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RCDC

Project Listing by Category


Back to Estimates of Funding for Various Research, Condition, and Disease Categories (RCDC) Click the column headings to sort project listings.
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CategoryFYFunding ICProject NumberSub Project #Project TitlePI NameOrg NameState / CountryAmount
Huntington's Disease 2016 NINDS 5F31NS090859-02 Modeling the neurovascular unit using Huntington's disease iPS cells LIM, RYAN UNIVERSITY OF CALIFORNIA-IRVINE CA $43,576
Huntington's Disease 2016 NINDS 4R01NS036232-17 Neuronal function of huntingtin associated protein LI, XIAO-JIANG EMORY UNIVERSITY GA $335,453
Huntington's Disease 2016 NIGMS 5R01GM112678-02 Structural polymorphism in the misfolding and aggregation of expanded polyglutamine proteins VAN DER WEL, PATRICK UNIVERSITY OF PITTSBURGH AT PITTSBURGH PA $280,529
Huntington's Disease 2016 NINDS 4R01NS039074-13 Mechanisms of Huntingtin-induced Neurodegeneration FINKBEINER, STEVEN J. DAVID GLADSTONE INSTITUTES CA $376,031
Huntington's Disease 2016 NIGMS 4R01GM073042-12 Allele-Selective Inhibitors for Expanded Trinucleotide Repeat Genes COREY, DAVID UT SOUTHWESTERN MEDICAL CENTER TX $325,553
Huntington's Disease 2016 NINDS 5R01NS089076-02 Epigenetic pathology and therapy in Huntington's disease FRAENKEL, ERNEST MASSACHUSETTS INSTITUTE OF TECHNOLOGY MA $554,354
Huntington's Disease 2016 NINDS 5R01NS088059-02 HTS to identify small molecules to disrupt abnormal huntingtin interactions in HD MUMA, NANCY UNIVERSITY OF KANSAS LAWRENCE KS $512,946
Huntington's Disease 2016 NIGMS 1SC2GM116697-01 Cellular mechanisms underlying detoxification of mutant Huntingtin EMTAGE, LESLEY YORK COLLEGE NY $152,453
Huntington's Disease 2016 NINDS 5R01NS090914-02 Modeling the effects of reducing huntingtin and Hdh alternative splicing in mice ZEITLIN, SCOTT UNIVERSITY OF VIRGINIA VA $345,625
Huntington's Disease 2016 NINDS 1R01NS094577-01 Rhes-SUMO circuitry in Huntington's Disease Pathogenesis SUBRAMANIAM, SRINIVASA SCRIPPS FLORIDA FL $420,000
Huntington's Disease 2016 NINDS 5R01NS040408-14 Signaling Pathways Regulating Neuronal Survival D'MELLO, SANTOSH SOUTHERN METHODIST UNIVERSITY TX $320,469
Huntington's Disease 2016 NINDS 4R01NS055193-08 Mitochondrial fission in Huntington's Disease BOSSY-WETZEL, ELLA UNIVERSITY OF CENTRAL FLORIDA FL $313,790
Huntington's Disease 2016 NINDS 5R01NS086452-03 Validation of Novel Pathogenic Htt Post-Translational Modifications (PTMs) ROSS, CHRISTOPHER JOHNS HOPKINS UNIVERSITY MD $626,506
Huntington's Disease 2016 NINDS 5F31NS092281-02 HPA-axis dysfunction in Huntington's disease DUFOUR, BRETT OREGON HEALTH & SCIENCE UNIVERSITY OR $43,576
Huntington's Disease 2016 NINDS 5R01NS086746-02 NAD, PGC-1alpha and SIRT3 as Therapeutics Targets for Huntington's Disease BEAL, M WEILL MEDICAL COLL OF CORNELL UNIV NY $370,781
Huntington's Disease 2016 NINDS 5R03NS092024-02 A synthetic vesicle to carry modifier compounds to axonal blocks induced by pathogenic polyQ GUNAWARDENA, SHERMALI STATE UNIVERSITY OF NEW YORK AT BUFFALO NY $77,797
Huntington's Disease 2016 NIEHS 5R01ES016931-08 Gene-Neurotoxicant Interactions in Huntington Disease BOWMAN, AARON VANDERBILT UNIVERSITY TN $32,913
Huntington's Disease 2016 OD 5R24OD010930-11 Transgenic Huntington's disease monkey resource CHAN, ANTHONY WING SANG EMORY UNIVERSITY GA $848,211
Huntington's Disease 2016 NIGMS 5R01GM114665-02 Novel Aspects of Golf Signaling ROBISHAW, JANET GEISINGER CLINIC PA $363,000
Huntington's Disease 2016 NIMH 5R01MH018501-47 Neurochemical Actions of Psychotropic Drugs SNYDER, SOLOMON JOHNS HOPKINS UNIVERSITY MD $865,725
Huntington's Disease 2016 NINDS 5R01NS084345-02 Molecular mechanisms of huntingtin misfolding LANGEN, RALF UNIVERSITY OF SOUTHERN CALIFORNIA CA $469,358
Huntington's Disease 2016 NINDS 5R01NS092578-02 Investigating CD47-SIRPa as novel protective signals during CNS synaptic pruning STEVENS, BETH CHILDREN'S HOSPITAL CORPORATION MA $586,541
Huntington's Disease 2016 NINDS 5F31NS092230-02 Neuroinflammatory effects on striatal Ca2+-permeable AMPA and kainate receptors BERGER, CARISSA GEORGETOWN UNIVERSITY DC $30,882
Huntington's Disease 2016 NINDS 5R01NS091161-02 Disease-Modifying Genes in Huntington's Diseae GUSELLA, JAMES MASSACHUSETTS GENERAL HOSPITAL MA $610,163
Huntington's Disease 2016 NIGMS 5R01GM062868-14 Folding@Home: Simulating Folding on the Millisecond to Second Timescale PANDE, VIJAY STANFORD UNIVERSITY CA $475,978
Huntington's Disease 2016 NINDS 5F31NS087923-03 Investigation of ApiCCT1 for Huntingtons disease therapeutics OVERMAN, JULIA UNIVERSITY OF CALIFORNIA-IRVINE CA $34,119
Huntington's Disease 2016 NIGMS 5R01GM114306-02 Histone Lysine deMethylation: Structures, Inhibitions and Mechanisms CHENG, XIAODONG EMORY UNIVERSITY GA $288,655
Huntington's Disease 2016 NINDS 5R01NS083534-03 A Longitudinal Analysis Stream for FreeSurfer FISCHL, BRUCE MASSACHUSETTS GENERAL HOSPITAL MA $513,144
Huntington's Disease 2016 NINDS 4R01NS077946-05 Validation of the HD-HRQOL (Huntington disease quality of life measure) CARLOZZI, NOELLE UNIVERSITY OF MICHIGAN MI $566,345
Huntington's Disease 2016 NIA 4R01AG019206-15 Synaptic toxicity of Huntington disease protein LI, XIAO-JIANG EMORY UNIVERSITY GA $316,356
Huntington's Disease 2016 NIBIB 5R01EB020892-02 Optical imaging of small bio-molecules in living cells and tissues by nonlinear Raman microscopy coupled with vibrational tags MIN, WEI COLUMBIA UNIV NEW YORK MORNINGSIDE NY $320,787
Huntington's Disease 2016 NIGMS 5R01GM114494-02 Developing IMS-SID/MAD-MS Instrumentation for Characterizing Intrinsically Disordered Protein Structure VALENTINE, STEPHEN WEST VIRGINIA UNIVERSITY WV $278,173
Huntington's Disease 2016 NINDS 1P01NS092525-01A1 8385 Core A: Administrative Core THOMPSON, LESLIE UNIVERSITY OF CALIFORNIA-IRVINE CA $77,202
Huntington's Disease 2016 NINDS 1P01NS092525-01A1 8386 Core B: Repository Core REIDLING, JACK UNIVERSITY OF CALIFORNIA-IRVINE CA $60,162
Huntington's Disease 2016 NINDS 1P01NS092525-01A1 8387 Project 1: Mechanistic and structural basis for chaperonin-mediated remodeling of mutant HTT CHIU, WAH UNIVERSITY OF CALIFORNIA-IRVINE CA $443,866
Huntington's Disease 2016 NINDS 1P01NS092525-01A1 8388 Project 2: The impact of TRiC reagents on mHTT-induced neuronal degeneration in vitro MOBLEY, WILLIAM UNIVERSITY OF CALIFORNIA-IRVINE CA $316,191
Huntington's Disease 2016 NINDS 1P01NS092525-01A1 8389 Project 3: TRiC modulation of CNS pathogenesis in HD mouse models THOMPSON, LESLIE UNIVERSITY OF CALIFORNIA-IRVINE CA $389,490
Huntington's Disease 2016 NINDS 1R01NS095809-01 Regulation of striatal acetylcholine transmission by cholinergic interneurons FORD, CHRISTOPHER CASE WESTERN RESERVE UNIVERSITY OH $346,719
Huntington's Disease 2016 NINDS 1R01NS096144-01 Huntington's disease: a novel developmental oligodendrogliopathy MEHLER, MARK ALBERT EINSTEIN COLLEGE OF MEDICINE, INC NY $365,313
Huntington's Disease 2016 NINDS 1R01NS096352-01 The Regulation of Synaptic Connectivity and Homeostasis by Huntingtin EROGLU, CAGLA DUKE UNIVERSITY NC $342,543
Huntington's Disease 2016 NINDS 1R01NS096305-01 Mechanism of DNA strand-break repair deficiency in Huntington's disease SARKAR, PARTHA UNIVERSITY OF TEXAS MEDICAL BR GALVESTON TX $460,254
Huntington's Disease 2016 NINDS 5R01NS088192-03 Dynamin-related protein 1, neurodegeneration and Huntington's disease QI, XIN CASE WESTERN RESERVE UNIVERSITY OH $346,719
Huntington's Disease 2016 NINDS 4R01NS041574-15 Pathophysiology of Transgenic Mouse Models of Huntington's Disease LEVINE, MICHAEL UNIVERSITY OF CALIFORNIA LOS ANGELES CA $327,794
Huntington's Disease 2016 NIGMS 5SC1NS095380-02 Mitochondrial DNA and Ape1 in Huntington's Disease AYALA-PENA, SYLVETTE UNIVERSITY OF PUERTO RICO MED SCIENCES PR $339,541
Huntington's Disease 2016 NINDS 5R01NS060115-09 Chemical Fingerprinting MCMURRAY, CYNTHIA UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB CA $553,793
Huntington's Disease 2016 NHGRI 5R01HG008045-03 Families At Risk: Long-term Impact of Huntington's Presymptomatic Genetic Testi MATHEWS, DEBRA JOHNS HOPKINS UNIVERSITY MD $283,500
Huntington's Disease 2016 NINDS 4R01NS085880-04 Development of SLIC, a methodology for synthetic lethal screening in the CNS HEIMAN, MYRIAM BROAD INSTITUTE, INC. MA $354,000
Huntington's Disease 2016 NINDS 4R01NS042842-14 Protein Aggregation and Inclusion Body Formation KOPITO, RON STANFORD UNIVERSITY CA $582,676
Huntington's Disease 2016 NINDS 4R01NS074408-04 Matrix Metalloproteinases: Therapeutic Targets For Huntington's Disease ELLERBY, LISA BUCK INSTITUTE FOR RESEARCH ON AGING CA $424,375
Huntington's Disease 2016 NINDS 5R01NS084298-03 Complement-Microglia Interaction in Synaptic Loss and Neurodegeneration in HD YANG, XIANGDONG UNIVERSITY OF CALIFORNIA LOS ANGELES CA $353,543
Huntington's Disease 2016 NINDS 2R01NS056224-06A1 Deranged calcium signaling and polyglutamine expansion disorders BEZPROZVANNY, ILYA UT SOUTHWESTERN MEDICAL CENTER TX $353,739
Huntington's Disease 2016 NINDS 2R01NS056114-10 ROLE OF CHAIN LENGTH AND SEQUENCE CONTEXTS ON POLYGLUTAMINE OLIGOMERIZATION PAPPU, ROHIT WASHINGTON UNIVERSITY MO $333,594
Huntington's Disease 2016 NINDS 1R01NS089932-01A1 Mechanism of modulation of huntingtin exon 1 aggregation by profilin PAPPU, ROHIT WASHINGTON UNIVERSITY MO $605,543
Huntington's Disease 2016 NINDS 4R01NS055903-08 Growth and Development of the Striatum in Huntington's Disease NOPOULOS, PEGGY UNIVERSITY OF IOWA IA $595,176
Huntington's Disease 2016 NINDS 5R01NS077926-03 Huntingtin proline-rich region modulation of Huntington's disease pathogenesis ZEITLIN, SCOTT UNIVERSITY OF VIRGINIA VA $345,625
Huntington's Disease 2016 NINDS 5R01NS090390-02 Neuroregulatory Mechanisms of PIAS1 and Implications for Huntington's Disease THOMPSON, LESLIE UNIVERSITY OF CALIFORNIA-IRVINE CA $445,378
Huntington's Disease 2016 NINDS 5F32NS089198-04 Mechanisms and effects of GABAbR dephosphorylation during ischemic excitotoxicity WISEMAN, SHARI TUFTS UNIVERSITY BOSTON MA $58,002
Huntington's Disease 2016 NINDS 5R21NS090395-02 Genome editing in HD iPS cells to reduce mutant and total Huntington expression THOMPSON, LESLIE UNIVERSITY OF CALIFORNIA-IRVINE CA $254,075
Huntington's Disease 2016 NIDA 5R01DA026430-08 Role of ABHD6 in 2-AG Signaling STELLA, NEPHI UNIVERSITY OF WASHINGTON WA $344,148
Huntington's Disease 2016 NIGMS 5P20GM104316-03 7898 Discovery of Chemical Probes and Therapeutic Leads FOX, JOSEPH UNIVERSITY OF DELAWARE DE $333,582
Huntington's Disease 2016 NIGMS 5P20GM104316-03 7902 In vitro neural disease models for high throughput screening KLOXIN, APRIL UNIVERSITY OF DELAWARE DE $359,085
Huntington's Disease 2016 NINDS 4R01NS082338-04 Huntington's disease biomarkers and therapeutics DUAN, WENZHEN JOHNS HOPKINS UNIVERSITY MD $389,332
Huntington's Disease 2016 NINDS 2R01NS065874-06 The PPAR-delta pathway in neural function and Huntington's disease neuropathology LA SPADA, ALBERT UNIVERSITY OF CALIFORNIA SAN DIEGO CA $471,121
Huntington's Disease 2016 NINDS 5R01NS089750-02 Exploring the contribution of astrocytes to Huntington disease GRAY, MICHELLE UNIVERSITY OF ALABAMA AT BIRMINGHAM AL $334,855
Huntington's Disease 2016 NINDS 4R01NS085812-04 Selectively inhibited transcription of mutant genes in neurodegenerative disease COHEN, STANLEY STANFORD UNIVERSITY CA $144,430
Huntington's Disease 2016 NIGMS 5R01GM056350-18 Exploring the toxicity of aggregates associated with protein-misfolding diseases LIEBMAN, SUSAN UNIVERSITY OF NEVADA RENO NV $384,056
Huntington's Disease 2016 NINDS 5U01NS082062-03 Identifying Huntington's disease markers by modern statistical learning methods. WANG, YUANJIA COLUMBIA UNIVERSITY HEALTH SCIENCES NY $356,244
Huntington's Disease 2016 NINDS 4R01NS059690-09 Molecular Chaperones and Small Molecules GESTWICKI, JASON UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $417,614
Huntington's Disease 2016 NIGMS 1F32GM119228-01 Engineering Protein Stability Through Phage-Assisted Continuous Evolution WANG, TINA HARVARD UNIVERSITY MA $54,294
Huntington's Disease 2016 NINDS 1F32NS095508-01A1 Enhancing siRNA delivery and efficacy in the brain through conjugation of bioactive, polyunsaturated fatty acids OSBORN, MAIRE UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $56,118
Huntington's Disease 2016 NINDS 1F32NS093813-01A1 Optogenetic Stimulation of Striatal Output Neurons in Mouse Models of Huntingtons Disease BARRY, JOSHUA UNIVERSITY OF CALIFORNIA LOS ANGELES CA $58,002
Huntington's Disease 2016 NINDS 5R01NS076631-04 Genomic and functional analysis of transcriptome changes in Huntington's Disease DAVIDSON, BEVERLY CHILDREN'S HOSP OF PHILADELPHIA PA $606,057
Huntington's Disease 2016 RMAP 5UH3TR000888-04 Exosome based therapeutics in Huntington's disease ARONIN, NEIL UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $980,438
Huntington's Disease 2016 NINDS 5F32NS093786-02 Synaptic calcium dysregulation in Huntington's disease RYSKAMP, DANIEL UT SOUTHWESTERN MEDICAL CENTER TX $57,794
Huntington's Disease 2016 NCCIH 3U01AT008197-02S1 Creatine Safety and Efficacy in HD: Coordination and Statistical Center SCHIFITTO, GIOVANNI UNIVERSITY OF ROCHESTER NY $122,800
Huntington's Disease 2016 NINDS 5R01NS095181-02 Glial huntingtin and neurodegeneration LI, SHI-HUA EMORY UNIVERSITY GA $341,250
Huntington's Disease 2016 NINDS 5R01NS049206-12 Huntington's disease repeat instability and pathogenesis WHEELER, VANESSA MASSACHUSETTS GENERAL HOSPITAL MA $584,699
Huntington's Disease 2016 NINDS 5R01NS095563-02 Nanocarriers Designed to Deliver Nucleic Acids to Brain SANCHEZ-RAMOS, JUAN UNIVERSITY OF SOUTH FLORIDA FL $448,500
Huntington's Disease 2016 NINDS 5R21NS091055-02 Exercise Intervention for Slowing HD Progression MAGNOTTA, VINCENT UNIVERSITY OF IOWA IA $190,625
Huntington's Disease 2016 NINDS 5R21NS095312-02 Comprehensive Synaptome Proteomics Targeting Protein Expression and PTMs in HD ELLERBY, LISA BUCK INSTITUTE FOR RESEARCH ON AGING CA $275,682
Huntington's Disease 2016 NIBIB 2P41EB015909-16 5061 TR&D 2: Quantitative multi-contrast MRI at 3T and 7T. VAN ZIJL, PETER HUGO W. MOSER RES INST KENNEDY KRIEGER MD $182,592
Huntington's Disease 2016 NINDS 1R21NS098137-01 Development of DNAzyme Gene Therapy for Huntington's Disease REINER, ANTON UNIVERSITY OF TENNESSEE HEALTH SCI CTR TN $190,000
Huntington's Disease 2016 NIA 1R36AG053444-01 MODELING HUNTINGTON'S DISEASE WITH STRIATAL NEURONS DIRECTLY CONVERTED FROM PATIENT FIBROBLASTS VICTOR, MATHEUS WASHINGTON UNIVERSITY MO $66,148
Huntington's Disease 2016 NINDS 1R21NS098323-01 Novel 3D brain tissue-based screening assay for targeting microglia in CNS neurodegeneration LO, DONALD DUKE UNIVERSITY NC $238,500
Huntington's Disease 2016 NINDS 5F30NS095450-02 Investigating the Mechanism and Effect of Disease-Associated Increases in the Huntingtin Long 3'UTR Isoform ROMO, LINDSAY UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $27,749
Huntington's Disease 2016 NINDS 1R01NS094456-01A1 Early detection of Huntington's Disease: Longitudinal analysis of basal ganglia and cortical thickness OGUZ, IPEK UNIVERSITY OF PENNSYLVANIA PA $328,693
Huntington's Disease 2016 NINDS 1R01NS094450-01A1 Neural circuit mechanisms underlying cognitive control of sensory-guided behavior MARGOLIS, DAVID RUTGERS, THE STATE UNIV OF N.J. NJ $339,063
Huntington's Disease 2016 NINDS 1R21NS094886-01A1 NG2 cells in Huntington's disease DUAN, WENZHEN JOHNS HOPKINS UNIVERSITY MD $202,500
Huntington's Disease 2016 NIA 1R21AG051046-01A1 Roles of heat shock protein 110 in modulating amyloid neurotoxicity MORANO, KEVIN UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON TX $228,318
Huntington's Disease 2016 NINDS 1R21NS095245-01A1 Global RNA Interference Therapy for Huntingtons Disease MCBRIDE, JODI OREGON HEALTH & SCIENCE UNIVERSITY OR $437,500
Huntington's Disease 2016 NINDS 1F31NS098739-01 The role of RBM3 in Huntingtons disease: pathogenesis and protection RIEDERS, JULIANNE UNIVERSITY OF PENNSYLVANIA PA $43,576
Huntington's Disease 2016 NINDS 4U44NS090616-02 Tolerability of SRX246 in Huntington's Disease Patients BROWNSTEIN, MICHAEL AZEVAN PHARMACEUTICALS, INC. PA $2,214,354
Huntington's Disease 2016 NINDS 1R01NS099136-01 Cortico-basal ganglia connectivity in a non-human primate model of Huntington's disease MCBRIDE, JODI OREGON HEALTH & SCIENCE UNIVERSITY OR $712,873
Huntington's Disease 2016 NINDS 1R01NS099397-01 Structure of Triplet Repeat mRNA in Neurodegenerative Disease WOODSON, SARAH JOHNS HOPKINS UNIVERSITY MD $356,745
Huntington's Disease 2016 NINDS 1R21NS099670-01 Mitochondrial SIRT3 in Huntington's disease DUAN, WENZHEN JOHNS HOPKINS UNIVERSITY MD $244,625
Huntington's Disease 2016 NINDS 1R21NS096603-01A1 EPIGENETIC AND MRNA PROFILING OF STRIATOPALLIDAL NEURONS IN HUNTINGTON'S DISEASE YANO, HIROKO WASHINGTON UNIVERSITY MO $190,625
Huntington's Disease 2016 NINDS 1R01NS094422-01A1 Genetic Correction of Mutant Huntingtin in Vivo ELLERBY, LISA BUCK INSTITUTE FOR RESEARCH ON AGING CA $424,375
Huntington's Disease 2016 NINDS 1R21NS096642-01A1 Addressing the contribution of JNK3 to axonal pathology in Huntington's disease MORFINI, GERARDO UNIVERSITY OF ILLINOIS AT CHICAGO IL $230,266
Huntington's Disease 2016 NINDS 1R01NS100529-01 Identifying Factors Regulating Medium Spiny Neuron Differentiation or Maintenance as Therapeutic Targets for Huntington's Disease using Induced Pluripotent Stem Cells ELLERBY, LISA BUCK INSTITUTE FOR RESEARCH ON AGING CA $699,638
Huntington's Disease 2016 NINDS 3R01NS077946-05S1 Supplement III to Validation of the HD-HRQOL (Huntington disease quality of life measure) CARLOZZI, NOELLE UNIVERSITY OF MICHIGAN MI $33,450
Huntington's Disease 2016 NIGMS 3R01GM100092-01A1S1 Role of Fic Proteins in Cellular Signaling MATTOO, SEEMA PURDUE UNIVERSITY IN $151,461
Huntington's Disease 2016 NINDS 1R56NS096994-01 Cortical Pathophysiology in Mouse Models of Huntington's Disease LEVINE, MICHAEL UNIVERSITY OF CALIFORNIA LOS ANGELES CA $535,235
Huntington's Disease 2016 NIEHS 6R01ES016931-09 Gene-Neurotoxicant Interactions in Huntington Disease BOWMAN, AARON VANDERBILT UNIVERSITY MEDICAL CENTER TN $320,029
Huntington's Disease 2016 NIA 1ZIAAG000329-09 Exercise and brain function in a mouse model of Huntington's Disease. VAN PRAAG, HENRIETTE NIH $168,228
Huntington's Disease 2016 NIA 1ZIAAG000927-09 Magnetic Resonance Imaging and Spectroscopy of Rodent Models of Disease SPENCER, RICHARD NIH $178,235
Huntington's Disease 2016 NCATS 1ZIATR000087-02 Identification of GPR52 antagonists as potential treatments for Huntington Disease FERRER, MARC NIH $37,474
Huntington's Disease 2016 NCATS 1ZIATR000104-02 Identification of small molecules that increase activity of the huntingtin antisense promoter for the potential treatment of Huntington Disease FERRER, MARC NIH $37,474
Huntington's Disease 2016 NCATS 1ZIATR000105-02 Identification of small molecules that decrease the activity of the huntingtin gene promoter for the potential treatment of Huntington Disease FERRER, MARC NIH $37,474


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