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RCDC

Project Listing by Category


Back to Estimates of Funding for Various Research, Condition, and Disease Categories (RCDC) Click the column headings to sort project listings.
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CategoryFYFunding ICProject NumberSub Project #Project TitlePI NameOrg NameState / CountryAmount
ALS 2017 NINDS 1R35NS097275-01 Molecular Genetic Insight into Neurodegenerative Disease from Drosophila BONINI, NANCY UNIVERSITY OF PENNSYLVANIA PA $674,853
ALS 2017 NINDS 1R35NS097261-01 Genetic Discovery and Pathobiology of Frontotemporal Lobar Degeneration and Related TDP-43 Proteinopathies RADEMAKERS, ROSA MAYO CLINIC JACKSONVILLE FL $888,569
ALS 2017 NINDS 1R35NS097263-01 Innovating Yeast and Human Genetics Approaches to Define Mechanisms of Neurodegenerative Disease GITLER, AARON STANFORD UNIVERSITY CA $939,520
ALS 2017 NIEHS 5R01ES022310-05 Association of ALS to gene-environment mediated changes in HDL proteins SIDDIQUE, TEEPU NORTHWESTERN UNIVERSITY AT CHICAGO IL $590,048
ALS 2017 NIDCD 5R01DC013547-04 SPEECH MOVEMENT CLASSIFICATION FOR ASSESSING AND TREATING ALS GREEN, JORDAN MGH INSTITUTE OF HEALTH PROFESSIONS MA $581,327
ALS 2017 NIA 5R01AG031867-09 IBMPFD MUTATIONS IMPAIR PROTEIN DEGRADATION WEIHL, CONRAD WASHINGTON UNIVERSITY MO $425,848
ALS 2017 NINDS 5R01NS073829-06 Study on Neurodegeneration using TDP-43 Transgenic Rats ZHOU, HONGXIA THOMAS JEFFERSON UNIVERSITY PA $30,048
ALS 2017 NINDS 5R01NS062055-08 Mitochondria quality control in SOD1-ALS MANFREDI, GIOVANNI WEILL MEDICAL COLL OF CORNELL UNIV NY $370,781
ALS 2017 NINDS 5R01NS057553-11 Animal Models for Studying Human Frontotemporal Dementia GAO, FEN-BIAO UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $366,406
ALS 2017 NINDS 5R01NS091836-03 Mechanisms Underlying Excitability Regulation of Motoneuron Types in ALS ELBASIOUNY, SHERIF WRIGHT STATE UNIVERSITY OH $323,750
ALS 2017 NIEHS 5R01ES024064-03 Environmental Metals, Excitotoxicity and ALS ATCHISON, WILLIAM MICHIGAN STATE UNIVERSITY MI $440,553
ALS 2017 NINDS 5R00NS082376-05 Analysis of the RNA-binding Protein FUS and Its Role in Neurodegenerative Disease SCHWARTZ, JACOB UNIVERSITY OF ARIZONA AZ $258,749
ALS 2017 NIA 5R01NS095969-02 TDP-43 Proteinopathy in ALS-FTD: Mechanism, Target Validation and Biomarker WONG, PHILIP JOHNS HOPKINS UNIVERSITY MD $50,625
ALS 2017 NINDS 5R01NS095969-02 TDP-43 Proteinopathy in ALS-FTD: Mechanism, Target Validation and Biomarker WONG, PHILIP JOHNS HOPKINS UNIVERSITY MD $354,375
ALS 2017 NINDS 5F31NS095571-02 Exploring synaptic abnormalities that underlie hyperactivity in a stem-cell derived model of amyotrophic lateral sclerosis SMERDON, JOHN COLUMBIA UNIVERSITY HEALTH SCIENCES NY $44,044
ALS 2017 NIA 5R01NS096785-07 Integrating Quality Control: Studies of UBQLN2 in Age-Related Neurodegeneration PAULSON, HENRY UNIVERSITY OF MICHIGAN MI $37,432
ALS 2017 NINDS 5R01NS096785-07 Integrating Quality Control: Studies of UBQLN2 in Age-Related Neurodegeneration PAULSON, HENRY UNIVERSITY OF MICHIGAN MI $573,645
ALS 2017 NHLBI 5R00HL119606-04 Enhanced respiratory plasticity in models of respiratory motor neuron death NICHOLS, NICOLE UNIVERSITY OF MISSOURI-COLUMBIA MO $238,260
ALS 2017 NINDS 5F32NS093938-02 Genetic and Functional Characterization of Astrocyte Subtypes in the Spinal Cord GLENN, THOMAS SALK INSTITUTE FOR BIOLOGICAL STUDIES CA $57,066
ALS 2017 NIA 5K01AG049152-03 RNA signatures of frontotemporal dementia and ALS due to C9ORF72 expansion YOKOYAMA, JENNIFER UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $129,600
ALS 2017 NIA 1R01NS099320-01 Oligodendroglial Dysfunction in C9orf72 ALS and FTD ROTHSTEIN, JEFFREY JOHNS HOPKINS UNIVERSITY MD $596,524
ALS 2017 NIA 1R01NS099371-01 CircRNAs and CNS Gene Transfer ASOKAN, ARAVIND UNIV OF NORTH CAROLINA CHAPEL HILL NC $398,672
ALS 2017 NINDS 1P01NS099114-01 7850 Administrative Core DISNEY, MATTHEW SCRIPPS FLORIDA FL $296,280
ALS 2017 NINDS 1P01NS099114-01 7851 Lead Optimization to Support Cellular and Animal Studies ROUSH, WILLIAM SCRIPPS FLORIDA FL $296,280
ALS 2017 NINDS 1P01NS099114-01 7852 Development of small molecule chemical probes to study r(G4C2)exp pathomechanisms DISNEY, MATTHEW SCRIPPS FLORIDA FL $296,280
ALS 2017 NINDS 1P01NS099114-01 7853 Validation of r(G4C2)exp-binding small molecules in vivo and c9FTD/ALS biomarker development PETRUCELLI, LEONARD MAYO CLINIC JACKSONVILLE FL $296,280
ALS 2017 NINDS 1P01NS099114-01 7854 Mitigation of nuclear pore dysfunction in c9FTD/ALS pathogenesis ROTHSTEIN, JEFFREY JOHNS HOPKINS UNIVERSITY MD $296,280
ALS 2017 NINDS 5F32NS090831-03 The contribution of cytoskeleton disruptions in ALS disease pathology DANIELSON, ERIC UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $59,970
ALS 2017 NIA 5R01NS095793-02 Epigenetic Editing of Mutant C9orf72 LEE, EDWARD UNIVERSITY OF PENNSYLVANIA PA $50,000
ALS 2017 NINDS 5R01NS095793-02 Epigenetic Editing of Mutant C9orf72 LEE, EDWARD UNIVERSITY OF PENNSYLVANIA PA $350,000
ALS 2017 NINDS 5R01NS092651-02 Smad Signaling in Skeletal Muscle as a Biomarker of Disease Progression in ALS KING, PETER UNIVERSITY OF ALABAMA AT BIRMINGHAM AL $321,563
ALS 2017 NINDS 5R01NS090962-03 Re-Establishing Vascular Integrity in ALS via Endothelial Cell Transplant GARBUZOVA-DAVIS, SVITLANA UNIVERSITY OF SOUTH FLORIDA FL $327,031
ALS 2017 NIA 1R21NS099631-01 C9ORF72 levels: implications for diagnosis, prognosis, and treatment of ALS and related disorders VAN BLITTERSWIJK, MARKA MAYO CLINIC JACKSONVILLE FL $234,750
ALS 2017 NIA 1R21NS099804-01 New molecular targets against neurotoxic TDP-43 and PR-repeats in Drosophila FERNANDEZ-FUNEZ, PEDRO UNIVERSITY OF MINNESOTA MN $229,750
ALS 2017 NINDS 5R21NS093118-02 TTR and C9ORF72 in ALS and related disorders VAN BLITTERSWIJK, MARKA MAYO CLINIC JACKSONVILLE FL $200,361
ALS 2017 NINDS 5R01NS081303-05 Cellular and Molecular Mechanisms of FUS-related Amyotrophic Lateral Sclerosis PANDEY, UDAI UNIVERSITY OF PITTSBURGH AT PITTSBURGH PA $329,217
ALS 2017 NINDS 5K08NS082364-04 Defining an Electrophysiological Phenotype of ALS Patient-Derived Motor Neurons WAINGER, BRIAN MASSACHUSETTS GENERAL HOSPITAL MA $200,016
ALS 2017 NINDS 5R01NS091540-03 Muscle stem cells: New ALS growth factor therapy and disease model SUZUKI, MASATOSHI UNIVERSITY OF WISCONSIN-MADISON WI $334,688
ALS 2017 NINDS 1R21NS099910-01 Big data screening for associations between medication use and ALS WEISSKOPF, MARC HARVARD SCHOOL OF PUBLIC HEALTH MA $232,901
ALS 2017 NINDS 5R01NS094678-02 Investigating a2-chimaerin-dependent motor neuron protection in ALS BEG, ASIM UNIVERSITY OF MICHIGAN MI $331,122
ALS 2017 NINDS 5K08NS082365-04 The Role of Sirtuin 1 Deacetylase in Amyotrophic Lateral Sclerosis HERSKOVITS, ADRIANNA BRIGHAM AND WOMEN'S HOSPITAL MA $197,510
ALS 2017 NINDS 5R37NS060698-09 Mechanistic analysis of axonal transport defects in neurodegenerative disease HOLZBAUR, ERIKA UNIVERSITY OF PENNSYLVANIA PA $385,720
ALS 2017 NINDS 5R01NS096746-02 AMPK, metabolism and ALS KALB, ROBERT CHILDREN'S HOSP OF PHILADELPHIA PA $470,944
ALS 2017 NINDS 5R00NS087104-04 Novel mechanisms of actin dynamics underlying cell motility, axon growth, and ALS VITRIOL, ERIC UNIVERSITY OF FLORIDA FL $241,438
ALS 2017 NINDS 5R01NS040433-15 Immune Regulation of Neuronal Injury and Repair JONES, KATHRYN INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS IN $461,709
ALS 2017 NINDS 5R21NS096319-02 Modifiers of C9orf72 associated dipeptide protein toxicity in a C. elegans model LAMITINA, SAMUEL UNIVERSITY OF PITTSBURGH AT PITTSBURGH PA $186,012
ALS 2017 NIA 1R21NS098379-01A1 Nuclear export inhibition as a novel therapeutic target for C9ORF72 ALS/FTD DONNELLY, CHRISTOPHER UNIVERSITY OF PITTSBURGH AT PITTSBURGH PA $233,376
ALS 2017 NIDCD 5R01DC014034-03 Advanced neural decoders for the restoration of communication HENDERSON, JAIMIE STANFORD UNIVERSITY CA $760,507
ALS 2017 NINDS 5R01NS072428-05 Role of MMP-9 in selective motor neuron degeneration in ALS PRZEDBORSKI, SERGE COLUMBIA UNIVERSITY HEALTH SCIENCES NY $329,348
ALS 2017 NINDS 1F30NS100217-01 Mechanisms Underlying the Pathogenic Role of an α-Adducin/α2-Na/K ATPase Complex in Amyotrophic Lateral Sclerosis SMITH, SARAH WASHINGTON UNIVERSITY MO $30,651
ALS 2017 NIA 5P50AG005131-34 5888 Project 2: Disease Mechanisms in Frontotemporal Dementia Linked to C9orf72 Expans LAGIER-TOURENNE, CLOTILDE UNIVERSITY OF CALIFORNIA SAN DIEGO CA $202,450
ALS 2017 NINDS 5R01NS093872-03 Metabolic profiling of sporadic ALS patients: from fibroblasts to neurons and back MANFREDI, GIOVANNI WEILL MEDICAL COLL OF CORNELL UNIV NY $530,987
ALS 2017 NINDS 1F31NS100302-01 Determining the role of RNA-based factors in RAN translation of C9ALS/FTD-associated GGGGCC repeats GREEN, KATELYN UNIVERSITY OF MICHIGAN MI $40,474
ALS 2017 NINDS 1F30NS100595-01 Single-molecule resolution of RNA editing of mRNAs: visualizing GRIA2 editing in situ in ALS MELLIS, IAN UNIVERSITY OF PENNSYLVANIA PA $44,044
ALS 2017 NINDS 5R01NS091722-02 Molecular phenotyping of cortical cell types in multiple rodent models of ALS SCHMIDT, ERIC ROCKEFELLER UNIVERSITY NY $370,781
ALS 2017 NINDS 5R01NS089616-03 Investigating disease Mechanisms in C9orf72-linked ALS/FTD WANG, JIOU JOHNS HOPKINS UNIVERSITY MD $354,375
ALS 2017 NINDS 5R01NS084089-06 Mechanisms of Neurodegeneration in ALS XIA, XU-GANG UNIVERSITY OF CENTRAL FLORIDA FL $314,775
ALS 2017 NINDS 5R01NS084486-04 Mitochondrial inter membrane space-IMS unfolded protein response in familial ALS GERMAIN, DORIS ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI NY $370,782
ALS 2017 NINDS 5K23NS083715-04 Molecular Imaging of Inflammation in Amyotrophic Lateral Sclerosis (ALS) ATASSI, NAZEM MASSACHUSETTS GENERAL HOSPITAL MA $201,960
ALS 2017 NIA 5R21AG050793-03 TrkB Receptor PET Tracer Development STEHOUWER, JEFFREY EMORY UNIVERSITY GA $234,000
ALS 2017 NINDS 5R01NS082304-04 Development of a Multi-Modal Neuroimaging Biomarker for Amyotrophic Lateral Scler FOERSTER, BRADLEY UNIVERSITY OF MICHIGAN MI $577,180
ALS 2017 NIA 5R01NS097545-02 Role of C9orf72 in Neurodegeneration BALOH, ROBERT CEDARS-SINAI MEDICAL CENTER CA $54,687
ALS 2017 NINDS 5R01NS097545-02 Role of C9orf72 in Neurodegeneration BALOH, ROBERT CEDARS-SINAI MEDICAL CENTER CA $328,126
ALS 2017 NINDS 5R01NS088689-04 Silencing C9or72 with rAAV Mediated RNAi BROWN, ROBERT UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $464,134
ALS 2017 NINDS 5R01NS089640-03 NAD metabolsim and mitochondrial dysfunction in ALS models VARGAS, MARCELO MEDICAL UNIVERSITY OF SOUTH CAROLINA SC $327,031
ALS 2017 NINDS 5R01NS073873-07 Identification of ALS associated genes using whole genome sequencing LANDERS, JOHN UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $691,507
ALS 2017 NINDS 5R01NS087227-05 Using RNA signatures for therapy development in neurodegeneration due to C9orf72 expansions LAGIER-TOURENNE, CLOTILDE MASSACHUSETTS GENERAL HOSPITAL MA $304,500
ALS 2017 NINDS 5R01NS089701-05 Redesign Rat Model for ALS Research ZHOU, HONGXIA UNIVERSITY OF CENTRAL FLORIDA FL $314,775
ALS 2017 NINDS 5R01NS091299-03 RNA dysregulation in neurodegeneration ZARNESCU, DANIELA UNIVERSITY OF ARIZONA AZ $321,921
ALS 2017 NINDS 5R21NS095273-02 Modulating the Nucleopathy caused by FUS Mutants of ALS HAYWARD, LAWRENCE UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $209,375
ALS 2017 NINDS 5R21NS096572-02 Development of mouse models for ALS5 and SPG11 DENG, HAN-XIANG NORTHWESTERN UNIVERSITY AT CHICAGO IL $193,125
ALS 2017 NINDS 5R21NS097749-02 Molecular neuropathology of TDP-43 proteinopathies LEE, EDWARD UNIVERSITY OF PENNSYLVANIA PA $201,250
ALS 2017 NINDS 5R21NS090205-02 Exploring and enhancing Karyopherin beta-2 disaggregate activity SHORTER, JAMES UNIVERSITY OF PENNSYLVANIA PA $236,398
ALS 2017 NINDS 5R21NS095256-02 Pathogenic role of the novel mitochondrial apoptotic protein PSAP in ALS CUI, MEI-ZHEN UNIVERSITY OF TENNESSEE KNOXVILLE TN $183,750
ALS 2017 NINDS 5R21NS098131-02 Gene Therapy for Upper Airway and Respiratory Insufficiency in an ALS Mouse Model ELMALLAH, MAI UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $209,375
ALS 2017 NINDS 5R03NS098228-02 Optimization of Bi-Pap and PEG intervention protocols for Amyotrophic Lateral Sclerosis MITCHELL, CASSIE GEORGIA INSTITUTE OF TECHNOLOGY GA $78,900
ALS 2017 NINDS 5R21NS093439-02 Cytohesins, ARF GTP'ases and Neurodegeneration KALB, ROBERT CHILDREN'S HOSP OF PHILADELPHIA PA $210,000
ALS 2017 NINDS 5R21NS098497-02 A new approach to modeling ALS based on TBK1 mutation in mice XU, ZUOSHANG UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $209,375
ALS 2017 NIGMS 1R35GM122524-01 RNA Processing Machines in Biology and Disease REED, ROBIN HARVARD MEDICAL SCHOOL MA $645,032
ALS 2017 NINDS 1SC2NS104275-01 Determination of cell death pathways activated in ALS YANG, WAN ST. JOHN'S UNIVERSITY NY $164,000
ALS 2017 NINDS 5R01NS090352-04 Misfolded ALS-linked Profilin-1: a novel therapeutic target BOSCO, DARYL UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $364,766
ALS 2017 NINDS 5R01NS098516-02 Mechanisms of HIPK2 in neurodegeneration HUANG, ERIC UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $346,719
ALS 2017 NINDS 5R01NS063964-08 TDP-43, RNA Metabolism, and ALS/FTD Pathology LINK, CHRISTOPHER UNIVERSITY OF COLORADO CO $417,196
ALS 2017 NIA 5R01NS097850-02 The Role of C9ORF72 Protein Function in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia ICHIDA, JUSTIN UNIVERSITY OF SOUTHERN CALIFORNIA CA $51,562
ALS 2017 NINDS 5R01NS097850-02 The Role of C9ORF72 Protein Function in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia ICHIDA, JUSTIN UNIVERSITY OF SOUTHERN CALIFORNIA CA $544,908
ALS 2017 NINDS 5R01NS074324-07 Neurodegeneration and Proteotoxicity Dissected in C. elegans and Mammals WANG, JIOU JOHNS HOPKINS UNIVERSITY MD $456,197
ALS 2017 NINDS 5R01NS092788-03 Modeling the progression of SOD1-linked motor neuron disease BORCHELT, DAVID UNIVERSITY OF FLORIDA FL $328,125
ALS 2017 NINDS 5R01NS097816-02 Understanding SOD1 Kinetics in Amyotrophic Lateral Sclerosis MILLER, TIMOTHY WASHINGTON UNIVERSITY MO $595,862
ALS 2017 NIA 5U01AG045390-04 Longitudinal Evaluation of Familial Frontotemporal Dementia Subjects (LEFFTDS) BOEVE, BRADLEY MAYO CLINIC ROCHESTER MN $1,697,691
ALS 2017 NINDS 5U01AG045390-04 Longitudinal Evaluation of Familial Frontotemporal Dementia Subjects (LEFFTDS) BOEVE, BRADLEY MAYO CLINIC ROCHESTER MN $1,697,691
ALS 2017 NINDS 5F31NS092340-03 Defining Motor Neuron-Specific miRNAs in ALS LAWLER, MARIAH WASHINGTON UNIVERSITY MO $30,774
ALS 2017 NINDS 1R01NS100835-01 NGF and RAGE-p75NTR signaling in models of amyotrophic lateral sclerosis PEHAR, MARIANA MEDICAL UNIVERSITY OF SOUTH CAROLINA SC $327,031
ALS 2017 NINDS 1R01NS100859-01 Delineating Physiologic Mechanisms of Swallowing impairment and Decline in ALS PLOWMAN, EMILY UNIVERSITY OF FLORIDA FL $348,690
ALS 2017 NINDS 1R01NS100815-01 Using HTS to Identify Inhibitors of R155H-p97/VCP Mutant to treat IBMPFD/ALS CHOU, TSUI-FEN LA BIOMED RES INST/ HARBOR UCLA MED CTR CA $329,000
ALS 2017 NIA 5R01NS094239-02 Nucleocytoplasmic transport and nuclear pore disruption in ALS/FTD ROTHSTEIN, JEFFREY JOHNS HOPKINS UNIVERSITY MD $137,664
ALS 2017 NINDS 5R01NS094239-02 Nucleocytoplasmic transport and nuclear pore disruption in ALS/FTD ROTHSTEIN, JEFFREY JOHNS HOPKINS UNIVERSITY MD $511,326
ALS 2017 NINDS 5R01NS089742-04 C9ORF72 in Motor System Biology and ALS EGGAN, KEVIN HARVARD UNIVERSITY MA $454,237
ALS 2017 NINDS 5F30NS092262-03 Investigating V1 interneuron subtype diversity using embryonic stem cells HOANG, PHUONG COLUMBIA UNIVERSITY HEALTH SCIENCES NY $49,044
ALS 2017 NINDS 5R01NS091110-03 Treatment of ALS based on transplantation of glial restricted progenitors WALCZAK, PIOTR JOHNS HOPKINS UNIVERSITY MD $352,444
ALS 2017 NINDS 5R01NS088578-04 Developing ASO Therapy for Repeat Expanded C9orf72 ALS-FTD RAVITS, JOHN UNIVERSITY OF CALIFORNIA SAN DIEGO CA $428,588
ALS 2017 NINDS 1R03NS101334-01 Alpha-Tubulin Mutation and Motor Neuron Disease KIAEI, MAHMOUD UNIV OF ARKANSAS FOR MED SCIS AR $74,500
ALS 2017 NINDS 1R01NS097679-01A1 Mitochondrial dynamics for the maintenance of neuromuscular junctions during aging and in ALS WANG, XINGLONG CASE WESTERN RESERVE UNIVERSITY OH $410,577
ALS 2017 OD 5U54OD020351-03 5026 Project 6 - Amyotrophic Lateral Sclerosis Project LUTZ, CATHLEEN JACKSON LABORATORY ME $118,157
ALS 2017 NINDS 1R21NS101673-01 Identification of MicroRNA and Proteomics in immune cells and plasma in ALS BUTOVSKY, OLEG BRIGHAM AND WOMEN'S HOSPITAL MA $283,989
ALS 2017 NINDS 3R01NS081303-04S1 Cellular and Molecular Mechanisms of FUS-related Amyotrophic Lateral Sclerosis PANDEY, UDAI UNIVERSITY OF PITTSBURGH AT PITTSBURGH PA $1
ALS 2017 NINDS 5R01NS089604-04 TDP-43 and Mitochondrial Dysfunction in ALS WANG, XINGLONG CASE WESTERN RESERVE UNIVERSITY OH $346,719
ALS 2017 NINDS 5F30NS093682-03 Evolution of Pathologic RNA-Protein Aggregates in Motor Neuron Disease WHEELER, JOSHUA UNIVERSITY OF COLORADO CO $36,331
ALS 2017 NIDCD 5R03DC015075-02 Tongue- and Jaw-Specific Contributions to Vowel Acoustic Changes: Towards a Mechanistic Model of Intelligibility Loss and Recovery in Dysarthria MEFFERD, ANTJE VANDERBILT UNIVERSITY MEDICAL CENTER TN $158,000
ALS 2017 NCATS 5U54NS092091-04 6482 Project 1 BENATAR, MICHAEL UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $88,836
ALS 2017 NINDS 5U54NS092091-04 6482 Project 1 BENATAR, MICHAEL UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $158,609
ALS 2017 NCATS 5U54NS092091-04 6483 Project 2 BENATAR, MICHAEL UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $211,412
ALS 2017 NINDS 5U54NS092091-04 6483 Project 2 BENATAR, MICHAEL UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $377,454
ALS 2017 NCATS 5U54NS092091-04 6484 Pilot Demonstration BENATAR, MICHAEL UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $26,343
ALS 2017 NINDS 5U54NS092091-04 6484 Pilot Demonstration BENATAR, MICHAEL UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $47,032
ALS 2017 NCATS 5U54NS092091-04 6486 Admin Unit BENATAR, MICHAEL UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $93,474
ALS 2017 NINDS 5U54NS092091-04 6486 Admin Unit BENATAR, MICHAEL UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $166,889
ALS 2017 NIGMS 1U01GM117175-01A1 High-Content Screening to identify small molecules for refolding SOD1 mutants FANG, SHENGYUN UNIVERSITY OF MARYLAND BALTIMORE MD $303,207
ALS 2017 NINDS 2R01NS078398-06 Using motor neuron specific miRNA to understand and develop novel therapeutics for motor neuron disease MILLER, TIMOTHY WASHINGTON UNIVERSITY MO $492,369
ALS 2017 NINDS 5R01NS064131-09 Developing neuroprotective strategies for proteinopathy KRAEMER, BRIAN SEATTLE INST FOR BIOMEDICAL/CLINICAL RES WA $295,313
ALS 2017 NIEHS 1K23ES027221-01A1 Impact of Geospatial Factors and Environmental Pollutants on Amyotrophic Lateral Sclerosis in the State of Michigan GOUTMAN, STEPHEN UNIVERSITY OF MICHIGAN MI $201,525
ALS 2017 NINDS 5R37NS040389-14 Molecular Genetic Characterization of SCA8 RANUM, LAURA UNIVERSITY OF FLORIDA FL $626,676
ALS 2017 NINDS 5R01NS085207-05 ALS/FTD mutant C9orf72-induced genetic and nuclear pathology in iPS cell models ROTHSTEIN, JEFFREY JOHNS HOPKINS UNIVERSITY MD $354,375
ALS 2017 NIA 1R01NS098243-01A1 Mechanistic studies and therapeutics for ALS-FTD linked to UBQLN2 mutations MONTEIRO, MERVYN UNIVERSITY OF MARYLAND BALTIMORE MD $88,124
ALS 2017 NINDS 1R01NS098243-01A1 Mechanistic studies and therapeutics for ALS-FTD linked to UBQLN2 mutations MONTEIRO, MERVYN UNIVERSITY OF MARYLAND BALTIMORE MD $415,440
ALS 2017 NINDS 5R01NS092067-03 Regulation of glutamate transport in astrocyte subtypes and in ALS ROBINSON, MICHAEL CHILDREN'S HOSP OF PHILADELPHIA PA $466,052
ALS 2017 NIA 1R01NS100008-01A1 Deciphering the role of ER stress in ALS pathogenesis caused by UBQLN2 mutations MONTEIRO, MERVYN UNIVERSITY OF MARYLAND BALTIMORE MD $547,956
ALS 2017 NINDS 5R01NS087070-04 Cyclic EphA4 peptide antagonists for neuroprotection in ALS PASQUALE, ELENA SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE CA $689,360
ALS 2017 NIA 5R01NS098819-02 Molecular Characterization of ALS/FTD in a novel C9orf72 BAC mouse model. RANUM, LAURA UNIVERSITY OF FLORIDA FL $135,401
ALS 2017 NINDS 5R01NS098819-02 Molecular Characterization of ALS/FTD in a novel C9orf72 BAC mouse model. RANUM, LAURA UNIVERSITY OF FLORIDA FL $704,375
ALS 2017 NIGMS 5F32GM113446-03 Therapeutic genome editing for amyotrophic lateral sclerosis GAJ, THOMAS UNIVERSITY OF CALIFORNIA BERKELEY CA $60,990
ALS 2017 NIA 5R01NS097542-02 RNA decay in amyotrophic lateral sclerosis and frontotemporal lobar degeneration BARMADA, SAMI UNIVERSITY OF MICHIGAN MI $387,500
ALS 2017 NIGMS 5R01GM056350-19 Exploring the toxicity of aggregates associated with protein-misfolding diseases LIEBMAN, SUSAN UNIVERSITY OF NEVADA RENO NV $371,610
ALS 2017 NINDS 5R01NS088645-03 Etiological Linkage of DNA Damage/Repair Deficiency in Neurodegenerative Diseases HEGDE, MURALIDHAR METHODIST HOSPITAL RESEARCH INSTITUTE TX $344,594
ALS 2017 NINDS 1R21NS100055-01A1 Molecular mechanisms of C9orf72 and Matrin 3 interaction in ALS PANDEY, UDAI UNIVERSITY OF PITTSBURGH AT PITTSBURGH PA $232,313
ALS 2017 NINDS 5F32NS092417-03 Identifying the mechanisms of neuronal fate commitment during direct conversion GALLOWAY, KATE UNIVERSITY OF SOUTHERN CALIFORNIA CA $60,990
ALS 2017 NIDCD 1F31DC015941-01A1 Anatomic and biomechanic biomarkers of lingual impairment in person with ALS PERRY, BRIDGET MGH INSTITUTE OF HEALTH PROFESSIONS MA $34,682
ALS 2017 NINDS 5P01NS084974-04 6281 Administrative Core PETRUCELLI, LEONARD MAYO CLINIC JACKSONVILLE FL $243,227
ALS 2017 NINDS 5P01NS084974-04 6282 Project 1: Molecular markers and phenotypic heterogeneity in c9FTD/ALS. BOYLAN, KEVIN MAYO CLINIC JACKSONVILLE FL $154,437
ALS 2017 NINDS 5P01NS084974-04 6283 Project 2: RAN translation and RNA-binding protein sequestration in c9FTD/ALS PETRUCELLI, LEONARD MAYO CLINIC JACKSONVILLE FL $48,645
ALS 2017 NINDS 5P01NS084974-04 6284 Project 3: Neuropathology of the multi-proteinopathy of c9FTD/ALS. DICKSON, DENNIS MAYO CLINIC JACKSONVILLE FL $86,081
ALS 2017 NINDS 5P01NS084974-04 6285 Core B: Clinical and Genetics Core BOYLAN, KEVIN MAYO CLINIC JACKSONVILLE FL $306,724
ALS 2017 NINDS 5P01NS084974-04 6286 Core C: Neuropathology DICKSON, DENNIS MAYO CLINIC JACKSONVILLE FL $147,739
ALS 2017 NINDS 1F31NS100401-01A1 The role of p62/SQSTM1 in the pathogenesis of motor neuron disease CUNNINGHAM, KATHLEEN JOHNS HOPKINS UNIVERSITY MD $44,044
ALS 2017 NINDS 5R21NS099977-02 SMN dysfunction in FUS-dependent ALS PELLIZZONI, LIVIO COLUMBIA UNIVERSITY HEALTH SCIENCES NY $200,000
ALS 2017 NINDS 5R21NS095299-02 The role of G3BP1 in mutant SOD1-mediated familial ALS GAL, JOZSEF UNIVERSITY OF KENTUCKY KY $188,125
ALS 2017 NIA 1R01NS101986-01 Induced Pluripotent Stem Cells and Drosophila Models of C9ORF72-Related FTD/ALS GAO, FEN-BIAO UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $99,662
ALS 2017 NINDS 1R01NS101986-01 Induced Pluripotent Stem Cells and Drosophila Models of C9ORF72-Related FTD/ALS GAO, FEN-BIAO UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $370,176
ALS 2017 NINDS 5R01NS089586-02 Role of Oligodendroglia in the Pathogenesis of ALS KANG, SHIN TEMPLE UNIV OF THE COMMONWEALTH PA $340,104
ALS 2017 NINDS 5R21NS099766-02 Endogenous petides as markers of abnormal SOD-1 protein in familial and sporadic ALS GERTSMAN, ILYA UNIVERSITY OF CALIFORNIA SAN DIEGO CA $193,128
ALS 2017 NINDS 5K22NS091314-04 Epigenetics In Neurodegenerative Disease: Targeting Histone Modifications in ALS TORRENTE, MARIANA BROOKLYN COLLEGE NY $153,370
ALS 2017 NINDS 5R01NS099638-02 Investigation of ALS caused by mutant CHCHD10 SIDDIQUE, TEEPU NORTHWESTERN UNIVERSITY AT CHICAGO IL $507,347
ALS 2017 NINDS 5R01NS050452-12 An In Vitro Model of Stem Cell Innervation of Myotubes HICKMAN, JAMES UNIVERSITY OF CENTRAL FLORIDA FL $481,578
ALS 2017 NIA 5R01NS099280-02 Hexanucleotide repeat translation in ALS and Frontotemporal Dementia TODD, PETER UNIVERSITY OF MICHIGAN MI $83,050
ALS 2017 NINDS 5R01NS099280-02 Hexanucleotide repeat translation in ALS and Frontotemporal Dementia TODD, PETER UNIVERSITY OF MICHIGAN MI $391,515
ALS 2017 NINDS 5R00NS091538-04 C9orf72 hexanucleotide repeat expansion caused neurodegeneration in ALS and FTD SUN, SHUYING JOHNS HOPKINS UNIVERSITY MD $243,760
ALS 2017 NIDCD 3R01DC013547-04S1 Speech Movement Classification for Assessing and Treating ALS GREEN, JORDAN MGH INSTITUTE OF HEALTH PROFESSIONS MA $93,248
ALS 2017 NCATS 5U54NS092089-04 6206 Project 1 - The Frontotemporal Lobar Degeneration Clinical Research Consortium BOXER, ADAM UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $119,455
ALS 2017 NINDS 5U54NS092089-04 6206 Project 1 - The Frontotemporal Lobar Degeneration Clinical Research Consortium BOXER, ADAM UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $119,455
ALS 2017 NIDCD 3R01DC009899-05S1 Restoring Communication with an Intracortical Neural Interface System HOCHBERG, LEIGH MASSACHUSETTS GENERAL HOSPITAL MA $25,624
ALS 2017 NCATS 1R43TR002047-01 Software Platform to Stratify Patients for Treatment Arm Randomization in Human Clinical Trials using Patient-Level Predictive Models ENNIST, DAVID ORIGENT DATA SCIENCES, INC. VA $224,796
ALS 2017 NIGMS 5F31GM119249-02 Investigation of a novel protein complex that couples regulation of lysosomal function to intracellular nutrient availability AMICK, JOSEPH YALE UNIVERSITY CT $28,680
ALS 2017 RMAP 1DP2NS106664-01 A Human Stem Cell-Derived Neuromuscular Junction Model for Amyotrophic Lateral Sclerosis WAINGER, BRIAN MASSACHUSETTS GENERAL HOSPITAL MA $2,565,000
ALS 2017 NINDS 5U54NS091046-04 5987 Data Generation Core - Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells THOMPSON, LESLIE UNIVERSITY OF CALIFORNIA-IRVINE CA $904,441
ALS 2017 RMAP 5U54NS091046-04 5987 Data Generation Core - Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells THOMPSON, LESLIE UNIVERSITY OF CALIFORNIA-IRVINE CA $235,310
ALS 2017 NIGMS 5R01GM120607-02 Genomic profiling of pathological R-loop formation in human diseases. CHEDIN, FREDERIC UNIVERSITY OF CALIFORNIA AT DAVIS CA $314,000
ALS 2017 NINDS 5R01NS100023-02 Deconstructing the cellular and molecular basis of SBMA motor neuron disease: From mechanism to therapy LA SPADA, ALBERT UNIVERSITY OF CALIFORNIA SAN DIEGO CA $476,403
ALS 2017 NINDS 5R44NS089423-03 Development of an information-rich assay for C9ORF72 as a test for ALS and FTD BRAM, ERAN ASURAGEN, INC. TX $759,812
ALS 2017 NINDS 1R01NS102414-01 CAT-tails: A Novel Type of Protein Modification Implicated in Neurodegeneration COX, GREGORY JACKSON LABORATORY ME $678,247
ALS 2017 NIDCD 1K24DC016312-01 Prolonging Functional Speech in Persons with Amyotrophic Lateral Sclerosis: A Real-Time Virtual Vocal Tract GREEN, JORDAN MGH INSTITUTE OF HEALTH PROFESSIONS MA $189,841
ALS 2017 NINDS 1K08NS102396-01 Unraveling the mechanisms of motor neuron degeneration if Spinocerebellar Ataxia, type 1 ORENGO, JAMES BAYLOR COLLEGE OF MEDICINE TX $188,431
ALS 2017 NINDS 1R21NS102829-01 Elucidation of specific nucleocytoplasmic trafficking pathways that are disrupted in C9ORF72 ALS ZEIER, ZANE UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $230,250
ALS 2017 NIA 1K99AG056678-01 Comparative genomic approaches to improve iPSC-derived motor neuron models of ALS HO, RITCHIE CEDARS-SINAI MEDICAL CENTER CA $95,017
ALS 2017 NIDCD 1R15DC016383-01 A Systematic Investigation of Phonetic Complexity Effects on Articulatory Motor Performance in Progressive Dysarthria KURUVILLA, MILI UNIVERSITY OF MISSOURI-COLUMBIA MO $427,189
ALS 2017 NINDS 1R01NS101895-01A1 An in vivo approach to understanding mutant PFN1 toxicity on motor neurons XU, ZUOSHANG UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $335,000
ALS 2017 NINDS 1R21NS097989-01A1 Using PNAs to Elucidate the Role of G-quadruplex and Hairpin Structures in ALS/FTD through a Combined Biophysical and Computational Approach EVANSECK, JEFFREY DUQUESNE UNIVERSITY PA $218,165
ALS 2017 NINDS 1R21NS101616-01A1 Understanding the role of minor spliceosome in the pathogenesis of amyotrophic lateral sclerosis KANADIA, RAHUL UNIVERSITY OF CONNECTICUT STORRS CT $231,458
ALS 2017 NIA 1R21NS101661-01A1 Drosophila models for ubiquilin-associated ALS TIBBETTS, RANDAL UNIVERSITY OF WISCONSIN-MADISON WI $198,244
ALS 2017 NINDS 1F31NS103360-01 The Nuclear Pore Complex in ALS/FTD GRIMA, JONATHAN JOHNS HOPKINS UNIVERSITY MD $44,044
ALS 2017 NINDS 1F31NS101966-01A1 Retromer dysfunction in amyotrophic lateral sclerosis PEREZ-TORRES, EDUARDO COLUMBIA UNIVERSITY HEALTH SCIENCES NY $43,576
ALS 2017 NCATS 1UG3NS105703-01 Development of a Microphysiological Organ-on-Chip System to Model Amyotrophic SVENDSEN, CLIVE CEDARS-SINAI MEDICAL CENTER CA $598,655
ALS 2017 NINDS 1UG3NS105703-01 Development of a Microphysiological Organ-on-Chip System to Model Amyotrophic SVENDSEN, CLIVE CEDARS-SINAI MEDICAL CENTER CA $625,000
ALS 2017 NIDCD 3R43DC015192-01S1 Superior laryngeal nerve stimulation for the treatment of neurogenic dysphagia in an animal model of amyotrophic lateral sclerosis KHODAPARAST, NAVID NUVIANT MEDICAL INC. TX $41,095
ALS 2017 NIEHS 3R01ES024064-03S1 Environmental Metals, Excitotoxicity and ALS ATCHISON, WILLIAM MICHIGAN STATE UNIVERSITY MI $66,095
ALS 2017 NIA 1R44AG059278-01 PET Imaging Agents for the in vivo Detection of TDP-43 REITZ, ALLEN FOX CHASE CHEMICAL DIVERSITY CENTER, INC PA $745,412
ALS 2017 NINDS 3R01NS074324-06A1S1 Neurodegeneration and Proteotoxicity Dissected in C. elegans and Mammals WANG, JIOU JOHNS HOPKINS UNIVERSITY MD $17,019
ALS 2017 NHLBI 4R42HL132735-02 Jamboxx: Interactive Respiratory Therapy through Music and Gaming DICESARE, MICHAEL MY MUSIC MACHINES, INC. NY $999,500
ALS 2017 NIA 1RF1AG057338-01 A systems approach to uncover upstream activators and common downstream pathways of neurodegeneration in a Drosophila model DUBNAU, JOSHUA STATE UNIVERSITY NEW YORK STONY BROOK NY $3,588,826
ALS 2017 NINDS 3F32NS093938-01S1 Genetic and Functional Characterization of Astrocyte Subtypes in the Spinal Cord GLENN, THOMAS SALK INSTITUTE FOR BIOLOGICAL STUDIES CA $200
ALS 2017 NINDS 1R01NS104022-01 Expanding the chemical diversity of therapeutic oligonucleotides to treat neurodegenerative disorders KHVOROVA, ANASTASIA UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $664,751
ALS 2017 NIA 1UG3NS103870-01 Whole genome sequencing consortium on Frontotemporal dementia with underlying TDP-43 pathology RADEMAKERS, ROSA MAYO CLINIC JACKSONVILLE FL $961,469
ALS 2017 NINDS 1K08NS104273-01 FG-nucleoporins and nuclear transport disruption in C9ORF72-ALS/FTD HAYES, LINDSEY JOHNS HOPKINS UNIVERSITY MD $199,800
ALS 2017 NINDS 3R01NS097850-01S1 The Role of C9ORF72 Protein Function in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia ICHIDA, JUSTIN UNIVERSITY OF SOUTHERN CALIFORNIA CA $45,347
ALS 2017 NINDS 7R01NS073829-07 Study on Neurodegeneration using TDP-43 Transgenic Rats ZHOU, HONGXIA UNIVERSITY OF CENTRAL FLORIDA FL $311,202
ALS 2017 NINDS 7R01NS095962-02 Study on hnRNPA1 Pathobiology in ALS XIA, XU-GANG UNIVERSITY OF CENTRAL FLORIDA FL $314,775
ALS 2017 NINDS 4R00NS091486-03 Nucleocentric molecular characterization of C9orf72 NRE-linked neurodegeneration HAEUSLER, AARON THOMAS JEFFERSON UNIVERSITY PA $248,999
ALS 2017 NINDS 2R01NS075839-06A1 Using human IPS cells to study fate, function and neurodegenerative disease IACOVITTI, LORRAINE THOMAS JEFFERSON UNIVERSITY PA $378,827
ALS 2017 NINDS 2R01NS027036-30 Disease mechanism in ALS and frontotemporal dementia CLEVELAND, DON LUDWIG INSTITUTE FOR CANCER RES LTD CA $661,854
ALS 2017 NIA 4R00AG047335-03 The Role of Cortical Projection Neurons Susceptible to Progressive Degeneration wIth Aging MAROOF, ASIF UNIVERSITY OF TEXAS SAN ANTONIO TX $248,999
ALS 2017 NIA 1R43AG058325-01 Preserving cellular aspects of aging in patient-specific models of ALS ALWORTH, SAMUEL ACURASTEM, INC. CA $224,935
ALS 2017 NINDS 1F31NS101807-01A1 Defining the molecular basis of substrate selection by diverse Hsp104 homologues MARCH, ZACHARY UNIVERSITY OF PENNSYLVANIA PA $44,044
ALS 2017 NIEHS 3R01ES024064-03S2 Environmental Metals, Excitotoxicity and ALS ATCHISON, WILLIAM MICHIGAN STATE UNIVERSITY MI $6,917
ALS 2017 NINDS 3R01NS097850-01S2 The Role of C9ORF72 Protein Function in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia ICHIDA, JUSTIN UNIVERSITY OF SOUTHERN CALIFORNIA CA $12,908
ALS 2017 NCATS 3U54NS092091-04S1 Clinical Research in ALS & related disorders for Therapeutic Development (CREATE) BENATAR, MICHAEL UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $299,785
ALS 2017 NCATS 3U54NS092091-04S2 Clinical Research in ALS & related disorders for Therapeutic Development (CREATE) BENATAR, MICHAEL UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $297,681
ALS 2017 NINDS 1R56NS103195-01 Early development of small molecule neuroprotectants LASMEZAS, CORINNE SCRIPPS FLORIDA FL $666,166
ALS 2017 NINDS 1R56NS098520-01A1 A Multimodal MRI Approach for Probing ALS Pathophysiology and Neurorepair BULTE, JEFF JOHNS HOPKINS UNIVERSITY MD $424,174
ALS 2017 NINDS 2R56NS073776-06A1 FUS Gain-of-Function Mechanisms in Animal and Cellular Models of ALS SHNEIDER, NEIL COLUMBIA UNIVERSITY HEALTH SCIENCES NY $556,796
ALS 2017 NIA 3R01AG031867-09S1 IBMPFD Mutations Impair Protein Degradation WEIHL, CONRAD WASHINGTON UNIVERSITY MO $152,500
ALS 2017 NINDS 4R33NS082618-03 High-Throughput Modeling of ALS Using iPSC-Derived Neural Tube Microarrays ASHTON, RANDOLPH UNIVERSITY OF WISCONSIN-MADISON WI $394,400
ALS 2017 NIEHS 1ZIAES049005-26 Lead And Other Neurotoxins As Risk Factors For Amyotrophic Lateral Sclerosis SANDLER, DALE NIH $107,849
ALS 2017 NIEHS 1ZIAES049028-21 Environmental Exposures And Risk For Cancer and Chronic Diseases In Adults SANDLER, DALE NIH $117,960
ALS 2017 NICHD 1ZIAHD008892-09 Mechanisms of Motor Neuron Disease KALER, STEPHEN NIH $276,121
ALS 2017 NICHD 1ZIAHD008966-01 The neuronal stress response in neurodegenerative disease and pain LE PICHON, CLAIRE NIH $1,392,971
ALS 2017 NIA 1ZIAAG000933-10 Genetic etiology of Amyotrophic Lateral Sclerosis TRAYNOR, BRYAN NIH $820,911
ALS 2017 NIA 1ZIAAG000934-09 Genetic etiology of Fronto-Temporal Dementia TRAYNOR, BRYAN NIH $547,274
ALS 2017 NCATS 1ZIATR000317-01 p97 inhibitors for treatment of IBMPFD/ALS SIMEONOV, ANTON NIH $135,676
ALS 2017 NCI 1ZIABC011501-05 Regulation and functional effects of localized RNAs MILI, STAVROULA NIH $903,696
ALS 2017 NINDS 1ZIANS003038-11 Studies of Hereditary Neurological Disease: Disease Mechanisms FISCHBECK, KENNETH NIH $1,560,848
ALS 2017 NINDS 1ZIANS003146-03 Natural history and biomarker discovery in C9orf72 Amyotrophic lateral sclerosis and frontotemporal dementia FLOETER, MARY KAY NIH $1,581,376
ALS 2017 NIA 1R56AG054898-01 Dysregulated cholinergic transmission contributes to aging of the lower motor system VALDEZ, GREGORIO VIRGINIA POLYTECHNIC INST AND ST UNIV VA $394,011


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