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RCDC

Project Listing by Category


Back to Estimates of Funding for Various Research, Condition, and Disease Categories (RCDC) Click the column headings to sort project listings.
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CategoryFYFunding ICProject NumberSub Project #Project TitlePI NameOrg NameState / CountryAmount
ALS 2015 NIEHS 5R01ES022310-03 Association of ALS to gene-environment mediated changes in HDL proteins SIDDIQUE, TEEPU NORTHWESTERN UNIVERSITY AT CHICAGO IL $621,473
ALS 2015 NIDCD 5R21DC013095-02 Prosody in Congenital and Acquired Dysarthria. PATEL, RUPAL NORTHEASTERN UNIVERSITY MA $215,373
ALS 2015 NINDS 5R01NS073829-04 Study on Neurodegeneration Using TDP-43 Transgenic Rats ZHOU, HONGXIA THOMAS JEFFERSON UNIVERSITY PA $339,063
ALS 2015 NIDCD 5R01DC013547-02 SPEECH MOVEMENT CLASSIFICATION FOR ASSESSING AND TREATING ALS GREEN, JORDAN MGH INSTITUTE OF HEALTH PROFESSIONS MA $584,132
ALS 2015 NINDS 5R01NS057553-09 Animal Models for Studying Human Frontotemporal Dementia GAO, FEN-BIAO UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $366,406
ALS 2015 NINDS 5R01NS052325-10 Trophic Factor Signaling and Motor Neuron Death KALB, ROBERT CHILDREN'S HOSP OF PHILADELPHIA PA $366,406
ALS 2015 NINDS 5R01NS074886-05 Role of ABC efflux transporters in ALS TROTTI, DAVIDE THOMAS JEFFERSON UNIVERSITY PA $339,063
ALS 2015 NINDS 5R01NS040433-13 Immune Regulation of Neuronal Injury and Repair JONES, KATHRYN INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS IN $524,000
ALS 2015 NINDS 5R01NS078504-04 Disease Mechanisms in Human Ubiquilinopathy SIDDIQUE, TEEPU NORTHWESTERN UNIVERSITY AT CHICAGO IL $502,357
ALS 2015 NINDS 5R44NS076194-04 Preclinical testing of the splice modulating oligonucleotide LSP-GR1 LUTZ, GORDON LIFESPLICE PHARMA, LLC PA $1,033,937
ALS 2015 NIEHS 5R01ES020395-04 Stress Granules and the Biology of TDP-43 WOLOZIN, BENJAMIN BOSTON UNIVERSITY MEDICAL CAMPUS MA $969,140
ALS 2015 NINDS 5R01NS065317-07 Molecular Basis of TDP-43 Proteinopathies: Disease Models and Mechanisms GITLER, AARON STANFORD UNIVERSITY CA $350,391
ALS 2015 NINDS 5R01NS078398-04 DEVELOPING A MICRORNA-TARGETED THERAPY FOR ALS MILLER, TIMOTHY WASHINGTON UNIVERSITY MO $332,500
ALS 2015 NIGMS 5R01GM069909-12 Structures and mechanisms of nuclear import and export CHOOK, YUH MIN UT SOUTHWESTERN MEDICAL CENTER TX $333,488
ALS 2015 NINDS 5R21NS087351-02 C9ORF72 Genetically Engineered Mice LUTZ, CATHLEEN JACKSON LABORATORY ME $218,750
ALS 2015 NINDS 5R37NS060698-07 Mechanistic analysis of axonal transport defects in neurodegenerative disease HOLZBAUR, ERIKA UNIVERSITY OF PENNSYLVANIA PA $385,720
ALS 2015 NIA 1K01AG049152-01 RNA signatures of frontotemporal dementia and ALS due to C9ORF72 expansion YOKOYAMA, JENNIFER UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $129,396
ALS 2015 NINDS 5R03NS087290-02 Exploring a role for LINE1 retrotransposons in neurodegenerative disease GOODIER, JOHN JOHNS HOPKINS UNIVERSITY MD $81,000
ALS 2015 NINDS 5R01NS078145-04 Investigating a Toxic Gain-of-Interaction Between FUS/TLS & Stress Granules BOSCO, DARYL UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $359,844
ALS 2015 NIA 5K99AG047335-02 The Role of Cortical Projection Neurons Susceptible to Progressive Degeneration w MAROOF, ASIF HARVARD UNIVERSITY MA $88,506
ALS 2015 NINDS 5R01NS084089-03 Mechanisms of Neurodegeneration in ALS XIA, XUGANG THOMAS JEFFERSON UNIVERSITY PA $339,063
ALS 2015 NIGMS 5R01GM080742-09 Protein misfolding and aggregation DOKHOLYAN, NIKOLAY UNIV OF NORTH CAROLINA CHAPEL HILL NC $332,719
ALS 2015 NINDS 5K08NS082364-02 Defining an Electrophysiological Phenotype of ALS Patient-Derived Motor Neurons WAINGER, BRIAN MASSACHUSETTS GENERAL HOSPITAL MA $193,536
ALS 2015 NINDS 5R01NS074324-05 Neurodegeneration and Proteotoxicity Dissected in C. elegans and Mammals WANG, JIOU JOHNS HOPKINS UNIVERSITY MD $322,875
ALS 2015 NIA 5P50AG005131-32 5888 Project 2: Disease Mechanisms in Frontotemporal Dementia Linked to C9orf72 Expans LAGIER-TOURENNE, CLOTILDE UNIVERSITY OF CALIFORNIA SAN DIEGO CA $180,577
ALS 2015 NINDS 5R01NS079836-04 High Throughput Screening for Compounds to Mitigate Toxicity of FUS/TLS & SOD1 BROWN, ROBERT UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $430,747
ALS 2015 NINDS 5K08NS082365-02 The Role of Sirtuin 1 Deacetylase in Amyotrophic Lateral Sclerosis HERSKOVITS, ADRIANNA BRIGHAM AND WOMEN'S HOSPITAL MA $192,510
ALS 2015 NINDS 5R01NS072428-03 Role of MMP-9 in selective motor neuron degeneration in ALS PRZEDBORSKI, SERGE COLUMBIA UNIVERSITY HEALTH SCIENCES NY $329,585
ALS 2015 NINDS 5R01NS082304-02 Development of a Multi-Modal Neuroimaging Biomarker for Amyotrophic Lateral Scler WELSH, ROBERT UNIVERSITY OF MICHIGAN MI $577,490
ALS 2015 NINDS 5R01NS081303-03 Cellular and Molecular Mechanisms of FUS-related Amyotrophic Lateral Sclerosis PANDEY, UDAI UNIVERSITY OF PITTSBURGH AT PITTSBURGH PA $345,366
ALS 2015 NINDS 5K01NS069616-05 A New Approach to ALS MITCHELL, CASSIE GEORGIA INSTITUTE OF TECHNOLOGY GA $128,293
ALS 2015 NINDS 5R01NS076471-03 Molecular genetic studies of progranulin regulators in FTLD and ALS RADEMAKERS, ROSA MAYO CLINIC JACKSONVILLE FL $342,344
ALS 2015 NINDS 5R03NS088940-02 RNA lariat debranching enzyme as a novel drug target MENEES, THOMAS UNIVERSITY OF MISSOURI KANSAS CITY MO $75,500
ALS 2015 NINDS 5R01NS088578-02 Developing ASO Therapy for Repeat Expanded C9orf72 ALS-FTD RAVITS, JOHN UNIVERSITY OF CALIFORNIA SAN DIEGO CA $428,588
ALS 2015 NINDS 5R01NS027036-28 Neurofilaments, SOD1 and Motor Neuron Diseases CLEVELAND, DON LUDWIG INSTITUTE FOR CANCER RES LTD CA $492,551
ALS 2015 NINDS 1R01NS090962-01 Re-Establishing Vascular Integrity in ALS via Endothelial Cell Transplant GARBUZOVA-DAVIS, SVITLANA UNIVERSITY OF SOUTH FLORIDA FL $327,031
ALS 2015 NINDS 5R01NS078214-04 Active zone loss cause dying back neuropathy in amyotrophic lateral sclerosis NISHIMUNE, HIROSHI UNIVERSITY OF KANSAS MEDICAL CENTER KS $330,313
ALS 2015 NINDS 5R01NS073660-05 Ataxin-2 as a genetic risk factor for ALS: New insights into neurodegeneration BONINI, NANCY UNIVERSITY OF PENNSYLVANIA PA $341,510
ALS 2015 NINDS 5R01NS088689-02 Silencing C9or72 with rAAV Mediated RNAi BROWN, ROBERT UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $360,494
ALS 2015 NINDS 5R01NS073776-05 FUS/TLS GAIN AND LOSS OF FUNCTION IN ALS: ANIMAL AND CELLULAR MODELS OF DISEASE SHNEIDER, NEIL COLUMBIA UNIVERSITY HEALTH SCIENCES NY $350,000
ALS 2015 NIA 5P01AG019724-14 5685 Clinical and Administrative MILLER, BRUCE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $541,414
ALS 2015 NIA 5P01AG019724-14 5694 Clinical Criteria MILLER, BRUCE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CA $248,751
ALS 2015 NIGMS 5R01GM046295-20 Mechanisms and functions of subcellular motility SAXTON, WILLIAM UNIVERSITY OF CALIFORNIA SANTA CRUZ CA $307,031
ALS 2015 NINDS 5R01NS044292-12 Impairment of the glial glutamate transporter GLT1 in ALS TROTTI, DAVIDE THOMAS JEFFERSON UNIVERSITY PA $339,063
ALS 2015 NINDS 5R01NS064131-07 Developing neuroprotective strategies for proteinopathy KRAEMER, BRIAN SEATTLE INST FOR BIOMEDICAL/CLINICAL RES WA $295,313
ALS 2015 NINDS 5R01NS045893-10 Prospective study of biomarkers and risk factors for ALS incidence and progressio ASCHERIO, ALBERTO HARVARD SCHOOL OF PUBLIC HEALTH MA $451,678
ALS 2015 NINDS 5R00NS080985-04 TDP-43 acetylation as a pathogenic modification in ALS & related proteinopathies COHEN, TODD UNIV OF NORTH CAROLINA CHAPEL HILL NC $243,641
ALS 2015 NINDS 1R01NS091540-01 Muscle stem cells: New ALS growth factor therapy and disease model SUZUKI, MASATOSHI UNIVERSITY OF WISCONSIN-MADISON WI $334,688
ALS 2015 NINDS 1R01NS091836-01 Mechanisms Underlying Excitability Regulation of Motoneuron Types in ALS ELBASIOUNY, SHERIF WRIGHT STATE UNIVERSITY OH $323,750
ALS 2015 NINDS 1K22NS091314-01 Epigenetics In Neurodegenerative Disease: Targeting Histone Modifications in ALS TORRENTE, MARIANA UNIVERSITY OF PENNSYLVANIA PA $55,143
ALS 2015 NINDS 1K99NS091538-01 Mechanisms of C9orf72 hexanucleotide repeat expansion caused neurodegeneration in ALS and FTD SUN, SHUYING LUDWIG INSTITUTE FOR CANCER RES LTD CA $93,042
ALS 2015 NINDS 1R21NS091630-01 Statistical Methods for Causal Inference in Observational Studies LONG, QI EMORY UNIVERSITY GA $193,729
ALS 2015 NINDS 5K08NS072233-06 Elucidating the Mechanisms Underlying Mutant TDP43-induced Neurodegeneration BARMADA, SAMI UNIVERSITY OF MICHIGAN MI $175,448
ALS 2015 NINDS 5F32NS089290-02 The PERKplexity of the integrated stress response in motor neurons and myelinatin DZHASHIASHVILI, YULIA UNIVERSITY OF CHICAGO IL $59,966
ALS 2015 NIDCD 1R01DC014034-01A1 Advanced neural decoders for the restoration of communication HENDERSON, JAIMIE STANFORD UNIVERSITY CA $805,287
ALS 2015 NIEHS 5R44ES022103-03 CyanoMap: Mapping inland lake quality and Amyotrophic lateral sclerosis risk fact TORBICK, NATHAN APPLIED GEOSOLUTIONS, LLC NH $460,063
ALS 2015 NINDS 5F31NS089131-02 Role of p62 in Amyotrophic Lateral Sclerosis RUDNICK, NOAM COLUMBIA UNIVERSITY HEALTH SCIENCES NY $43,887
ALS 2015 NIGMS 5R01GM048259-29 Mechanisms of alternative splicing of pre-mRNA MANLEY, JAMES COLUMBIA UNIV NEW YORK MORNINGSIDE NY $513,033
ALS 2015 NINDS 5K23NS083715-02 Molecular Imaging of Inflammation in Amyotrophic Lateral Sclerosis (ALS) ATASSI, NAZEM MASSACHUSETTS GENERAL HOSPITAL MA $194,616
ALS 2015 NINDS 1R21NS088839-01A1 Seeded transmission of SOD1 misfolding BORCHELT, DAVID UNIVERSITY OF FLORIDA FL $225,000
ALS 2015 NINDS 5K08NS075094-05 NEXT-GENERATION SEQUENCING APPROACHES FOR NOVEL GENE DISCOVERY IN ALS HARMS, MATTHEW WASHINGTON UNIVERSITY MO $157,414
ALS 2015 NINDS 5R01NS080882-04 GGGGCC hexanucleotide repeat expansions in neurodegenerative disease RADEMAKERS, ROSA MAYO CLINIC JACKSONVILLE FL $364,067
ALS 2015 NINDS 5F32NS084667-03 Epigenetic mechanisms of TDP43-mediated neurodegeneration BERSON, AMIT UNIVERSITY OF PENNSYLVANIA PA $56,042
ALS 2015 NINDS 5K01NS085071-03 Role of Target-derived FGFs in Maintaining and Repairing Synapses VALDEZ, GREGORIO VIRGINIA POLYTECHNIC INST AND ST UNIV VA $226,356
ALS 2015 NINDS 5R21NS082618-02 High-Throughput Modeling of ALS Using iPSC-Derived Neural Tube Microarrays ASHTON, RANDOLPH UNIVERSITY OF WISCONSIN-MADISON WI $174,211
ALS 2015 NINDS 5R01NS077982-04 Phase 1b Trial of stem cells in ALS GLASS, JONATHAN EMORY UNIVERSITY GA $709,886
ALS 2015 NINDS 1R01NS089640-01A1 NAD metabolsim and mitochondrial dysfunction in ALS models VARGAS, MARCELO MEDICAL UNIVERSITY OF SOUTH CAROLINA SC $320,188
ALS 2015 NIDCD 1F32DC014382-01A1 Innovative Biomarkers of Orofacial Dysfunction in Amyotrophic Lateral Sclerosis MCILDUFF, COURTNEY BETH ISRAEL DEACONESS MEDICAL CENTER MA $62,066
ALS 2015 NINDS 5R01NS089701-02 Redesign Rat Model for ALS Research ZHOU, HONGXIA THOMAS JEFFERSON UNIVERSITY PA $341,068
ALS 2015 NIEHS 1R01ES024064-01A1 Environmental Metals, Excitotoxicity and ALS ATCHISON, WILLIAM MICHIGAN STATE UNIVERSITY MI $463,248
ALS 2015 NINDS 1F32NS090831-01A1 The contribution of cytoskeleton disruptions in ALS disease pathology DANIELSON, ERIC UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $54,194
ALS 2015 NIGMS 1F32GM113446-01A1 Therapeutic genome editing for amyotrophic lateral sclerosis GAJ, THOMAS UNIVERSITY OF CALIFORNIA BERKELEY CA $54,194
ALS 2015 NINDS 1F32NS092417-01 Identifying the mechanisms of neuronal fate commitment during direct conversion GALLOWAY, KATE UNIVERSITY OF SOUTHERN CALIFORNIA CA $54,194
ALS 2015 NINDS 5R01NS077863-05 Electrical and mechanical properties of motor units in a mouse model of ALS HECKMAN, CHARLES NORTHWESTERN UNIVERSITY AT CHICAGO IL $513,233
ALS 2015 NINDS 5R01NS085207-03 ALS/FTD mutant C9orf72-induced genetic and nuclear pathology in iPS cell models ROTHSTEIN, JEFFREY JOHNS HOPKINS UNIVERSITY MD $354,375
ALS 2015 NINDS 5U01NS084970-02 Development of an antisense oligonucleotide therapy for SOD1 Familial ALS MILLER, TIMOTHY WASHINGTON UNIVERSITY MO $443,780
ALS 2015 NIGMS 5R01GM043375-25 Functional Coupling of Steps in Genes Expression REED, ROBIN HARVARD MEDICAL SCHOOL MA $741,644
ALS 2015 NINDS 5R42NS083227-03 Commercialization of a Diagnostic test for amyotrophic lateral sclerosis (ALS) BOWSER, ROBERT IRON HORSE DIAGNOSTICS, INC. AZ $137,106
ALS 2015 NINDS 5R01NS087070-02 Cyclic EphA4 peptide antagonists for neuroprotection in ALS PASQUALE, ELENA SANFORD-BURNHAM MEDICAL RESEARCH INSTIT CA $682,467
ALS 2015 NIGMS 5R01GM108975-02 A Conserved Metalloprotease Required for Mitochondrial Maintenance and Protection KHALIMONCHUK, OLEH UNIVERSITY OF NEBRASKA LINCOLN NE $273,189
ALS 2015 NINDS 5R01NS087227-02 Using RNA signatures for therapy development in neurodegeneration due to C9orf72 expansions LAGIER-TOURENNE, CLOTILDE LUDWIG INSTITUTE FOR CANCER RES LTD CA $280,175
ALS 2015 NINDS 5R21NS089979-02 c9RAN proteins as a biomarker for C9ORF72-associated ALS and FTD GENDRON, TANIA MAYO CLINIC JACKSONVILLE FL $191,275
ALS 2015 NINDS 5R01NS089742-02 C9ORF72 in Motor System Biology and ALS EGGAN, KEVIN HARVARD UNIVERSITY MA $433,902
ALS 2015 NINDS 5R01NS090352-02 Misfolded ALS-linked Profilin-1: a novel therapeutic target BOSCO, DARYL UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $364,766
ALS 2015 NINDS 5U54NS091046-02 5987 Data Generation Core - Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells THOMPSON, LESLIE UNIVERSITY OF CALIFORNIA-IRVINE CA $700,364
ALS 2015 RMAP 5U54NS091046-02 5987 Data Generation Core - Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells THOMPSON, LESLIE UNIVERSITY OF CALIFORNIA-IRVINE CA $233,922
ALS 2015 NIA 5U01AG045390-02 Longitudinal Evaluation of Familial Frontotemporal Dementia Subjects (LEFFTDS) BOEVE, BRADLEY MAYO CLINIC ROCHESTER MN $1,648,463
ALS 2015 NINDS 5U01AG045390-02 Longitudinal Evaluation of Familial Frontotemporal Dementia Subjects (LEFFTDS) BOEVE, BRADLEY MAYO CLINIC ROCHESTER MN $1,753,684
ALS 2015 NINDS 5R21NS090912-02 Development of a mouse model of C9ORF72 ALS/FTD expressing RAN translated peptide TROTTI, DAVIDE THOMAS JEFFERSON UNIVERSITY PA $195,000
ALS 2015 NINDS 5R01NS089604-02 TDP-43 and Mitochondrial Dysfunction in ALS WANG, XINGLONG CASE WESTERN RESERVE UNIVERSITY OH $346,719
ALS 2015 NINDS 5P01NS084974-02 6281 Administrative Core PETRUCELLI, LEONARD MAYO CLINIC JACKSONVILLE FL $322,780
ALS 2015 NINDS 5P01NS084974-02 6282 Project 1: Molecular markers and phenotypic heterogeneity in c9FTD/ALS. BOYLAN, KEVIN MAYO CLINIC JACKSONVILLE FL $204,949
ALS 2015 NINDS 5P01NS084974-02 6283 Project 2: RAN translation and RNA-binding protein sequestration in c9FTD/ALS PETRUCELLI, LEONARD MAYO CLINIC JACKSONVILLE FL $64,555
ALS 2015 NINDS 5P01NS084974-02 6284 Project 3: Neuropathology of the multi-proteinopathy of c9FTD/ALS. DICKSON, DENNIS MAYO CLINIC JACKSONVILLE FL $114,237
ALS 2015 NINDS 5P01NS084974-02 6285 Core B: Clinical and Genetics Core BOYLAN, KEVIN MAYO CLINIC JACKSONVILLE FL $388,549
ALS 2015 NINDS 5P01NS084974-02 6286 Core C: Neuropathology DICKSON, DENNIS MAYO CLINIC JACKSONVILLE FL $196,063
ALS 2015 NIEHS 5R21ES024355-02 Exposure to cyanobacteria and BMAA in ALS through the gut environment microbiome OPHOFF, ROEL UNIVERSITY OF CALIFORNIA LOS ANGELES CA $192,500
ALS 2015 NCATS 5U54NS092091-02 6482 Project 1 BENATAR, MICHAEL UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $82,818
ALS 2015 NINDS 5U54NS092091-02 6482 Project 1 BENATAR, MICHAEL UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $149,459
ALS 2015 NCATS 5U54NS092091-02 6483 Project 2 BENATAR, MICHAEL UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $197,871
ALS 2015 NINDS 5U54NS092091-02 6483 Project 2 BENATAR, MICHAEL UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $357,094
ALS 2015 NCATS 5U54NS092091-02 6484 Pilot Demonstration BENATAR, MICHAEL UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $25,433
ALS 2015 NINDS 5U54NS092091-02 6484 Pilot Demonstration BENATAR, MICHAEL UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $45,898
ALS 2015 OD 1U54OD020351-01 5026 Project 6 - Amyotrophic Lateral Sclerosis Project LUTZ, CATHLEEN JACKSON LABORATORY ME $121,166
ALS 2015 NINDS 1R01NS092788-01 Modeling the progression of SOD1-linked motor neuron disease BORCHELT, DAVID UNIVERSITY OF FLORIDA FL $328,125
ALS 2015 NINDS 1R21NS093244-01 Investigating the contributions of astrocyte gap junctions to ALS disease progression MARAGAKIS, NICHOLAS JOHNS HOPKINS UNIVERSITY MD $243,000
ALS 2015 NINDS 1R21NS093469-01 Investigating mechanisms of UBQLN2-mediated neurodegenerative disease PAULSON, HENRY UNIVERSITY OF MICHIGAN MI $232,500
ALS 2015 NINDS 2R01NS063964-06A1 TDP-43, RNA Metabolism, and ALS/FTD Pathology LINK, CHRISTOPHER UNIVERSITY OF COLORADO CO $349,453
ALS 2015 NIGMS 2R01GM056350-17A1 Exploring the toxicity of aggregates associated with protein-misfolding diseases LIEBMAN, SUSAN UNIVERSITY OF NEVADA RENO NV $367,522
ALS 2015 NINDS 1R01NS089616-01A1 Investigating disease Mechanisms in C9orf72-linked ALS/FTD WANG, JIOU JOHNS HOPKINS UNIVERSITY MD $354,375
ALS 2015 NINDS 1R01NS088645-01A1 Etiological Linkage of DNA Damage/Repair Deficiency in Neurodegenerative Diseases HEGDE, MURALIDHAR METHODIST HOSPITAL RESEARCH INSTITUTE TX $370,321
ALS 2015 NINDS 2R01NS073873-05 Identification of ALS associated genes using whole genome sequencing LANDERS, JOHN UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $690,936
ALS 2015 NINDS 1R21NS088653-01A1 Development of a New ALS Mouse Model that Targets Profilin1 and Actin Filaments KIAEI, MAHMOUD UNIV OF ARKANSAS FOR MED SCIS AR $223,500
ALS 2015 NINDS 1R21NS088449-01A1 Transposable Elements in Frontotemporal Lobar Degeneration DUBNAU, JOSHUA COLD SPRING HARBOR LABORATORY NY $288,000
ALS 2015 NHLBI 4R00HL119606-02 Enhanced respiratory plasticity in models of respiratory motor neuron death NICHOLS, NICOLE UNIVERSITY OF MISSOURI-COLUMBIA MO $242,259
ALS 2015 NINDS 1R21NS092127-01A1 Does TDP-43 dysfunction in astrocytes trigger motor neuron degeneration? XU, ZUOSHANG UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $209,375
ALS 2015 NIGMS 3R01GM080742-08S2 Protein misfolding and aggregation DOKHOLYAN, NIKOLAY UNIV OF NORTH CAROLINA CHAPEL HILL NC $4,906
ALS 2015 NINDS 1F30NS093682-01 Evolution of Pathologic RNA-Protein Aggregates in Motor Neuron Disease WHEELER, JOSHUA UNIVERSITY OF COLORADO CO $34,636
ALS 2015 NINDS 1F30NS092262-01A1 Investigating V1 interneuron subtype diversity using embryonic stem cells HOANG, PHUONG COLUMBIA UNIVERSITY HEALTH SCIENCES NY $46,934
ALS 2015 NINDS 1F31NS092340-01A1 Defining Motor Neuron-Specific miRNAs in ALS LAWLER, MARIAH WASHINGTON UNIVERSITY MO $29,696
ALS 2015 NINDS 1R01NS093865-01 Defining the mechanisms of dipeptide repeat protein toxicity in C9orf72 ALS/FTD GITLER, AARON STANFORD UNIVERSITY CA $442,988
ALS 2015 NCATS 1U13NS093847-01 ALS Clinical Trials Guidelines MITSUMOTO, HIROSHI COLUMBIA UNIVERSITY HEALTH SCIENCES NY $10,000
ALS 2015 NINDS 1U13NS093847-01 ALS Clinical Trials Guidelines MITSUMOTO, HIROSHI COLUMBIA UNIVERSITY HEALTH SCIENCES NY $10,000
ALS 2015 NINDS 1R01NS093872-01 Metabolic profiling of sporadic ALS patients: from fibroblasts to neurons and back MANFREDI, GIOVANNI WEILL MEDICAL COLL OF CORNELL UNIV NY $548,362
ALS 2015 NINDS 4R00NS082376-03 Analysis of the RNA-binding Protein FUS and Its Role in Neurodegenerative Disease SCHWARTZ, JACOB UNIVERSITY OF ARIZONA AZ $252,872
ALS 2015 NINDS 3R01NS085207-02S1 ALS/FTD mutant C9orf72-induced genetic and nuclear pathology in iPS cell models ROTHSTEIN, JEFFREY JOHNS HOPKINS UNIVERSITY MD $40,500
ALS 2015 NINDS 2R37NS040389-12A1 Molecular Genetic Characterization of SCA8 RANUM, LAURA UNIVERSITY OF FLORIDA FL $639,176
ALS 2015 NINDS 3R01NS077982-03S1 Phase 1b Trial of stem cells in ALS GLASS, JONATHAN EMORY UNIVERSITY GA $36,505
ALS 2015 NINDS 1R56NS092572-01 Studies of NMJ structure and function in mutant FUS-ALS and beyond PASINELLI, PIERA THOMAS JEFFERSON UNIVERSITY PA $477,773
ALS 2015 NINDS 1R21NS094921-01 Mechanisms of C9orf72-associated dipeptide toxicity LAMITINA, SAMUEL UNIVERSITY OF PITTSBURGH AT PITTSBURGH PA $231,000
ALS 2015 NINDS 1R21NS094918-01 G-quadruplex Structures as Targets and Tools in ALS IVANOV, PAVEL BRIGHAM AND WOMEN'S HOSPITAL MA $266,188
ALS 2015 NINDS 1R21NS095157-01 Modeling Synaptic Vulnerability of a Brainstem Sensorimotor Circuit in a Mouse Model for Amyotrophic Lateral Sclerosis VENUGOPAL, SHARMILA UNIVERSITY OF CALIFORNIA LOS ANGELES CA $192,500
ALS 2015 NIGMS 3R01GM046295-20S1 Mechanisms and functions of subcellular motility SAXTON, WILLIAM UNIVERSITY OF CALIFORNIA SANTA CRUZ CA $87,144
ALS 2015 NINDS 1R01NS092067-01A1 Regulation of glutamate transport in astrocyte subtypes and in ALS ROBINSON, MICHAEL CHILDREN'S HOSP OF PHILADELPHIA PA $485,636
ALS 2015 NINDS 1R01NS091299-01A1 RNA dysregulation in neurodegeneration ZARNESCU, DANIELA UNIVERSITY OF ARIZONA AZ $334,296
ALS 2015 NINDS 1R01NS091110-01A1 Treatment of ALS based on transplantation of glial restricted progenitors WALCZAK, PIOTR JOHNS HOPKINS UNIVERSITY MD $369,795
ALS 2015 NINDS 1R21NS091860-01A1 Investigating the response of FUS/TLS to excitotoxic insult BOSCO, DARYL UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $251,250
ALS 2015 NINDS 1R21NS091953-01A1 Mechanisms Mediating NMJ Dennervation MILLIGAN, CAROL WAKE FOREST UNIVERSITY HEALTH SCIENCES NC $232,500
ALS 2015 NINDS 4R00NS087104-02 Novel mechanisms of actin dynamics underlying cell motility, axon growth, and ALS VITRIOL, ERIC UNIVERSITY OF FLORIDA FL $249,000
ALS 2015 NINDS 3R01NS077982-03S2 Phase 1b Trial of stem cells in ALS GLASS, JONATHAN EMORY UNIVERSITY GA $54,673
ALS 2015 NIDCD 1R43DC015192-01 Superior laryngeal nerve stimulation for the treatment of neurogenic dysphagia in an animal model of amyotrophic lateral sclerosis KHODAPARAST, NAVID NUVIANT MEDICAL INC. TX $175,705
ALS 2015 NINDS 1R43NS095481-01 TDP-43 aggregation inhibitors for the treatment of ALS LARSEN, GLENN AQUINNAH PHARMACEUTICALS, INC. MA $499,556
ALS 2015 NINDS 1F31NS095698-01 Untargeted metabolite profiling of sporadic ALS patient fibroblasts: identifying mechanisms of the disease SCHWARTZ, BENJAMIN WEILL MEDICAL COLL OF CORNELL UNIV NY $43,120
ALS 2015 NINDS 1F31NS095571-01 Exploring synaptic abnormalities that underlie hyperactivity in a stem-cell derived model of amyotrophic lateral sclerosis SMERDON, JOHN COLUMBIA UNIVERSITY HEALTH SCIENCES NY $43,120
ALS 2015 NINDS 1R21NS095635-01 A new antibody/RNAi combination therapy strategy for ALS XU, ZUOSHANG UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $209,375
ALS 2015 NIGMS 3R01GM108975-02S1 A Conserved Metalloprotease Required for Mitochondrial Maintenance and Protection KHALIMONCHUK, OLEH UNIVERSITY OF NEBRASKA LINCOLN NE $55,750
ALS 2015 NINDS 3U01NS084970-02S1 Development of an antisense oligonucleotide therapy for SOD1 Familial ALS MILLER, TIMOTHY WASHINGTON UNIVERSITY MO $144,807
ALS 2015 NINDS 4K22NS091314-02 Epigenetics In Neurodegenerative Disease: Targeting Histone Modifications in ALS TORRENTE, MARIANA BROOKLYN COLLEGE NY $111,405
ALS 2015 NINDS 3R42NS083227-03S1 Commercialization of a Diagnostic test for amyotrophic lateral sclerosis (ALS) BOWSER, ROBERT IRON HORSE DIAGNOSTICS, INC. AZ $5,000
ALS 2015 NIEHS 1ZIAES049005-24 Lead And Other Neurotoxins As Risk Factors For Amyotrophic Lateral Sclerosis SANDLER, DALE NIH $119,784
ALS 2015 NIA 1ZIAAG000933-08 Genetic etiology of Amyotrophic Lateral Sclerosis TRAYNOR, BRYAN NIH $809,613
ALS 2015 NIA 1ZIAAG000934-07 Genetic etiology of Fronto-Temporal Dementia TRAYNOR, BRYAN NIH $441,607
ALS 2015 NIA 1ZIAAG000943-08 Function and Pathogenic Mechanism of VAPB in ALS and Other Motor Neuron Diseases CAI, HUAIBIN NIH $88,321
ALS 2015 NIA 1ZIAAG000951-14 Genetic Analysis Of Non-alzheimer Dementias SINGLETON, ANDREW NIH $451,421
ALS 2015 NINDS 3P01NS084974-02S1 Pathobiology of Neurodegeneration in C9ORF72 Repeat Expansion PETRUCELLI, LEONARD MAYO CLINIC JACKSONVILLE FL $107,627
ALS 2015 NICHD 1ZIAHD008892-07 Mechanisms of Motor Neuron Disease KALER, STEPHEN NIH $254,589
ALS 2015 NINDS 1ZIANS002976-17 Spasticity and Upper Motor Neuron Disorders FLOETER, MARY KAY NIH $1,034,640
ALS 2015 NINDS 1ZIANS003146-01 Natural history and biomarker discovery in C9orf72 Amyotrophic lateral sclerosis and frontotemporal dementia FLOETER, MARY KAY NIH $396,134


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