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RCDC

Project Listing by Category


Back to Estimates of Funding for Various Research, Condition, and Disease Categories (RCDC) Click the column headings to sort project listings.
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CategoryFYFunding ICProject NumberSub Project #Project TitlePI NameOrg NameState / CountryAmount
Orphan Drug 2011 NIDDK 5R33DK070341-05 Novel Therapies for Resistant FSGS TRACHTMAN, HOWARD FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH NY $1
Orphan Drug 2011 NIAID 1U01AI088650-01 Myeloid-lineage cells and immunopathology in Leishmania braziliensis SCOTT, PHILLIP UNIVERSITY OF PENNSYLVANIA PA $636,943
Orphan Drug 2011 NIDA 5R44DA023737-03 New Drugs to Enhance Endocannabinoid Responses for Treating Excitotoxicity, Phase GOLIK, JERZY MAKSCIENTIFIC, LLC MA $516,628
Orphan Drug 2011 NIAID 4R37AI034885-18 Peroxides for Chemotherapy of Malaria and Cancer POSNER, GARY JOHNS HOPKINS UNIVERSITY MD $453,689
Orphan Drug 2011 NCI 5R01CA129963-05 Tailoring New Drugs in Pancreatic Cancer HIDALGO, MANUEL SPANISH NATIONAL CANCER CENTER SPAIN $121,828
Orphan Drug 2011 NHLBI 7R01HL095511-02 TCD with Transfusions Changing to Hydroxyurea - SDMC DAVIS, BARRY UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON TX $726,102
Orphan Drug 2011 NIDDK 2R01DK070790-06 RENAL OSTEODYSTROPHY AND VASCULAR CALCIFICATION HRUSKA, KEITH WASHINGTON UNIVERSITY MO $228,000
Orphan Drug 2011 NIDDK 5R01DK080740-03 Medication Adherence in Children Who Had a Liver Transplant (MALT) SHEMESH, EYAL MOUNT SINAI SCHOOL OF MEDICINE NY $677,432
Orphan Drug 2011 NHLBI 1P01HL103455-01 8754 Translational vascular phenomics, genomics, and epidemology MORRIS, ALISON UNIVERSITY OF PITTSBURGH $483,404
Orphan Drug 2011 NCI 5F31CA144560-02 Protein dynamics of calcium-S100A5 in the presence and absence of target peptide LIRIANO, MELISSA UNIVERSITY OF MARYLAND BALTIMORE MD $38,673
Orphan Drug 2011 NIGMS 1R21GM086689-01A2 Bayesian hierarchical nonlinear models for pharmacogenomic cytotoxicity studies FRIDLEY, BROOKE MAYO CLINIC MN $118,275
Orphan Drug 2011 NIAID 1R01AI090662-01 Validation of New Antimalarial Leads WATERSON, DAVID MEDICINES FOR MALARIA VENTURE SWITZE $1,238,884
Orphan Drug 2011 NCI 5R01CA050947-19 Molecular Sequelae of Myeloma-Bone Marrow Interactions: Therapeutic Applications ANDERSON, KENNETH DANA-FARBER CANCER INSTITUTE MA $278,781
Orphan Drug 2011 NCI 5R01CA124648-05 An integrative approach to cancer gene discovery in hepatocellular carcinoma POWERS, SCOTT COLD SPRING HARBOR LABORATORY NY $435,619
Orphan Drug 2011 NCI 5R01CA078814-13 New Triterpenoids for Chemoprevention and Therapy of Cancer SPORN, MICHAEL DARTMOUTH COLLEGE NH $340,825
Orphan Drug 2011 NHLBI 5R01HL087836-04 In vivo function and tolerance to Factor VIII variants LEE, BRENDAN BAYLOR COLLEGE OF MEDICINE TX $383,750
Orphan Drug 2011 NIAID 5R01AI077414-03 Define the role of dendritic cells in HTLV-1 associated neuroinflammatory disease JAIN, POOJA DREXEL UNIVERSITY PA $369,890
Orphan Drug 2011 NCI 4R37CA031845-31 Synthetic Studies Related to Cancer Research/Treatment WENDER, PAUL STANFORD UNIVERSITY CA $423,345
Orphan Drug 2011 NCI 5R01CA136803-03 Investigation of Notch-inhibiting microRNAs in glioma PUROW, BENJAMIN UNIVERSITY OF VIRGINIA CHARLOTTESVILLE VA $304,690
Orphan Drug 2011 NICHD 5R01HD020521-25 Molecular Cloning of the Fragile X Site WARREN, STEPHEN EMORY UNIVERSITY GA $568,641
Orphan Drug 2011 NCI 5R01CA139389-02 Lymphoma Therapy with Reprogrammed Measles Viruses CATTANEO, ROBERTO MAYO CLINIC MN $304,127
Orphan Drug 2011 NIGMS 5R01GM054051-15 Substrate Activity Screening: A New Approach to Inhibitor Discovery ELLMAN, JONATHAN YALE UNIVERSITY CT $428,042
Orphan Drug 2011 NIAID 5R01AI065529-05 Regulatory Networks of Helicobacter pylori MERRELL, D HENRY M. JACKSON FDN FOR THE ADV MIL/MED MD $367,285
Orphan Drug 2011 NHLBI 5R01HL085133-04 Novel Peptide for Dynamic Regulation of Lung Endothelium NOS/cGMP Functions PATEL, JAWAHARLAL UNIVERSITY OF FLORIDA FL $315,000
Orphan Drug 2011 NCI 5R01CA113669-07 Developmental Signaling Pathways in Pancreatic Cancer MAITRA, ANIRBAN JOHNS HOPKINS UNIVERSITY MD $306,839
Orphan Drug 2011 NCI 5R01CA132861-03 SYNTHESES AND CELLULAR STUDIES OF NEW PHOTOSENSITIZERS FOR MEDICAL APPLICATIONS SMITH, KEVIN LOUISIANA STATE UNIV A&M COL BATON ROUGE LA $295,874
Orphan Drug 2011 NIAID 5R01AI077638-03 Roles of two aminopeptidases in peptide catabolism in the malaria parasite KLEMBA, MICHAEL VIRGINIA POLYTECHNIC INST AND ST UNIV VA $263,579
Orphan Drug 2011 NIAID 5R01AI057460-08 Group 1 CD1 in Infectious Disease and T Cell Development WANG, CHYUNG-RU NORTHWESTERN UNIVERSITY AT CHICAGO IL $377,438
Orphan Drug 2011 NIAID 5R01AI078251-03 Novel Antimicrobials Targeting Cell Division OJIMA, IWAO STATE UNIVERSITY NEW YORK STONY BROOK NY $376,282
Orphan Drug 2011 NIAID 5R01AI043197-14 Alternative approaches for NALT-based immunity to respiratory pathogens BOYAKA, PROSPER OHIO STATE UNIVERSITY OH $367,538
Orphan Drug 2011 NIMH 5R01MH085802-02 Mechanisms and Therapeutics for Rett Syndrome SUR, MRIGANKA MASSACHUSETTS INSTITUTE OF TECHNOLOGY MA $415,800
Orphan Drug 2011 NCI 5R01CA125541-05 Studies of a Novel Therapeutic Target in Non-Small Cell Lung Cancer (NSCLC) SALGIA, RAVI UNIVERSITY OF CHICAGO IL $254,610
Orphan Drug 2011 NCI 5R01CA089341-08 Functional Characterization of MLL Gene Fusions CALIGIURI, MICHAEL OHIO STATE UNIVERSITY OH $278,052
Orphan Drug 2011 NIGMS 5R01GM087638-04 Chemistry and Biology of Bacterial Sulfonucleotide Reductases CARROLL, KATE SCRIPPS FLORIDA FL $500,021
Orphan Drug 2011 NCI 5R01CA086335-10 Therapeutic modulation of angiogenesis in human gliomas VAN MEIR, ERWIN EMORY UNIVERSITY GA $340,601
Orphan Drug 2011 NCI 5R01CA025000-32 CD8+ T Cell-Mediated Immunotherapy of Autochthonous SV40 T Antigen-Induced Tumors SCHELL, TODD PENNSYLVANIA STATE UNIV HERSHEY MED CTR PA $374,436
Orphan Drug 2011 NIAID 5U01AI069421-05 GHESKIO HIV Clinical Trial Unit PAPE, JEAN GHESKIO CENTER HAITI $1,638,659
Orphan Drug 2011 NIAID 5R01AI071223-04 Experimental Molecular Vaccines for Schistosomiasis SIDDIQUI, AFZAL TEXAS TECH UNIVERSITY HEALTH SCIS CENTER TX $603,099
Orphan Drug 2011 NEI 5R01EY015128-07 Retinal Remodeling MARC, ROBERT UNIVERSITY OF UTAH UT $423,180
Orphan Drug 2011 NCI 5R01CA136895-03 Molecular targets in diffuse large B cell lymphoma DAVE, SANDEEP DUKE UNIVERSITY NC $251,191
Orphan Drug 2011 NCI 5R01CA127935-03 Boronated nucleosides for neutron capture therapy of brain tumors TJARKS, WERNER OHIO STATE UNIVERSITY OH $249,684
Orphan Drug 2011 NIAMS 5R03AR056838-03 Mechanisms of BMP Receptor Kinase Dysregulation in Skeletal Dysplasias GROPPE, JAY TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR TX $69,617
Orphan Drug 2011 NCI 7R01CA142873-02 The GNAQ pathway as a therapeutic target in uveal melanoma BASTIAN, BORIS SLOAN-KETTERING INSTITUTE FOR CANCER RES NY $49,462
Orphan Drug 2011 NCI 5R01CA129609-03 Chemoprevention of Head & Neck Cancer Using Controlled Release Polymers MALLERY, SUSAN OHIO STATE UNIVERSITY OH $304,087
Orphan Drug 2011 NHLBI 5K23HL090832-03 Functional assessment in the management of sickle cell pain in children ZEMPSKY, WILLIAM CONNECTICUT CHILDREN'S MEDICAL CENTER CT $121,230
Orphan Drug 2011 NCI 5R21CA141348-02 Dynamic multimodal imaging of tumor hypoxia and vascular profiles in glioblastoma ZHAO, DAWEN UNIVERSITY OF TEXAS SW MED CTR/DALLAS TX $167,198
Orphan Drug 2011 NEI 5R01EY018656-04 Compacted DNA Nanoparticles for Ocular Therapy NAASH, MUNA UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR OK $351,600
Orphan Drug 2011 NCI 5R01CA124951-02 Novel CTD inhibitors with synthetic lethality to oncogenic Ras for cancer therapy FANG, BINGLIANG UNIVERSITY OF TEXAS MD ANDERSON CAN CTR TX $309,964
Orphan Drug 2011 NINDS 5R01NS061920-03 Calcium Permeable AMPA Receptors: Signaling, Toxicity and Control ZIFF, EDWARD NEW YORK UNIVERSITY SCHOOL OF MEDICINE NY $363,366
Orphan Drug 2011 NCI 5R21CA139290-02 Mitochondrial Dysfunction and Chemoresistance in Malignant Gliomas GRIGUER, CORINNE UNIVERSITY OF ALABAMA AT BIRMINGHAM AL $154,539
Orphan Drug 2011 NCI 5R21CA143785-02 Enhancing antitumor immunity with anti-PD-1 antibody in follicular lymphoma. NEELAPU, SATTVA UNIVERSITY OF TEXAS MD ANDERSON CAN CTR TX $279,772
Orphan Drug 2011 NCI 5R01CA127494-03 Proteasome Inhibition and ER Stress MCCONKEY, DAVID UNIVERSITY OF TEXAS MD ANDERSON CAN CTR TX $247,971
Orphan Drug 2011 NHLBI 5R01HL093022-02 E-cadherin shedding in chronic lung injury MCGUIRE, JOHN UNIVERSITY OF WASHINGTON WA $415,000
Orphan Drug 2011 NIDDK 5R01DK075309-04 Keeping CFTR in its Place: An Integrated Small-Molecule Approach MADDEN, DEAN DARTMOUTH COLLEGE NH $417,278
Orphan Drug 2011 NHLBI 5R01HL092831-03 Exhaled Nitric Oxide and Oxidative Stress in Pulmonary Arterial Hypertention Asso GIRGIS, REDA JOHNS HOPKINS UNIVERSITY MD $287,000
Orphan Drug 2011 NICHD 5U10HD063106-02 Collaborative Pediatric Research Critical Care Network(U10) SHANLEY, THOMAS UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $255,317
Orphan Drug 2011 NHLBI 5K08HL090785-03 Tissue Factor Mediated Fibrin Deposition in Acute Lung Injury BASTARACHE, JULIE VANDERBILT UNIVERSITY TN $125,739
Orphan Drug 2011 NCI 5R01CA143107-02 Berberine downregulates MDM2 by interaction with DAXX in cancer cells ZHOU, MUXIANG EMORY UNIVERSITY GA $311,976
Orphan Drug 2011 NCI 5R21CA132277-02 Adoptive T-Cell Therapy for Acute Leukemia BALL, EDWARD UNIVERSITY OF CALIFORNIA SAN DIEGO CA $310,970
Orphan Drug 2011 NINDS 5R01NS055315-04 Mechanisms of SOD1 toxicity in ALS ELLIOTT, JEFFREY UNIVERSITY OF TEXAS SW MED CTR/DALLAS TX $302,913
Orphan Drug 2011 NCI 5R01CA139099-02 Molecular Combinatorial Therapy of Glioblastoma Multiforme DEBINSKI, WALDEMAR WAKE FOREST UNIVERSITY HEALTH SCIENCES NC $309,154
Orphan Drug 2011 NCI 5R01CA121327-05 Molecular Basis Of Renal Cell Carcinoma Response to SU11428 MOTZER, ROBERT SLOAN-KETTERING INSTITUTE FOR CANCER RES NY $336,532
Orphan Drug 2011 NCI 5R37CA028824-33 Synthesis of Antitumor Natural Products DANISHEFSKY, SAMUEL SLOAN-KETTERING INSTITUTE FOR CANCER RES NY $771,834
Orphan Drug 2011 NINDS 5F30NS067938-02 Defining the Role of TDP-43 in Neurodegenerative Disease Pathways WEGORZEWSKA, IGA WASHINGTON UNIVERSITY MO $46,800
Orphan Drug 2011 NHLBI 5R01HL038794-22 Membrane Proteins of Normal and Abnormal Red Cells SPEICHER, DAVID WISTAR INSTITUTE PA $466,485
Orphan Drug 2011 NCI 5U01CA137443-03 Adult Brain Tumor Consortium (ABTC) GROSSMAN, STUART JOHNS HOPKINS UNIVERSITY MD $1,905,232
Orphan Drug 2011 NIGMS 5R01GM067785-08 Hsp40 and conformational disease CYR, DOUGLAS UNIVERSITY OF NORTH CAROLINA CHAPEL HILL NC $283,038
Orphan Drug 2011 NCI 5R01CA130817-04 Interplay Between Cancer and Immune Cells on Targeted Therapy LEE, PETER STANFORD UNIVERSITY CA $450,198
Orphan Drug 2011 NCI 5R01CA131408-03 HIF genes in head and neck cancer radiotherapy LI, CHUAN-YUAN UNIVERSITY OF COLORADO DENVER CO $300,270
Orphan Drug 2011 NCI 5R01CA076287-13 Pretargeted Radioimmunotherapy of CD20+ Lymphomas PRESS, OLIVER FRED HUTCHINSON CANCER RESEARCH CENTER WA $353,533
Orphan Drug 2011 NCI 5R01CA082830-10 Enhancing Activity of Alkylating Agents in Neuroblastoma REYNOLDS, CHARLES TEXAS TECH UNIVERSITY HEALTH SCIS CENTER TX $229,187
Orphan Drug 2011 NHLBI 5R01HL096376-02 Cardiolipin Induced Lung Injury and FIC1 MALLAMPALLI, RAMA UNIVERSITY OF PITTSBURGH AT PITTSBURGH PA $465,889
Orphan Drug 2011 NHLBI 5K24HL086796-05 Proteomic-based Approach to Ventilator Associated Pneumonia SCHNAPP, LYNN UNIVERSITY OF WASHINGTON WA $164,728
Orphan Drug 2011 NIAID 5R01AI080651-03 Development of a cell-based HTS for compounds with activity against tuberculosis RUSSELL, DAVID CORNELL UNIVERSITY ITHACA NY $266,495
Orphan Drug 2011 NCI 5R21CA141404-02 Multiple kinase target inhibition with EMND-2076 in multiple myeloma FARAG, SHERIF INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS IN $309,964
Orphan Drug 2011 NIAID 5R43AI088952-02 SQ109 for treatment of MDR-TB EINCK, LEO SEQUELLA, INC. MD $299,797
Orphan Drug 2011 NCI 5R01CA133662-03 Novel Compounds to Inactivate Oncogenic Fusion Proteins TORETSKY, JEFFREY GEORGETOWN UNIVERSITY DC $308,958
Orphan Drug 2011 NIAID 5R01AI078947-03 Chemically Mapping Malarial Rupture Proteases BOGYO, MATTHEW STANFORD UNIVERSITY CA $393,824
Orphan Drug 2011 NINDS 5R01NS040511-12 Oligodendrocyte Lineage Gene Function in the CNS ROWITCH, DAVID UNIVERSITY OF CALIFORNIA SAN FRANCISCO CA $433,526
Orphan Drug 2011 NCI 5R01CA133525-04 Targeted Therapeutics of LGL Leukemia utilizing Ceramide Nanoliposomes LOUGHRAN, THOMAS PENNSYLVANIA STATE UNIV HERSHEY MED CTR PA $303,925
Orphan Drug 2011 NCI 5R01CA143032-02 Molecular Targeting of Diffuse Large B-cell Lymphoma MELNICK, ARI WEILL MEDICAL COLLEGE OF CORNELL UNIV NY $587,846
Orphan Drug 2011 NIAID 5R01AI031940-21 Genetic Analysis of Cholera Toxin Structure and Function HOLMES, RANDALL UNIVERSITY OF COLORADO DENVER CO $587,976
Orphan Drug 2011 NHLBI 5R01HL069438-09 Adhesion mechanisms mediating sickle cell vasoocclusion in vivo FRENETTE, PAUL ALBERT EINSTEIN COL OF MED YESHIVA UNIV NY $415,000
Orphan Drug 2011 NINDS 5R01NS057412-05 Suppression of the Idua-W402X mutation in an MPS I-H mouse BEDWELL, DAVID UNIVERSITY OF ALABAMA AT BIRMINGHAM AL $310,844
Orphan Drug 2011 NICHD 1R01HD062484-01A1 Pharmacogenetic Determinants of Vincristine Toxicity and Response RENBARGER, JAMIE INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS IN $438,042
Orphan Drug 2011 NCI 5R01CA100634-09 Radiovirotherapy for Multiple Myeloma RUSSELL, STEPHEN MAYO CLINIC MN $318,489
Orphan Drug 2011 NHLBI 5R01HL095791-02 Novel Biologic Therapies for BMT: Mechanistic Evaluation in Rhesus Macaques KEAN, LESLIE EMORY UNIVERSITY GA $826,095
Orphan Drug 2011 NINDS 5R01NS056086-04 Elucidating the Relations of Heat Shock Factors, Molecular Chaperones and Prions LI, LIMING NORTHWESTERN UNIVERSITY AT CHICAGO IL $321,214
Orphan Drug 2011 NIGMS 1SC1AI096108-01A2 Towards a vaccine against Fasciola hepatica using FhSAP2 as an antigen ESPINO, ANA UNIVERSITY OF PUERTO RICO MED SCIENCES PR $225,000
Orphan Drug 2011 NCI 5R01CA121258-05 Cellular Transduction with Replication-Competent Retrovirus Vectors KASAHARA, NORIYUKI UNIVERSITY OF CALIFORNIA LOS ANGELES CA $476,828
Orphan Drug 2011 NCI 5R01CA139032-03 AID-mediated genetic instability in BCR-ABL1-transformed B cell lineage leukemia MUSCHEN, MARKUS CHILDREN'S HOSPITAL LOS ANGELES CA $322,040
Orphan Drug 2011 NCI 5R01CA102707-07 Inhibition of Cytochrome c-induced Caspase Activation KORNBLUTH, SALLY DUKE UNIVERSITY NC $263,055
Orphan Drug 2011 NCI 1R01CA154348-01 Measles Virotherapy and radiovirotherapy in the Treatment of recurrent gliomas GALANIS, EVANTHIA MAYO CLINIC MN $328,355
Orphan Drug 2011 NCI 5R01CA138535-02 Novel Heparanase Inhibitors for Cancer Therapy SANDERSON, RALPH UNIVERSITY OF ALABAMA AT BIRMINGHAM AL $333,895
Orphan Drug 2011 NIAID 5R01AI072584-04 Mechanism of host cell apoptosis inhibition by Mycobacterium tuberculosis BRIKEN, VOLKER UNIVERSITY OF MARYLAND COLLEGE PK CAMPUS MD $330,785
Orphan Drug 2011 NCI 5R01CA132091-04 Targeted Nanoparticle DNA Therapy for Ovarian Cancer SAWICKI, JANET LANKENAU INSTITUTE FOR MEDICAL RESEARCH PA $266,946
Orphan Drug 2011 NCI 1R01CA154365-01 Identification and Characterization of Gene Fusions in Lung Adenocarcinoma BEER, DAVID UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $284,052
Orphan Drug 2011 NEI 1R24EY019861-01A1 Therapeutic approaches for ABCA4-associated disorders ALLIKMETS, RANDO COLUMBIA UNIVERSITY HEALTH SCIENCES NY $1,502,680
Orphan Drug 2011 NCI 5R01CA073507-14 In Vivo Model of Epstein-Barr Virus Latency LONGNECKER, RICHARD NORTHWESTERN UNIVERSITY AT CHICAGO IL $366,175
Orphan Drug 2011 NHLBI 5R01HL077783-06 A New Pathway for Neutrophil-induced Airway Inflammation BLALOCK, J. UNIVERSITY OF ALABAMA AT BIRMINGHAM AL $362,633
Orphan Drug 2011 NCI 5R01CA098468-08 Improving CPT-11 Efficacy Using Structural and Chemical Biology REDINBO, MATTHEW UNIVERSITY OF NORTH CAROLINA CHAPEL HILL NC $254,334
Orphan Drug 2011 NCI 5R01CA087952-10 TRAIL Therapy for Rhabdomyosacrcoma HOUGHTON, JANET CLEVELAND CLINIC LERNER COL/MED-CWRU OH $227,795
Orphan Drug 2011 NCI 5R01CA101850-07 ENGINEERED INTELLIGENT MICELLE FOR TUMOR pH TARGETING BAE, YOU UNIVERSITY OF UTAH UT $263,045
Orphan Drug 2011 NINDS 5R01NS065890-02 HSF1 as a therapeutic target in neurodegenerative disease THIELE, DENNIS DUKE UNIVERSITY NC $330,080
Orphan Drug 2011 NCI 5R01CA138738-03 Adoptive Immunotherapy of Cancer with IL-12 Secreting Tumor-Targeted T cells BRENTJENS, RENIER SLOAN-KETTERING INSTITUTE FOR CANCER RES NY $381,617
Orphan Drug 2011 NIGMS 5R01GM072611-06 Statistical Methods for Ultrahigh-dimensional Biomedical Data FAN, JIANQING PRINCETON UNIVERSITY NJ $267,323
Orphan Drug 2011 NCI 5R01CA141341-11 Rac GTPase-Specific Small Molecular Inhibitors ZHENG, YI CHILDREN'S HOSPITAL MEDICAL CENTER CINCI OH $243,433
Orphan Drug 2011 NIDCD 5R01DC009972-02 Hearing impairment in HIV-infected and HIV/TB-coinfected individuals in Tanzania BUCKEY, JAY DARTMOUTH COLLEGE NH $513,039
Orphan Drug 2011 NCI 5R21CA149872-02 Peptide-Based Vaccine Therapy for Childhood Malignant Gliomas POLLACK, IAN UNIVERSITY OF PITTSBURGH AT PITTSBURGH PA $304,932
Orphan Drug 2011 NINDS 1R01NS072114-01 Neuronal nicotinic receptor modulation and cerebellar ataxias WECKER, LYNN UNIVERSITY OF SOUTH FLORIDA FL $309,225
Orphan Drug 2011 NCI 1R01CA154802-01 Approaches to discover and quantify apoptotic biomarkers for cancer treatment WELLS, JAMES UNIVERSITY OF CALIFORNIA SAN FRANCISCO CA $320,588
Orphan Drug 2011 NCI 5R01CA102031-07 Phamacological modulation of epigenetic changes in AML MARCUCCI, GUIDO OHIO STATE UNIVERSITY OH $291,000
Orphan Drug 2011 NCI 5R01CA132946-04 Pharmacogenetics of Ara-C Metabolic Pathway LAMBA, JATINDER UNIVERSITY OF MINNESOTA TWIN CITIES MN $277,663
Orphan Drug 2011 NIGMS 1R01GM095606-01 Coiled-coil Based Drug-Free Macromolecular Therapeutics KOPECEK, JINDRICH UNIVERSITY OF UTAH UT $284,050
Orphan Drug 2011 NHLBI 5R01HL092179-03 Hematopoietic gene therapy for hemophilia A DOERING, CHRISTOPHER EMORY UNIVERSITY GA $387,500
Orphan Drug 2011 NIAID 2R01AI064768-06 Biology of lipoamide dehydrogenase and 2-hydroxy-3-oxoadipate synthase in Mtb NATHAN, CARL WEILL MEDICAL COLLEGE OF CORNELL UNIV NY $876,693
Orphan Drug 2011 NCI 5R01CA142746-02 Enzyme-instructed self-assembly for anticancer nanomedicine XU, BING BRANDEIS UNIVERSITY MA $318,015
Orphan Drug 2011 NIAID 5R01AI047818-11 Biosynthesis of the Antibiotic Polyketide Enterocin MOORE, BRADLEY UNIVERSITY OF CALIFORNIA SAN DIEGO CA $250,789
Orphan Drug 2011 NCI 5R01CA083724-10 Chromosomal Abnormalities in Myeloma as Detected by FISH FONSECA, RAFAEL MAYO CLINIC ARIZONA AZ $320,322
Orphan Drug 2011 NIGMS 5R01GM052418-12 Mass Spectrometry Studies on Radical Reactions of DNA KENTTAMAA, HILKKA PURDUE UNIVERSITY WEST LAFAYETTE IN $210,739
Orphan Drug 2011 NCCAM 5F31AT005386-02 Efficacy evaluation of traditionally used antimalarial plants GRAZIOSE, ROCKY RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK NJ $30,481
Orphan Drug 2011 NINDS 5R01NS066278-02 Role of MELK in glioblastomas TERSKIKH, ALEXEY SANFORD-BURNHAM MEDICAL RESEARCH INSTIT CA $399,939
Orphan Drug 2011 NIAID 1R21AI091921-01 The Lysosome of Trypanosoma brucei: A Proteomic Analysis BANGS, JAMES UNIVERSITY OF WISCONSIN MADISON WI $197,750
Orphan Drug 2011 NCI 1R01CA155056-01 Targeting hypoxic microenvironment in Acute Lymphocytic Leukemia KONOPLEVA, MARINA UNIVERSITY OF TEXAS MD ANDERSON CAN CTR TX $341,354
Orphan Drug 2011 NCI 1R01CA154754-01 Engineering and Evaluation of Human L-Methionase for Cancer Therapy GEORGIOU, GEORGE UNIVERSITY OF TEXAS AUSTIN TX $442,512
Orphan Drug 2011 NHLBI 1K08HL105466-01 Novel Pathways of Inflammation and Biofilm Regulation in the Lung WILLIAMS, BRYAN UNIVERSITY OF MINNESOTA TWIN CITIES MN $137,160
Orphan Drug 2011 NCI 5R01CA135011-03 Development of a gold nanoparticles based targeted delivery system MUKHERJEE, PRIYABRATA MAYO CLINIC MN $304,127
Orphan Drug 2011 NCI 5R01CA142637-02 CD147 as a Novel Target in Head and Neck Cancer ROSENTHAL, EBEN UNIVERSITY OF ALABAMA AT BIRMINGHAM AL $265,382
Orphan Drug 2011 NIGMS 1R01GM100785-01 Mechanisms of Kinase Function and Drug Resistance in Cancer SAUER, KARSTEN SCRIPPS RESEARCH INSTITUTE CA $365,320
Orphan Drug 2011 NCI 1R01CA155143-01 Predictors of clinical outcome after therapeutic vaccination in follicular lympho NEELAPU, SATTVA UNIVERSITY OF TEXAS MD ANDERSON CAN CTR TX $494,701
Orphan Drug 2011 NIAID 1R01AI091882-01 Inhaled Caprazamycin for Tuberculolsis Therapy HICKEY, ANTHONY RESEARCH TRIANGLE INSTITUTE NC $266,824
Orphan Drug 2011 NCI 5R01CA129611-04 Development of JS-K as an anti-leukemic agent SHAMI, PAUL UNIVERSITY OF UTAH UT $302,919
Orphan Drug 2011 NCI 5R01CA103642-08 Immune surveillance in murine gammaherpesvirus infection USHERWOOD, EDWARD DARTMOUTH COLLEGE NH $276,154
Orphan Drug 2011 NINDS 1R01NS072420-01 DUSP26: A Novel Therapeutic Target in Neuroblastoma YANG, JIANHUA BAYLOR COLLEGE OF MEDICINE TX $342,344
Orphan Drug 2011 NINDS 1R21NS072182-01 Pre-clinical testing of necrostatin as a potential small molecule for the treatme PRZEDBORSKI, SERGE COLUMBIA UNIVERSITY HEALTH SCIENCES NY $240,750
Orphan Drug 2011 NHLBI 1R01HL106300-01 Gene Therapy for hemophilia using muscle-expressed FVIIa HIGH, KATHERINE CHILDRENS HOSPITAL OF PHILADELPHIA PA $538,654
Orphan Drug 2011 NCI 1R21CA155393-01 MCM Helicase as a Novel Target for Pancreatic Cancer Treatment ALEXANDROW, MARK H. LEE MOFFITT CANCER CTR & RES INST FL $217,935
Orphan Drug 2011 NCI 1K23CA154532-01 Allogeneic stem cell transplant with grafts depleted of naive T cells for leukemi BLEAKLEY, MARIE FRED HUTCHINSON CANCER RESEARCH CENTER WA $169,590
Orphan Drug 2011 NCI 1R01CA155360-01 Infant and Toddler Brain Tumors OLSON, JAMES FRED HUTCHINSON CANCER RESEARCH CENTER WA $365,200
Orphan Drug 2011 NHLBI 1K08HL107142-01 Chloride secretagogues for acquired CFTR dysfunction in chronic rhinosinusitis WOODWORTH, BRADFORD UNIVERSITY OF ALABAMA AT BIRMINGHAM AL $133,596
Orphan Drug 2011 NCI 1R21CA156009-01 Serum exosome biomarkers for evaluation of glioma drug response BREAKEFIELD, XANDRA MASSACHUSETTS GENERAL HOSPITAL MA $230,985
Orphan Drug 2011 NCI 1R21CA156056-01 Chemical Inhibitors of Rhabdomyosarcoma Self-Renawal LANGENAU, DAVID MASSACHUSETTS GENERAL HOSPITAL MA $224,286
Orphan Drug 2011 NIAID 5R01AI071163-04 Lentiviral Gene Therapy for Wiskott-Aldrich Syndrome RAWLINGS, DAVID SEATTLE CHILDREN'S HOSPITAL WA $715,509
Orphan Drug 2011 NCI 5R00CA129172-05 The Role of Bcl2L12 in the Genesis of Malignant Glioma STEGH, ALEXANDER NORTHWESTERN UNIVERSITY AT CHICAGO IL $241,530
Orphan Drug 2011 NHLBI 1R21HL106101-01 Cell-targeted drug delivery for the treatment of pulmonary arterial hypertension OKA, MASAHIKO UNIVERSITY OF SOUTH ALABAMA AL $230,625
Orphan Drug 2011 NCI 1R21CA155915-01 Bioactive compound modulation of epigenetic regulator Sp1/NFkB/miR network in AML LIU, SHUJUN OHIO STATE UNIVERSITY OH $199,013
Orphan Drug 2011 NCI 1R21CA156088-01 Targeted therapy of pancreatic cancer with in vivo radionuclide generator DADACHOVA, EKATERINA ALBERT EINSTEIN COL OF MED YESHIVA UNIV NY $180,525
Orphan Drug 2011 NCI 1P01CA155258-01 Integrative Oncogenomics of Multiple Myeloma MUNSHI, NIKHIL DANA-FARBER CANCER INSTITUTE MA $2,000,000
Orphan Drug 2011 NIAID 1R21AI092501-01 ROCK inhibitor suppression of GVHD with retention of GVL response IYENGAR, SUJATHA HACKENSACK UNIVERSITY MEDICAL CENTER NJ $264,150
Orphan Drug 2011 NIAMS 1R21AR060440-01 Evaluation of a Novel Anti-Resorptive Therapy for Osteogenesis Imperfecta COLLIN-OSDOBY, PATRICIA WASHINGTON UNIVERSITY MO $205,200
Orphan Drug 2011 NIAID 5R01AI033696-19 Mechanism Based Inhibition of M Tuberculosis Enzymes BLANCHARD, JOHN ALBERT EINSTEIN COL OF MED YESHIVA UNIV NY $660,690
Orphan Drug 2011 NINR 5F31NR012100-02 A novel treatment, TAT-HSP70, in attenuating lung injury in sepsis induced ARDS LYONS, MARY UNIVERSITY OF PENNSYLVANIA PA $34,661
Orphan Drug 2011 NIAID 5R01AI049151-08 Menaquinone biosynthesis:a drug target in Gram-positive bacteria CRICK, DEAN COLORADO STATE UNIVERSITY-FORT COLLINS CO $330,594
Orphan Drug 2011 NIMH 1R21MH092797-01 DEVELOPING PET AGENTS FOR IMAGING PHOSPHODIESTERASE 10A (PDE10A) TU, ZHUDE WASHINGTON UNIVERSITY MO $265,860
Orphan Drug 2011 NINDS 5R01NS059690-04 Molecular Chaperones and Small Molecules GESTWICKI, JASON UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $309,914
Orphan Drug 2011 NIAID 5R01AI082612-03 Firing up new treatments against Mycobacterium ulcerans disease (Buruli ulcer) GROSSET, JACQUES JOHNS HOPKINS UNIVERSITY MD $401,841
Orphan Drug 2011 NCI 5R01CA120893-05 Dendritic Cell-Brain Tumor Stem Cell Fusion Vaccines PLAUTZ, GREGORY CLEVELAND CLINIC LERNER COL/MED-CWRU OH $284,695
Orphan Drug 2011 NHLBI 5R01HL087997-04 Motivating Improved Self-Management Among Older Teens & Adults with CF RIEKERT, KRISTIN JOHNS HOPKINS UNIVERSITY MD $640,813
Orphan Drug 2011 NCI 5R01CA143204-02 The role of glutaminase 2, a novel p53 target gene in metabolism, in liver cancer FENG, ZHAOHUI UNIV OF MED/DENT NJ-R W JOHNSON MED SCH NJ $314,790
Orphan Drug 2011 NIAID 5R01AI082587-03 Small molecule protein-glycan inhib. as malaria transmission-blocking therapuetic DINGLASAN, RHOEL DAVID JOHNS HOPKINS UNIVERSITY MD $401,841
Orphan Drug 2011 NIAMS 1U01NS072323-01 Antisense oligonucleotide treatment for myotonic dystrophy THORNTON, CHARLES UNIVERSITY OF ROCHESTER NY $100,000
Orphan Drug 2011 NINDS 1U01NS072323-01 Antisense oligonucleotide treatment for myotonic dystrophy THORNTON, CHARLES UNIVERSITY OF ROCHESTER NY $454,543
Orphan Drug 2011 NCI 1R21CA155424-01 Enzyme-delivery scaffold technology for targeted cancer killing. LAVIE, ARNON UNIVERSITY OF ILLINOIS AT CHICAGO IL $231,069
Orphan Drug 2011 NCI 2R01CA072937-09 Interactions Between Cytotoxic and Antiangiogenic Drugs GALLO, JAMES MOUNT SINAI SCHOOL OF MEDICINE NY $229,022
Orphan Drug 2011 NINDS 5R01NS066582-07 Molecular Studies of Brain Malformations HU, HUAIYU UPSTATE MEDICAL UNIVERSITY NY $201,941
Orphan Drug 2011 NINDS 5R21NS067482-02 Development of a novel quinazoline compound for the treatment of spinal muscular DIDONATO, CHRISTINE CHILDREN'S MEMORIAL HOSPITAL (CHICAGO) IL $183,750
Orphan Drug 2011 NCI 1R21CA155479-01 Use of nanogels to target delivery of siRNA to cancer cells in mice MCDONALD, JOHN GEORGIA INSTITUTE OF TECHNOLOGY GA $240,470
Orphan Drug 2011 NCI 1R01CA156177-01 Targeted Photoactivable Nanocells: Image-based Drug Delivery and Dosimetry in GBM HASAN, TAYYABA MASSACHUSETTS GENERAL HOSPITAL MA $531,939
Orphan Drug 2011 NCI 5R01CA071540-14 Molecular Basis of Action of the Putative Oncogene BCL-6 BARDWELL, VIVIAN UNIVERSITY OF MINNESOTA TWIN CITIES MN $301,712
Orphan Drug 2011 NIAID 5F31AI081485-03 Targeting Trypanosoma brucei S-adenosylmethionine decarboxylase in Drug Discovery VELEZ, NAHIR UNIVERSITY OF TEXAS SW MED CTR/DALLAS TX $29,160
Orphan Drug 2011 NCI 5R01CA128864-04 Incorporating FLT3 inhibitors into AML treatment regimens LEVIS, MARK JOHNS HOPKINS UNIVERSITY MD $330,091
Orphan Drug 2011 NIAID 5R01AI070219-05 Design of Antituberculosis Agents that Target Siderophore Biosynthesis ALDRICH, COURTNEY UNIVERSITY OF MINNESOTA TWIN CITIES MN $336,353
Orphan Drug 2011 NIAID 1R15AI092315-01 Development of Piperidinols and Engelhardiones as Novel Antituberculosis Agents SUN, DIANQING UNIVERSITY OF HAWAII AT HILO HI $406,257
Orphan Drug 2011 NIAID 5R01AI085596-02 Mechanism of action and therapeutic targeting of properdin in complement injury SONG, WENCHAO UNIVERSITY OF PENNSYLVANIA PA $388,658
Orphan Drug 2011 NIAID 5R01AI056152-08 Study of gamma interferon agonists/mimetics JOHNSON, HOWARD UNIVERSITY OF FLORIDA FL $358,962
Orphan Drug 2011 NIAID 5R01AI064200-07 Heterocycle Cation Recognition of the DNA Minor Groove. WILSON, W DAVID GEORGIA STATE UNIVERSITY GA $357,638
Orphan Drug 2011 NCI 5R01CA078754-13 Mechanistic Studies on New Platinum Clinical Agents FARRELL, NICHOLAS VIRGINIA COMMONWEALTH UNIVERSITY VA $303,155
Orphan Drug 2011 NCI 5R01CA135380-03 Small-molecule Inhibition of the Interactions of the Urokinase Receptor: A Targe MEROUEH, SAMY INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS IN $247,971
Orphan Drug 2011 NCI 5R21CA149865-02 Targeting myeloid-derived suppressor cells for gastric cancer prevention TU, SHUIPING RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK NJ $162,451
Orphan Drug 2011 NIAID 5R01AI073564-04 T cell responses to chronic bacterial infection COOPER, ANDREA TRUDEAU INSTITUTE, INC. NY $452,178
Orphan Drug 2011 NIAID 2R37AI048793-11 Immunogenetic Mechanisms of Vaccine Response POLAND, GREGORY MAYO CLINIC MN $536,084
Orphan Drug 2011 NIA 1R15AG039008-01 Targeted nanoparticles for the detection and treatment of cerebral amyloid ERIKSEN, JASON UNIVERSITY OF HOUSTON TX $369,000
Orphan Drug 2011 NCI 5R21CA137418-02 Thermally Targeted Cell Cycle Inhibitors for the Treatment of Pancreatic Cancer RAUCHER, DRAZEN UNIVERSITY OF MISSISSIPPI MEDICAL CENTER MS $157,529
Orphan Drug 2011 NCI 5R01CA138723-02 Mechanism-Based Use of Chk1 Inhibitors in Pancreas Cancer MAYBAUM, JONATHAN UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $316,600
Orphan Drug 2011 NICHD 5F32HD060377-02 Activating Gene Expression with Antigene RNAs to Treat Genetic Diseases GAGNON, KEITH UNIVERSITY OF TEXAS SW MED CTR/DALLAS TX $51,326
Orphan Drug 2011 NIA 5R01AG019206-10 Synaptic toxicity of Huntington disease protein LI, XIAO-JIANG EMORY UNIVERSITY GA $292,496
Orphan Drug 2011 NIBIB 5R01EB002991-08 Biofunctional Polymers for Intracellular Drug Delivery STAYTON, PATRICK UNIVERSITY OF WASHINGTON WA $507,449
Orphan Drug 2011 NCI 5R01CA129132-04 Development of cambinol analogues as antilymphoma agents BEDALOV, ANTONIO FRED HUTCHINSON CANCER RESEARCH CENTER WA $354,244
Orphan Drug 2011 NIGMS 5R37GM052382-15 Structure and Mechanism of Protein Prenyltransferases BEESE, LORENA DUKE UNIVERSITY NC $370,656
Orphan Drug 2011 NIA 5P01AG021601-08 Novel Therapeutics for Prion Diseases PRUSINER, STANLEY UNIVERSITY OF CALIFORNIA SAN FRANCISCO CA $1,899,821
Orphan Drug 2011 NIAID 5R01AI041769-14 Cellular Mechanisms of PTLD in Transplant Recipients MARTINEZ, OLIVIA STANFORD UNIVERSITY CA $408,411
Orphan Drug 2011 NCI 5R03CA150048-02 Patterns of Care and Outcomes for Glioblastoma Patients DUBROW, ROBERT YALE UNIVERSITY CT $80,268
Orphan Drug 2011 NINDS 2R01NS037704-12A1 Molecular Markers as Predictors of Outcome in Gliomas POLLACK, IAN UNIVERSITY OF PITTSBURGH AT PITTSBURGH PA $344,337
Orphan Drug 2011 NCI 5U10CA098543-09 Children's Oncology Group Chair's Grant ADAMSON, PETER NATIONAL CHILDHOOD CANCER FOUNDATION CA $26,766,352
Orphan Drug 2011 NIGMS 5SC1GM082340-02 The Fulvene Approach to the Syntheses of Antitumor Agents ERDEN, IHSAN SAN FRANCISCO STATE UNIVERSITY CA $265,939
Orphan Drug 2011 NIMH 5R01MH085324-02 Synaptic Phenotype, Development, and Plasticity in the Fragile X Mouse COX, CHARLES UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN IL $401,852
Orphan Drug 2011 NIAID 1R01AI088075-01A1 Characterization of Pupylation in Mycobacterium tuberculosis DARWIN, KATERINA NEW YORK UNIVERSITY SCHOOL OF MEDICINE NY $380,250
Orphan Drug 2011 NCI 1R21CA155911-01 Targeted Radiotherapy with 90Y-BC8 Monclonal Antibody, Fludarabine and TBI Follow BENSINGER, WILLIAM FRED HUTCHINSON CANCER RESEARCH CENTER WA $352,615
Orphan Drug 2011 NIAID 2R01AI047798-11 PLASMEPSIN V FUNCTION IN MALARIA PARASITES GOLDBERG, DANIEL WASHINGTON UNIVERSITY MO $157,500
Orphan Drug 2011 NHLBI 5R01HL098416-03 Targeted replacement of defective lysosomal enzymes in the lung and brain MURO GALINDO, SILVIA UNIVERSITY OF MARYLAND COLLEGE PK CAMPUS MD $337,500
Orphan Drug 2011 NCI 5R01CA139059-03 Human engineered enzymes for L-Arg depletion chemotherapy GEORGIOU, GEORGE UNIVERSITY OF TEXAS AUSTIN TX $330,641
Orphan Drug 2011 NHLBI 5R01HL060644-12 Phosphorylation of ciliary target proteins SALATHE, MATTHIAS UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $382,500
Orphan Drug 2011 NHLBI 1R01HL098329-01A1 Fibrocytes in human pulmonary fibrosis MEHRAD, BORNA UNIVERSITY OF VIRGINIA CHARLOTTESVILLE VA $569,102
Orphan Drug 2011 NIAID 1R01AI087840-01A1 TB Membrane Transporters and Intrinsic Resistance PURDY, GEORGIANA OREGON HEALTH AND SCIENCE UNIVERSITY OR $394,855
Orphan Drug 2011 NIAID 5R01AI035272-19 Lipid storage and mobilization in M. tuberculosis as antilatency drugs targets KOLATTUKUDY, PAPPACHAN UNIVERSITY OF CENTRAL FLORIDA FL $366,827
Orphan Drug 2011 NINDS 5R01NS058815-02 Structure, Folding, and Misfolding of PMP22 SANDERS, CHARLES VANDERBILT UNIVERSITY TN $305,270
Orphan Drug 2011 NINDS 5F30NS066554-02 Cell-specific translational profiling in Huntington's Disease mouse models FENSTER, ROBERT WEILL MEDICAL COLLEGE OF CORNELL UNIV NY $46,800
Orphan Drug 2011 NINDS 5R01NS045209-08 c-Met/PTEN Interactions in Gliomas ABOUNADER, ROGER UNIVERSITY OF VIRGINIA CHARLOTTESVILLE VA $324,778
Orphan Drug 2011 NCI 1R01CA149109-01A1 The role of microRNAs in leukemic initiation and maintenance LU, JUN YALE UNIVERSITY CT $343,413
Orphan Drug 2011 NCI 2R01CA047148-24 Synthesis and Study of Natural and Non-natural Antiproliferative Agents MYERS, ANDREW HARVARD UNIVERSITY MA $699,182
Orphan Drug 2011 NINDS 1R21NS072793-01 The Histone Demethylase SMCX/JARED1C as a Therapeutic Target for Huntington's Dis THOMPSON, LESLIE UNIVERSITY OF CALIFORNIA IRVINE CA $229,500
Orphan Drug 2011 NCI 1R01CA148688-01A1 The ALK receptor tyrosine kinase as a therapeutic target in neuroblastoma GEORGE, RANI DANA-FARBER CANCER INSTITUTE MA $363,125
Orphan Drug 2011 NIAID 5R01AI082577-04 Validation and development of trypanosomal phosphodiesterase inhibitors for treat POLLASTRI, MICHAEL NORTHEASTERN UNIVERSITY MA $537,683
Orphan Drug 2011 NIMH 5R01MH087247-02 HIV-1 Associated Dementia: Concomitant Roles of Vpr and Cellular Factors AYYAVOO, VELPANDI UNIVERSITY OF PITTSBURGH AT PITTSBURGH PA $338,995
Orphan Drug 2011 NIAID 2R01AI009644-42 Biochemistry of Bacterial Cell Membranes NIKAIDO, HIROSHI UNIVERSITY OF CALIFORNIA BERKELEY CA $667,670
Orphan Drug 2011 NIAID 1R01AI087915-01A1 Host determinants of protection against tuberculosis in adolescents HANEKOM, WILLEM UNIVERSITY OF CAPE TOWN SO AFR $678,218
Orphan Drug 2011 NINDS 1U01NS069515-01A1 Development of an Oral Therapeutic Drug for Spinal and Bulbar Muscular Atrophy SHIH, CHARLES ANDROSCIENCE CORPORATION CA $862,195
Orphan Drug 2011 NEI 1R01EY020540-01A1 Molecular Mechanisms of Human Retinal Disease MARDON, GRAEME BAYLOR COLLEGE OF MEDICINE TX $439,740
Orphan Drug 2011 NICHD 5R01HD052731-04 Study of Fragile X Mental Retardation Protein in Synaptic Function and Plasticity HUBER, KIMBERLY UNIVERSITY OF TEXAS SW MED CTR/DALLAS TX $366,516
Orphan Drug 2011 NCI 5R01CA139444-07 Integrin-targeted siRNA delivery for therapeutic gene silencing in blood cancers SPRINGER, TIMOTHY IMMUNE DISEASE INSTITUTE, INC. MA $439,110
Orphan Drug 2011 NCI 5R01CA150547-02 Targeting Cdc42 in leukemia stem cells ZHENG, YI CHILDREN'S HOSPITAL MEDICAL CENTER CINCI OH $307,531
Orphan Drug 2011 NCI 5R01CA138720-02 Bone Marrow Transplantation for Hematologic Malignancies using Novel Radioimmunot PAGEL, JOHN FRED HUTCHINSON CANCER RESEARCH CENTER WA $354,244
Orphan Drug 2011 NCI 5R21CA138331-02 Novel Approaches for Structural Determination of Cancer Stem Cell Glycans HAKANSSON, KRISTINA UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $183,954
Orphan Drug 2011 NHLBI 5K25HL097246-02 Mechanisms of Microvascular Response to Arterial Stiffening and Flow Pulsatility TAN, WEI UNIVERSITY OF COLORADO AT BOULDER CO $145,800
Orphan Drug 2011 NHLBI 5R01HL064024-10 Mechanism and therapy for arteriovenous malformation OH, SUK UNIVERSITY OF FLORIDA FL $385,589
Orphan Drug 2011 NCI 5R01CA138636-02 BETR Therapy for Herpesvirus-Associated Tumors POMPER, MARTIN JOHNS HOPKINS UNIVERSITY MD $553,505
Orphan Drug 2011 NIDCR 5R01DE019126-03 Biomarkers to Guide Treatment and Improve Survival in Oral/Oropharyngeal Cancer CAREY, THOMAS UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $333,825
Orphan Drug 2011 NCI 1R21CA149939-01A1 Dual Targeting of MEK and EGFR Signaling Pathways in Advanced Pancreatic Cancer KO, ANDREW UNIVERSITY OF CALIFORNIA SAN FRANCISCO CA $310,267
Orphan Drug 2011 NIDDK 5R01DK066448-08 RETROVIRAL VECTOR-MEDIATED LIVER GENE THERAPY FOR MPS I PONDER, KATHERINE WASHINGTON UNIVERSITY MO $327,539
Orphan Drug 2011 NHLBI 5R37HL048129-17 Role and Regulation of Sodium, Potasium ATPase in Lung SZNAJDER, JACOB NORTHWESTERN UNIVERSITY AT CHICAGO IL $379,471
Orphan Drug 2011 NICHD 5R01HD064667-02 Retinoid-Related Genes in Diaphragm and Cardiac Development SCOTT, DARYL BAYLOR COLLEGE OF MEDICINE TX $305,772
Orphan Drug 2011 NHLBI 5R01HL038650-22 Flavin-Containing Monooxygenase in Lung WILLIAMS, DAVID OREGON STATE UNIVERSITY OR $359,770
Orphan Drug 2011 NCI 1P01CA142536-01A1 8358 Olig2 Antagonists for Targeted Therapy of Pediatric Astrocytomas STILES, CHARLES DANA-FARBER CANCER INSTITUTE MA $398,201
Orphan Drug 2011 NIAID 5R01AI076183-09 Structural and Functional Studies of gp42 and HLA Class II in EBV Entry LONGNECKER, RICHARD NORTHWESTERN UNIVERSITY AT CHICAGO IL $400,947
Orphan Drug 2011 NIAID 5R01AI065622-06 Redox Balance & Drug Development in Schistosoma mansoni WILLIAMS, DAVID RUSH UNIVERSITY MEDICAL CENTER IL $260,401
Orphan Drug 2011 NCI 7R01CA140323-02 Exploiting Biological Networks to Improve Clinical Treatment of Ovarian Cancer GODWIN, ANDREW UNIVERSITY OF KANSAS MEDICAL CENTER KS $366,458
Orphan Drug 2011 NIAID 5R01AI051305-09 Genetic Basis of Severe Malarial Anemia PERKINS, DOUGLAS UNIVERSITY OF NEW MEXICO NM $533,334
Orphan Drug 2011 NCI 5U10CA021661-35 Radiation Therapy Oncology Group CURRAN, WALTER AMERICAN COLLEGE OF RADIOLOGY VA $10,630,221
Orphan Drug 2011 NIAID 5R01AI074057-04 Optimization of HPMPA and CDV Analogs for Treatment of Smallpox HOSTETLER, KARL VETERANS MEDICAL RESEARCH FDN/SAN DIEGO CA $525,526
Orphan Drug 2011 NEI 5R01EY005798-23 cGMP and Photoreceptor Function COTE, RICK UNIVERSITY OF NEW HAMPSHIRE NH $343,950
Orphan Drug 2011 NIGMS 5F32GM093510-02 Investigating the shikimate pathway in Plasmodium falciparum DERBYSHIRE, EMILY HARVARD UNIVERSITY (MEDICAL SCHOOL) MA $51,326
Orphan Drug 2011 NCI 5R01CA057683-18 Toward a molecular classification of human gliomas LOUIS, DAVID MASSACHUSETTS GENERAL HOSPITAL MA $301,819
Orphan Drug 2011 NIAID 5R01AI070285-05 Structural studies of the M. tuberculosis proteasome and proteasomal ATPase LI, HUILIN BROOKHAVEN SCIENCE ASSOC-BROOKHAVEN LAB NY $365,612
Orphan Drug 2011 NCI 2K24CA111717-06A1 Targeting Epigenomics in Myeloid Neoplasms GORE, STEVEN JOHNS HOPKINS UNIVERSITY MD $196,885
Orphan Drug 2011 NCI 4R37CA090426-11 Metabolism of Carcinogens and Drugs by Human P450s GUENGERICH, F VANDERBILT UNIVERSITY TN $364,770
Orphan Drug 2011 NIDCD 5R01DC009246-03 Deciphering the Usher I protein interactome using a genetic approach ZHENG, QING CASE WESTERN RESERVE UNIVERSITY OH $319,720
Orphan Drug 2011 NINDS 5R44NS060199-04 Refinement of lead compounds to modulate water permeability through AQP4 PELLETIER, MARC AEROMICS, LLC OH $749,969
Orphan Drug 2011 NIAID 5K23AI080842-03 PK/PD Issues in the Use of New Therapies for the Treatment of Tuberculosis DOOLEY, KELLY JOHNS HOPKINS UNIVERSITY MD $134,325
Orphan Drug 2011 NHLBI 5R01HL066565-10 Mechanisms of Cardiopulmonary Gene Transfer DIAMOND, SCOTT UNIVERSITY OF PENNSYLVANIA PA $307,803
Orphan Drug 2011 NCI 1U01CA140207-01A2 Quantitative Volume and Density Response Assessment: Sarcoma and HCC as a Model SCHWARTZ, LAWRENCE COLUMBIA UNIVERSITY HEALTH SCIENCES NY $656,025
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