongiform Encephalopathy (TSE) 2017 NIDDK 1ZIADK024954-08 Chaperone-amyloid interactions MASISON, DANIEL NIH $412,764
Transmissible Spongiform Encephalopathy (TSE) 2017 NIDDK 1ZIADK075031-09 Structural Studies of Prion Fibrils and Other Protein Fibrils TYCKO, ROBERT NIH $388,120
Transmissible Spongiform Encephalopathy (TSE) 2017 NIAID 1ZIAAI000983-12 Study of CWD Deer and Elk Prion Disease in Nonhuman Primates CHESEBRO, BRUCE NIH $384,341
Transmissible Spongiform Encephalopathy (TSE) 2017 NIAID 1ZIAAI001086-09 Detection of Prions CAUGHEY, BYRON NIH $817,295
Transmissible Spongiform Encephalopathy (TSE) 2017 NIAID 1ZIAAI001105-09 Molecular Mechanisms of Prion Protein Amyloid Formation PRIOLA, SUZETTE NIH $310,546
Transmissible Spongiform Encephalopathy (TSE) 2017 NIAID 1ZIAAI001219-01 Prion protein function in redox homeostasis and associated failure in prion disease HAIGH, CATHRYN NIH $425,841
Transmissible Spongiform Encephalopathy (TSE) 2017 NHLBI 1ZIAHL000516-31 Role of molecular chaperones in protein folding diseases GREENE, LOIS NIH $1,047,852


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