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RCDC

Project Listing by Category


Back to Estimates of Funding for Various Research, Condition, and Disease Categories (RCDC) Click the column headings to sort project listings.
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CategoryFYFunding ICProject NumberSub Project #Project TitlePI NameOrg NameState / CountryAmount
ALS 2011 NIDA 5R44DA023737-03 New Drugs to Enhance Endocannabinoid Responses for Treating Excitotoxicity, Phase GOLIK, JERZY MAKSCIENTIFIC, LLC MA $516,628
ALS 2011 NIEHS 1K99ES019186-01 Glutathione in mitochondrial dysfunction and disease progression in ALS-models VARGAS, MARCELO UNIVERSITY OF WISCONSIN MADISON WI $90,000
ALS 2011 NINDS 5R00NS062089-04 Mechanism of SOD1-linked ALS studied in C elegans and mouse models WANG, JIOU JOHNS HOPKINS UNIVERSITY MD $244,450
ALS 2011 NIGMS 5R01GM064631-09 Structure/Function of Mn and Fe Superoxide Dismutases and Related Enzymes BRUNOLD, THOMAS UNIVERSITY OF WISCONSIN MADISON WI $245,682
ALS 2011 NINDS 5R01NS061920-03 Calcium Permeable AMPA Receptors: Signaling, Toxicity and Control ZIFF, EDWARD NEW YORK UNIVERSITY SCHOOL OF MEDICINE NY $363,366
ALS 2011 NINDS 5R01NS055315-04 Mechanisms of SOD1 toxicity in ALS ELLIOTT, JEFFREY UNIVERSITY OF TEXAS SW MED CTR/DALLAS TX $302,913
ALS 2011 NINDS 5F30NS067938-02 Defining the Role of TDP-43 in Neurodegenerative Disease Pathways WEGORZEWSKA, IGA WASHINGTON UNIVERSITY MO $46,800
ALS 2011 NINDS 5R01NS062055-03 Defects of mitochondrial dynamics in ALS MANFREDI, GIOVANNI WEILL MEDICAL COLLEGE OF CORNELL UNIV NY $359,120
ALS 2011 NINDS 5R01NS065895-02 Skeletal Muscle Mechanisms of Disease in ALS MARTIN, LEE JOHNS HOPKINS UNIVERSITY MD $351,575
ALS 2011 NINDS 5R21NS069946-02 Exploiting Trans-Suppression to Arrest hSOD Aggregation in ALS KWON, INCHAN UNIVERSITY OF VIRGINIA CHARLOTTESVILLE VA $179,280
ALS 2011 NINDS 5R01NS055746-05 Mechanisms of motor neuron toxicity in Kennedy Disease LIEBERMAN, ANDREW UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $341,384
ALS 2011 NIDCD 5R01DC009834-03 Translational refinement of adaptive communication system for locked-in patients FRIED-OKEN, MELANIE OREGON HEALTH AND SCIENCE UNIVERSITY OR $698,439
ALS 2011 NINDS 5R21NS067153-02 Using CD4+ T cells as a candidate therapy to slow disease progression in ALS APPEL, STANLEY METHODIST HOSPITAL RESEARCH INSTITUTE TX $192,500
ALS 2011 NINDS 1R21NS072182-01 Pre-clinical testing of necrostatin as a potential small molecule for the treatme PRZEDBORSKI, SERGE COLUMBIA UNIVERSITY HEALTH SCIENCES NY $240,750
ALS 2011 NINDS 5R01NS058888-04 Ca2+ mishandling and ischemia-vulnerability in fALS model motor terminals DAVID, GAVRIEL UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $262,395
ALS 2011 NINDS 1R21NS072749-01 Small Molecule Probes for TAR DNA Binding Protein 43_TDP-43 REITZ, ALLEN ALS BIOPHARMA, LLC PA $189,000
ALS 2011 NINDS 5R01NS045062-08 MR and BL Tracking of Stem/Progenitor Cells in the CNS BULTE, JEFF JOHNS HOPKINS UNIVERSITY MD $418,690
ALS 2011 NINDS 1K01NS069616-01A1 A New Approach to ALS MITCHELL, CASSIE GEORGIA INSTITUTE OF TECHNOLOGY GA $128,293
ALS 2011 NIGMS 5R01GM082956-02 Mechanism and targets of Sen1-dependent RNA polymerase II termination BROW, DAVID UNIVERSITY OF WISCONSIN MADISON WI $276,409
ALS 2011 NINDS 5R01NS064488-03 Mechanisms of Mutant SOD 1-Mediated Mitochondria Toxicity in the Spinal Cord of A TROTTI, DAVIDE THOMAS JEFFERSON UNIVERSITY PA $331,209
ALS 2011 NINDS 5R01NS042269-07 Proinflammatory enzymes in amytrophic lateral sclerosis PRZEDBORSKI, SERGE COLUMBIA UNIVERSITY HEALTH SCIENCES NY $466,118
ALS 2011 NINDS 5R01NS065317-03 Molecular basis of TDP-43 proteinopathies: disease models and mechanisms GITLER, AARON UNIVERSITY OF PENNSYLVANIA PA $332,935
ALS 2011 NIAMS 5R01AR057404-02 Ca Signaling in Progression of Amyotrophic Lateral Sclerosis in Skeletal Muscle ZHOU, JINGSONG RUSH UNIVERSITY MEDICAL CENTER IL $321,192
ALS 2011 NINDS 5R01NS064133-04 The Role of HuR in mutant SOD1 dysregulation of VEGF mRNA Processing KING, PETER UNIVERSITY OF ALABAMA AT BIRMINGHAM AL $289,168
ALS 2011 NINDS 5K08NS057664-04 Dysregulation of VEGF RNA Stability in Amyotrophic Lateral Sclerosis LU, LIANG UNIVERSITY OF ALABAMA AT BIRMINGHAM AL $145,800
ALS 2011 NINDS 5R01NS069669-02 DEFINING THE MECHANISM OF TDP-43 RELATED NEURODEGENERATION BALOH, ROBERT WASHINGTON UNIVERSITY MO $325,850
ALS 2011 NINDS 5R21NS066175-02 Single chain Fragments of variable regions in the treatment of Familial ALS ROOS, RAYMOND UNIVERSITY OF CHICAGO IL $195,625
ALS 2011 NINDS 5R01NS062849-03 Fate specification of corticospinal neurons by cell autonomous signaling ARLOTTA, PAOLA MASSACHUSETTS GENERAL HOSPITAL MA $235,736
ALS 2011 NINDS 5R21NS066108-02 The Role of Stress Granules in the Pathophysiology of TDP-43 WOLOZIN, BENJAMIN BOSTON UNIVERSITY MEDICAL CAMPUS MA $232,750
ALS 2011 NINDS 5R01NS054154-06 Genetics of the Neuromuscular Junction: Mechanisms and Disease Models BURGESS, ROBERT JACKSON LABORATORY ME $459,784
ALS 2011 NINDS 5R01NS054739-04 Transciption Factor Codes, Guidance Receptors and Motor Axon Guidance BASHAW, GREG UNIVERSITY OF PENNSYLVANIA PA $308,700
ALS 2011 NIGMS 5R01GM080742-05 Protein misfolding and aggregation DOKHOLYAN, NIKOLAY UNIVERSITY OF NORTH CAROLINA CHAPEL HILL NC $256,724
ALS 2011 NINDS 5R01NS065048-03 Regulation of Sensory-Motor Connectivity by Semaphorin-Plexin Signaling YOSHIDA, YUTAKA CHILDREN'S HOSPITAL MEDICAL CENTER CINCI OH $321,563
ALS 2011 NINDS 5R21NS066129-02 Novel Hsp90 Inhibitors: Proof-of-Principle for Treatment of Motor Neuron Diseases CHEN, RUIHONG NEXGENIX PHARMACEUTICALS, INC. NY $142,280
ALS 2011 NINDS 5R01NS059708-04 Transgenic models of ALS caused by VAPB mutation XU, ZUOSHANG UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $348,359
ALS 2011 NINDS 5R01NS065847-02 Characterization of KIFAP3, a Modifier of Survival in Sporadic ALS LANDERS, JOHN UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $352,647
ALS 2011 NINDS 5F31NS068165-02 Contribution of AMPK to motor neuron disease LIM, MARIA UNIVERSITY OF PENNSYLVANIA PA $41,800
ALS 2011 NCI 1R43CA156781-01 Riluzole Prodrugs for Melanoma and ALS REITZ, ALLEN FOX CHASE CHEMICAL DIVERSITY CENTER, INC PA $336,255
ALS 2011 NINDS 1R41NS070401-01A1 Developing UPR Modulators as Novel Therapeutics for Neurodegeneration BACKES, BRADLEY METAFOLD THERAPEUTICS, INC. CA $196,688
ALS 2011 NINDS 5R01NS056422-05 Role of Fas death receptor signaling in motor neuron degeneration HENDERSON, CHRISTOPHER COLUMBIA UNIVERSITY HEALTH SCIENCES NY $345,144
ALS 2011 NINDS 1F31NS073435-01 The impact of post-translational modification on SOD1 aggregation in ALS REDLER, RACHEL UNIVERSITY OF NORTH CAROLINA CHAPEL HILL NC $30,094
ALS 2011 NINDS 1F31NS070431-01A1 Defining the role for Gle1 in the fetal lethal motor neuron disease LCCS1 FOLKMANN, ANDREW VANDERBILT UNIVERSITY TN $26,439
ALS 2011 NINDS 5R01NS065263-03 Structural Consequences of ALS-related Modifications of SOD1 AGAR, JEFFREY BRANDEIS UNIVERSITY MA $338,713
ALS 2011 NIA 5R01AG026251-04 Progranulin, TDP-43 and Cell Death PETRUCELLI, LEONARD MAYO CLINIC JACKSONVILLE FL $301,480
ALS 2011 NINDS 1F32NS068029-01A1 Skeletal Muscle Mitochondrial Dysfunction and Motor Unit Number in Sporadic ALS TOWSE, THEODORE VANDERBILT UNIVERSITY TN $55,742
ALS 2011 NINDS 5R01NS040014-10 Mechanisms & Mouse Models of Amyotrophic Lateral Sclerosis WONG, PHILIP JOHNS HOPKINS UNIVERSITY MD $351,575
ALS 2011 NINDS 5R37NS027036-24 Neurofilaments, SOD1 and Motor Neuron Diseases CLEVELAND, DON LUDWIG INSTITUTE FOR CANCER RESEARCH CA $602,973
ALS 2011 NINDS 5R01NS040819-09 Mechanisms of Protection and Pathogenesis in Amyotrophic Lateral Sclerosis Mice CROW, JOHN UNIVERSITY OF ARKANSAS MED SCIS LTL ROCK AR $365,096
ALS 2011 NIEHS 5R01ES016348-03 Multicenter ALS Cohort Study of Oxidative Stress and Disease Progression MITSUMOTO, HIROSHI COLUMBIA UNIVERSITY HEALTH SCIENCES NY $648,384
ALS 2011 NINDS 5K23NS055200-05 Pilot Placebo-Controlled Trial of Early Noninvasive Ventilation for ALS GRUIS, KIRSTEN UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $173,340
ALS 2011 NINDS 5R03NS070050-02 CD4+CD25+ Treg cells regulate microglia and provide neuroprotection in ALS ZHAO, WEIHUA METHODIST HOSPITAL RESEARCH INSTITUTE TX $75,460
ALS 2011 NIGMS 5R01GM054836-14 Folding and Aggregation Mechanisms of Human Cu,Zn Superoxide Dismutase MATTHEWS, C UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $332,208
ALS 2011 NINDS 5F30NS068108-02 ALS-associated TDP-43 Aggregation: A Drosophila Model and A Role for Autophagy HANSON, KEITH UNIVERSITY OF WISCONSIN MADISON WI $34,096
ALS 2011 NINDS 5R21NS071256-02 Stabilizing fALS SOD1 Variants by Crosslinking Subunits AGAR, JEFFREY BRANDEIS UNIVERSITY MA $193,550
ALS 2011 NINDS 5R01NS058628-04 Superoxide Dismutase, Peroxynitrite and ALS BECKMAN, JOSEPH OREGON STATE UNIVERSITY OR $313,416
ALS 2011 NINDS 5R01NS064131-03 Developing neuroprotective strategies for proteinopathy: a comparative modeling KRAEMER, BRIAN SEATTLE INST FOR BIOMEDICAL/CLINICAL RES WA $261,817
ALS 2011 NINDS 5R01NS060698-04 Mechanistic analysis of axonal transport defects in motor neuron degenerative dis HOLZBAUR, ERIKA UNIVERSITY OF PENNSYLVANIA PA $337,641
ALS 2011 NINDS 5K08NS062890-04 A Drosophila model of motor neuron disease using mutations in P150 / Dynactin. LLOYD, THOMAS JOHNS HOPKINS UNIVERSITY MD $175,635
ALS 2011 NINDS 5R01NS061867-03 Peptide and Protein Biomarkers for Amyotrophic Lateral Sclerosis (ALS) BOWSER, ROBERT UNIVERSITY OF PITTSBURGH AT PITTSBURGH PA $324,778
ALS 2011 NINDS 5R01NS069212-02 Motor Neuron Disease in Mouse Models of ALS: Where Does The End Begin MILLIGAN, CAROL WAKE FOREST UNIVERSITY HEALTH SCIENCES NC $317,275
ALS 2011 NINDS 5F30NS065635-03 Mechanisms underlying development and resistance of ALS of specific motor pools KAPLAN, ARTEM COLUMBIA UNIVERSITY HEALTH SCIENCES NY $46,800
ALS 2011 NINDS 1R01NS073873-01 Identification of genes causative for familial ALS gene using exome sequencing LANDERS, JOHN UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $359,844
ALS 2011 NINDS 1R21NS074121-01 Pathologically modified TDP-43 in neurodegenerative diseases GENDRON, TANIA MAYO CLINIC JACKSONVILLE FL $232,500
ALS 2011 NIDCD 5R01DC004689-10 Therapeutic Approaches to Dysarthria: Acoustic and Perceptual Correlates TJADEN, KRIS STATE UNIVERSITY OF NEW YORK AT BUFFALO NY $248,495
ALS 2011 NINDS 5R01NS058980-04 Genetics of Gene Expression and Gene Mapping for Amytrophic Lateral Sclerosis OPHOFF, ROEL UNIVERSITY OF CALIFORNIA LOS ANGELES CA $310,415
ALS 2011 NINDS 5U01NS049640-07 Clinical Trial of Ceftriaxone in Subjects with ALS CUDKOWICZ, MERIT MASSACHUSETTS GENERAL HOSPITAL MA $6,688,079
ALS 2011 NIEHS 5R01ES008089-13 The Nrf2-ARE Pathway in Amyotrophic Lateral Sclerosis JOHNSON, JEFFREY UNIVERSITY OF WISCONSIN MADISON WI $360,633
ALS 2011 NINDS 5R01NS067206-02 Investigation of post-translational modifications in WT SOD1 in sporadic ALS BOSCO, DARYL UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $352,647
ALS 2011 NINDS 2R01NS051488-06 SOD1/Bcl-2 induced mitochondrial dysfunction in FALS and SALS. PASINELLI, PIERA THOMAS JEFFERSON UNIVERSITY PA $402,324
ALS 2011 NINDS 5R01NS064492-03 Role of Potent Trophic Factors on Glia and Motor Neurons in ALS KASPAR, BRIAN RESEARCH INST NATIONWIDE CHILDREN'S HOSP OH $308,700
ALS 2011 NINDS 1R01NS069700-01A1 New Insights into Motor Neuron Disease FINK, JOHN UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $315,958
ALS 2011 NINDS 5R01NS064253-05 Pathogenesis of Neurodegenerative Diseases Caused by Mutations in Senataxin NAGY, PETER COLUMBIA UNIVERSITY HEALTH SCIENCES NY $345,144
ALS 2011 NINDS 1R21NS072882-01A1 Gene Expression in Motor Neurons with Differential Susceptibility to ALS GOULD, ELIZABETH PRINCETON UNIVERSITY NJ $191,902
ALS 2011 NINDS 1R21NS071186-01A1 Using Drosophila as a model to understand TDP-43 function in ALS MORTON, DAVID OREGON HEALTH AND SCIENCE UNIVERSITY OR $217,518
ALS 2011 NINDS 5R21NS067572-02 Genetic modifiers of motor neuron degeneration TIBBETTS, RANDAL UNIVERSITY OF WISCONSIN MADISON WI $181,913
ALS 2011 NINDS 1R21NS071348-01A1 Membrane properties of neurons controlling jaw function in a mouse model of ALS CHANDLER, SCOTT UNIVERSITY OF CALIFORNIA LOS ANGELES CA $231,000
ALS 2011 NIGMS 5R01GM094384-02 Neuronal RNA processing defects in ALS4 caused by SETX mutations BENNETT, CRAIG UNIVERSITY OF CALIFORNIA SAN DIEGO CA $296,159
ALS 2011 NINDS 5R01NS060874-04 Brain Metabolic Imaging in Amyotrophic Lateral Sclerosis GOVIND, VARAN UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $295,195
ALS 2011 NINDS 5R01NS067247-03 The Role of Toxic Ion Channels in ALS Pathogenesis ALLEN, MICHAEL UNIVERSITY OF CHICAGO IL $334,425
ALS 2011 NINDS 5R01NS062766-04 Regulation of mitochondrial oxidative stress by Bcl-2 family proteins LINSEMAN, DANIEL UNIVERSITY OF DENVER (COLORADO SEMINARY) CO $292,301
ALS 2011 NIDCD 1F31DC010093-01A2 Framework for a perceptually-driven taxonomy of dysarthric speech LANSFORD, KAITLIN ARIZONA STATE UNIVERSITY-TEMPE CAMPUS AZ $31,110
ALS 2011 NINDS 2R01NS052325-06A1 Trophic Factor Signaling and Motor Neuron Death KALB, ROBERT CHILDRENS HOSPITAL OF PHILADELPHIA PA $366,406
ALS 2011 NINDS 1R43NS074671-01 Novel RNAi therapy for ALS and other Neurodegenerative Disorders KHVOROVA, ANASTASIA RXI PHARMACEUTICALS CORPORATION MA $304,559
ALS 2011 NINDS 5R21NS072588-02 Genetic Mechanisms of Motor Neuron Degeneration KIM, MICHAEL UNIVERSITY OF MIAMI SCHOOL OF MEDICINE FL $187,425
ALS 2011 NIA 1F30AG039238-01A1 Modifiers of Age of Onset in ALS Studied Using Patient iPS-derived Motor Neurons OAKLEY, DEREK COLUMBIA UNIVERSITY HEALTH SCIENCES NY $46,800
ALS 2011 NINDS 1F31NS074848-01 Defining the role of Ataxin-2 in ALS and TDP-43 proteinopathies HART, MICHAEL UNIVERSITY OF PENNSYLVANIA PA $41,800
ALS 2011 NIA 1F32AG038259-01A2 Defining Mechanisms of TDP-43 Ubiquitination for Quality Control and Aggregation DAMMER, ERIC EMORY UNIVERSITY GA $51,326
ALS 2011 NIDCD 1F31DC011689-01 Associations between laryngeal and cough dysfunction in bulbar amyotrophic latera BRITTON, DEANNA UNIVERSITY OF WASHINGTON WA $34,961
ALS 2011 NINDS 1F32NS073269-01A1 Roles for TDP-43 and FUS in ALS Using Motor Neurons from Embryonic Stem Cells DITSWORTH, DARA LUDWIG INSTITUTE FOR CANCER RESEARCH CA $51,326
ALS 2011 NINDS 5F32NS066675-02 Local Circuit Properties of Mouse Corticospinal Neurons SHEETS, PATRICK NORTHWESTERN UNIVERSITY AT CHICAGO IL $53,042
ALS 2011 NIDCD 5R01DC009890-03 Bulbar Motor Deterioration in ALS GREEN, JORDAN UNIVERSITY OF NEBRASKA LINCOLN NE $462,837
ALS 2011 NINDS 5R21NS072696-02 Developing in vivo and in vitro Models for ALS Caused by Mutant FUS XIA, XUGANG THOMAS JEFFERSON UNIVERSITY PA $227,850
ALS 2011 NICHD 1U01NS074601-01 Small Molecule Modulators of the Glutamate Transporter for Treatment of ALS GLICKSMAN, MARCIE BRIGHAM AND WOMEN'S HOSPITAL MA $162,278
ALS 2011 NIMH 1U01NS074601-01 Small Molecule Modulators of the Glutamate Transporter for Treatment of ALS GLICKSMAN, MARCIE BRIGHAM AND WOMEN'S HOSPITAL MA $71,228
ALS 2011 NINDS 1R13NS074853-01 NIH ALS Conference: Clinical Research to Find the Pathogenesis and Cause of ALS MITSUMOTO, HIROSHI COLUMBIA UNIVERSITY HEALTH SCIENCES NY $15,000
ALS 2011 OD 1R13NS074853-01 NIH ALS Conference: Clinical Research to Find the Pathogenesis and Cause of ALS MITSUMOTO, HIROSHI COLUMBIA UNIVERSITY HEALTH SCIENCES NY $10,000
ALS 2011 NINDS 5R01NS072113-02 Pathogenic Mechanisms of ALS-Linked TDP Gene Mutation XIA, XUGANG THOMAS JEFFERSON UNIVERSITY PA $332,281
ALS 2011 NINDS 5R21NS072561-02 TDP-43 and FUS RNA pathways in motor neuron degeneration MOURELATOS, ZISSIMOS UNIVERSITY OF PENNSYLVANIA PA $196,000
ALS 2011 NINDS 5R21NS072675-02 A Spontaneous Mouse Model of Motor Neuron Disease BURGESS, ROBERT JACKSON LABORATORY ME $264,159
ALS 2011 NINDS 1R01NS074886-01 Role of ABC efflux transporters in ALS TROTTI, DAVIDE THOMAS JEFFERSON UNIVERSITY PA $338,843
ALS 2011 NINDS 5U01NS052225-06 Development of New Therapeutics for Amyotrophic Lateral Sclerosis BROWN, ROBERT UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $1
ALS 2011 NINDS 5K08NS067282-02 Functional consequences of HSPB1 mutations that result in motor neuron disease KOLB, STEPHEN OHIO STATE UNIVERSITY OH $168,199
ALS 2011 NINDS 5R01NS041648-12 MODELS OF SBMA MOTOR NEURON DEGENERATION LA SPADA, ALBERT UNIVERSITY OF CALIFORNIA SAN DIEGO CA $331,531
ALS 2011 NIEHS 5R01ES019188-02 Population-Based Study of Environmental Risk Factors for ALS WEISSKOPF, MARC HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) MA $386,511
ALS 2011 NIA 5P01AG032953-02 TDP-43 Proteinopathies in ALS-Dementia LEE, VIRGINIA UNIVERSITY OF PENNSYLVANIA PA $782,355
ALS 2011 NINDS 5P01AG032953-02 TDP-43 Proteinopathies in ALS-Dementia LEE, VIRGINIA UNIVERSITY OF PENNSYLVANIA PA $384,480
ALS 2011 NIGMS 5R01GM039345-15 Superoxide Dismutase Structures and Lou Gehrigs Disease TAINER, JOHN SCRIPPS RESEARCH INSTITUTE CA $357,202
ALS 2011 NINDS 5R21NS070142-02 Transgenic Study of ALS-Linked CCS Mutations DENG, HAN-XIANG NORTHWESTERN UNIVERSITY AT CHICAGO IL $186,813
ALS 2011 NINDS 1K08NS075094-01 NEXT-GENERATION SEQUENCING APPROACHES FOR NOVEL GENE DISCOVERY IN ALS HARMS, MATTHEW WASHINGTON UNIVERSITY MO $157,414
ALS 2011 NINDS 1K99NS075216-01 mRNA Targets for TDP-43 and FUS/TLS: Identifying Key RNA-Processing Errors in ALS POLYMENIDOU, MAGDALINI LUDWIG INSTITUTE FOR CANCER RESEARCH CA $91,044
ALS 2011 NINDS 1K08NS072233-01A1 Elucidating the Mechanisms Underlying Mutant TDP43-induced Neurodegeneration BARMADA, SAMI J. DAVID GLADSTONE INSTITUTES CA $175,448
ALS 2011 NINDS 1R43NS076194-01 Oligonucleotides that Modulate AMPA Receptor Alternative Splicing as Drug Candida LUTZ, GORDON LIFESPLICE PHARMA, LLC PA $315,001
ALS 2011 NINDS 1F31NS073398-01A1 Brain Delivery of Nanoformulated Superoxide Dismutase ROSENBAUGH, ERIN UNIVERSITY OF NEBRASKA MEDICAL CENTER NE $31,896
ALS 2011 NINDS 1F31NS073351-01A1 Toxicity of a SUMOylated Fragment of the Glial Glutamate Transporter EAAT2 in ALS FORAN, EMILY THOMAS JEFFERSON UNIVERSITY PA $41,800
ALS 2011 NINDS 1F31NS076326-01 Identifying excitotoxic mechanisms in a C. elegans model of axon destabilization BARBAGALLO, BELINDA UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $28,314
ALS 2011 NINDS 5R01NS036761-12 Peroxynitrite, nitrotyrosine and HSP90 in neuronal death ESTEVEZ, ALVARO UNIVERSITY OF CENTRAL FLORIDA FL $310,844
ALS 2011 NINDS 5R01NS065237-03 Angiogenin in ALS Pathobiology and Therapy HU, GUO-FU TUFTS MEDICAL CENTER MA $363,365
ALS 2011 NINDS 1R01NS077284-01 Role of FUS in ALS ZHU, HAINING UNIVERSITY OF KENTUCKY KY $324,844
ALS 2011 NINDS 5P01NS057778-05 0001 Respiratory Plasticity in the SOD1g93a Rat MITCHELL, GORDON UNIVERSITY OF WISCONSIN MADISON WI $291,201
ALS 2011 NINDS 5P01NS057778-05 0002 Astrocytes Producting Growth Factors for ALS SVENDSEN, CLIVE UNIVERSITY OF WISCONSIN MADISON WI $277,858
ALS 2011 NINDS 5P01NS057778-05 0003 Replacement of Motor Neurons and Astrocytes in ALS Using Human Embryonic Stem Cel ZHANG, SU-CHUN UNIVERSITY OF WISCONSIN MADISON WI $266,979
ALS 2011 NINDS 1R01NS074324-01A1 Neurodegeneration and Proteotoxicity Dissected in C. elegans and Mammals WANG, JIOU JOHNS HOPKINS UNIVERSITY MD $322,875
ALS 2011 NINDS 1R01NS072494-01A1 Pooling of Prospective Studies of Diet, Lifestyle and ALS O'REILLY, EILIS HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) MA $176,641
ALS 2011 NINDS 1R01NS073776-01A1 FUS/TLS GAIN AND LOSS OF FUNCTION IN ALS: ANIMAL AND CELLULAR MODELS OF DISEASE SHNEIDER, NEIL COLUMBIA UNIVERSITY HEALTH SCIENCES NY $342,388
ALS 2011 NINDS 1R01NS073660-01A1 Ataxin-2 as a genetic risk factor for ALS: New insights into neurodegeneration BONINI, NANCY UNIVERSITY OF PENNSYLVANIA PA $342,457
ALS 2011 NINDS 1R21NS073679-01A1 Identification of compounds that inhibit aggregation and toxicity of TDP-43 WOLOZIN, BENJAMIN BOSTON UNIVERSITY MEDICAL CAMPUS MA $230,110
ALS 2011 NINDS 5P01NS049134-07 7760 Project 1 VALENTINE, JOAN UNIVERSITY OF CALIFORNIA LOS ANGELES CA $225,987
ALS 2011 NINDS 5P01NS049134-07 7761 Project 2 WIEDAU-PAZOS, MARTINA UNIVERSITY OF CALIFORNIA LOS ANGELES CA $231,242
ALS 2011 NINDS 5P01NS049134-07 7766 Protein and metal analysis core WHITELEGGE, JULIAN UNIVERSITY OF CALIFORNIA LOS ANGELES CA $213,374
ALS 2011 NINDS 1F31NS074620-01A1 Cytoprotective mechanism against misfolded SOD1-induced toxicity YUNG, CHERYL EMORY UNIVERSITY GA $30,480
ALS 2011 NINDS 1F31NS077806-01 Perivascular astrocyte morphology during motor neuron degeneration LORENZINI, ILEANA JOHNS HOPKINS UNIVERSITY MD $25,800
ALS 2011 NINDS 1R01NS077863-01 Electrical and mechanical properties of motor units in a mouse model of ALS HECKMAN, CHARLES NORTHWESTERN UNIVERSITY AT CHICAGO IL $534,780
ALS 2011 NCCAM 5P01AT002034-09 7042 CAM Antioxidants and ALS BECKMAN, JOSEPH OREGON STATE UNIVERSITY OR $223,338
ALS 2011 OD 5P01AT002034-09 7042 CAM Antioxidants and ALS BECKMAN, JOSEPH OREGON STATE UNIVERSITY OR $75,297
ALS 2011 NIA 5P01AG019724-10 0004 CLINICAL CRITERIA MILLER, BRUCE UNIVERSITY OF CALIFORNIA SAN FRANCISCO CA $282,767
ALS 2011 NIA 5P01AG019724-10 9001 CLINICAL AND ADMINISTRATIVE MILLER, BRUCE UNIVERSITY OF CALIFORNIA SAN FRANCISCO CA $588,995
ALS 2011 NINDS 7R01NS062849-04 Fate specification of corticospinal neurons by cell autonomous signaling ARLOTTA, PAOLA HARVARD UNIVERSITY MA $123,900
ALS 2011 NINDS 3R01NS072113-02S1 Pathogenic Mechanisms of ALS-Linked TDP Gene Mutation XIA, XUGANG THOMAS JEFFERSON UNIVERSITY PA $26,390
ALS 2011 NIA 1ZIAAG000933-04 Genetic etiology of Amyotrophic Lateral Sclerosis TRAYNOR, BRYAN NIH $460,861
ALS 2011 NIA 1ZIAAG000934-03 Genetic etiology of Fronto-Temporal Dementia TRAYNOR, BRYAN NIH $209,482
ALS 2011 NIA 1ZIAAG000943-04 Function and Pathogenic Mechanism of VAPB in ALS and Other Motor Neuron Diseases CAI, HUAIBIN NIH $289,086
ALS 2011 NIA 1ZIAAG000951-10 Genetic Analysis Of Non-alzheimer Dementias SINGLETON, ANDREW NIH $406,396
ALS 2011 NIEHS 1ZIAES049005-20 Lead And Other Neurotoxins As Risk Factors For Amyotrophic Lateral Sclerosis SANDLER, DALE NIH $48,857
ALS 2011 NINDS 1ZIANS002976-13 Spasticity and spinal mechanisms of human motor control FLOETER, MARY KAY NIH $675,995
ALS 2011 NHLBI 1ZIAHL000202-40 Biochemical Mechanisms of Enzyme Action and Cellular Regulation CHOCK, P. NIH $738,300
ALS 2011 NICHD 1ZIAHD008892-03 Mechanisms of Motor Neuron Disease KALER, STEPHEN NIH $160,143
ALS 2011 NCRR 5M01RR000188-47 6719 CLINICAL TRIAL: PHASE I/II TRIAL USING CYCLOPHOSPHAMIDE AND LOW-DOSE IL-2 TO IN APPEL, STANLEY BAYLOR COLLEGE OF MEDICINE TX $31,265
ALS 2011 NCRR 5P41RR008630-16 5433 STRUCTURAL CHANGES IN HUMAN SOD1 BY POST-TRANLATIONAL MODIFICATION BILSEL, OSMAN ILLINOIS INSTITUTE OF TECHNOLOGY IL $17,741
ALS 2011 NCRR 5P41RR008630-16 5465 METALLATION LEVELS OF PROTEIN AGGREGATES FORMED IN AMYOTROPHIC LATERAL SCLEROSIS MILLER, LISA ILLINOIS INSTITUTE OF TECHNOLOGY IL $59,254
ALS 2011 NCRR 5P41RR015301-09 5851 MOUSE SOD1 AND HUMAN/MOUSE SOD1 CHIMERAS HART, PETER CORNELL UNIVERSITY ITHACA NY $10,975
ALS 2011 NCRR 5P41RR001209-32 6364 SYNCHROTRON X-RAY STUDIES OF BIOMOLECULAR MATERIALS SAFINYA, CYRUS STANFORD UNIVERSITY CA $22,480
ALS 2011 NCRR 5P41RR013642-14 7528 FRONTOTEMPORAL DEMENTIA GENES, IMAGES, & EMOTIONS MILLER, BRUCE UNIVERSITY OF CALIFORNIA LOS ANGELES CA $3,439
ALS 2011 NIMH 5P41RR013642-14 7528 FRONTOTEMPORAL DEMENTIA GENES, IMAGES, & EMOTIONS MILLER, BRUCE UNIVERSITY OF CALIFORNIA LOS ANGELES CA $1,629
ALS 2011 NCRR 2P41RR011823-16 5423 MUTANT SOD1 ASSOCIATION WITH MITOCHONDRIA CLEVELAND, DON UNIVERSITY OF WASHINGTON WA $7,411


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