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RCDC

Project Listing by Category


Back to Estimates of Funding for Various Research, Condition, and Disease Categories (RCDC) Click the column headings to sort project listings.
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CategoryFYFunding ICProject NumberSub Project #Project TitlePI NameOrg NameState / CountryAmount
ALS 2016 NIEHS 4R01ES022310-04 Association of ALS to gene-environment mediated changes in HDL proteins SIDDIQUE, TEEPU NORTHWESTERN UNIVERSITY AT CHICAGO IL $606,795
ALS 2016 NIDCD 5R01DC013547-03 SPEECH MOVEMENT CLASSIFICATION FOR ASSESSING AND TREATING ALS GREEN, JORDAN MGH INSTITUTE OF HEALTH PROFESSIONS MA $585,316
ALS 2016 NINDS 4R01NS040433-14 Immune Regulation of Neuronal Injury and Repair JONES, KATHRYN INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS IN $463,254
ALS 2016 NINDS 4R01NS057553-10 Animal Models for Studying Human Frontotemporal Dementia GAO, FEN-BIAO UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $329,765
ALS 2016 NINDS 4R01NS078504-05 Disease Mechanisms in Human Ubiquilinopathy SIDDIQUE, TEEPU NORTHWESTERN UNIVERSITY AT CHICAGO IL $502,357
ALS 2016 NIGMS 4R01GM069909-13 Structures and mechanisms of nuclear import and export CHOOK, YUH MIN UT SOUTHWESTERN MEDICAL CENTER TX $333,488
ALS 2016 NINDS 5R21NS091630-02 Statistical Methods for Causal Inference in Observational Studies LONG, QI EMORY UNIVERSITY GA $229,807
ALS 2016 NINDS 5R01NS091836-02 Mechanisms Underlying Excitability Regulation of Motoneuron Types in ALS ELBASIOUNY, SHERIF WRIGHT STATE UNIVERSITY OH $323,750
ALS 2016 NIA 5K01AG049152-02 RNA signatures of frontotemporal dementia and ALS due to C9ORF72 expansion YOKOYAMA, JENNIFER UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $129,472
ALS 2016 NIEHS 4R01ES020395-05 Stress Granules and the Biology of TDP-43 WOLOZIN, BENJAMIN BOSTON UNIVERSITY MEDICAL CAMPUS MA $953,194
ALS 2016 NINDS 5R01NS091540-02 Muscle stem cells: New ALS growth factor therapy and disease model SUZUKI, MASATOSHI UNIVERSITY OF WISCONSIN-MADISON WI $334,688
ALS 2016 NINDS 5R01NS065317-08 Molecular Basis of TDP-43 Proteinopathies: Disease Models and Mechanisms GITLER, AARON STANFORD UNIVERSITY CA $351,023
ALS 2016 NINDS 5R44NS076194-05 Preclinical testing of the splice modulating oligonucleotide LSP-GR1 LUTZ, GORDON LIFESPLICE PHARMA, LLC PA $965,278
ALS 2016 NINDS 5R00NS082376-04 Analysis of the RNA-binding Protein FUS and Its Role in Neurodegenerative Disease SCHWARTZ, JACOB UNIVERSITY OF ARIZONA AZ $259,070
ALS 2016 NHLBI 5R00HL119606-03 Enhanced respiratory plasticity in models of respiratory motor neuron death NICHOLS, NICOLE UNIVERSITY OF MISSOURI-COLUMBIA MO $243,721
ALS 2016 NINDS 5R01NS081303-04 Cellular and Molecular Mechanisms of FUS-related Amyotrophic Lateral Sclerosis PANDEY, UDAI UNIVERSITY OF PITTSBURGH AT PITTSBURGH PA $329,440
ALS 2016 NINDS 5K99NS091538-02 Mechanisms of C9orf72 hexanucleotide repeat expansion caused neurodegeneration in ALS and FTD SUN, SHUYING LUDWIG INSTITUTE FOR CANCER RES LTD CA $93,042
ALS 2016 NINDS 5R01NS090962-02 Re-Establishing Vascular Integrity in ALS via Endothelial Cell Transplant GARBUZOVA-DAVIS, SVITLANA UNIVERSITY OF SOUTH FLORIDA FL $327,031
ALS 2016 NINDS 4R01NS078145-05 Investigating a Toxic Gain-of-Interaction Between FUS/TLS & Stress Granules BOSCO, DARYL UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $359,844
ALS 2016 NINDS 5K08NS082365-03 The Role of Sirtuin 1 Deacetylase in Amyotrophic Lateral Sclerosis HERSKOVITS, ADRIANNA BRIGHAM AND WOMEN'S HOSPITAL MA $192,510
ALS 2016 NINDS 4R01NS078398-05 DEVELOPING A MICRORNA-TARGETED THERAPY FOR ALS MILLER, TIMOTHY WASHINGTON UNIVERSITY MO $332,500
ALS 2016 NIDCD 5R01DC014034-02 Advanced neural decoders for the restoration of communication HENDERSON, JAIMIE STANFORD UNIVERSITY CA $754,087
ALS 2016 NIDCD 5F32DC014382-02 Innovative Biomarkers of Orofacial Dysfunction in Amyotrophic Lateral Sclerosis MCILDUFF, COURTNEY BETH ISRAEL DEACONESS MEDICAL CENTER MA $66,354
ALS 2016 NIEHS 5R01ES024064-02 Environmental Metals, Excitotoxicity and ALS ATCHISON, WILLIAM MICHIGAN STATE UNIVERSITY MI $449,410
ALS 2016 NINDS 5R37NS060698-08 Mechanistic analysis of axonal transport defects in neurodegenerative disease HOLZBAUR, ERIKA UNIVERSITY OF PENNSYLVANIA PA $385,720
ALS 2016 NINDS 5K08NS082364-03 Defining an Electrophysiological Phenotype of ALS Patient-Derived Motor Neurons WAINGER, BRIAN MASSACHUSETTS GENERAL HOSPITAL MA $193,536
ALS 2016 NINDS 5R01NS088689-03 Silencing C9or72 with rAAV Mediated RNAi BROWN, ROBERT UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $360,494
ALS 2016 NINDS 4R01NS072428-04 Role of MMP-9 in selective motor neuron degeneration in ALS PRZEDBORSKI, SERGE COLUMBIA UNIVERSITY HEALTH SCIENCES NY $329,469
ALS 2016 NIEHS 1R43ES025513-01A1 Lake Cyanobacterial Harmful Algal Bloom Mapping and Analysis Platform (CHAB-MAP) TORBICK, NATHAN APPLIED GEOSOLUTIONS, LLC NH $150,743
ALS 2016 NINDS 4R01NS084089-04 Mechanisms of Neurodegeneration in ALS XIA, XUGANG THOMAS JEFFERSON UNIVERSITY PA $339,063
ALS 2016 NINDS 5F32NS090831-02 The contribution of cytoskeleton disruptions in ALS disease pathology DANIELSON, ERIC UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $58,002
ALS 2016 NINDS 5R01NS082304-03 Development of a Multi-Modal Neuroimaging Biomarker for Amyotrophic Lateral Scler WELSH, ROBERT UNIVERSITY OF MICHIGAN MI $1
ALS 2016 NINDS 5R00NS087104-03 Novel mechanisms of actin dynamics underlying cell motility, axon growth, and ALS VITRIOL, ERIC UNIVERSITY OF FLORIDA FL $245,289
ALS 2016 NINDS 4R01NS076471-04 Molecular genetic studies of progranulin regulators in FTLD and ALS RADEMAKERS, ROSA MAYO CLINIC JACKSONVILLE FL $342,344
ALS 2016 NINDS 5R01NS088645-02 Etiological Linkage of DNA Damage/Repair Deficiency in Neurodegenerative Diseases HEGDE, MURALIDHAR METHODIST HOSPITAL RESEARCH INSTITUTE TX $348,617
ALS 2016 NINDS 5R21NS088839-02 Seeded transmission of SOD1 misfolding BORCHELT, DAVID UNIVERSITY OF FLORIDA FL $187,500
ALS 2016 NIA 5P50AG005131-33 5888 Project 2: Disease Mechanisms in Frontotemporal Dementia Linked to C9orf72 Expans LAGIER-TOURENNE, CLOTILDE UNIVERSITY OF CALIFORNIA SAN DIEGO CA $193,123
ALS 2016 NINDS 5R01NS087227-04 Using RNA signatures for therapy development in neurodegeneration due to C9orf72 expansions LAGIER-TOURENNE, CLOTILDE MASSACHUSETTS GENERAL HOSPITAL MA $304,500
ALS 2016 NINDS 4R01NS027036-29 Neurofilaments, SOD1 and Motor Neuron Diseases CLEVELAND, DON LUDWIG INSTITUTE FOR CANCER RES LTD CA $492,551
ALS 2016 NINDS 5R21NS088653-02 Development of a New ALS Mouse Model that Targets Profilin1 and Actin Filaments KIAEI, MAHMOUD UNIV OF ARKANSAS FOR MED SCIS AR $186,250
ALS 2016 NINDS 5R00NS080985-05 TDP-43 acetylation as a pathogenic modification in ALS & related proteinopathies COHEN, TODD UNIV OF NORTH CAROLINA CHAPEL HILL NC $238,169
ALS 2016 NIGMS 5R01GM108975-03 A Conserved Metalloprotease Required for Mitochondrial Maintenance and Protection KHALIMONCHUK, OLEH UNIVERSITY OF NEBRASKA LINCOLN NE $273,189
ALS 2016 NINDS 5F32NS089290-03 The PERKplexity of the integrated stress response in motor neurons and myelinatin DZHASHIASHVILI, YULIA UNIVERSITY OF CHICAGO IL $64,146
ALS 2016 NINDS 5K23NS083715-03 Molecular Imaging of Inflammation in Amyotrophic Lateral Sclerosis (ALS) ATASSI, NAZEM MASSACHUSETTS GENERAL HOSPITAL MA $194,616
ALS 2016 NINDS 5R01NS089640-02 NAD metabolsim and mitochondrial dysfunction in ALS models VARGAS, MARCELO MEDICAL UNIVERSITY OF SOUTH CAROLINA SC $327,031
ALS 2016 NINDS 5R01NS089701-03 Redesign Rat Model for ALS Research ZHOU, HONGXIA THOMAS JEFFERSON UNIVERSITY PA $341,250
ALS 2016 NINDS 5R21NS093244-02 Investigating the contributions of astrocyte gap junctions to ALS disease progression MARAGAKIS, NICHOLAS JOHNS HOPKINS UNIVERSITY MD $202,500
ALS 2016 NINDS 5R01NS089616-02 Investigating disease Mechanisms in C9orf72-linked ALS/FTD WANG, JIOU JOHNS HOPKINS UNIVERSITY MD $354,375
ALS 2016 NINDS 5R01NS093872-02 Metabolic profiling of sporadic ALS patients: from fibroblasts to neurons and back MANFREDI, GIOVANNI WEILL MEDICAL COLL OF CORNELL UNIV NY $530,987
ALS 2016 NIGMS 4R01GM046295-21 Mechanisms and functions of subcellular motility SAXTON, WILLIAM UNIVERSITY OF CALIFORNIA SANTA CRUZ CA $306,139
ALS 2016 NINDS 5R21NS093469-02 Investigating mechanisms of UBQLN2-mediated neurodegenerative disease PAULSON, HENRY UNIVERSITY OF MICHIGAN MI $193,750
ALS 2016 NIA 4P01AG019724-15 5685 Clinical and Administrative MILLER, BRUCE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $562,051
ALS 2016 NIA 4P01AG019724-15 5694 Clinical Criteria MILLER, BRUCE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $256,445
ALS 2016 NIA 1R01NS095793-01 Epigenetic Editing of Mutant C9orf72 LEE, EDWARD UNIVERSITY OF PENNSYLVANIA PA $50,000
ALS 2016 NINDS 1R01NS095793-01 Epigenetic Editing of Mutant C9orf72 LEE, EDWARD UNIVERSITY OF PENNSYLVANIA PA $350,000
ALS 2016 NINDS 1R01NS095962-01 Study on hnRNPA1 Pathobiology in ALS XIA, XUGANG THOMAS JEFFERSON UNIVERSITY PA $341,250
ALS 2016 NIA 1R01NS095969-01 TDP-43 Proteinopathy in ALS-FTD: Mechanism, Target Validation and Biomarker WONG, PHILIP JOHNS HOPKINS UNIVERSITY MD $50,625
ALS 2016 NINDS 1R01NS095969-01 TDP-43 Proteinopathy in ALS-FTD: Mechanism, Target Validation and Biomarker WONG, PHILIP JOHNS HOPKINS UNIVERSITY MD $354,375
ALS 2016 NINDS 4R01NS045893-11 Prospective study of biomarkers and risk factors for ALS incidence and progressio ASCHERIO, ALBERTO HARVARD SCHOOL OF PUBLIC HEALTH MA $453,864
ALS 2016 NINDS 4R01NS078214-05 Active zone loss cause dying back neuropathy in amyotrophic lateral sclerosis NISHIMUNE, HIROSHI UNIVERSITY OF KANSAS MEDICAL CENTER KS $330,313
ALS 2016 NINDS 5R01NS089742-03 C9ORF72 in Motor System Biology and ALS EGGAN, KEVIN HARVARD UNIVERSITY MA $451,171
ALS 2016 NINDS 5R01NS090352-03 Misfolded ALS-linked Profilin-1: a novel therapeutic target BOSCO, DARYL UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $364,766
ALS 2016 NINDS 5R21NS088449-02 Transposable Elements in Frontotemporal Lobar Degeneration HAMMELL, MOLLY COLD SPRING HARBOR LABORATORY NY $240,000
ALS 2016 NINDS 1R21NS096319-01 Modifiers of C9orf72 associated dipeptide protein toxicity in a C. elegans model LAMITINA, SAMUEL UNIVERSITY OF PITTSBURGH AT PITTSBURGH PA $223,491
ALS 2016 NINDS 5R01NS092788-02 Modeling the progression of SOD1-linked motor neuron disease BORCHELT, DAVID UNIVERSITY OF FLORIDA FL $328,125
ALS 2016 NINDS 5R01NS089604-03 TDP-43 and Mitochondrial Dysfunction in ALS WANG, XINGLONG CASE WESTERN RESERVE UNIVERSITY OH $346,719
ALS 2016 NIA 5U01AG045390-03 Longitudinal Evaluation of Familial Frontotemporal Dementia Subjects (LEFFTDS) BOEVE, BRADLEY MAYO CLINIC ROCHESTER MN $1,693,803
ALS 2016 NINDS 5U01AG045390-03 Longitudinal Evaluation of Familial Frontotemporal Dementia Subjects (LEFFTDS) BOEVE, BRADLEY MAYO CLINIC ROCHESTER MN $1,693,803
ALS 2016 NINDS 5R01NS064131-08 Developing neuroprotective strategies for proteinopathy KRAEMER, BRIAN SEATTLE INST FOR BIOMEDICAL/CLINICAL RES WA $295,313
ALS 2016 NINDS 1R01NS092651-01A1 Smad Signaling in Skeletal Muscle as a Biomarker of Disease Progression in ALS KING, PETER UNIVERSITY OF ALABAMA AT BIRMINGHAM AL $321,563
ALS 2016 NCATS 5U54NS092091-03 6482 Project 1 BENATAR, MICHAEL UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $83,638
ALS 2016 NINDS 5U54NS092091-03 6482 Project 1 BENATAR, MICHAEL UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $149,486
ALS 2016 NCATS 5U54NS092091-03 6483 Project 2 BENATAR, MICHAEL UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $196,296
ALS 2016 NINDS 5U54NS092091-03 6483 Project 2 BENATAR, MICHAEL UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $350,839
ALS 2016 NCATS 5U54NS092091-03 6484 Pilot Demonstration BENATAR, MICHAEL UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $26,325
ALS 2016 NINDS 5U54NS092091-03 6484 Pilot Demonstration BENATAR, MICHAEL UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $47,050
ALS 2016 NIA 9R01NS096785-06 Integrating Quality Control: Studies of UBQLN2 in Age-Related Neurodegeneration PAULSON, HENRY UNIVERSITY OF MICHIGAN MI $76,057
ALS 2016 NINDS 9R01NS096785-06 Integrating Quality Control: Studies of UBQLN2 in Age-Related Neurodegeneration PAULSON, HENRY UNIVERSITY OF MICHIGAN MI $547,395
ALS 2016 NINDS 1R01NS091722-01A1 Molecular phenotyping of cortical cell types in multiple rodent models of ALS SCHMIDT, ERIC ROCKEFELLER UNIVERSITY NY $370,781
ALS 2016 NINDS 4R01NS080882-05 GGGGCC hexanucleotide repeat expansions in neurodegenerative disease RADEMAKERS, ROSA MAYO CLINIC JACKSONVILLE FL $152,007
ALS 2016 NINDS 5F31NS092340-02 Defining Motor Neuron-Specific miRNAs in ALS LAWLER, MARIAH WASHINGTON UNIVERSITY MO $30,228
ALS 2016 NINDS 5R37NS040389-13 Molecular Genetic Characterization of SCA8 RANUM, LAURA UNIVERSITY OF FLORIDA FL $626,676
ALS 2016 NINDS 5R21NS092127-02 Does TDP-43 dysfunction in astrocytes trigger motor neuron degeneration? XU, ZUOSHANG UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $251,250
ALS 2016 NINDS 1R21NS093118-01A1 TTR and C9ORF72 in ALS and related disorders VAN BLITTERSWIJK, MARKA MAYO CLINIC JACKSONVILLE FL $248,663
ALS 2016 NINDS 5R01NS063964-07 TDP-43, RNA Metabolism, and ALS/FTD Pathology LINK, CHRISTOPHER UNIVERSITY OF COLORADO CO $338,516
ALS 2016 NINDS 5R01NS093865-02 Defining the mechanisms of dipeptide repeat protein toxicity in C9orf72 ALS/FTD GITLER, AARON STANFORD UNIVERSITY CA $140,241
ALS 2016 NINDS 1R01NS096746-01 AMPK, metabolism and ALS KALB, ROBERT CHILDREN'S HOSP OF PHILADELPHIA PA $492,894
ALS 2016 NIGMS 5R01GM056350-18 Exploring the toxicity of aggregates associated with protein-misfolding diseases LIEBMAN, SUSAN UNIVERSITY OF NEVADA RENO NV $384,056
ALS 2016 NINDS 5R01NS073873-06 Identification of ALS associated genes using whole genome sequencing LANDERS, JOHN UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $690,936
ALS 2016 NINDS 5F30NS092262-02 Investigating V1 interneuron subtype diversity using embryonic stem cells HOANG, PHUONG COLUMBIA UNIVERSITY HEALTH SCIENCES NY $48,576
ALS 2016 NINDS 5P01NS084974-03 6281 Administrative Core PETRUCELLI, LEONARD MAYO CLINIC JACKSONVILLE FL $291,398
ALS 2016 NINDS 5P01NS084974-03 6282 Project 1: Molecular markers and phenotypic heterogeneity in c9FTD/ALS. BOYLAN, KEVIN MAYO CLINIC JACKSONVILLE FL $173,567
ALS 2016 NINDS 5P01NS084974-03 6283 Project 2: RAN translation and RNA-binding protein sequestration in c9FTD/ALS PETRUCELLI, LEONARD MAYO CLINIC JACKSONVILLE FL $33,174
ALS 2016 NINDS 5P01NS084974-03 6284 Project 3: Neuropathology of the multi-proteinopathy of c9FTD/ALS. DICKSON, DENNIS MAYO CLINIC JACKSONVILLE FL $82,856
ALS 2016 NINDS 5P01NS084974-03 6285 Core B: Clinical and Genetics Core BOYLAN, KEVIN MAYO CLINIC JACKSONVILLE FL $357,168
ALS 2016 NINDS 5P01NS084974-03 6286 Core C: Neuropathology DICKSON, DENNIS MAYO CLINIC JACKSONVILLE FL $164,682
ALS 2016 NINDS 5R01NS087070-03 Cyclic EphA4 peptide antagonists for neuroprotection in ALS PASQUALE, ELENA SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE CA $688,311
ALS 2016 NINDS 5R01NS088578-03 Developing ASO Therapy for Repeat Expanded C9orf72 ALS-FTD RAVITS, JOHN UNIVERSITY OF CALIFORNIA SAN DIEGO CA $428,588
ALS 2016 NINDS 4R01NS085207-04 ALS/FTD mutant C9orf72-induced genetic and nuclear pathology in iPS cell models ROTHSTEIN, JEFFREY JOHNS HOPKINS UNIVERSITY MD $354,375
ALS 2016 NINDS 5F32NS092417-02 Identifying the mechanisms of neuronal fate commitment during direct conversion GALLOWAY, KATE UNIVERSITY OF SOUTHERN CALIFORNIA CA $58,002
ALS 2016 NINDS 5R21NS094921-02 Mechanisms of C9orf72-associated dipeptide toxicity LAMITINA, SAMUEL UNIVERSITY OF PITTSBURGH AT PITTSBURGH PA $192,500
ALS 2016 NIGMS 1F31GM119249-01 Investigation of a novel protein complex that couples regulation of lysosomal function to intracellular nutrient availability AMICK, JOSEPH YALE UNIVERSITY CT $43,576
ALS 2016 OD 5U54OD020351-02 5026 Project 6 - Amyotrophic Lateral Sclerosis Project LUTZ, CATHLEEN JACKSON LABORATORY ME $124,432
ALS 2016 NINDS 1R01NS094678-01A1 Investigating a2-chimaerin-dependent motor neuron protection in ALS BEG, ASIM UNIVERSITY OF MICHIGAN MI $331,122
ALS 2016 NINDS 5R21NS095157-02 Modeling Synaptic Vulnerability of a Brainstem Sensorimotor Circuit in a Mouse Model for Amyotrophic Lateral Sclerosis VENUGOPAL, SHARMILA UNIVERSITY OF CALIFORNIA LOS ANGELES CA $231,000
ALS 2016 NINDS 5U54NS091046-03 5987 Data Generation Core - Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells THOMPSON, LESLIE UNIVERSITY OF CALIFORNIA-IRVINE CA $700,364
ALS 2016 RMAP 5U54NS091046-03 5987 Data Generation Core - Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells THOMPSON, LESLIE UNIVERSITY OF CALIFORNIA-IRVINE CA $233,921
ALS 2016 NINDS 5R01NS092067-02 Regulation of glutamate transport in astrocyte subtypes and in ALS ROBINSON, MICHAEL CHILDREN'S HOSP OF PHILADELPHIA PA $464,767
ALS 2016 NINDS 5R01NS091299-02 RNA dysregulation in neurodegeneration ZARNESCU, DANIELA UNIVERSITY OF ARIZONA AZ $321,848
ALS 2016 NINDS 5R01NS091110-02 Treatment of ALS based on transplantation of glial restricted progenitors WALCZAK, PIOTR JOHNS HOPKINS UNIVERSITY MD $354,323
ALS 2016 NINDS 5R21NS091953-02 Mechanisms Mediating NMJ Dennervation MILLIGAN, CAROL WAKE FOREST UNIVERSITY HEALTH SCIENCES NC $193,750
ALS 2016 NINDS 5R21NS091860-02 Investigating the response of FUS/TLS to excitotoxic insult BOSCO, DARYL UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $209,375
ALS 2016 NHLBI 1R42HL132735-01 Jamboxx: Interactive Respiratory Therapy through Music and Gaming DICESARE, MICHAEL MY MUSIC MACHINES, INC. NY $225,000
ALS 2016 NIGMS 1R35GM119790-01 Using naturally-occurring fungal prions as models of neurodegenerative protein misfolding SHEWMAKER, FRANK HENRY M. JACKSON FDN FOR THE ADV MIL/MED MD $207,735
ALS 2016 NINDS 5F30NS093682-02 Evolution of Pathologic RNA-Protein Aggregates in Motor Neuron Disease WHEELER, JOSHUA UNIVERSITY OF COLORADO CO $35,468
ALS 2016 NINDS 5R21NS094918-02 G-quadruplex Structures as Targets and Tools in ALS IVANOV, PAVEL BRIGHAM AND WOMEN'S HOSPITAL MA $221,875
ALS 2016 NINDS 5R43NS095481-02 TDP-43 aggregation inhibitors for the treatment of ALS LARSEN, GLENN AQUINNAH PHARMACEUTICALS, INC. MA $182,737
ALS 2016 NINDS 5R21NS095635-02 A new antibody/RNAi combination therapy strategy for ALS XU, ZUOSHANG UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $251,250
ALS 2016 NIGMS 5F32GM113446-02 Therapeutic genome editing for amyotrophic lateral sclerosis GAJ, THOMAS UNIVERSITY OF CALIFORNIA BERKELEY CA $58,002
ALS 2016 NINDS 1R21NS097749-01 Molecular neuropathology of TDP-43 proteinopathies LEE, EDWARD UNIVERSITY OF PENNSYLVANIA PA $241,250
ALS 2016 NIA 1R01NS097542-01 RNA decay in amyotrophic lateral sclerosis and frontotemporal lobar degeneration BARMADA, SAMI UNIVERSITY OF MICHIGAN MI $387,500
ALS 2016 NIA 1R01NS097545-01 Role of C9orf72 in Neurodegeneration BALOH, ROBERT CEDARS-SINAI MEDICAL CENTER CA $54,687
ALS 2016 NINDS 1R01NS097545-01 Role of C9orf72 in Neurodegeneration BALOH, ROBERT CEDARS-SINAI MEDICAL CENTER CA $382,813
ALS 2016 NINDS 1R01NS097816-01 Understanding SOD1 Kinetics in Amyotrophic Lateral Sclerosis MILLER, TIMOTHY WASHINGTON UNIVERSITY MO $524,052
ALS 2016 NIA 1R01NS097850-01 The Role of C9ORF72 Protein Function in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia ICHIDA, JUSTIN UNIVERSITY OF SOUTHERN CALIFORNIA CA $51,562
ALS 2016 NINDS 1R01NS097850-01 The Role of C9ORF72 Protein Function in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia ICHIDA, JUSTIN UNIVERSITY OF SOUTHERN CALIFORNIA CA $360,938
ALS 2016 NINDS 1R21NS098131-01 Gene Therapy for Upper Airway and Respiratory Insufficiency in an ALS Mouse Model ELMALLAH, MAI UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $237,750
ALS 2016 NIGMS 1R01GM120607-01 Genomic profiling of pathological R-loop formation in human diseases. CHEDIN, FREDERIC UNIVERSITY OF CALIFORNIA AT DAVIS CA $314,000
ALS 2016 NINDS 1R03NS098228-01 Optimization of Bi-Pap and PEG intervention protocols for Amyotrophic Lateral Sclerosis MITCHELL, CASSIE GEORGIA INSTITUTE OF TECHNOLOGY GA $78,900
ALS 2016 NIDCD 1R03DC015075-01A1 Tongue- and Jaw-Specific Contributions to Vowel Acoustic Changes: Towards a Mechanistic Model of Intelligibility Loss and Recovery in Dysarthria MEFFERD, ANTJE VANDERBILT UNIVERSITY MEDICAL CENTER TN $158,000
ALS 2016 NIA 1R01NS094239-01A1 Nucleocytoplasmic transport and nuclear pore disruption in ALS/FTD ROTHSTEIN, JEFFREY JOHNS HOPKINS UNIVERSITY MD $135,856
ALS 2016 NINDS 1R01NS094239-01A1 Nucleocytoplasmic transport and nuclear pore disruption in ALS/FTD ROTHSTEIN, JEFFREY JOHNS HOPKINS UNIVERSITY MD $640,467
ALS 2016 NINDS 1R21NS093439-01A1 Cytohesins, ARF GTP'ases and Neurodegeneration KALB, ROBERT CHILDREN'S HOSP OF PHILADELPHIA PA $252,000
ALS 2016 NINDS 1R21NS090205-01A1 Exploring and enhancing Karyopherin beta-2 disaggregate activity SHORTER, JAMES UNIVERSITY OF PENNSYLVANIA PA $195,953
ALS 2016 NINDS 1R21NS096572-01A1 Development of mouse models for ALS5 and SPG11 DENG, HAN-XIANG NORTHWESTERN UNIVERSITY AT CHICAGO IL $231,750
ALS 2016 NINDS 1R21NS095256-01A1 Pathogenic role of the novel mitochondrial apoptotic protein PSAP in ALS XU, XUEMIN UNIVERSITY OF TENNESSEE KNOXVILLE TN $220,500
ALS 2016 NINDS 1R21NS095273-01A1 Modulating the Nucleopathy caused by FUS Mutants of ALS HAYWARD, LAWRENCE UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $251,250
ALS 2016 NINDS 2R01NS074324-06A1 Neurodegeneration and Proteotoxicity Dissected in C. elegans and Mammals WANG, JIOU JOHNS HOPKINS UNIVERSITY MD $364,973
ALS 2016 NINDS 1R21NS098497-01 A new approach to modeling ALS based on TBK1 mutation in mice XU, ZUOSHANG UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $251,250
ALS 2016 NINDS 5F31NS095698-02 Untargeted metabolite profiling of sporadic ALS patient fibroblasts: identifying mechanisms of the disease SCHWARTZ, BENJAMIN WEILL MEDICAL COLL OF CORNELL UNIV NY $43,576
ALS 2016 NINDS 1R01NS098516-01 Mechanisms of HIPK2 in neurodegeneration HUANG, ERIC UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $346,719
ALS 2016 NIA 1R01NS098819-01 Molecular Characterization of ALS/FTD in a novel C9orf72 BAC mouse model. RANUM, LAURA UNIVERSITY OF FLORIDA FL $141,836
ALS 2016 NINDS 1R01NS098819-01 Molecular Characterization of ALS/FTD in a novel C9orf72 BAC mouse model. RANUM, LAURA UNIVERSITY OF FLORIDA FL $631,805
ALS 2016 NINDS 1R43NS097080-01A1 Patient Motor Neuron Assay System for ALS Drug Discovery DU, ZHONGWEI BRAINXELL, INC. WI $202,277
ALS 2016 NINDS 1R01NS099280-01 Hexanucleotide repeat translation in ALS and Frontotemporal Dementia TODD, PETER UNIVERSITY OF MICHIGAN MI $405,101
ALS 2016 NINDS 1R01NS099638-01 Investigation of ALS caused by mutant CHCHD10 SIDDIQUE, TEEPU NORTHWESTERN UNIVERSITY AT CHICAGO IL $524,743
ALS 2016 NINDS 5K22NS091314-03 Epigenetics In Neurodegenerative Disease: Targeting Histone Modifications in ALS TORRENTE, MARIANA BROOKLYN COLLEGE NY $153,370
ALS 2016 NINDS 1R21NS099766-01 Endogenous petides as markers of abnormal SOD-1 protein in familial and sporadic ALS GERTSMAN, ILYA UNIVERSITY OF CALIFORNIA SAN DIEGO CA $245,005
ALS 2016 NINDS 1R21NS099977-01 SMN dysfunction in FUS-dependent ALS PELLIZZONI, LIVIO COLUMBIA UNIVERSITY HEALTH SCIENCES NY $240,000
ALS 2016 NINDS 1R01NS100023-01 Deconstructing the cellular and molecular basis of SBMA motor neuron disease: From mechanism to therapy LA SPADA, ALBERT UNIVERSITY OF CALIFORNIA SAN DIEGO CA $476,403
ALS 2016 NINDS 1R01NS089586-01A1 Role of Oligodendroglia in the Pathogenesis of ALS KANG, SHIN TEMPLE UNIV OF THE COMMONWEALTH PA $340,104
ALS 2016 NINDS 1R21NS095299-01A1 The role of G3BP1 in mutant SOD1-mediated familial ALS GAL, JOZSEF UNIVERSITY OF KENTUCKY KY $225,750
ALS 2016 NINDS 2R01NS050452-11A1 An In Vitro Model of Stem Cell Innervation of Myotubes HICKMAN, JAMES UNIVERSITY OF CENTRAL FLORIDA FL $481,578
ALS 2016 NINDS 2R44NS089423-02 Development of an information-rich assay for C9ORF72 as a test for ALS and FTD BRAM, ERAN ASURAGEN, INC. TX $619,938
ALS 2016 NINDS 3R01NS063964-07S1 TDP-43, RNA Metabolism, and ALS/FTD Pathology LINK, CHRISTOPHER UNIVERSITY OF COLORADO CO $78,680
ALS 2016 NINDS 4R00NS091538-03 C9orf72 hexanucleotide repeat expansion caused neurodegeneration in ALS and FTD SUN, SHUYING JOHNS HOPKINS UNIVERSITY MD $249,000
ALS 2016 NINDS 3R01NS098819-01S1 Molecular Characterization of ALS/FTD in a novel C9orf72 BAC mouse model. RANUM, LAURA UNIVERSITY OF FLORIDA FL $85,360
ALS 2016 NIA 1ZIAAG000933-09 Genetic etiology of Amyotrophic Lateral Sclerosis TRAYNOR, BRYAN NIH $1,003,499
ALS 2016 NIA 1ZIAAG000934-08 Genetic etiology of Fronto-Temporal Dementia TRAYNOR, BRYAN NIH $547,363
ALS 2016 NIA 1ZIAAG000943-09 Function and Pathogenic Mechanism of VAPB in ALS and Other Motor Neuron Diseases CAI, HUAIBIN NIH $109,473
ALS 2016 NINDS 3R01NS089742-03S1 C9ORF72 in Motor System Biology and ALS EGGAN, KEVIN HARVARD UNIVERSITY MA $50,000
ALS 2016 NIEHS 1ZIAES049005-25 Lead And Other Neurotoxins As Risk Factors For Amyotrophic Lateral Sclerosis SANDLER, DALE NIH $91,610
ALS 2016 NICHD 1ZIAHD008892-08 Mechanisms of Motor Neuron Disease KALER, STEPHEN NIH $252,086
ALS 2016 NINDS 1ZIANS002976-18 Spasticity and Upper Motor Neuron Disorders FLOETER, MARY KAY NIH $228,578
ALS 2016 NINDS 1ZIANS003146-02 Natural history and biomarker discovery in C9orf72 Amyotrophic lateral sclerosis and frontotemporal dementia FLOETER, MARY KAY NIH $1,295,275


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