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RCDC

Project Listing by Category


Back to Estimates of Funding for Various Research, Condition, and Disease Categories (RCDC) Click the column headings to sort project listings.
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CategoryFYFunding ICProject NumberSub Project #Project TitlePI NameOrg NameState / CountryAmount
Orphan Drug 2015 NIAID 1K22AI104800-01 Characterization of the arenavirus glycoprotein complex and mechanism of fusion BRINDLEY, MELINDA UNIVERSITY OF GEORGIA GA $161,200
Orphan Drug 2015 NCI 1K22CA181550-01 Targeting defective DNA repair for the prevention of BRCA1-associated cancers ALLI, ELIZABETH WAKE FOREST UNIVERSITY HEALTH SCIENCES NC $162,000
Orphan Drug 2015 NINDS 5U01NS061795-05 Biostatistics and Data Management for a Trial of Corticosteroid Regimens in DMD MCDERMOTT, MICHAEL UNIVERSITY OF ROCHESTER NY $550,000
Orphan Drug 2015 NHLBI 5R01HL108979-04 "Neutrophil Elastase Links Idiopathic Pulmonary Fibrosis and Lung Cancer" HOUGHTON, A. MCGARRY FRED HUTCHINSON CANCER RESEARCH CENTER WA $422,171
Orphan Drug 2015 NCI 5K08CA151892-05 Targeting SRC Signaling Pathways to Promote Cell Cycle Arrest in Ovarian Cancer SIMPKINS, FIONA UNIVERSITY OF PENNSYLVANIA PA $30,798
Orphan Drug 2015 NCI 5K22CA178269-02 Quantify treatment response in IDH1 mutant glioma patients with metabolic MRI ANDRONESI, OVIDIU MASSACHUSETTS GENERAL HOSPITAL MA $200,418
Orphan Drug 2015 NIAID 1U19AI111224-01 7574 Animal Models Core RAYCHAUDHURI, SOUMYA BRIGHAM AND WOMEN'S HOSPITAL MA $287,243
Orphan Drug 2015 NIAID 5R01AI025038-23 Leishmania antigens defined by human immune responses REED, STEVEN INFECTIOUS DISEASE RESEARCH INSTITUTE WA $473,205
Orphan Drug 2015 NIAID 4R37AI032042-22 Methods for Evaluating Vaccine Efficacy HALLORAN, M FRED HUTCHINSON CANCER RESEARCH CENTER WA $507,032
Orphan Drug 2015 NIAID 5R01AI047798-15 PLASMEPSIN V FUNCTION IN MALARIA PARASITES GOLDBERG, DANIEL WASHINGTON UNIVERSITY MO $157,500
Orphan Drug 2015 NIAID 5R01AI095178-04 T cell immunity to Plasmodium sporozoite immunization HARTY, JOHN UNIVERSITY OF IOWA IA $423,281
Orphan Drug 2015 NICHD 5R01HD068174-05 Antimalarial Pharmacology in HIV Coinfected Children and Pregnant Women in Uganda AWEEKA, FRANCESCA UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $503,880
Orphan Drug 2015 NIAID 5R01AI064768-10 Biology of lipoamide dehydrogenase and 2-hydroxy-3-oxoadipate synthase in Mtb NATHAN, CARL WEILL MEDICAL COLL OF CORNELL UNIV NY $920,600
Orphan Drug 2015 NIAID 5R01AI088075-05 Characterization of Pupylation in Mycobacterium tuberculosis DARWIN, KATERINA NEW YORK UNIVERSITY SCHOOL OF MEDICINE NY $380,250
Orphan Drug 2015 NIAID 5R44AI091224-05 Drug Discovery from Slow Growing and Rare Microbial Species SPOERING, AMY NOVOBIOTIC PHARMACEUTICALS, LLC MA $981,599
Orphan Drug 2015 NCI 5R01CA085180-14 Epstein-Barr Virus LMP1-Mediated Oncogenecity KIEFF, ELLIOTT BRIGHAM AND WOMEN'S HOSPITAL MA $701,405
Orphan Drug 2015 NIAID 5R01AI103280-03 FOSMIDOMYCIN RESISTANCE IN PLASMODIUM FALCIPARUM ODOM, AUDREY WASHINGTON UNIVERSITY MO $342,000
Orphan Drug 2015 NIAID 5R01AI104488-02 A Nurse Case Management Intervention to Improve MDR-TB/HIV Coinfection Outcomes FARLEY, JASON JOHNS HOPKINS UNIVERSITY MD $643,688
Orphan Drug 2015 NIGMS 5R01GM067871-12 Structural Requirements for Sterol 14alpha-Demethylases LEPESHEVA, GALINA VANDERBILT UNIVERSITY TN $343,768
Orphan Drug 2015 NCI 5F30CA176922-02 Recombinant Polymers for Transarterial Chemoembolization of Liver Cancer POURSAID, AZADEH UNIVERSITY OF UTAH UT $33,319
Orphan Drug 2015 NIAID 5U01AI088650-05 Myeloid-lineage cells and immunopathology in Leishmania braziliensis SCOTT, PHILLIP UNIVERSITY OF PENNSYLVANIA PA $572,098
Orphan Drug 2015 NIAID 5R01AI088204-05 The molecular mechanism of Aire: partnering with DNA-PK MATHIS, DIANE HARVARD MEDICAL SCHOOL MA $423,750
Orphan Drug 2015 NHLBI 5R01HL107974-04 Lentivirus-based positive/negative selection in minimally ablative transplants GAENSLER, KARIN UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $576,603
Orphan Drug 2015 NINDS 5R01NS072114-05 Neuronal nicotinic receptor modulation and cerebellar ataxias WECKER, LYNN UNIVERSITY OF SOUTH FLORIDA FL $363,947
Orphan Drug 2015 NCI 5R21CA175671-03 Differentiation Therapy of Uveal Melanoma Micrometastases TRIOZZI, PIERRE WAKE FOREST UNIVERSITY HEALTH SCIENCES NC $206,644
Orphan Drug 2015 NCI 5R01CA158415-04 Heterocellular 3D ovarian tumor arrays for imaging and mechanistic combinations HASAN, TAYYABA MASSACHUSETTS GENERAL HOSPITAL MA $356,850
Orphan Drug 2015 NINDS 5F31NS083258-02 Polarized transport in nervous system development and disease in zebrafish CAMPBELL, PHILIP ALBERT EINSTEIN COLLEGE OF MEDICINE NY $43,120
Orphan Drug 2015 NIAID 5R01AI087915-05 Host determinants of protection against tuberculosis in adolescents SCRIBA, THOMAS UNIVERSITY OF CAPE TOWN SO AFR $641,458
Orphan Drug 2015 NIAID 5R01AI103947-03 Lead optimization of DHODH inhibitors for malaria PHILLIPS, MARGARET UT SOUTHWESTERN MEDICAL CENTER TX $595,447
Orphan Drug 2015 NIAID 5R21AI109447-02 Preparation of trypanosome cdc2-related kinase 9 for high throughput screening GUNZL, ARTHUR UNIVERSITY OF CONNECTICUT SCH OF MED/DNT CT $256,846
Orphan Drug 2015 NCI 5R01CA051210-23 Biochemical and molecular studies on NQO1. Design of less toxic Hsp90 inhibitors ROSS, DAVID UNIVERSITY OF COLORADO DENVER CO $312,470
Orphan Drug 2015 NCI 5R01CA142873-06 The GNAQ pathway as a therapeutic target in uveal melanoma BASTIAN, BORIS UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $310,970
Orphan Drug 2015 NIGMS 5R01GM097327-03 Examining the role of Cbk1/NDR kinase in regulating mRNA localization LUCA, FRANCIS UNIVERSITY OF PENNSYLVANIA PA $312,000
Orphan Drug 2015 NCI 5R01CA072937-13 Interactions Between Cytotoxic and Antiangiogenic Drugs GALLO, JAMES ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI NY $229,022
Orphan Drug 2015 NHLBI 5R01HL105470-04 Improving Inhaled Drug Delivery with Self-dispersing Liquids GAROFF, STEPHEN CARNEGIE-MELLON UNIVERSITY PA $468,886
Orphan Drug 2015 NCI 5R21CA176032-02 A Novel Agent with Dual Functions to Treat Head and Neck Cancer TOBACK, FREDERICK UNIVERSITY OF CHICAGO IL $171,825
Orphan Drug 2015 NICHD 5R01HD062484-05 Pharmacogenetic Determinants of Vincristine Toxicity and Response RENBARGER, JAMIE INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS IN $493,265
Orphan Drug 2015 NCI 5R01CA166413-03 Mechanisms and Function of Autophagy in Cancer JIANG, XUEJUN SLOAN-KETTERING INST CAN RESEARCH NY $366,860
Orphan Drug 2015 NCI 5R21CA182820-02 Phosphorylated Form of Activated IKKbeta and Pancreatic Cancer NATARAJAN, AMARNATH UNIVERSITY OF NEBRASKA MEDICAL CENTER NE $196,403
Orphan Drug 2015 NIAID 5R37AI034885-22 Peroxides for Chemotherapy of Malaria and Cancer POSNER, GARY JOHNS HOPKINS UNIVERSITY MD $466,227
Orphan Drug 2015 NIAID 5R21AI105657-02 Connecting drugs to pathways using malaria parasite transcript profiles FERDIG, MICHAEL UNIVERSITY OF NOTRE DAME IN $190,000
Orphan Drug 2015 NIAID 2R44AI100401-03 Broad Spectrum Antiviral Nucleoside Phosphonate Analogs LIPKA, ELKE TSRL, INC. MI $997,904
Orphan Drug 2015 NIBIB 5R21EB017980-02 Engineering of multi-functional nucleolin-targeted nucleic acid delivery system. ZHANG, SURONG UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $209,375
Orphan Drug 2015 NCI 5R01CA172582-03 Alpha Radioimmunotherapy for Lymphoma Treatment SANDMAIER, BRENDA FRED HUTCHINSON CANCER RESEARCH CENTER WA $634,846
Orphan Drug 2015 NINDS 5R03NS081260-02 In vivo longitudinal assessment of methylene blue for Huntington's disease THOMPSON, LESLIE UNIVERSITY OF CALIFORNIA-IRVINE CA $77,250
Orphan Drug 2015 NIAID 5UM1AI069421-09 GHESKIO HIV Clinical Trial Unit PAPE, JEAN GHESKIO CENTER HAITI $919,160
Orphan Drug 2015 NIAID 5UM1AI069432-09 The UCSD CD4 Collaborative Clinical Trial Unit BENSON, CONSTANCE UNIVERSITY OF CALIFORNIA SAN DIEGO CA $103,303
Orphan Drug 2015 NIAID 5UM1AI069476-08 The FIOCRUZ Therapeutic and Prevention HIV/AIDS Clinical Trials Unit GRINSZTEJN, BEATRIZ FUNDACAO OSWALDO CRUZ BRAZIL $1
Orphan Drug 2015 NIAID 5UM1AI069521-09 Stellenbosch University Clinical Trials Unit (SUN-CTU) COTTON, MARK STELLENBOSCH UNIVERSITY TYGERBERG CAMPUS SO AFR $1,155,500
Orphan Drug 2015 NIDDK 5R01DK100595-02 Regulation of Globin Gene Switching by O-GlcNAc Post-Translational Modification PETERSON, KENNETH UNIVERSITY OF KANSAS MEDICAL CENTER KS $262,740
Orphan Drug 2015 NCI 5R01CA166077-03 Screening for modulators of glioma stem cells differentiation TANNOUS, BAKHOS MASSACHUSETTS GENERAL HOSPITAL MA $357,979
Orphan Drug 2015 NINDS 5R21NS085532-02 Small molecule screen to suppress expression of mutant huntington MARGOLIS, RUSSELL JOHNS HOPKINS UNIVERSITY MD $202,500
Orphan Drug 2015 NCI 5R01CA148688-05 The ALK receptor tyrosine kinase as a therapeutic target in neuroblastoma GEORGE, RANI DANA-FARBER CANCER INST MA $363,125
Orphan Drug 2015 NIAID 5R21AI105656-02 pH and glucose sensing in Trypanosoma brucei glycosomes CHRISTENSEN, KENNETH CLEMSON UNIVERSITY SC $183,936
Orphan Drug 2015 NCI 5R01CA172380-03 Determining the Roles of ATRX and DAXX Abnormalities in Cancer Telomere Biology MEEKER, ALAN JOHNS HOPKINS UNIVERSITY MD $335,820
Orphan Drug 2015 NCI 5R01CA181450-02 Pancreatic Ductal Adenocarcinoma is a disease of constitutive autophagy ZEH, HERBERT UNIVERSITY OF PITTSBURGH AT PITTSBURGH PA $319,550
Orphan Drug 2015 NIDDK 5R01DK052962-12 Novel Globin Gene Modulators PERRINE, SUSAN BOSTON UNIVERSITY MEDICAL CAMPUS MA $356,048
Orphan Drug 2015 NIAID 5K23AI091623-05 Phase II Trial of Vorinostat plus Tacrolimus and Mycophenolate to Prevent GVHD CHOI, SUNG UNIVERSITY OF MICHIGAN MI $132,300
Orphan Drug 2015 NCI 5R01CA156177-05 Targeted Photoactivable Nanocells: Image-based Drug Delivery and Dosimetry in GBM HASAN, TAYYABA MASSACHUSETTS GENERAL HOSPITAL MA $498,135
Orphan Drug 2015 NCI 5R01CA176001-02 Mechanisms of Action for KCN1 in the Control of Uveal Melanoma Metastasis GROSSNIKLAUS, HANS EMORY UNIVERSITY GA $323,700
Orphan Drug 2015 NHLBI 5R01HL118312-02 Nanotechnology Approach for Inhalation Treatment of Pulmonary Fibrosis MINKO, TAMARA RUTGERS, THE STATE UNIV OF N.J. NJ $467,743
Orphan Drug 2015 NCI 5P30CA016086-39 8692 Clinical Research GOLDBERG, RICHARD UNIV OF NORTH CAROLINA CHAPEL HILL NC $178,535
Orphan Drug 2015 NCI 5R01CA168448-03 Next Generation Oncolytic Adenovirus for Advanced Pancreatic Cancer Treatment YAMAMOTO, MASATO UNIVERSITY OF MINNESOTA MN $315,400
Orphan Drug 2015 NIAID 5R21AI110078-02 Strategy for anti-tuberculosis therapy BERMUDEZ, LUIZ OREGON STATE UNIVERSITY OR $182,500
Orphan Drug 2015 NIDDK 5R01DK048252-21 Transgene Persistence in Liver Gene Therapy GROMPE, MARKUS OREGON HEALTH & SCIENCE UNIVERSITY OR $369,057
Orphan Drug 2015 NEI 5R01EY002422-34 Mechanisms and Therapeutic Treatments for Inherited Retinal Degenerative Diseases MOLDAY, ROBERT UNIVERSITY OF BRITISH COLUMBIA CANADA $262,601
Orphan Drug 2015 NINDS 5P30NS045758-10 5284 Ohio State Neuroscience Center Core KAUR, BALVEEN OHIO STATE UNIVERSITY OH $72,710
Orphan Drug 2015 NCI 5R01CA174861-02 Novel Theranostics for Pancreatic Cancer DAVYDOVA, JULIA UNIVERSITY OF MINNESOTA MN $319,031
Orphan Drug 2015 NHLBI 5R01HL118390-02 Membrane Serine Protease Activities in Protease Activated Receptor Signaling ANTALIS, TONI UNIVERSITY OF MARYLAND BALTIMORE MD $377,994
Orphan Drug 2015 NIGMS 5R01GM098956-05 Ras18-mediated Fanconi Anemia pathway activation in response to camptothecin PALLE, KOMARAIAH UNIVERSITY OF SOUTH ALABAMA AL $228,690
Orphan Drug 2015 NINDS 5R01NS037918-17 Novel Lysosomal Enzyme Deficient in Batten Disease LOBEL, PETER RBHS-ROBERT WOOD JOHNSON MEDICAL SCHOOL NJ $347,813
Orphan Drug 2015 NINDS 5R21NS084392-02 Therapeutic targeting of aberrant glial function during Juvenile Batten Disease KIELIAN, TAMMY UNIVERSITY OF NEBRASKA MEDICAL CENTER NE $376,250
Orphan Drug 2015 NCI 5R00CA168987-03 Discovering genomic rearrangements under selection in serious ovarian cancer SALZMAN, JULIA STANFORD UNIVERSITY CA $234,786
Orphan Drug 2015 NCI 5R21CA173120-02 Therapy of pancreatic cancer with 212Pb-labeled B7-H3 specific Ab and LDE225 BUCHSBAUM, DONALD UNIVERSITY OF ALABAMA AT BIRMINGHAM AL $201,799
Orphan Drug 2015 NINDS 5R01NS040433-13 Immune Regulation of Neuronal Injury and Repair JONES, KATHRYN INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS IN $524,000
Orphan Drug 2015 NCI 5R03CA175462-02 Trial Participation Decision Making in Ovarian Cancer Patients and Their Families RADECKI BREITKOPF, CARMEN MAYO CLINIC ROCHESTER MN $79,500
Orphan Drug 2015 NHLBI 5R01HL121264-02 Endothelialized microfluidics for sickle cell disease research & drug discovery LAM, WILBUR EMORY UNIVERSITY GA $388,211
Orphan Drug 2015 NINDS 5R44NS076194-04 Preclinical testing of the splice modulating oligonucleotide LSP-GR1 LUTZ, GORDON LIFESPLICE PHARMA, LLC PA $1,033,937
Orphan Drug 2015 NIAID 5K22AI104801-02 Functional Analysis of Regions of Introgression Between Species of Coccidioides BARKER, BRIDGET TRANSLATIONAL GENOMICS RESEARCH INST AZ $106,895
Orphan Drug 2015 NCI 5R01CA167511-03 Translation of Novel Therapeutic Targets in Multiple Myeloma STEWART, ALEXANDER MAYO CLINIC ARIZONA AZ $431,907
Orphan Drug 2015 NIMH 5R01MH093372-04 Epigenetic Regulation of Ube3a as a Treatment for Angelman Syndrome PHILPOT, BENJAMIN UNIV OF NORTH CAROLINA CHAPEL HILL NC $589,741
Orphan Drug 2015 NIAID 1R21AI114507-01 Validation of RelA as a Target for Mycobacterium Tuberculosis Persisters KARAKOUSIS, PETROS JOHNS HOPKINS UNIVERSITY MD $202,500
Orphan Drug 2015 NIAID 5R01AI051334-12 Extracellular Matix Adhesins of Treponema pallidum CAMERON, CAROLINE UNIVERSITY OF VICTORIA CANADA $241,687
Orphan Drug 2015 NIAID 5R21AI107457-02 Identification of protective proteins of Francisella using a novel comparative im SHARMA, JYOTIKA UNIVERSITY OF NORTH DAKOTA ND $215,397
Orphan Drug 2015 NCI 5R21CA175840-02 Neuroplasticity-Based Cognitive Remediation for Pediatric Brain Tumor Survivors COMPAS, BRUCE VANDERBILT UNIVERSITY TN $165,389
Orphan Drug 2015 NCI 5P30CA006516-50 6051 Gynecologic Cancers BIRRER, MICHAEL MASSACHUSETTS GENERAL HOSPITAL MA $93,399
Orphan Drug 2015 NIBIB 5R21EB017986-02 Magnetic Nanocomposites for Catheter-Directed Drug Delivery to Liver Tumors KIM, DONG-HYUN NORTHWESTERN UNIVERSITY AT CHICAGO IL $231,750
Orphan Drug 2015 NHLBI 5R01HL113574-03 Metabolites, Sickle Cell Disease, and Novel Therapeutics XIA, YANG UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON TX $374,300
Orphan Drug 2015 NCI 5R01CA166144-04 Development of Therapeutic CD59 inhibitor for treating B-cell malignancies QIN, XUEBIN TEMPLE UNIV OF THE COMMONWEALTH PA $327,872
Orphan Drug 2015 NCI 5R01CA154228-05 Targeting vFLIP for the treatment of KSHV-associated malignancies CESARMAN, ETHEL WEILL MEDICAL COLL OF CORNELL UNIV NY $350,675
Orphan Drug 2015 NIGMS 5R01GM105691-02 MegaTALS: hyperspecific reagents for targeted gene modification and correction STODDARD, BARRY FRED HUTCHINSON CANCER RESEARCH CENTER WA $334,400
Orphan Drug 2015 NHLBI 5R01HL098329-05 Fibrocytes in human pulmonary fibrosis MEHRAD, BORNA UNIVERSITY OF VIRGINIA VA $541,653
Orphan Drug 2015 NIAID 5R01AI104952-03 HTS for bactericidal inhibitors of M. tuberculosis copper resistance mechanisms WOLSCHENDORF, FRANK UNIVERSITY OF ALABAMA AT BIRMINGHAM AL $367,500
Orphan Drug 2015 NIAID 5R01AI095686-05 Structural Vaccinology of the Malaria Sporozoite Surface Sheath SPRINGER, TIMOTHY CHILDREN'S HOSPITAL CORPORATION MA $455,381
Orphan Drug 2015 NIAID 5R21AI101566-02 Mining marine microbial natural products for anthelmintics leads FENICAL, WILLIAM UNIVERSITY OF CALIFORNIA SAN DIEGO CA $193,750
Orphan Drug 2015 NIAID 5U19AI109764-02 8339 Application of PCMV technology to the development of killed whole cell oral vaccines MEKALANOS, JOHN HARVARD MEDICAL SCHOOL MA $362,449
Orphan Drug 2015 NCI 5R01CA164605-04 Hdac3 as a therapeutic target in BCL6-dependent lymphoma HIEBERT, SCOTT VANDERBILT UNIVERSITY TN $403,135
Orphan Drug 2015 NINDS 5R21NS085612-02 A genome-wide phenotypic screen for modifiers of SMN expression and function PELLIZZONI, LIVIO COLUMBIA UNIVERSITY HEALTH SCIENCES NY $200,000
Orphan Drug 2015 NIAID 5R21AI110335-02 Adjunctive immune modulation to improve TB treatment SUBBIAN, SELVAKUMAR RBHS-NEW JERSEY MEDICAL SCHOOL NJ $198,750
Orphan Drug 2015 NIAID 5R01AI105422-03 An adjuvant that promotes TH1/TH17 and CD8 T cells in a tuberculosis vaccine FLYNN, JOANNE UNIVERSITY OF PITTSBURGH AT PITTSBURGH PA $1,027,582
Orphan Drug 2015 NIGMS 5R01GM060987-14 Replication of Simple DNA Repeats MIRKIN, SERGEI TUFTS UNIVERSITY MEDFORD MA $334,085
Orphan Drug 2015 NINDS 5R01NS078398-04 DEVELOPING A MICRORNA-TARGETED THERAPY FOR ALS MILLER, TIMOTHY WASHINGTON UNIVERSITY MO $332,500
Orphan Drug 2015 NHLBI 5R01HL118000-02 Mining a microRNA Regulated Gene Network to Rescue CFTR-DeltaF508 Function MCCRAY, PAUL UNIVERSITY OF IOWA IA $472,131
Orphan Drug 2015 NHLBI 1R01HL125228-01 Mineralocorticoid receptor and abdominal aortic aneurysm GONG, MING UNIVERSITY OF KENTUCKY KY $531,469
Orphan Drug 2015 NIGMS 1SC1CA199810-01 Novel Nanotechnology Platform for Breast Cancer Treatment AKALA, EMMANUEL HOWARD UNIVERSITY DC $377,500
Orphan Drug 2015 NIAID 5R01AI104589-03 TB Surrogate Markers for Assessing Reponse to Treatment (TB SMART Study) NAHID, PAYAM UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $1,154,896
Orphan Drug 2015 NIAID 5R01AI104621-03 Antibody immunotherapeutics for biodefense against Lassa virus GARRY, ROBERT TULANE UNIVERSITY OF LOUISIANA LA $1,010,001
Orphan Drug 2015 NIAID 5F32AI102567-03 Identifaction of the genetic basis of primaquine resistance in malaria parasites FLANNERY, ERIKA UNIVERSITY OF CALIFORNIA SAN DIEGO CA $56,042
Orphan Drug 2015 NCI 5F32CA183215-02 Defining the Tn-glycoproteome of in situ colorectal tumors and mechanisms of Tn e HANES, MELINDA EMORY UNIVERSITY GA $59,966
Orphan Drug 2015 NIA 2P01AG002132-34A1 8440 Project 3: Assembly and structures of Abeta peptides. DEGRADO, WILLIAM UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $298,852
Orphan Drug 2015 NHLBI 5R01HL078888-08 Genomics and pharmacodynamics of statin-related rhabdomyolysis PSATY, BRUCE UNIVERSITY OF WASHINGTON WA $614,753
Orphan Drug 2015 NCI 5R01CA129536-08 Cell death regulation in proteotoxic therapy ZONG, WEI-XING STATE UNIVERSITY NEW YORK STONY BROOK NY $316,059
Orphan Drug 2015 NINDS 5R01NS037704-16 Molecular Markers as Predictors of Outcome in Gliomas POLLACK, IAN UNIVERSITY OF PITTSBURGH AT PITTSBURGH PA $333,281
Orphan Drug 2015 NHLBI 1P01HL119165-01A1 8472 Targeting Anti-Fibrotic Therapies for IPF HAGOOD, JAMES PROTEOGENOMICS RESEARCH INSTIT/SYS/ MED CA $526,349
Orphan Drug 2015 NHLBI 1P01HL119165-01A1 8473 Targeting TGF-b Inhibitors and PPAR-y Agonists To Enhance IPF Therapy BOROK, ZEA PROTEOGENOMICS RESEARCH INSTIT/SYS/ MED CA $564,765
Orphan Drug 2015 NCCAM 1R15AT008546-01 Anthelmintic Activity of Plant Natural Products Against the Hookworm Ancylostoma BELOFSKY, GIL CENTRAL WASHINGTON UNIVERSITY WA $361,065
Orphan Drug 2015 NIAID 5R01AI108819-02 Characterization of isoprenoid biosynthesis in human malaria gametocytes CASSERA, MARIA VIRGINIA POLYTECHNIC INST AND ST UNIV VA $394,848
Orphan Drug 2015 NHLBI 5K23HL116656-03 Lung Transplant donor: prediction, evaluation, and mechanism CANTU, EDWARD UNIVERSITY OF PENNSYLVANIA PA $159,921
Orphan Drug 2015 NIAAA 5P50AA011999-17 8467 Functional Dissection of EtOH-med Self-renew of Liver Tumor-Int Cells via TLR4 MACHIDA, KEIGO UNIVERSITY OF SOUTHERN CALIFORNIA CA $198,195
Orphan Drug 2015 NIGMS 5SC2GM099595-03 Total Synthesis and Evaluation of Taumycin A and Analogs as Chemotherapeutics for MAIO, WILLIAM NEW MEXICO STATE UNIVERSITY LAS CRUCES NM $146,000
Orphan Drug 2015 NHLBI 5P01HL112761-03 7685 FIX GENE THERAPY AND ROLE OF AAV NAb SAMULSKI, RICHARD UNIV OF NORTH CAROLINA CHAPEL HILL NC $171,400
Orphan Drug 2015 NHLBI 5P01HL112761-03 5691 FIX GENE THERAPY AND ROLE OF AAV NAb SAMULSKI, RICHARD UNIV OF NORTH CAROLINA CHAPEL HILL NC $171,398
Orphan Drug 2015 NIAID 5R21AI109464-02 Inhibition of Ebolavirus Entry by IFITM2 Protein LIU, SHAN-LU UNIVERSITY OF MISSOURI-COLUMBIA MO $187,602
Orphan Drug 2015 NHLBI 5R44HL117511-03 Bioengineered Recombinant FVIII DENNING, GABRIELA EXPRESSION THERAPEUTICS GA $673,613
Orphan Drug 2015 NIAID 1R01AI114685-01 Hit-to-lead discovery for sleeping sickness via industry-academic partnership POLLASTRI, MICHAEL NORTHEASTERN UNIVERSITY MA $554,299
Orphan Drug 2015 NINDS 5R01NS082286-03 Phase II Trial of SGS-742 in Succinic Semialdehyde Dehydrogenase Deficiency GIBSON, K MICHAEL WASHINGTON STATE UNIVERSITY WA $174,168
Orphan Drug 2015 NCI 1R01CA190498-01 gp130 as a novel therapeutic target in ovarian cancer NEAMATI, NOURI UNIVERSITY OF MICHIGAN MI $376,907
Orphan Drug 2015 NCI 1R01CA190237-01 Targeting BRCA Deficient Cells for Killing POMERANTZ, RICHARD TEMPLE UNIV OF THE COMMONWEALTH PA $356,850
Orphan Drug 2015 NIAID 1R01AI114609-01 A biodegradable nano-microparticle prime-boost vaccine strategy DINGLASAN, RHOEL DAVID JOHNS HOPKINS UNIVERSITY MD $405,000
Orphan Drug 2015 NCI 5P30CA046934-27 8115 LUNG, HEAD AND NECK CANCERS MILLER, YORK UNIVERSITY OF COLORADO DENVER CO $36,526
Orphan Drug 2015 NCI 5R01CA138401-06 HSP27: A modulator and therapeutic target of SPARC-induced glioma invasion. REMPEL, SANDRA SPECTRUM HEALTH HOSPITALS MI $299,552
Orphan Drug 2015 NCI 1R01CA190617-01 Itraconazole Analogues to Treat Medulloblastoma HADDEN, MATTHEW UNIVERSITY OF CONNECTICUT STORRS CT $364,247
Orphan Drug 2015 NIAID 5K23AI102639-02 Rifampicin Malabsorption in HIV+ Patients: Mechanisms and Recovery after HAART VINNARD, CHRISTOPHER DREXEL UNIVERSITY PA $120,960
Orphan Drug 2015 NIAID 5R21AI111739-02 Development of an Oral Carbapenem Drug for Treatment of Drug Resistant TB LAMICHHANE, GYANU JOHNS HOPKINS UNIVERSITY MD $217,406
Orphan Drug 2015 NHLBI 5R01HL113655-04 Regulation of alveolar epithelial homeostasis in acute lung injury WANG, JIERU UNIVERSITY OF PITTSBURGH AT PITTSBURGH PA $379,225
Orphan Drug 2015 NIAID 1R01AI114900-01 Novel Reporter Phages to Detect Complex TB Drug Resistance and Persistence LARSEN, MICHELLE ALBERT EINSTEIN COLLEGE OF MEDICINE NY $210,346
Orphan Drug 2015 NIAID 5R01AI093351-05 Preclinical Development of a Tularemia Vaccine HUNTLEY, JASON UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS OH $344,949
Orphan Drug 2015 NIAID 5R21AI111696-02 Targeting a New Essential Virulence Mechanism in Drug-Resistant Mycobacteria STALLINGS, CHRISTINA WASHINGTON UNIVERSITY MO $204,221
Orphan Drug 2015 NIAID 5R43AI112097-02 Optimization of Arenavirus Antivirals PLEWE, MICHAEL ARISAN THERAPEUTICS, INC. CA $300,000
Orphan Drug 2015 NINDS 5R01NS073762-05 The role of mTORC1 in the development and therapeutic targeting of NF1-associated ZHU, YUAN CHILDREN'S RESEARCH INSTITUTE DC $376,250
Orphan Drug 2015 NIAID 5R21AI106779-02 BCG efficacy against W-Beijing TB strains ORME, IAN COLORADO STATE UNIVERSITY CO $223,050
Orphan Drug 2015 NIAID 5R21AI111647-02 Discovery and validation of drug targets in vulnerable pathways of Mtb ALLAND, DAVID RBHS-NEW JERSEY MEDICAL SCHOOL NJ $218,623
Orphan Drug 2015 NHLBI 5R01HL108962-05 Gene-by-Gene Interactions and Lung Fluid Balance in Patients with Heart Failure SNYDER, ERIC UNIVERSITY OF MINNESOTA MN $442,422
Orphan Drug 2015 NINDS 1U01NS090284-01 Human EGFRvIII-specific BiTE for the treatment of Glioblastoma SAMPSON, JOHN DUKE UNIVERSITY NC $569,842
Orphan Drug 2015 NCI 2P30CA014236-41 5328 Neuro-Oncology Research Program KASTAN, MICHAEL DUKE UNIVERSITY NC $64,644
Orphan Drug 2015 NCI 2P30CA014236-41 5329 Women's Cancer Research Program KASTAN, MICHAEL DUKE UNIVERSITY NC $57,641
Orphan Drug 2015 NCI 2P30CA014236-41 5330 Hematologic Malignancies and Cellular Therapies Research Program KASTAN, MICHAEL DUKE UNIVERSITY NC $64,644
Orphan Drug 2015 NCI 2P30CA014236-41 5331 Solid Tumor Therapeutics Research Program KASTAN, MICHAEL DUKE UNIVERSITY NC $64,644
Orphan Drug 2015 NIAID 5R01AI094973-05 A large-scale transposon mutagenesis screen of Plasmodium falciparum ADAMS, JOHN UNIVERSITY OF SOUTH FLORIDA FL $367,500
Orphan Drug 2015 NIAID 5R21AI111667-02 Targeting SecA1 of Mycobacterium tuberculosis for Novel Drug Development BRAUNSTEIN, MIRIAM UNIV OF NORTH CAROLINA CHAPEL HILL NC $230,399
Orphan Drug 2015 NINDS 5R21NS083831-02 Small chemical modulators of SMN biology as candidate therapeutics for SMA PELLIZZONI, LIVIO COLUMBIA UNIVERSITY HEALTH SCIENCES NY $320,000
Orphan Drug 2015 NINDS 5R24NS086554-02 Establishment of a Human Grade IV Glioma Stem Cell Line Bank REYNOLDS, BRENT UNIVERSITY OF FLORIDA FL $242,306
Orphan Drug 2015 NCI 2P01CA084203-11A1 5338 Project 2: Endoscopic Photodynamic and Combination Therapy for Local and Metastatic Pancreatic Tumors PEREIRA, STEPHEN MASSACHUSETTS GENERAL HOSPITAL MA $215,923
Orphan Drug 2015 NCI 2P01CA084203-11A1 5339 Project 3: Mechanism-Based Design ofCombination Therapies for Pancreatic Cancer HASAN, TAYYABA MASSACHUSETTS GENERAL HOSPITAL MA $234,824
Orphan Drug 2015 NIGMS 1K99GM112877-01 Understanding Epstein Barr virus oncogenicity through non-coding RNA structure MOSS, WALTER YALE UNIVERSITY CT $90,000
Orphan Drug 2015 NIAID 5R37AI048793-15 Immunogenetic Mechanisms of Vaccine Response POLAND, GREGORY MAYO CLINIC ROCHESTER MN $451,817
Orphan Drug 2015 NIAID 5K08AI097239-04 Deciphering apicoplast function during blood stage Plasmodium infection YEH, ELLEN STANFORD UNIVERSITY CA $133,191
Orphan Drug 2015 NCI 5R21CA182926-02 Characterization of non-competitive proteasome binding TEPE, JETZE MICHIGAN STATE UNIVERSITY MI $156,119
Orphan Drug 2015 NCI 5U01CA183030-02 Therapeutic Elimination of Stem Cells for Relapsed Pediatric AML LIU, YANG CHILDREN'S RESEARCH INSTITUTE DC $628,352
Orphan Drug 2015 NHLBI 1K99HL125728-01 Development of Zr-89 based ImmunoPET agents for Idiopathic Pulmonary Fibrosis BOROS, ESZTER MASSACHUSETTS GENERAL HOSPITAL MA $137,080
Orphan Drug 2015 NCI 2P30CA015704-40 5445 Research Program: Gastrointestinal Cancer GRADY, WILLIAM FRED HUTCHINSON CANCER RESEARCH CENTER WA $89,613
Orphan Drug 2015 NIAID 5U19AI109680-02 7495 Identification and Development of Anti-Flavivirus Lead Drug Candidates NELSON, JAY OREGON HEALTH & SCIENCE UNIVERSITY OR $780,709
Orphan Drug 2015 NIAID 5U19AI109680-02 7500 Screening Core BOSTWICK, JAMES SOUTHERN RESEARCH INSTITUTE AL $1,313,870
Orphan Drug 2015 NINDS 5R01NS082788-02 A novel role for a bicistronic calcium channel gene in neurodevelopment and neuro GOMEZ, CHRISTOPHER UNIVERSITY OF CHICAGO IL $439,859
Orphan Drug 2015 NEI 1K99EY024992-01 Drug discovery and mechanistic study of P23H rhodopsin associated retinitis pigmentosa CHEN, YUANYUAN CASE WESTERN RESERVE UNIVERSITY OH $96,390
Orphan Drug 2015 NIAID 5R01AI104960-02 Application of Imaging to Development of Tuberculosis Interventions CIRILLO, JEFFREY TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR TX $371,800
Orphan Drug 2015 NIAID 5R21AI109068-02 The role of the C1P/cPLA2alpha interaction in anaphylaxis CHALFANT, CHARLES VIRGINIA COMMONWEALTH UNIVERSITY VA $190,625
Orphan Drug 2015 NCI 5P01CA117969-10 8697 FUNCTIONAL GENOMIC IDENTIFICATION AND CHARACTERIZATION OF THERAPEUTIC TARGETS DEPINHO, RONALD UNIVERSITY OF TX MD ANDERSON CAN CTR TX $483,631
Orphan Drug 2015 NIAID 5U19AI109725-02 8415 Autophagy-Inducting Peptides and Target Identification for Treatment of Viruses LEVINE, BETH WASHINGTON UNIVERSITY MO $1,703,120
Orphan Drug 2015 NIAID 5R43AI112165-02 Automating mosquito microdissection for a malaria PfSPZ vaccine HOFFMAN, STEPHEN SANARIA, INC. MD $299,999
Orphan Drug 2015 NIAMS 5R01AR044345-17 Genes and Therapies for Centronuclear Myopathies BEGGS, ALAN CHILDREN'S HOSPITAL CORPORATION MA $369,750
Orphan Drug 2015 NINDS 5R21NS087467-02 Modulation of FcRn: A strategy to prevent autoantibody-mediated nerve injury SHEIKH, KAZIM UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON TX $190,000
Orphan Drug 2015 NIAID 1R21AI115358-01 Antigen metabolomics for mucosal-associated invariant T cells in tuberculosis HUANG, SHOUXIONG UNIVERSITY OF CINCINNATI OH $277,011
Orphan Drug 2015 NCI 1R21CA191631-01 Dual recombinase models of pancreatic cancer SEELEY, ELLIOTT UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $206,516
Orphan Drug 2015 NCI 1R21CA191392-01 Identifying new drug targets to block K-Ras/Raf in pancreatic cancer. STORK, PHILIP OREGON HEALTH & SCIENCE UNIVERSITY OR $200,970
Orphan Drug 2015 NHLBI 5K08HL107142-05 Chloride secretagogues for acquired CFTR dysfunction in chronic rhinosinusitis WOODWORTH, BRADFORD UNIVERSITY OF ALABAMA AT BIRMINGHAM AL $133,596
Orphan Drug 2015 NCI 5R21CA182662-02 Elucidating and targeting epigenetic oncogenic networks in pancreatic cancer TZATSOS, ALEXANDROS GEORGE WASHINGTON UNIVERSITY DC $206,843
Orphan Drug 2015 NCI 5R21CA185370-02 Conferring in vivo metabolic resistance to a highly selective anti-AML agent MERINO, EDWARD UNIVERSITY OF CINCINNATI OH $159,949
Orphan Drug 2015 NCI 1R21CA183623-01A1 Pediatric Cancer Salvia Biorepository PENNO, MARGARET JOHNS HOPKINS UNIVERSITY MD $220,359
Orphan Drug 2015 NCI 1R03CA191621-01 Developing a Screen for Novel Therapies with Reprogrammed Pancreatic Cancer Cells RESAR, LINDA JOHNS HOPKINS UNIVERSITY MD $81,000
Orphan Drug 2015 NCI 1R21CA191515-01 New transgenic animal model to study pancreatic cancer FISHER, PAUL VIRGINIA COMMONWEALTH UNIVERSITY VA $213,881
Orphan Drug 2015 NIAID 5R01AI009644-46 Biochemistry of Bacterial Cell Membranes NIKAIDO, HIROSHI UNIVERSITY OF CALIFORNIA BERKELEY CA $667,403
Orphan Drug 2015 NINDS 5R01NS089449-02 THE ROLE OF BK CHANNELS IN NEUROPATHOLOGY OF FRAGILE X SYNDROME KLYACHKO, VITALY WASHINGTON UNIVERSITY MO $380,000
Orphan Drug 2015 NIAID 1R21AI115383-01 Newcastle Disease Virus Vectored Vaccine against Poliomyelitis BELOV, GEORGIY UNIV OF MARYLAND, COLLEGE PARK MD $190,000
Orphan Drug 2015 NIAID 1R21AI115451-01 Synthetic neoglycopeptides as Chagas disease vaccine ALMEIDA, IGOR UNIVERSITY OF TEXAS EL PASO TX $198,860
Orphan Drug 2015 NIAID 1R21AI115534-01 Anaphylaxis and IgE heterogeneity KAWAKAMI, TOSHIAKI LA JOLLA INST FOR ALLERGY & IMMUNOLGY CA $273,475
Orphan Drug 2015 NIAID 5R24AI100646-04 Consortium for TB Biomarkers MENDEL, CARL GLOBAL ALLIANCE FOR TB DRUG DEVELOPMENT NY $446,946
Orphan Drug 2015 NIAID 5U19AI109740-02 8497 Small-molecule inhibitors of flavivirus entry YANG, PRISCILLA HARVARD MEDICAL SCHOOL MA $1,128,723
Orphan Drug 2015 NIAID 5R21AI111168-02 Minipigs as animal model for infant TB and vaccine efficacy GONZALEZ-JUARRERO, MERCEDES COLORADO STATE UNIVERSITY CO $185,875
Orphan Drug 2015 NCI 5R01CA166711-03 Purine Synthesis Inhibitors with Selective Folate Receptor Tumor Transport GANGJEE, ALEEM DUQUESNE UNIVERSITY PA $558,208
Orphan Drug 2015 NCI 5R01CA184274-02 Functional Significance of CD133 in Pancreatic Cancer BANERJEE, SULAGNA UNIVERSITY OF MINNESOTA MN $315,400
Orphan Drug 2015 NIAID 5R01AI099188-04 Chemical probes of vulnerable pathways in antibiotic-resistant pathogens PARISH, TANYA INFECTIOUS DISEASE RESEARCH INSTITUTE WA $744,764
Orphan Drug 2015 NIAID 5R01AI109644-02 Differential mechanisms for RORgammat-regulated thymocyte development and Th17 di SUN, ZUOMING CITY OF HOPE/BECKMAN RESEARCH INSTITUTE CA $420,000
Orphan Drug 2015 NIAID 5F31AI094961-05 Protective Effects of Anti-BclA Antibodies in Bacillus anthracis Infection RODRIGUEZ BARRANTES, JUAN UNIVERSITY OF ALABAMA AT BIRMINGHAM AL $34,982
Orphan Drug 2015 NCI 5R21CA185712-02 3D-Microtumor_GBM Xenoline Proband Modeling of Kinome-Directed Therapy WILLEY, CHRISTOPHER UNIVERSITY OF ALABAMA AT BIRMINGHAM AL $159,863
Orphan Drug 2015 NHLBI 5R01HL113006-04 Human Induced Pluripotent Stem Cells for Cardiovascular Disease Modeling WU, JOSEPH STANFORD UNIVERSITY CA $387,104
Orphan Drug 2015 NHLBI 5R00HL111345-05 Model of Timothy Syndrome to Screen Drugs with Induced Pluripotent Stem Cells YAZAWA, MASAYUKI COLUMBIA UNIVERSITY HEALTH SCIENCES NY $244,021
Orphan Drug 2015 NINDS 5R01NS075075-04 Determinants of Neurodegenerative Decline in Primary Progressive Aphasia ROGALSKI, EMILY NORTHWESTERN UNIVERSITY AT CHICAGO IL $338,674
Orphan Drug 2015 NIAID 1R15AI111210-01A1 Decoding P. aeruginosa RIP cascade and discovering its inhibitors as therapeutics MATHEE, KALAI FLORIDA INTERNATIONAL UNIVERSITY FL $421,190
Orphan Drug 2015 NCI 1R15CA192160-01 Multifunctional nanoparticles for combinational therapy of pancreatic cancer VIVERO-ESCOTO, JUAN UNIVERSITY OF NORTH CAROLINA CHARLOTTE NC $437,210
Orphan Drug 2015 NIAID 5R01AI099204-04 Chemical Inhibitors to Define an Essential M. Tuberculosis Signaling Network HUSSON, ROBERT CHILDREN'S HOSPITAL CORPORATION MA $1,214,907
Orphan Drug 2015 NIAMS 5R03AR065142-02 Mechanisms of Vertebral Bone Disease in Mucopolysaccharidosis VII SMITH, LACHLAN UNIVERSITY OF PENNSYLVANIA PA $80,000
Orphan Drug 2015 NIDDK 5K08DK090145-05 Novel therapeutic targets for Diamond Blackfan anemia and other ribosomopathies NARLA, ANUPAMA STANFORD UNIVERSITY CA $152,874
Orphan Drug 2015 NIGMS 5R01GM061851-12 Targeted Drug Delivery to Surface Receptors. SZOKA, FRANCIS UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $298,567
Orphan Drug 2015 NHLBI 5R01HL108213-04 VEGF receptor-1-mediated protection in dilated cardiomyopathy RECCHIA, FABIO TEMPLE UNIV OF THE COMMONWEALTH PA $398,687
Orphan Drug 2015 NIAID 5U19AI109755-02 8165 Genetic determinants of drug resistance in Mycobacteria tuberculosis MURRAY, MEGAN HARVARD SCHOOL OF PUBLIC HEALTH MA $500,331
Orphan Drug 2015 NCI 5K08CA181340-02 Targeting Chromatin Modifications in Leukemia with Trisomy 21 LANE, ANDREW DANA-FARBER CANCER INST MA $155,991
Orphan Drug 2015 NCI 1R21CA191679-01 Development of Nuclear Auger Emitters for Targeted Radiotherapy REINER, THOMAS SLOAN-KETTERING INST CAN RESEARCH NY $101,904
Orphan Drug 2015 NCI 1R21CA191687-01 Genetic Predictors of Response to mTOR inhibitors in advanced Renal Cancer CHOUEIRI, TONI DANA-FARBER CANCER INST MA $229,296
Orphan Drug 2015 NCI 1R21CA191726-01 Therapeutic targeting of the B-cell lymphoma associated mutation MYD88-L265P SNYDER, GREG UNIVERSITY OF MARYLAND BALTIMORE MD $215,284
Orphan Drug 2015 NCI 1R03CA184394-01A1 Intraperitoneal Delivery of Targeted Nanoparticles for Metastatic Ovarian Cancer LU, XIULING UNIVERSITY OF CONNECTICUT STORRS CT $79,000
Orphan Drug 2015 NCI 1R21CA191751-01 Repositioning Bazedoxifene as a novel IL-6/GP130 inhibitor for sarcoma therapy LIN, JIAYUH RESEARCH INST NATIONWIDE CHILDREN'S HOSP OH $175,974
Orphan Drug 2015 NIAID 5R01AI094458-05 Development of a New Diamine (SQ109) for the Treatment of C. difficile Infection PROTOPOPOVA, MARINA SEQUELLA, INC. MD $728,339
Orphan Drug 2015 NIAID 5R01AI104817-03 HOST AND MICROBIOLOGICAL DETERMINANTS OF INFECTIOUSNESS IN PATIENTS WITH DRUG SEN DHEDA, KEERTAN UNIVERSITY OF CAPE TOWN SO AFR $135,000
Orphan Drug 2015 NHLBI 5P01HL010342-47 7526 Regulation of pulmonary fibrosis by CD4+T cells MITZNER, WAYNE JOHNS HOPKINS UNIVERSITY MD $417,795
Orphan Drug 2015 NHLBI 5R01HL108248-06 Single molecule measurements on von Willebrand factor A1 and A2 domains SPRINGER, TIMOTHY CHILDREN'S HOSPITAL CORPORATION MA $459,472
Orphan Drug 2015 NCI 1R01CA177810-01A1 Modulation of MicroRNAs with Xenobiotics to Target c-Myc LI, YONG CLEVELAND CLINIC LERNER COM-CWRU OH $383,141
Orphan Drug 2015 NCI 1R21CA191898-01 Novel therapeutic strategies targeting conformational plasticity of type I MAGE CHO, HEARN ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI NY $223,096
Orphan Drug 2015 NCI 1R21CA191929-01 Establish RPN 13-Proteasome Association as a Novel Anticancer Target HILL, CHRISTOPHER UNIVERSITY OF UTAH UT $194,445
Orphan Drug 2015 NCI 1R21CA186004-01A1 Immunotherapeutic targeting of the Glioblastoma Mutanome PRINS, ROBERT UNIVERSITY OF CALIFORNIA LOS ANGELES CA $180,105
Orphan Drug 2015 NCI 5K23CA154874-03 Optimization of adoptive immunotherapy with autologous CD20-specific T cells TILL, BRIAN FRED HUTCHINSON CANCER RESEARCH CENTER WA $171,720
Orphan Drug 2015 NCI 5R01CA160593-03 Survival Bump Hunting for Finding Informative Subgroups in High Dimensional Data. RAO, J UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $260,014
Orphan Drug 2015 NCATS 5R13AI094943-05 Primary Immune Deficiency Treatment Consortium Annual Scientific Meeting COWAN, MORTON UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $9,000
Orphan Drug 2015 NIAID 5R13AI094943-05 Primary Immune Deficiency Treatment Consortium Annual Scientific Meeting COWAN, MORTON UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $9,000
Orphan Drug 2015 NCI 5R01CA135332-05 Validation of microRNAs as therapeutic targets in hematological malignancies MUTHUSAMY, NATARAJAN OHIO STATE UNIVERSITY OH $316,438
Orphan Drug 2015 NCI 5K99CA181496-02 Modeling p53 Mutant-Associated Cancer With LFS Patient-Derived iPSCs LEE, DUNG-FANG ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI NY $101,520
Orphan Drug 2015 NHLBI 5UM1HL113460-04 Cell Based Therapy for Non-Ischemic Dilated Cardiomyopathy HARE, JOSHUA UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $574,293
Orphan Drug 2015 NCI 1R01CA175318-01A1 A Nanotechnology Platform for Suicide Gene Therapy of Recurring Ovarian Cancer HATEFI, ARASH RUTGERS, THE STATE UNIV OF N.J. NJ $354,563
Orphan Drug 2015 NCI 5R13CA086959-15 The Annual Blood-Brain Barrier Consortium Meeting NEUWELT, EDWARD OREGON HEALTH & SCIENCE UNIVERSITY OR $10,000
Orphan Drug 2015 NIDCD 5R13CA086959-15 The Annual Blood-Brain Barrier Consortium Meeting NEUWELT, EDWARD OREGON HEALTH & SCIENCE UNIVERSITY OR $5,000
Orphan Drug 2015 NINDS 5R13CA086959-15 The Annual Blood-Brain Barrier Consortium Meeting NEUWELT, EDWARD OREGON HEALTH & SCIENCE UNIVERSITY OR $10,000
Orphan Drug 2015 NCI 5R01CA162401-03 Improving Adherence to Oral Cancer Agents and Self Care of Symptoms Using an IVR GIVEN, BARBARA MICHIGAN STATE UNIVERSITY MI $613,585
Orphan Drug 2015 NCI 5R01CA169158-03 Dopamine as a therapeutic agent in stomach cancer BASU, SUJIT OHIO STATE UNIVERSITY OH $319,550
Orphan Drug 2015 NHLBI 5R01HL109209-04 Whole genome DNA sequencing to identify novel genes in dilated cardiomyopathy TAYLOR, MATTHEW UNIVERSITY OF COLORADO DENVER CO $429,571
Orphan Drug 2015 NCI 1R01CA184051-01A1 Pharmacological Ascorbate as a Radiosensitizer in Pancreatic Cancer CULLEN, JOSEPH UNIVERSITY OF IOWA IA $345,413
Orphan Drug 2015 NIAID 2R01AI075045-06 Resistance of Malaria Parasites to Artemisinin-Based Therapies ROSENTHAL, PHILIP UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $575,561
Orphan Drug 2015 NCI 5F31CA183531-02 Targeting Gain-of-Function p53 Missense Mutants SHAVER, TIMOTHY VANDERBILT UNIVERSITY TN $27,772
Orphan Drug 2015 NIAID 5R01AI036525-17 Immune Mechanisms of Protection in S. Typhi Vaccines SZTEIN, MARCELO UNIVERSITY OF MARYLAND BALTIMORE MD $469,830
Orphan Drug 2015 NCI 5R01CA149109-05 The role of microRNAs in leukemic initiation and maintenance LU, JUN YALE UNIVERSITY CT $345,488
Orphan Drug 2015 NCI 5R01CA169200-03 The FGF18/FGFR4 amplicon: Novel therapeutic biomarkers for ovarian cancer BIRRER, MICHAEL MASSACHUSETTS GENERAL HOSPITAL MA $372,052
Orphan Drug 2015 NEI 1R01EY024249-01A1 A High Content Screening Approach for the Retinal Degenerative Diseases BERLINICKE, CYNTHIA JOHNS HOPKINS UNIVERSITY MD $405,000
Orphan Drug 2015 NCI 1R01CA179072-01A1 Therapeutically Exploiting a Newly Isolated Neural-like Stem Cell Against GBM MINTZ, AKIVA WAKE FOREST UNIVERSITY HEALTH SCIENCES NC $325,246
Orphan Drug 2015 NCI 1R01CA184088-01A1 Liposomal Doxorubicin and Pluronic Combination for Cancer Therapy KABANOV, ALEXANDER UNIV OF NORTH CAROLINA CHAPEL HILL NC $344,549
Orphan Drug 2015 NIGMS 1R01GM107465-01A1 Molecular principles of translation termination KOROSTELEV, ANDREI UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $322,438
Orphan Drug 2015 NEI 2R01EY013433-08 A Ribozyme Rescue Strategy for Autosomal Dominant Retinitis Pigmentosa SULLIVAN, JOHN STATE UNIVERSITY OF NEW YORK AT BUFFALO NY $378,000
Orphan Drug 2015 NCI 1R01CA181658-01A1 MRI-Monitored Delivery of Sorafenib-Eluting Microspheres to Liver Tumors LARSON, ANDREW NORTHWESTERN UNIVERSITY AT CHICAGO IL $324,238
Orphan Drug 2015 NIAID 5R01AI060899-12 Bacterial N-Acetyltransferases: Resistance to Regulation BLANCHARD, JOHN ALBERT EINSTEIN COLLEGE OF MEDICINE NY $196,188
Orphan Drug 2015 NIAID 5R01AI093666-05 A novel single dose vaccine for pre-and post-exposure prophylaxis of rabies FABER, MILOSZ THOMAS JEFFERSON UNIVERSITY PA $387,500
Orphan Drug 2015 NIAID 5R01AI111962-02 Optimized Combination Antimalarial Drug Therapy ROEPE, PAUL GEORGETOWN UNIVERSITY DC $923,203
Orphan Drug 2015 RMAP 5R01AI111962-02 Optimized Combination Antimalarial Drug Therapy ROEPE, PAUL GEORGETOWN UNIVERSITY DC $163,987
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