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RCDC

Project Listing by Category


Back to Estimates of Funding for Various Research, Condition, and Disease Categories (RCDC) Click the column headings to sort project listings.
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CategoryFYFunding ICProject NumberSub Project #Project TitlePI NameOrg NameState / CountryAmount
Orphan Drug 2016 NINDS 3R01NS075075-05S1 Determinants of Neurodegenerative Decline in Primary Progressive Aphasia ROGALSKI, EMILY NORTHWESTERN UNIVERSITY AT CHICAGO IL $50,000
Orphan Drug 2016 NCI 5R01CA154739-05 Targeting Slc16a/Mct Lactate Transporters in Cancer Therapeutics CLEVELAND, JOHN H. LEE MOFFITT CANCER CTR & RES INST FL $598,617
Orphan Drug 2016 NCI 5R03CA182552-02 A novel regimen to target both pancreatic cancer K-ras and antiapoptotic proteins LI, FENGZHI ROSWELL PARK CANCER INSTITUTE CORP NY $84,900
Orphan Drug 2016 NIGMS 1P20GM109024-01A1 5953 Animal Core Facility GUO, BIN NORTH DAKOTA STATE UNIVERSITY ND $407,028
Orphan Drug 2016 NIGMS 1P20GM109024-01A1 5955 Effects of salinomycin and binding target proteins in pancreatic cancer WU, ERXI NORTH DAKOTA STATE UNIVERSITY ND $232,725
Orphan Drug 2016 NIGMS 1P20GM109024-01A1 5956 Combination Therapy: Targeting Pancreatic Cancer with a ROS Inducer and Gemcitabine REINDL, KATIE NORTH DAKOTA STATE UNIVERSITY ND $217,500
Orphan Drug 2016 NIGMS 1P20GM109024-01A1 5957 Development of Monoclonal Antibodies to Inhibit RAGE Activation in Pancreatic Cancer tumors LECLERC, ESTELLE NORTH DAKOTA STATE UNIVERSITY ND $232,725
Orphan Drug 2016 NIGMS 1P20GM109094-01A1 6065 Fatty Acid Synthesis, Surface Molecules, and Immune Evasion PAUL, KIMBERLY CLEMSON UNIVERSITY SC $240,431
Orphan Drug 2016 NINDS 4R44NS071879-04 Advancing a Glioma Immunotherapy EMERICH, DWAINE IN CYTU, INC. RI $879,408
Orphan Drug 2016 NHLBI 4K24HL111316-04 Forging a road to personalized medicine in interstitial lung diseases FLAHERTY, KEVIN UNIVERSITY OF MICHIGAN MI $181,756
Orphan Drug 2016 NHLBI 4R01HL115041-04 Novel Methods for the Conduct of Clinical Trials MERKEL, PETER UNIVERSITY OF PENNSYLVANIA PA $590,018
Orphan Drug 2016 NIAID 4R37AI048793-16 Immunogenetic Mechanisms of Vaccine Response POLAND, GREGORY MAYO CLINIC ROCHESTER MN $496,999
Orphan Drug 2016 NHLBI 5R01HL119960-04 Rituximab Therapy in Patients with IPF DUNCAN, STEVEN UNIVERSITY OF ALABAMA AT BIRMINGHAM AL $673,599
Orphan Drug 2016 NINDS 4R01NS073870-06 Defining the role of BRAF in glioma initiation and maintenance HOLMEN, SHERI UNIVERSITY OF UTAH UT $325,938
Orphan Drug 2016 NICHD 4P01HD032652-18 5389 In Vivo Lentiviral Gene Therapy for Hurler Syndrome WHITLEY, CHESTER UNIVERSITY OF MINNESOTA MN $240,173
Orphan Drug 2016 NICHD 4P01HD032652-18 5390 AAV Mediated Gene Therapy to the CNS for MPS I WHITLEY, CHESTER UNIVERSITY OF MINNESOTA MN $250,166
Orphan Drug 2016 NICHD 4P01HD032652-18 5395 Research Animal Care and Medicine WHITLEY, CHESTER UNIVERSITY OF MINNESOTA MN $132,868
Orphan Drug 2016 NINDS 4U01NS082328-03 Neural Stem Cell Mediated CE-CPT11 Therapy for Neuroblastoma ABOODY, KAREN BECKMAN RESEARCH INSTITUTE/CITY OF HOPE CA $1,238,896
Orphan Drug 2016 NCATS 5UH3TR000961-03 Therapeutic Strategy for LAM (Lymphangioleiomyomatosis) EISSA, N BAYLOR COLLEGE OF MEDICINE TX $1,482,013
Orphan Drug 2016 NCI 1K22CA197014-01 Analysis and Therapeutic Targeting Non-proteolytic Protein Ubiquitination in Diffuse Large B Cell Lymphoma YANG, YIBIN RESEARCH INST OF FOX CHASE CAN CTR PA $194,616
Orphan Drug 2016 NCI 1R35CA197463-01 Discovery and Characterization of New Human Cancer Viruses MOORE, PATRICK UNIVERSITY OF PITTSBURGH AT PITTSBURGH PA $916,710
Orphan Drug 2016 NCI 1R35CA197566-01 Mechanisms governing metastatic dormancy and reactivation GIANCOTTI, FILIPPO UNIVERSITY OF TX MD ANDERSON CAN CTR TX $959,998
Orphan Drug 2016 NIAID 5R01AI098302-03 Development of a topical malaria vaccine. NARDIN, ELIZABETH NEW YORK UNIVERSITY SCHOOL OF MEDICINE NY $676,165
Orphan Drug 2016 NIAID 4R01AI025038-24 Leishmania antigens defined by human immune responses REED, STEVEN INFECTIOUS DISEASE RESEARCH INSTITUTE WA $405,674
Orphan Drug 2016 NIAID 4R01AI095178-05 T cell immunity to Plasmodium sporozoite immunization HARTY, JOHN UNIVERSITY OF IOWA IA $423,281
Orphan Drug 2016 NIAID 5UM1AI069421-10 GHESKIO HIV Clinical Trial Unit PAPE, JEAN GHESKIO CENTER HAITI $1,110,670
Orphan Drug 2016 NIAID 5R01AI095499-03 Chemical Tools for the Study of Dengue Virus Entry YANG, PRISCILLA HARVARD MEDICAL SCHOOL MA $349,821
Orphan Drug 2016 NIAID 5R01AI114675-02 A High-Throughput Screen for Antiviral Inhibitors of the Alphavirus RNA Capping Enzyme GEISS, BRIAN COLORADO STATE UNIVERSITY CO $371,750
Orphan Drug 2016 NIAID 4R01AI068041-10 IFN-y-inducible GBPs in protective immunity to tuberculosis MACMICKING, JOHN YALE UNIVERSITY CT $369,157
Orphan Drug 2016 NHLBI 5K23HL119557-02 Improving Pain in Sickle Cell Patients With Targeted Antithrombotic Therapy SHAH, NIRMISH DUKE UNIVERSITY NC $157,929
Orphan Drug 2016 NIAID 5R01AI104488-03 A Nurse Case Management Intervention to Improve MDR-TB/HIV Coinfection Outcomes FARLEY, JASON JOHNS HOPKINS UNIVERSITY MD $630,379
Orphan Drug 2016 NIAID 5R21AI115358-02 Antigen metabolomics for mucosal-associated invariant T cells in tuberculosis HUANG, SHOUXIONG UNIVERSITY OF CINCINNATI OH $158,000
Orphan Drug 2016 NHLBI 5R42HL114206-03 Development of Novel Compounds for Treatment of Heart Arrhythmias in CPVT ABRAMSON, JONATHAN ELEX BIOTECH, LLC OR $749,998
Orphan Drug 2016 NCI 5R01CA176001-03 Mechanisms of Action for KCN1 in the Control of Uveal Melanoma Metastasis GROSSNIKLAUS, HANS EMORY UNIVERSITY GA $323,700
Orphan Drug 2016 NCI 5R01CA182461-03 Defining the impact of clonal evolution on chronic lymphocytic leukemia WU, CATHERINE DANA-FARBER CANCER INST MA $362,378
Orphan Drug 2016 NIAID 5R01AI075045-07 Resistance of Malaria Parasites to Artemisinin-Based Therapies ROSENTHAL, PHILIP UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $512,762
Orphan Drug 2016 NIAID 5R21AI109465-02 Targeting Heme Transporters for Improved Vaccines against Anthrax MARESSO, ANTHONY BAYLOR COLLEGE OF MEDICINE TX $198,125
Orphan Drug 2016 NIAID 5R21AI115383-02 Newcastle Disease Virus Vectored Vaccine against Poliomyelitis BELOV, GEORGIY UNIV OF MARYLAND, COLLEGE PARK MD $228,000
Orphan Drug 2016 NIAID 4R01AI089952-05 Transmission-blocking live vaccine for Chagas disease TARLETON, RICK UNIVERSITY OF GEORGIA GA $371,250
Orphan Drug 2016 NIAID 5R01AI094745-06 B cells and humoral immunity in tuberculosis CHAN, JOHN ALBERT EINSTEIN COLLEGE OF MEDICINE, INC NY $520,331
Orphan Drug 2016 NIAID 4R01AI099380-04 Exploring an Essential and Dangerous Pathway in Leishmania Parasites ZHANG, KAI TEXAS TECH UNIVERSITY TX $355,553
Orphan Drug 2016 NIAID 5R21AI112029-02 Nitric oxide-releasing cystic fibrosis therapeutics SCHOENFISCH, MARK UNIV OF NORTH CAROLINA CHAPEL HILL NC $185,401
Orphan Drug 2016 NHLBI 5R01HL071670-12 Arrhythmia Mechanisms in Sarcomeric Cardiomyopathies KNOLLMANN, BJORN VANDERBILT UNIVERSITY TN $78,019
Orphan Drug 2016 NHLBI 5R01HL125228-02 Mineralocorticoid receptor and abdominal aortic aneurysm GONG, MING UNIVERSITY OF KENTUCKY KY $519,619
Orphan Drug 2016 NIAID 4R01AI095309-04 Mucosal live vector vaccine against recurrent Clostridium difficile infections GALEN, JAMES UNIVERSITY OF MARYLAND BALTIMORE MD $383,750
Orphan Drug 2016 NIAID 4R01AI103280-04 FOSMIDOMYCIN RESISTANCE IN PLASMODIUM FALCIPARUM ODOM, AUDREY WASHINGTON UNIVERSITY MO $342,000
Orphan Drug 2016 NCI 4K22CA178269-03 Quantify treatment response in IDH1 mutant glioma patients with metabolic MRI ANDRONESI, OVIDIU MASSACHUSETTS GENERAL HOSPITAL MA $200,418
Orphan Drug 2016 NHLBI 5R01HL118390-03 Membrane Serine Protease Activities in Protease Activated Receptor Signaling ANTALIS, TONI UNIVERSITY OF MARYLAND BALTIMORE MD $383,750
Orphan Drug 2016 NHLBI 5R01HL106192-06 Mechanisms of endothelial barrier phenotypes in sickle cell disease OFORI-ACQUAH, SOLOMON UNIVERSITY OF PITTSBURGH AT PITTSBURGH PA $495,110
Orphan Drug 2016 NIAID 5UM1AI069521-10 Stellenbosch University Clinical Trials Unit (SUN-CTU) COTTON, MARK STELLENBOSCH UNIVERSITY TYGERBERG CAMPUS SO AFR $1,114,686
Orphan Drug 2016 NIMH 4R01MH093372-05 Epigenetic Regulation of Ube3a as a Treatment for Angelman Syndrome PHILPOT, BENJAMIN UNIV OF NORTH CAROLINA CHAPEL HILL NC $591,194
Orphan Drug 2016 NCI 4R01CA051210-24 Biochemical and molecular studies on NQO1. Design of less toxic Hsp90 inhibitors ROSS, DAVID UNIVERSITY OF COLORADO DENVER CO $312,983
Orphan Drug 2016 NHLBI 5K08HL121182-03 Comparative Effectiveness of N-said Treatment Versus No Treatment for PDA in Pret SLAUGHTER, JONATHAN RESEARCH INST NATIONWIDE CHILDREN'S HOSP OH $153,652
Orphan Drug 2016 NIAID 5UM1AI069422-10 South African Medical Research Council Clinical Trials Unit (MRC CTU) RAMJEE, GITA MEDICAL RESEARCH COUNCIL OF SOUTH AFRICA SO AFR $887,214
Orphan Drug 2016 NIAID 5UM1AI069432-10 The UCSD CD4 Collaborative Clinical Trial Unit BENSON, CONSTANCE UNIVERSITY OF CALIFORNIA SAN DIEGO CA $2,407,704
Orphan Drug 2016 NIAID 5R01AI077538-07 The roles of polyphosphate and acidocalcisomes in Trypanosoma brucei DOCAMPO, ROBERTO UNIVERSITY OF GEORGIA GA $375,000
Orphan Drug 2016 NIAID 5UM1AI069463-10 Clinical Trials Units for NIAID Networks (UM1) SANNE, IAN WITS HEALTH CONSORTIUM (PTY), LTD SO AFR $1,084,670
Orphan Drug 2016 NCI 4R01CA125187-09 Translational Optimization of Bone Regeneration in the Irradiated Mandible BUCHMAN, STEVEN UNIVERSITY OF MICHIGAN MI $244,741
Orphan Drug 2016 NINDS 4R01NS037918-18 Novel Lysosomal Enzyme Deficient in Batten Disease LOBEL, PETER RBHS-ROBERT WOOD JOHNSON MEDICAL SCHOOL NJ $313,031
Orphan Drug 2016 NIBIB 1R01EB020125-01A1 Theranostic nanoparticles for detection and treatment of pancreatic cancer MCNALLY, LACEY UNIVERSITY OF LOUISVILLE KY $70,388
Orphan Drug 2016 NIGMS 1R01EB020125-01A1 Theranostic nanoparticles for detection and treatment of pancreatic cancer MCNALLY, LACEY UNIVERSITY OF LOUISVILLE KY $320,000
Orphan Drug 2016 NIAID 5UM1AI069438-10 IMPACTA PERU CLINICAL TRIALS UNIT SANCHEZ, JORGE ASOCIACION CIVIL IMPACTA SALUD Y EDUCACN PERU $1,984,088
Orphan Drug 2016 NIAID 5R21AI115451-02 Synthetic neoglycopeptides as Chagas disease vaccine ALMEIDA, IGOR UNIVERSITY OF TEXAS EL PASO TX $223,770
Orphan Drug 2016 NIAID 5R21AI115534-02 Anaphylaxis and IgE heterogeneity KAWAKAMI, TOSHIAKI LA JOLLA INST FOR ALLERGY & IMMUNOLGY CA $210,082
Orphan Drug 2016 NIAID 4R37AI048071-15 Mapping Drug Resistance Genes in Plasmodium falciparum ANDERSON, TIM TEXAS BIOMEDICAL RESEARCH INSTITUTE TX $666,817
Orphan Drug 2016 NIAID 5R21AI107626-02 Phenoxyalkylimidazoles for use against persistent and replicating M. tuberculosis ODINGO, JOSHUA INFECTIOUS DISEASE RESEARCH INSTITUTE WA $207,000
Orphan Drug 2016 NCI 5R01CA128943-08 Molecular analysis and therapeutic targeting of PI3K signaling in thyroid cancer DI CRISTOFANO, ANTONIO ALBERT EINSTEIN COLLEGE OF MEDICINE, INC NY $396,625
Orphan Drug 2016 NIAID 5UM1AI069469-10 CAPRISA Clinical Trials Unit for AIDS/Tuberculosis Prevention and Treatment ABDOOL KARIM, QUARRAISHA CENTRE/AIDS PROGRAMME/RES/SOUTH AFRICA SO AFR $1,386,485
Orphan Drug 2016 NIAID 5UM1AI069418-10 Emory- Duke- Orlando- CDC (EmDOC) Clinical Trials Unit LENNOX, JEFFREY EMORY UNIVERSITY GA $2,052,913
Orphan Drug 2016 NIAID 5UM1AI069503-10 Terry Beirn CPCRA Clinical Trials Unit GORDIN, FRED GEORGE WASHINGTON UNIVERSITY DC $5,055,518
Orphan Drug 2016 NCI 4R01CA164178-04 A novel NKG2D-specific BiTE cancer immunotherapy SENTMAN, CHARLES DARTMOUTH COLLEGE NH $336,150
Orphan Drug 2016 NHLBI 5K08HL118367-03 ELUCIDATING THE ROLE OF KRUPPEL LIKE FACTOR 7 IN T CELL DEVELOPMENT SCHUETTPELZ, LAURA WASHINGTON UNIVERSITY MO $26,438
Orphan Drug 2016 NCI 4R01CA158415-05 Heterocellular 3D ovarian tumor arrays for imaging and mechanistic combinations HASAN, TAYYABA MASSACHUSETTS GENERAL HOSPITAL MA $367,787
Orphan Drug 2016 NCI 4F31CA180738-03 Genetic and pharmacological manipulation of system xc in pancreatic cancer BADGLEY, MICHAEL COLUMBIA UNIVERSITY HEALTH SCIENCES NY $43,120
Orphan Drug 2016 NCI 5R21CA191726-02 Therapeutic targeting of the B-cell lymphoma associated mutation MYD88-L265P SNYDER, GREG UNIVERSITY OF MARYLAND BALTIMORE MD $179,403
Orphan Drug 2016 NEI 5R01EY024249-02 A High Content Screening Approach for the Retinal Degenerative Diseases BERLINICKE, CYNTHIA JOHNS HOPKINS UNIVERSITY MD $405,000
Orphan Drug 2016 NEI 5R01EY024906-02 Transcriptional regulation of retinal mitochondrial function and cell cycle POCHE, ROSS BAYLOR COLLEGE OF MEDICINE TX $396,250
Orphan Drug 2016 NIAID 4R01AI103947-04 Lead optimization of DHODH inhibitors for malaria PHILLIPS, MARGARET UT SOUTHWESTERN MEDICAL CENTER TX $595,447
Orphan Drug 2016 NIAID 5R01AI100569-03 Optimizing ELQs for Treatment and Prevention of Malaria RISCOE, MICHAEL OREGON HEALTH & SCIENCE UNIVERSITY OR $613,423
Orphan Drug 2016 NCI 4P30CA006516-51 6047 Lymphoma and Myeloma SHIPP, MARGARET DANA-FARBER CANCER INST MA $93,216
Orphan Drug 2016 NCI 4P30CA006516-51 6051 Gynecologic Cancers BIRRER, MICHAEL MASSACHUSETTS GENERAL HOSPITAL MA $93,366
Orphan Drug 2016 NCI 4P30CA006516-51 6054 Gastrointestinal Malignancies FUCHS, CHARLES DANA-FARBER CANCER INST MA $93,190
Orphan Drug 2016 NCI 4P30CA006516-51 6056 Neuro-Oncology MARTUZA, ROBERT MASSACHUSETTS GENERAL HOSPITAL MA $93,279
Orphan Drug 2016 NCI 4P30CA006516-51 6061 Cancer Immunology DRANOFF, GLENN DANA-FARBER CANCER INST MA $93,190
Orphan Drug 2016 NCI 4F30CA176922-03 Recombinant Polymers for Transarterial Chemoembolization of Liver Cancer POURSAID, AZADEH UNIVERSITY OF UTAH UT $33,319
Orphan Drug 2016 NEI 5R21EY025074-02 Development of redox-active therapies for ischemic optic neuropathy LEVIN, LEONARD UNIVERSITY OF WISCONSIN-MADISON WI $229,500
Orphan Drug 2016 NCI 5R00CA168987-04 Discovering genomic rearrangements under selection in serious ovarian cancer SALZMAN, JULIA STANFORD UNIVERSITY CA $227,841
Orphan Drug 2016 NCI 5R21CA191544-02 CendR peptide-mediated enhancement of systemic oncolytic herpes virotherapy CRIPE, TIMOTHY RESEARCH INST NATIONWIDE CHILDREN'S HOSP OH $195,098
Orphan Drug 2016 NHLBI 5R41HL126456-02 HLS13-13 Albumin nanoparticle based technology to treat ARDS BACHMAIER, KURT CELL BIOLOGICS, INC. IL $344,039
Orphan Drug 2016 NHLBI 5R01HL121007-03 Identification and Functional characterization of a gene influencing LDL-C on 5q MITCHELL, BRAXTON UNIVERSITY OF MARYLAND BALTIMORE MD $391,718
Orphan Drug 2016 NCI 5R21CA191392-02 Identifying new drug targets to block K-Ras/Raf in pancreatic cancer. STORK, PHILIP OREGON HEALTH & SCIENCE UNIVERSITY OR $167,475
Orphan Drug 2016 NCI 5R21CA185274-02 Magnetic Micelles for Catheter-Directed Sorafenib Delivery to Liver Tumors KIM, DONG-HYUN NORTHWESTERN UNIVERSITY AT CHICAGO IL $201,623
Orphan Drug 2016 NCI 5R21CA186175-02 Targeting DCLK1 kinase activity in pancreatic cancer HOUCHEN, COURTNEY UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR OK $77,826
Orphan Drug 2016 NCI 5R21CA185804-02 Analysis of CTCs for Early Prediction of Response to Treatment in RCC WANG, SHAN STANFORD UNIVERSITY CA $174,544
Orphan Drug 2016 NHLBI 4R01HL105470-05 Improving Inhaled Drug Delivery with Self-dispersing Liquids GAROFF, STEPHEN CARNEGIE-MELLON UNIVERSITY PA $450,533
Orphan Drug 2016 NIAID 5R01AI114685-02 Hit-to-lead discovery for sleeping sickness via industry-academic partnership POLLASTRI, MICHAEL NORTHEASTERN UNIVERSITY MA $475,385
Orphan Drug 2016 NHLBI 5F30HL122096-03 Clonal Evolution and Prospective Isolation of Myelodysplastic Syndrome Initiating CHEN, JAMES STANFORD UNIVERSITY CA $36,197
Orphan Drug 2016 NIAID 5UM1AI069453-10 KARABELO Clinical Trials Unit for NIAID Networks GRAY, GLENDA WITS HEALTH CONSORTIUM (PTY), LTD SO AFR $918,589
Orphan Drug 2016 NIAID 4R01AI047194-14 Pharmacological Diversity of nAChRs in Clade III Nematodes: Levamisole receptors MARTIN, RICHARD IOWA STATE UNIVERSITY IA $359,054
Orphan Drug 2016 NCI 5R21CA175699-02 Pancreatic cancer control by a novel combination treatment MACKENZIE, GERARDO STATE UNIVERSITY NEW YORK STONY BROOK NY $171,825
Orphan Drug 2016 NCI 5R03CA184394-02 Intraperitoneal Delivery of Targeted Nanoparticles for Metastatic Ovarian Cancer LU, XIULING UNIVERSITY OF CONNECTICUT STORRS CT $79,000
Orphan Drug 2016 NIAID 4UM1AI069536-10 HIV CENTERS FOR UNDEREPRESENTED POPULATIONS IN RESEARCH CTU (HIV CURE CTU) SPECTOR, STEPHEN UNIVERSITY OF CALIFORNIA SAN DIEGO CA $2,074,220
Orphan Drug 2016 NIGMS 4R01GM097327-04 Examining the role of Cbk1/NDR kinase in regulating mRNA localization LUCA, FRANCIS UNIVERSITY OF PENNSYLVANIA PA $312,000
Orphan Drug 2016 NICHD 4R01HD062484-06 Pharmacogenetic Determinants of Vincristine Toxicity and Response RENBARGER, JAMIE INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS IN $614,577
Orphan Drug 2016 NCI 5P30CA014195-43 7749 PL Mouse HUNTER, TONY SALK INSTITUTE FOR BIOLOGICAL STUDIES CA $24,972
Orphan Drug 2016 NCI 5R01CA175380-03 FoxM1 in liver cancer. RAYCHAUDHURI, PRADIP UNIVERSITY OF ILLINOIS AT CHICAGO IL $405,146
Orphan Drug 2016 NCI 5F30CA183530-03 Characterizing the genomic architecture and molecular mechanisms driving the form CLARK, VICTORIA YALE UNIVERSITY CT $44,225
Orphan Drug 2016 NICHD 5R01HD082127-02 Behavioral Inflexibility in IDD Outcome Measurement BOYD, BRIAN UNIV OF NORTH CAROLINA CHAPEL HILL NC $597,893
Orphan Drug 2016 NHLBI 4R01HL117654-04 Hyperhomocysteinemia and HDL Metabolism WANG, HONG TEMPLE UNIV OF THE COMMONWEALTH PA $620,768
Orphan Drug 2016 NCI 4R01CA097061-13 Chemical genetic profiling of engineered tumor cells STOCKWELL, BRENT COLUMBIA UNIV NEW YORK MORNINGSIDE NY $350,176
Orphan Drug 2016 NCI 4R01CA173077-04 In vivo imaging of encapsulated stem cells in mouse models of tumor resection SHAH, KHALID MASSACHUSETTS GENERAL HOSPITAL MA $358,622
Orphan Drug 2016 NCI 4R01CA172380-04 Determining the Roles of ATRX and DAXX Abnormalities in Cancer Telomere Biology MEEKER, ALAN JOHNS HOPKINS UNIVERSITY MD $335,820
Orphan Drug 2016 NCI 5R21CA191896-02 Influence of germ line genetic variation on myeloma progression and survival ZIV, ELAD UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $176,240
Orphan Drug 2016 NCI 5R21CA191929-02 Establish RPN 13-Proteasome Association as a Novel Anticancer Target HILL, CHRISTOPHER UNIVERSITY OF UTAH UT $162,038
Orphan Drug 2016 NCI 5R01CA181658-02 MRI-Monitored Delivery of Sorafenib-Eluting Microspheres to Liver Tumors LARSON, ANDREW NORTHWESTERN UNIVERSITY AT CHICAGO IL $441,814
Orphan Drug 2016 NCI 5R01CA190617-02 Itraconazole Analogues to Treat Medulloblastoma HADDEN, MATTHEW UNIVERSITY OF CONNECTICUT STORRS CT $367,973
Orphan Drug 2016 NCI 5P30CA008748-50 7554 Animal Imaging LEKAYE, CARL SLOAN-KETTERING INST CAN RESEARCH NY $247,784
Orphan Drug 2016 NCI 5P30CA008748-50 7572 Research Pharmacy MULLER, RAYMOND SLOAN-KETTERING INST CAN RESEARCH NY $206,350
Orphan Drug 2016 NIAID 5R44AI100339-04 Novel Plasmodial Surface Anion Channel Inhibitors as Antimalarial Drugs BUTLER, MICHELLE MICROBIOTIX, INC MA $689,746
Orphan Drug 2016 NIAID 5R44AI100401-04 Broad Spectrum Antiviral Nucleoside Phosphonate Analogs LIPKA, ELKE TSRL, INC. MI $990,162
Orphan Drug 2016 NCI 5P30CA016042-41 6733 Tumor Immunology GASSON, JUDITH UNIVERSITY OF CALIFORNIA LOS ANGELES CA $28,121
Orphan Drug 2016 NCI 5P30CA016042-41 6743 Early Phase Clinical Research Support GASSON, JUDITH UNIVERSITY OF CALIFORNIA LOS ANGELES CA $94,438
Orphan Drug 2016 NCI 5R01CA175772-03 Targeting tumor-stromal interaction for pancreatic cancer therapy SINGH, AJAY UNIVERSITY OF SOUTH ALABAMA AL $314,363
Orphan Drug 2016 NCI 5R01CA189986-02 KSHV alteration of cellular metabolism LAGUNOFF, MICHAEL UNIVERSITY OF WASHINGTON WA $344,268
Orphan Drug 2016 NCI 5R01CA191077-02 Assay Development for NSD1 Methyltransferase Inhibitor Discovery NAPPER, ANDREW ALFRED I. DU PONT HOSP FOR CHILDREN DE $312,244
Orphan Drug 2016 NIAID 4R37AI042767-18 Regulation of primary and secondary CD4 and CD8 T cell memory HARTY, JOHN UNIVERSITY OF IOWA IA $562,607
Orphan Drug 2016 NCI 5R01CA172070-04 Rab Geranylgeranylation: a Novel Therapeutic Target in Multiple Myeloma HOLSTEIN, SARAH ROSWELL PARK CANCER INSTITUTE CORP NY $216,584
Orphan Drug 2016 NIDDK 4R01DK052962-13 Novel Globin Gene Modulators PERRINE, SUSAN BOSTON UNIVERSITY MEDICAL CAMPUS MA $356,048
Orphan Drug 2016 NIGMS 5R01GM107465-02 Molecular principles of translation termination KOROSTELEV, ANDREI UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $322,438
Orphan Drug 2016 NHLBI 5F31HL126484-02 Deciphering the mechanisms of how the RAF/MEK/ERK pathway controls dendritic cell HOGSTAD, BRANDON ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI NY $38,021
Orphan Drug 2016 NCI 5R01CA055349-22 Mechanisms of action of a TCR-like antibody to WT1 SCHEINBERG, DAVID SLOAN-KETTERING INST CAN RESEARCH NY $384,667
Orphan Drug 2016 NCI 5R03CA191621-02 Developing a Screen for Novel Therapies with Reprogrammed Pancreatic Cancer Cells RESAR, LINDA JOHNS HOPKINS UNIVERSITY MD $81,000
Orphan Drug 2016 NEI 5R01EY013433-09 A Ribozyme Rescue Strategy for Autosomal Dominant Retinitis Pigmentosa SULLIVAN, JOHN STATE UNIVERSITY OF NEW YORK AT BUFFALO NY $378,000
Orphan Drug 2016 NHLBI 5R01HL118312-03 Nanotechnology Approach for Inhalation Treatment of Pulmonary Fibrosis MINKO, TAMARA RUTGERS, THE STATE UNIV OF N.J. NJ $470,334
Orphan Drug 2016 NCI 5R21CA191898-02 Novel therapeutic strategies targeting conformational plasticity of type I MAGE CHO, HEARN ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI NY $182,588
Orphan Drug 2016 NINDS 4R01NS040433-14 Immune Regulation of Neuronal Injury and Repair JONES, KATHRYN INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS IN $463,254
Orphan Drug 2016 NCI 5F32CA189633-02 Targeted Delivery of Theranostic Nanoparticles Carrying Immune Modulators BOZEMAN, ERICA EMORY UNIVERSITY GA $56,118
Orphan Drug 2016 NCI 4R01CA165206-05 CD19 Directed CAR Therapy JUNE, CARL UNIVERSITY OF PENNSYLVANIA PA $237,659
Orphan Drug 2016 NIAID 5U01AI112367-02 Safety and efficacy of PfSPZ malaria vaccine in malaria-exposed adults PLOWE, CHRISTOPHER UNIVERSITY OF MARYLAND BALTIMORE MD $626,608
Orphan Drug 2016 NIGMS 4R01GM098956-06 Ras18-mediated Fanconi Anemia pathway activation in response to camptothecin PALLE, KOMARAIAH UNIVERSITY OF SOUTH ALABAMA AL $228,690
Orphan Drug 2016 NHLBI 5R01HL118068-03 Endothelial Regeneration Following Lung Vascular Injury MALIK, ASRAR UNIVERSITY OF ILLINOIS AT CHICAGO IL $579,810
Orphan Drug 2016 NHLBI 4P01HL112761-04 7685 FIX GENE THERAPY AND ROLE OF AAV NAb SAMULSKI, RICHARD UNIV OF NORTH CAROLINA CHAPEL HILL NC $173,450
Orphan Drug 2016 NHLBI 4P01HL112761-04 7686 HUMANIZING AAV VECTORS FOR GENE THERAPY ASOKAN, ARAVIND UNIV OF NORTH CAROLINA CHAPEL HILL NC $167,202
Orphan Drug 2016 NHLBI 4P01HL112761-04 7687 INTRAARTICULAR AAV TO CIRCUMVENT SYSTEMIC NEUTRALIZATION MONAHAN, PAUL UNIV OF NORTH CAROLINA CHAPEL HILL NC $152,001
Orphan Drug 2016 NHLBI 4P01HL112761-04 7688 GENERATION OF A MODEL OF HEMOPHILIA B IN AAV RESISTANT PRIMATES SULLENGER, BRUCE UNIV OF NORTH CAROLINA CHAPEL HILL NC $188,279
Orphan Drug 2016 NHLBI 4P01HL112761-04 7691 ANIMAL MODELS CORE LI, CHENGWEN UNIV OF NORTH CAROLINA CHAPEL HILL NC $264,245
Orphan Drug 2016 NHLBI 4P01HL112761-04 5691 FIX GENE THERAPY AND ROLE OF AAV NAb SAMULSKI, RICHARD UNIV OF NORTH CAROLINA CHAPEL HILL NC $173,448
Orphan Drug 2016 NHLBI 4P01HL112761-04 5692 HUMANIZING AAV VECTORS FOR GENE THERAPY ASOKAN, ARAVIND UNIV OF NORTH CAROLINA CHAPEL HILL NC $167,200
Orphan Drug 2016 NHLBI 4P01HL112761-04 5693 INTRAARTICULAR AAV TO CIRCUMVENT SYSTEMIC NEUTRALIZATION MONAHAN, PAUL UNIV OF NORTH CAROLINA CHAPEL HILL NC $151,999
Orphan Drug 2016 NHLBI 4P01HL112761-04 5694 GENERATION OF A MODEL OF HEMOPHILIA B IN AAV RESISTANT PRIMATES SULLENGER, BRUCE UNIV OF NORTH CAROLINA CHAPEL HILL NC $188,279
Orphan Drug 2016 NHLBI 4P01HL112761-04 5697 ANIMAL MODELS CORE SUN, JUNJIANG UNIV OF NORTH CAROLINA CHAPEL HILL NC $264,244
Orphan Drug 2016 NIAID 5F32AI110028-03 The POA-RpsA interaction in trans-translation inhibition in M. tuberculosis GUERRA LARA, ALFREDO JOHNS HOPKINS UNIVERSITY MD $58,002
Orphan Drug 2016 NIAID 4R01AI069227-10 Surface Proteins of Bacillus anthracis SCHNEEWIND, OLAF UNIVERSITY OF CHICAGO IL $384,624
Orphan Drug 2016 NCI 4R01CA168448-04 Next Generation Oncolytic Adenovirus for Advanced Pancreatic Cancer Treatment YAMAMOTO, MASATO UNIVERSITY OF MINNESOTA MN $315,400
Orphan Drug 2016 NCI 4R01CA172582-04 Alpha Radioimmunotherapy for Lymphoma Treatment SANDMAIER, BRENDA FRED HUTCHINSON CANCER RESEARCH CENTER WA $634,846
Orphan Drug 2016 NCI 5K08CA181340-03 Targeting Chromatin Modifications in Leukemia with Trisomy 21 LANE, ANDREW DANA-FARBER CANCER INST MA $155,991
Orphan Drug 2016 NCI 5R01CA183444-03 Molecular Evaluation of Targeted Therapies in Lymphoid Malignancies BYRD, JOHN OHIO STATE UNIVERSITY OH $536,570
Orphan Drug 2016 NIBIB 5R01EB019458-02 Pre-clinical quantitation of ovarian cancer tumor burden using Magnetic Particle Imaging and non-dilutive cell labeling CONOLLY, STEVEN UNIVERSITY OF CALIFORNIA BERKELEY CA $483,566
Orphan Drug 2016 NCI 4R01CA167511-04 Translation of Novel Therapeutic Targets in Multiple Myeloma STEWART, ALEXANDER MAYO CLINIC ARIZONA AZ $431,907
Orphan Drug 2016 NIAID 5R01AI104817-04 HOST AND MICROBIOLOGICAL DETERMINANTS OF INFECTIOUSNESS IN PATIENTS WITH DRUG SEN DHEDA, KEERTAN UNIVERSITY OF CAPE TOWN SO AFR $132,907
Orphan Drug 2016 NIAID 5R44AI115759-02 Development of Small Molecule Therapeutics Against Smallpox and Other Poxviruses SCOTT, RICHARD FOX CHASE CHEMICAL DIVERSITY CENTER, INC PA $1,197,020
Orphan Drug 2016 NIAID 5R01AI110478-03 Innovative partnership to target antimalarial subsidies in the retail sector PRUDHOMME O'MEARA, WENDY DUKE UNIVERSITY NC $539,740
Orphan Drug 2016 NIAID 5R21AI111025-02 Type II-NDHs in M. tuberculosis respiration and persistence ZAHRT, THOMAS MEDICAL COLLEGE OF WISCONSIN WI $229,500
Orphan Drug 2016 NCI 5R21CA191594-02 Internet-Assisted Cognitive Behavior Intervention for Targeted Therapy Fatigue JIM, HEATHER H. LEE MOFFITT CANCER CTR & RES INST FL $188,437
Orphan Drug 2016 NCI 4F32CA177094-03 Peptide-mediated delivery of siRNA for treatment of ovarian cancer KWON, ESTER MASSACHUSETTS INSTITUTE OF TECHNOLOGY MA $26,575
Orphan Drug 2016 NIAID 5R21AI112328-02 Nucleoside-Nucleobase Transporters in the Biology and Pathogenesis of T. cruzi ULLMAN, BUDDY OREGON HEALTH & SCIENCE UNIVERSITY OR $231,000
Orphan Drug 2016 NICHD 5UG1HD083166-02 Collaborative Research to Validate Biomarkers of Pediatric ARDS MCQUILLEN, PATRICK UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $272,476
Orphan Drug 2016 NIAAA 5P50AA011999-18 8467 Functional Dissection of EtOH-med Self-renew of Liver Tumor-Int Cells via TLR4 MACHIDA, KEIGO UNIVERSITY OF SOUTHERN CALIFORNIA CA $203,571
Orphan Drug 2016 NCI 5R21CA179362-02 A Creative Integration of Omega-3 Fatty Acids into Pancreatic Cancer Chemotherapy CUI, ZHENGRONG UNIVERSITY OF TEXAS, AUSTIN TX $202,928
Orphan Drug 2016 NCI 5R01CA184088-02 Liposomal Doxorubicin and Pluronic Combination for Cancer Therapy KABANOV, ALEXANDER UNIV OF NORTH CAROLINA CHAPEL HILL NC $344,549
Orphan Drug 2016 NCI 5R21CA185036-02 Identification and Targeting Therapy Resistant Osteosarcoma MAKI, CARL RUSH UNIVERSITY MEDICAL CENTER IL $167,987
Orphan Drug 2016 NCI 5R21CA191631-02 Dual recombinase models of pancreatic cancer SEELEY, ELLIOTT UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $172,369
Orphan Drug 2016 NCI 5R01CA174861-03 Novel Theranostics for Pancreatic Cancer DAVYDOVA, JULIA UNIVERSITY OF MINNESOTA MN $319,031
Orphan Drug 2016 NCI 5R01CA172724-02 Novel Strategies to Target Leukemia-Stromal Interactions HUANG, PENG UNIVERSITY OF TX MD ANDERSON CAN CTR TX $366,000
Orphan Drug 2016 NCI 5R21CA191515-02 New transgenic animal model to study pancreatic cancer FISHER, PAUL VIRGINIA COMMONWEALTH UNIVERSITY VA $178,234
Orphan Drug 2016 NIAID 4R01AI104702-04 Antigen exposure in utero: impacts on newborn immunity and infectious diseases CAIRO, CRISTIANA UNIVERSITY OF MARYLAND BALTIMORE MD $372,562
Orphan Drug 2016 NIAID 5R21AI115993-02 Drug permeation and activity in Mycobacterium tuberculosis infected macrophages WARNER, DIGBY UNIVERSITY OF CAPE TOWN SO AFR $30,749
Orphan Drug 2016 NIAID 5R03AI113619-02 BLOCKING HSV INFECTION WITH BORTEZOMIB NICOLA, ANTHONY WASHINGTON STATE UNIVERSITY WA $75,500
Orphan Drug 2016 NCI 5R01CA120813-10 Modulation of Microglia and T Cell Interactions in Malignant Glioma HEIMBERGER, AMY UNIVERSITY OF TX MD ANDERSON CAN CTR TX $288,000
Orphan Drug 2016 NIAID 4R01AI097494-04 The Impact of Diabetes on TB treatment outcomes GOLUB, JONATHAN JOHNS HOPKINS UNIVERSITY MD $588,329
Orphan Drug 2016 NIGMS 5R01GM113236-02 Exosomes and HB-EGF in Stem Cell-Mediated Therapy for Necrotizing Enterocolitis BESNER, GAIL RESEARCH INST NATIONWIDE CHILDREN'S HOSP OH $393,263
Orphan Drug 2016 NIAID 4R01AI105204-04 Preclinical characterization of a multivalent killed Filovirus/Rabies vaccine SCHNELL, MATTHIAS THOMAS JEFFERSON UNIVERSITY PA $1,090,934
Orphan Drug 2016 NIAID 4R01AI105172-04 Conjugate Anthrax Vaccine with Dual Virulence Factor Specificity GIRI, LALLAN BIOLOGICS RESOURCES, LLC MD $1,077,395
Orphan Drug 2016 NIAID 4R01AI105422-04 An adjuvant that promotes TH1/TH17 and CD8 T cells in a tuberculosis vaccine FLYNN, JOANNE UNIVERSITY OF PITTSBURGH AT PITTSBURGH PA $1,124,887
Orphan Drug 2016 NCI 5R01CA190635-02 Genetic Framework and Molecular Mechanism of Fanconi Anemia LI, LEI UNIVERSITY OF TX MD ANDERSON CAN CTR TX $366,000
Orphan Drug 2016 NIAID 5R44AI069631-07 Genetically Attenuated PfSPZ Malaria Vaccine HOFFMAN, STEPHEN SANARIA, INC. MD $999,996
Orphan Drug 2016 NIAID 5R44AI085740-04 In-Vitro Culture of Plasmodium falciparum Sporozoites for Malaria Vaccine HOFFMAN, STEPHEN SANARIA, INC. MD $999,997
Orphan Drug 2016 NIAID 5R21AI117158-02 Empirically Defining Gene Architecture and Expression of M. Tuberculosis DERBYSHIRE, KEITH WADSWORTH CENTER NY $207,135
Orphan Drug 2016 NCI 5R01CA190498-02 gp130 as a novel therapeutic target in ovarian cancer NEAMATI, NOURI UNIVERSITY OF MICHIGAN MI $376,320
Orphan Drug 2016 NINDS 5R01NS083813-03 Molecular Mechanisms Controlling Wallerian Degeneration of Axons TESSIER-LAVIGNE, MARC ROCKEFELLER UNIVERSITY NY $370,781
Orphan Drug 2016 NIAID 1R34AI120917-01 A Phase I/II Trial of the Safety, Tolerability and Immunogenicity of a Live Attenuated Tetravalent Dengue Virus Vaccine in Adults in Dengue-Endemic Bangladesh KIRKPATRICK, BETH UNIVERSITY OF VERMONT & ST AGRIC COLLEGE VT $233,979
Orphan Drug 2016 NIDDK 5R01DK100595-03 Regulation of Globin Gene Switching by O-GlcNAc Post-Translational Modification PETERSON, KENNETH UNIVERSITY OF KANSAS MEDICAL CENTER KS $262,740
Orphan Drug 2016 NIAID 5UM1AI069476-09 The FIOCRUZ Therapeutic and Prevention HIV/AIDS Clinical Trials Unit GRINSZTEJN, BEATRIZ FUNDACAO OSWALDO CRUZ BRAZIL $1,104,340
Orphan Drug 2016 NIAID 5U19AI109680-03 7495 Identification and Development of Anti-Flavivirus Lead Drug Candidates NELSON, JAY OREGON HEALTH & SCIENCE UNIVERSITY OR $838,269
Orphan Drug 2016 NIAID 5U19AI109680-03 7497 Novel Therapeutic Strategies Targeting Re-emerging Alphaviruses STREBLOW, DANIEL OREGON HEALTH & SCIENCE UNIVERSITY OR $993,983
Orphan Drug 2016 NIAID 5U19AI109680-03 7500 Screening Core BOSTWICK, JAMES SOUTHERN RESEARCH INSTITUTE AL $1,453,428
Orphan Drug 2016 NIAID 5R21AI117131-02 The Pseudomonas aeruginosa protease CtpA and type 3 secretion DARWIN, ANDREW NEW YORK UNIVERSITY SCHOOL OF MEDICINE NY $211,875
Orphan Drug 2016 NIDDK 5R01DK048252-22 Transgene Persistence in Liver Gene Therapy GROMPE, MARKUS OREGON HEALTH & SCIENCE UNIVERSITY OR $368,829
Orphan Drug 2016 NINDS 5R21NS091637-02 Identification of New Human Targets to Inhibit Decay of PTC-containing mRNAs ALEXANDROV, ANDREI YALE UNIVERSITY CT $166,500
Orphan Drug 2016 NIAID 5U19AI111224-02 7574 Animal Models Core RAYCHAUDHURI, SOUMYA BRIGHAM AND WOMEN'S HOSPITAL MA $343,023
Orphan Drug 2016 NIAID 5R21AI117162-02 Targeting an immunomodulatory protease for adjunctive tuberculosis chemotherapy RENGARAJAN, JYOTHI EMORY UNIVERSITY GA $227,647
Orphan Drug 2016 NCI 5R21CA186004-02 Immunotherapeutic targeting of the Glioblastoma Mutanome PRINS, ROBERT UNIVERSITY OF CALIFORNIA LOS ANGELES CA $200,100
Orphan Drug 2016 NIDCD 4R01DC012596-04 Correction of Hearing and Vestibular Defects in a Mouse Model for Deafness HASTINGS, MICHELLE ROSALIND FRANKLIN UNIV OF MEDICINE & SCI IL $319,388
Orphan Drug 2016 NIDDK 4R01DK084033-07 AAV Gene Therapy for AAT Deficiency SAMULSKI, RICHARD UNIV OF NORTH CAROLINA CHAPEL HILL NC $319,241
Orphan Drug 2016 NIGMS 5SC3GM112543-02 Aberrant Epigenetic Repression in Esophageal Malignancy LIN, CHIN-HSING ANNIE UNIVERSITY OF TEXAS SAN ANTONIO TX $105,691
Orphan Drug 2016 NINDS 5R21NS088786-02 Biomarker discovery for juvenile neuronal ceroid lipofuscinosis SLEAT, DAVID RBHS-ROBERT WOOD JOHNSON MEDICAL SCHOOL NJ $238,500
Orphan Drug 2016 NCI 5R01CA181449-02 Interrogation of MLL2 as a tumor suppressor gene in lung cancer MACPHERSON, DAVID FRED HUTCHINSON CANCER RESEARCH CENTER WA $402,600
Orphan Drug 2016 NHLBI 5R01HL121264-03 Endothelialized microfluidics for sickle cell disease research & drug discovery LAM, WILBUR EMORY UNIVERSITY GA $390,164
Orphan Drug 2016 NINDS 5R21NS091654-02 Development of Molecular Therapy for Carbamoyl Phosphate Synthetase Deficiency LIPSHUTZ, GERALD UNIVERSITY OF CALIFORNIA LOS ANGELES CA $231,000
Orphan Drug 2016 NEI 5R01EY002422-35 Mechanisms and Therapeutic Treatments for Inherited Retinal Degenerative Diseases MOLDAY, ROBERT UNIVERSITY OF BRITISH COLUMBIA CANADA $267,961
Orphan Drug 2016 NINDS 5R01NS088059-02 HTS to identify small molecules to disrupt abnormal huntingtin interactions in HD MUMA, NANCY UNIVERSITY OF KANSAS LAWRENCE KS $512,946
Orphan Drug 2016 NCI 1P50CA192937-01A1 7608 BIOSTATISTICS AND BIOINFORMATICS CORE SESHAN, VENKATRAMAN SLOAN-KETTERING INST CAN RESEARCH NY $182,764
Orphan Drug 2016 NCI 1P50CA192937-01A1 7611 Development of Mechanism-Based Therapy For Myc+/Bcl2+ Diffuse Large B Cell Lymphoma YOUNES, ANAS SLOAN-KETTERING INST CAN RESEARCH NY $275,717
Orphan Drug 2016 NCI 1P50CA192937-01A1 7613 Translating Stress Response Targeted Therapy for B-Cell Lymphomas CHIOSIS, GABRIELA SLOAN-KETTERING INST CAN RESEARCH NY $317,872
Orphan Drug 2016 NCI 1P50CA192937-01A1 7614 Targeting Acetyltransferase Gene Inactivation in Diffuse Large B Cell Lymphoma ZELENETZ, ANDREW SLOAN-KETTERING INST CAN RESEARCH NY $381,366
Orphan Drug 2016 NCI 4R01CA165469-04 Role of Tcl1 and Par-4 in regulation of chronic lymphocytic leukemia BONDADA, SUBBARAO UNIVERSITY OF KENTUCKY KY $381,420
Orphan Drug 2016 NIAID 5R01AI051334-13 Extracellular Matix Adhesins of Treponema pallidum CAMERON, CAROLINE UNIVERSITY OF VICTORIA CANADA $236,542
Orphan Drug 2016 NIAID 5U01AI115619-02 Biology and Biosignatures of Anti-Tuberculosis Treatment Response BELISLE, JOHN COLORADO STATE UNIVERSITY CO $619,889
Orphan Drug 2016 NCI 4R01CA163462-05 MUC1 Roles in ovarian cancer pathogenesis and immune therapy VLAD, ANDA MAGEE-WOMEN'S RES INST AND FOUNDATION PA $287,489
Orphan Drug 2016 NCI 5R01CA186043-02 Musashi-mediated control of pancreatic cancer growth and progression REYA, TANNISHTHA UNIVERSITY OF CALIFORNIA SAN DIEGO CA $379,518
Orphan Drug 2016 NHLBI 5R01HL108962-06 Gene-by-Gene Interactions and Lung Fluid Balance in Patients with Heart Failure SNYDER, ERIC UNIVERSITY OF MINNESOTA MN $380,049
Orphan Drug 2016 NINDS 5R01NS053677-11 Mechanisms of Substrate Reduction Therapy for Niemann-Pick C Disease DOBRENIS, KOSTANTIN ALBERT EINSTEIN COLLEGE OF MEDICINE, INC NY $350,656
Orphan Drug 2016 NINDS 5R03NS087979-02 Mouse Pneumotropic Virus Infection: A Model for JC Virus Latency and Reactivation FUJINAMI, ROBERT UNIVERSITY OF UTAH UT $74,500
Orphan Drug 2016 NIAID 5R41AI118122-02 Novel filovirus entry inhibitors based on a pseudo-symmetrical biphenyl core RONG, LIJUN MICROBIOTIX, INC MA $288,106
Orphan Drug 2016 NHLBI 4R01HL111969-05 Biomarkers of Inflammation and Vaso-occlusion in Sickle Cell Disease LINDEN, JOEL LA JOLLA INST FOR ALLERGY & IMMUNOLGY CA $799,323
Orphan Drug 2016 NHLBI 4R01HL114770-04 Functional consequences of FHC mutations in cardiac MyBPC STELZER, JULIAN CASE WESTERN RESERVE UNIVERSITY OH $396,250
Orphan Drug 2016 NCI 2P30CA016520-40 8007 Hematologic Malignancies Research Program STADTMAUER, EDWARD UNIVERSITY OF PENNSYLVANIA PA $72,887
Orphan Drug 2016 NCI 2P30CA016520-40 8009 Pediatric Oncology Research Program BRODEUR, GARRETT UNIVERSITY OF PENNSYLVANIA PA $70,898
Orphan Drug 2016 NIAID 5R01AI116723-02 Optimization of Antischistosomal Chemotypes VENNERSTROM, JONATHAN UNIVERSITY OF NEBRASKA MEDICAL CENTER NE $598,659
Orphan Drug 2016 NCI 5R01CA193244-06 Role of microR-122 in Hepatocarcinogenesis using Conditional Knockout Mice GHOSHAL, KALPANA OHIO STATE UNIVERSITY OH $368,367
Orphan Drug 2016 NEI 5R44EY019811-03 Vision Restoration with Photoswitch Technology TRAUTMAN, JAY PHOTOSWITCH BIOSCIENCES, INC. CA $488,070
Orphan Drug 2016 NHLBI 4R01HL113006-05 Human Induced Pluripotent Stem Cells for Cardiovascular Disease Modeling WU, JOSEPH STANFORD UNIVERSITY CA $393,018
Orphan Drug 2016 NHLBI 4K23HL116656-04 Lung Transplant donor: prediction, evaluation, and mechanism CANTU, EDWARD UNIVERSITY OF PENNSYLVANIA PA $195,732
Orphan Drug 2016 NINDS 5R01NS083795-03 Using Cell-Penetrant Peptides to Target ATF5 in Mouse Glioma Models ANGELASTRO, JAMES UNIVERSITY OF CALIFORNIA AT DAVIS CA $325,389
Orphan Drug 2016 NCI 2P30CA014089-41 8288 Molecular Genetics Research Program (Project-001) LIEBER, MICHAEL UNIVERSITY OF SOUTHERN CALIFORNIA CA $35,512
Orphan Drug 2016 NCI 2P30CA014089-41 8293 Gastrointestinal Cancers Research Program (Project-006) KAHN, MICHAEL UNIVERSITY OF SOUTHERN CALIFORNIA CA $35,512
Orphan Drug 2016 NIA 2P01AG017586-16 8502 Project 2: Genetic Modifiers of Tauopathies SCHELLENBERG, GERARD UNIVERSITY OF PENNSYLVANIA PA $352,291
Orphan Drug 2016 NCI 2P30CA016086-40 8610 Animal Models WEISSMAN, BERNARD UNIV OF NORTH CAROLINA CHAPEL HILL NC $308,421
Orphan Drug 2016 NCI 2P30CA016086-40 8627 EARLY PHASE CLINICAL RESEARCH SUPPORT (Core 020) DEES, ELIZABETH UNIV OF NORTH CAROLINA CHAPEL HILL NC $283,606
Orphan Drug 2016 NCI 2P30CA016086-40 8629 Immunology Research Program (Program 2) SERODY, JONATHAN UNIV OF NORTH CAROLINA CHAPEL HILL NC $38,923
Orphan Drug 2016 NCI 2P30CA016086-40 8631 Virology Research Program (Program 4) RAAB-TRAUB, NANCY UNIV OF NORTH CAROLINA CHAPEL HILL NC $45,983
Orphan Drug 2016 NIAID 5R01AI116665-03 Inhibitors of Purine Import into Plasmodium falciparum Kill Malaria Parasites AKABAS, MYLES ALBERT EINSTEIN COLLEGE OF MEDICINE, INC NY $682,631
Orphan Drug 2016 NCI 5R01CA184354-03 MRI fluorescence tomography for quantifying tumor receptor concentration in vivo DAVIS, SCOTT DARTMOUTH COLLEGE NH $492,912
Orphan Drug 2016 NIAAA 5R01AA021978-03 Role of ECM and inflammatory remodeling in alcohol-induced liver and lung damage ARTEEL, GAVIN UNIVERSITY OF LOUISVILLE KY $387,569
Orphan Drug 2016 NIAID 5U19AI109664-03 6975 SMALL MOLECULE INHIBITORS OF FILOVIRAL INTERFERON ANTAGONISTS: ASSAY DEVELOPMENT BASLER, CHRISTOPHER ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI NY $822,509
Orphan Drug 2016 NIAID 5U19AI109664-03 6976 SMALL MOLECULE SCREENING TO IDENTIFY INHIBITORS OF FILOVIRAL BASU, ARNAB ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI NY $1,064,841
Orphan Drug 2016 NIAID 5U19AI109664-03 6977 SMALL MOLECULES DISABLING DEPHOSPHORYLATION OF EBOLA AND BUKREYEV, ALEXANDER ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI NY $578,657
Orphan Drug 2016 NIAID 5U19AI109664-03 6978 ADMINISTRATIVE CORE BASLER, CHRISTOPHER ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI NY $201,952
Orphan Drug 2016 NIAID 5U19AI109664-03 6979 BIOSAFETY LEVEL 4 CORE BUKREYEV, ALEXANDER ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI NY $454,545
Orphan Drug 2016 NCI 5U01CA176110-03 Quantitative (Perfusion and Diffusion) MRI Biomarkers to Measure Glioma Response SCHMAINDA, KATHLEEN MEDICAL COLLEGE OF WISCONSIN WI $426,449
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