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RCDC

Project Listing by Category


Back to Estimates of Funding for Various Research, Condition, and Disease Categories (RCDC) Click the column headings to sort project listings.
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CategoryFYFunding ICProject NumberSub Project #Project TitlePI NameOrg NameState / CountryAmount
Orphan Drug 2010 NHLBI 7F32HL090359-02 Genomic Studies in a Rodent Model of Pulmonary Hypertension: A Consomics Approach DESAI, ANKIT UNIVERSITY OF ILLINOIS AT CHICAGO IL $59,918
Orphan Drug 2010 NHLBI 5U01HL072734-06 Coral: Central GFR and Biochemistry Laboratory STEFFES, MICHAEL UNIVERSITY OF MINNESOTA TWIN CITIES MN $244,198
Orphan Drug 2010 NCI 9R01CA139444-06 Integrin-targeted siRNA delivery for therapeutic gene silencing in blood cancers SHIMAOKA, MOTOMU IMMUNE DISEASE INSTITUTE, INC. MA $452,691
Orphan Drug 2010 NINDS 5U44NS059084-03 Intrathecal Cyclosporin for the Treatment of Amyotrophic Lateral Sclerosis (ALS) KARLSSON, JENNY MAAS BIOLAB, INC. NM $890,731
Orphan Drug 2010 NINDS 5R01NS063022-03 sc-rAAV8 via Lumbar Puncture as Spinal Analgesic Drug Delivery Systems BEUTLER, ANDREAS MAYO CLINIC MN $437,372
Orphan Drug 2010 NINDS 1R21NS066129-01 Novel Hsp90 Inhibitors: Proof-of-Principle for Treatment of Motor Neuron Diseases CHEN, RUIHONG NEXGENIX PHARMACEUTICALS HOLDINGS, INC. NY $177,720
Orphan Drug 2010 NIGMS 2R01GM072611-05 Statistical Methods for Ultrahigh-dimensional Biomedical Data FAN, JIANQING PRINCETON UNIVERSITY NJ $266,820
Orphan Drug 2010 NHLBI 5R01HL087836-03 In vivo function and tolerance to Factor VIII variants LEE, BRENDAN BAYLOR COLLEGE OF MEDICINE TX $383,750
Orphan Drug 2010 NCI 5R01CA076287-12 Pretargeted Radioimmunotherapy of CD20+ Lymphomas PRESS, OLIVER FRED HUTCHINSON CANCER RESEARCH CENTER WA $364,467
Orphan Drug 2010 NIAID 5R01AI073342-04 Molecular Detection of Blood Stream Infections in Women with Gynecologic Cancer JORDAN, JEANNE GEORGE WASHINGTON UNIVERSITY DC $308,880
Orphan Drug 2010 NIGMS 4R37GM052382-14 Structure and Mechanism of Protein Prenyltransferases BEESE, LORENA DUKE UNIVERSITY NC $374,400
Orphan Drug 2010 NCI 5R01CA124648-04 An integrative approach to cancer gene discovery in hepatocellular carcinoma POWERS, SCOTT COLD SPRING HARBOR LABORATORY NY $435,804
Orphan Drug 2010 NIAID 5K23AI067567-05 Rebuilding immunity AQUI, NICOLE UNIVERSITY OF PENNSYLVANIA PA $133,029
Orphan Drug 2010 NCI 5R01CA085935-10 Tubulin Mutations and Paclitaxel Resistance CABRAL, FERNANDO UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON TX $263,242
Orphan Drug 2010 NCI 5R01CA131983-03 High Throughput Microscopy Assays to Identify Inhibitors of Metastasis COURTNEIDGE, SARA SANFORD-BURNHAM MEDICAL RESEARCH INSTIT CA $396,325
Orphan Drug 2010 NIGMS 5R01GM054051-13 Substrate Activity Screening: A New Approach to Inhibitor Discovery ELLMAN, JONATHAN UNIVERSITY OF CALIFORNIA BERKELEY CA $111,347
Orphan Drug 2010 NCI 5R01CA125541-04 Studies of a Novel Therapeutic Target in Non-Small Cell Lung Cancer (NSCLC) SALGIA, RAVI UNIVERSITY OF CHICAGO IL $262,485
Orphan Drug 2010 NCI 5R01CA070375-14 Total Synthesis and Biosynthesis of Bioactive Substances WILLIAMS, ROBERT COLORADO STATE UNIVERSITY-FORT COLLINS CO $246,768
Orphan Drug 2010 NINDS 5R01NS055315-03 Mechanisms of SOD1 toxicity in ALS ELLIOTT, JEFFREY UNIVERSITY OF TEXAS SW MED CTR/DALLAS TX $306,002
Orphan Drug 2010 NCI 5R21CA128414-02 Engineered Optimal Adjuvant and Antigen Release from Biodegradable Nanoparticles SALEM, ALIASGER UNIVERSITY OF IOWA IA $132,000
Orphan Drug 2010 NCI 5R01CA130817-03 Interplay Between Cancer and Immune Cells on Targeted Therapy LEE, PETER STANFORD UNIVERSITY CA $444,515
Orphan Drug 2010 NHLBI 5R01HL085133-03 Novel Peptide for Dynamic Regulation of Lung Endothelium NOS/cGMP Functions PATEL, JAWAHARLAL UNIVERSITY OF FLORIDA FL $315,000
Orphan Drug 2010 NIAID 7R01AI043197-13 Alternative approaches for NALT-based immunity to respiratory pathogens BOYAKA, PROSPER OHIO STATE UNIVERSITY OH $371,250
Orphan Drug 2010 NCI 5R01CA050947-18 Molecular Sequelae of Myeloma-Bone Marrow Interactions: Therapeutic Applications ANDERSON, KENNETH DANA-FARBER CANCER INSTITUTE MA $287,403
Orphan Drug 2010 NCI 7R01CA089341-07 Functional Characterization of MLL Gene Fusions CALIGIURI, MICHAEL OHIO STATE UNIVERSITY OH $286,652
Orphan Drug 2010 NCI 5R01CA121327-04 Molecular Basis Of Renal Cell Carcinoma Response to SU11428 MOTZER, ROBERT SLOAN-KETTERING INSTITUTE FOR CANCER RES NY $346,940
Orphan Drug 2010 NIAID 5R01AI071223-03 Experimental Molecular Vaccines for Schistosomiasis SIDDIQUI, AFZAL TEXAS TECH UNIVERSITY HEALTH SCIS CENTER TX $329,271
Orphan Drug 2010 NCI 5F31CA132543-03 Analysis of the Novel Kinase ROR2: A New Molecular Target in Renal Cell Carcinoma WRIGHT, TRICIA UNIVERSITY OF NORTH CAROLINA CHAPEL HILL NC $28,008
Orphan Drug 2010 NIAID 5U01AI069421-04 GHESKIO HIV Clinical Trial Unit PAPE, JEAN GHESKIO CENTER HAITI $2,084,335
Orphan Drug 2010 NIDCD 5R01DC008651-04 A preclinical trial of intratympanic antivirals for CMV-related hearing loss CHOO, DANIEL CHILDREN'S HOSPITAL MED CTR (CINCINNATI) OH $311,119
Orphan Drug 2010 NCI 5R01CA076183-08 Targeting diffuse liver metastases with Herpes virus TANABE, KENNETH MASSACHUSETTS GENERAL HOSPITAL MA $388,804
Orphan Drug 2010 NIAMS 5R03AR056838-02 Mechanisms of BMP Receptor Kinase Dysregulation in Skeletal Dysplasias GROPPE, JAY TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR TX $72,518
Orphan Drug 2010 NCI 5R01CA114021-05 Antitumor Antimitotics That Reverse Tumor Resistance GANGJEE, ALEEM DUQUESNE UNIVERSITY PA $247,872
Orphan Drug 2010 NEI 5R01EY018656-03 Compacted DNA Nanoparticles for Ocular Therapy NAASH, MUNA UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR OK $362,588
Orphan Drug 2010 NCI 7R01CA127935-02 Boronated nucleosides for neutron capture therapy of brain tumors TJARKS, WERNER OHIO STATE UNIVERSITY OH $269,958
Orphan Drug 2010 NCI 5F31CA132613-03 Targeting Oncolytic HSV to Neuroblastoma & Malig. Peripheral Nerve Sheath Tumors MALDONADO, ARTURO CHILDREN'S HOSPITAL MED CTR (CINCINNATI) OH $33,913
Orphan Drug 2010 NCI 5R01CA119904-03 Small Molecule Inhibitors of Oncogenic Human Papillomavirus ANDROPHY, ELLIOT UNIV OF MASSACHUSETTS MED SCH WORCESTER MA $339,782
Orphan Drug 2010 NCI 5R21CA135664-02 Role of microRNAs in genetic mouse models of pancreatic cancer KORC, MURRAY DARTMOUTH COLLEGE NH $139,113
Orphan Drug 2010 NCI 5R01CA073507-13 In Vivo Model of Epstein-Barr Virus Latency LONGNECKER, RICHARD NORTHWESTERN UNIVERSITY IL $499,500
Orphan Drug 2010 NCI 5R01CA041986-23 The Antitumor Antibiotics CC-1065 and the Duocarmycins BOGER, DALE SCRIPPS RESEARCH INSTITUTE CA $408,808
Orphan Drug 2010 NCI 5R01CA133662-02 Novel Compounds to Inactivate Oncogenic Fusion Proteins TORETSKY, JEFFREY GEORGETOWN UNIVERSITY DC $318,513
Orphan Drug 2010 NCI 5R01CA136526-02 Hedgehog and EGF interaction: a novel therapeutic approach for pancreatic cancer FERNANDEZ-ZAPICO, MARTIN MAYO CLINIC MN $253,961
Orphan Drug 2010 NINDS 5R01NS041669-09 Nuclear toxicity of Huntington disease protein LI, XIAO-JIANG EMORY UNIVERSITY GA $330,924
Orphan Drug 2010 NCI 5R01CA127494-02 Proteasome Inhibition and ER Stress MCCONKEY, DAVID UNIVERSITY OF TEXAS MD ANDERSON CAN CTR TX $255,640
Orphan Drug 2010 NCI 5R01CA082830-09 Enhancing Activity of Alkylating Agents in Neuroblastoma REYNOLDS, CHARLES TEXAS TECH UNIVERSITY HEALTH SCIS CENTER TX $1
Orphan Drug 2010 NIDDK 5R01DK066448-07 RETROVIRAL VECTOR-MEDIATED LIVER GENE THERAPY FOR MPS I PONDER, KATHERINE WASHINGTON UNIVERSITY MO $365,072
Orphan Drug 2010 NCI 7R01CA129609-02 Chemoprevention of Head & Neck Cancer Using Controlled Release Polymers MALLERY, SUSAN OHIO STATE UNIVERSITY OH $313,491
Orphan Drug 2010 NIGMS 5R37GM040198-26 FORMATION,INTERACTION & FUNCTION OF SPINDLE COMPONENTS RIEDER, CONLY WADSWORTH CENTER NY $447,804
Orphan Drug 2010 NCI 5R01CA131378-03 Novel Sulindac Derivatives for Colon Cancer Chemoprevention PIAZZA, GARY SOUTHERN RESEARCH INSTITUTE AL $1
Orphan Drug 2010 NICHD 5R01HD020521-24 Molecular Cloning of the Fragile X Site WARREN, STEPHEN EMORY UNIVERSITY GA $574,381
Orphan Drug 2010 NCI 5R01CA124952-03 4'-Substituted nucleoside analogs as anticancer drugs SECRIST, JOHN SOUTHERN RESEARCH INSTITUTE AL $455,093
Orphan Drug 2010 NEI 5R01EY015128-06 Retinal Remodeling MARC, ROBERT UNIVERSITY OF UTAH UT $443,204
Orphan Drug 2010 NCI 5R01CA112519-05 Novel Targeted Therapeutics for Cental Nervous System Malignancies ALI-OSMAN, FRANCIS DUKE UNIVERSITY NC $340,769
Orphan Drug 2010 NCI 5R00CA128926-03 Harnessing Functional Genomics to Reveal Cancer Specific Determinants of Mitosis WHITEHURST, ANGELIQUE UNIVERSITY OF NORTH CAROLINA CHAPEL HILL NC $207,151
Orphan Drug 2010 NCI 5R01CA129611-03 Development of JS-K as an anti-leukemic agent SHAMI, PAUL UNIVERSITY OF UTAH UT $312,288
Orphan Drug 2010 NCI 5R01CA133046-03 Novel Mechanisms by which RAD18 and POLZ affect Response to Anticancer Agents CANMAN, CHRISTINE UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $283,860
Orphan Drug 2010 NIDDK 5R01DK076665-03 Extrinsic Neural Control of Gastrointestinal Function in the Disordered Bowel LINDEN, DAVID MAYO CLINIC MN $301,445
Orphan Drug 2010 NIAID 5R01AI059663-05 Monoclonal antibodies to inhibit Aspergillus germination FELDMESSER, MARTA ALBERT EINSTEIN COL OF MED YESHIVA UNIV NY $391,357
Orphan Drug 2010 NHLBI 5R01HL038794-21 Membrane Proteins of Normal and Abnormal Red Cells SPEICHER, DAVID WISTAR INSTITUTE PA $471,198
Orphan Drug 2010 NINDS 5R21NS064191-02 A novel cell-based high-throughput assay for ALS PRZEDBORSKI, SERGE COLUMBIA UNIVERSITY HEALTH SCIENCES NY $174,080
Orphan Drug 2010 NINDS 5R21NS065481-02 P-GLYCOPROTEIN MEDIATED CHEMORESISTANCE IN ALS THERAPY TROTTI, DAVIDE THOMAS JEFFERSON UNIVERSITY PA $167,294
Orphan Drug 2010 NINDS 5R01NS027941-21 A MULTICENTER STUDY OF IDIOPATHIC GENERALIZED EPILEPSY GREENBERG, DAVID COLUMBIA UNIVERSITY HEALTH SCIENCES NY $889,146
Orphan Drug 2010 NCI 5R01CA132091-03 Targeted Nanoparticle DNA Therapy for Ovarian Cancer SAWICKI, JANET LANKENAU INSTITUTE FOR MEDICAL RESEARCH PA $275,202
Orphan Drug 2010 NIGMS 5R01GM008521-47 Carbon-13 Magnetic Resonance - Methods and Theory GRANT, DAVID UNIVERSITY OF UTAH UT $223,493
Orphan Drug 2010 NIAID 5R01AI040696-13 Regulation of HBV Replication by the Immune System GUIDOTTI, LUCA SCRIPPS RESEARCH INSTITUTE CA $469,013
Orphan Drug 2010 NINDS 5R01NS057412-04 Suppression of the Idua-W402X mutation in an MPS I-H mouse BEDWELL, DAVID UNIVERSITY OF ALABAMA AT BIRMINGHAM AL $314,016
Orphan Drug 2010 NINDS 5R01NS055158-05 Small Molecular Therapeutics for Friedreich's Ataxia GOTTESFELD, JOEL SCRIPPS RESEARCH INSTITUTE CA $409,870
Orphan Drug 2010 NIGMS 1SC3GM089634-01 Thermodynamics of Coupled Binding of Zn(II) and DNA to a Zinc Finger Tumor Suppre GIBNEY, BRIAN BROOKLYN COLLEGE NY $85,400
Orphan Drug 2010 NCI 5R01CA042056-27 Antitumor Antibiotics BOGER, DALE SCRIPPS RESEARCH INSTITUTE CA $487,268
Orphan Drug 2010 NIGMS 1SC1GM082340-01A2 The Fulvene Approach to the Syntheses of Antitumor Agents ERDEN, IHSAN SAN FRANCISCO STATE UNIVERSITY CA $268,625
Orphan Drug 2010 NINDS 5R21NS061051-02 High throughput bioluminescence screening for glioma therapeutics TANNOUS, BAKHOS MASSACHUSETTS GENERAL HOSPITAL MA $191,657
Orphan Drug 2010 NHLBI 5R42HL083531-03 Ex Vivo Gene Therapy for Hemophilia A DOERING, CHRISTOPHER EXPRESSION THERAPEUTICS GA $420,475
Orphan Drug 2010 NCI 5R01CA132946-03 Pharmacogenetics of Ara-C Metabolic Pathway LAMBA, JATINDER UNIVERSITY OF MINNESOTA TWIN CITIES MN $286,251
Orphan Drug 2010 NHLBI 5K24HL086796-04 Proteomic-based Approach to Ventilator Associated Pneumonia SCHNAPP, LYNN UNIVERSITY OF WASHINGTON WA $161,503
Orphan Drug 2010 NCI 5R01CA100634-08 Radiovirotherapy for Multiple Myeloma RUSSELL, STEPHEN MAYO CLINIC MN $328,339
Orphan Drug 2010 NIDDK 1R01DK085040-01 High Throughput Screening Assay Development for Pharmacoperones CONN, P MICHAEL OREGON HEALTH AND SCIENCE UNIVERSITY OR $410,000
Orphan Drug 2010 NCI 5R01CA122779-03 Augmenting Antitumor Immunity after Allografting LUZNIK, LEO JOHNS HOPKINS UNIVERSITY MD $290,836
Orphan Drug 2010 NINDS 5R03NS065299-02 The role of Anaplastic Lymphoma Kinase in motor neuron survival LEFCORT, FRANCES MONTANA STATE UNIVERSITY (BOZEMAN) MT $70,538
Orphan Drug 2010 NCI 5R01CA071540-13 Molecular Basis of Action of the Putative Oncogene BCL-6 BARDWELL, VIVIAN UNIVERSITY OF MINNESOTA TWIN CITIES MN $311,085
Orphan Drug 2010 NCI 1R01CA142723-01 Mechanism of Brd4-mediated papillomavirus host interactions YOU, JIANXIN UNIVERSITY OF PENNSYLVANIA PA $331,135
Orphan Drug 2010 NCI 1R01CA142794-01 Characterization and therapeutic targeting of HIF in LKB1 - deficient lung cancer KIM, WILLIAM UNIVERSITY OF NORTH CAROLINA CHAPEL HILL NC $305,763
Orphan Drug 2010 NCI 1R01CA143107-01 Berberine downregulates MDM2 by interaction with DAXX in cancer cells ZHOU, MUXIANG EMORY UNIVERSITY GA $321,625
Orphan Drug 2010 NCI 5R01CA129339-03 Rectifying defects in tumor vasculature to improve chemo- and radiation therapies SENGER, DONALD BETH ISRAEL DEACONESS MEDICAL CENTER MA $352,750
Orphan Drug 2010 NINDS 5R01NS051756-05 Identification of Novel Drugs that Counter Huntington's Disease FRIEDLANDER, ROBERT BRIGHAM AND WOMEN'S HOSPITAL MA $353,596
Orphan Drug 2010 NCI 1R01CA142855-01 IL12 Gene Therapy For Enhancing Therapeutic Efficacy of Bleomycin Against Oral Tu LI, SHULIN UNIVERSITY OF TEXAS MD ANDERSON CAN CTR TX $327,850
Orphan Drug 2010 NCI 5R01CA120893-04 Dendritic Cell-Brain Tumor Stem Cell Fusion Vaccines PLAUTZ, GREGORY CLEVELAND CLINIC LERNER COL/MED-CWRU OH $293,550
Orphan Drug 2010 NCI 5R01CA129132-03 Development of cambinol analogues as antilymphoma agents BEDALOV, ANTONIO FRED HUTCHINSON CANCER RESEARCH CENTER WA $365,200
Orphan Drug 2010 NCI 5R01CA133525-03 Targeted Therapeutics of LGL Leukemia utilizing Ceramide Nanoliposomes LOUGHRAN, THOMAS PENNSYLVANIA STATE UNIV HERSHEY MED CTR PA $313,325
Orphan Drug 2010 NCI 1R01CA143032-01 Molecular Targeting of Diffuse Large B-cell Lymphoma MELNICK, ARI WEILL MEDICAL COLLEGE OF CORNELL UNIV NY $633,103
Orphan Drug 2010 NCI 1R01CA142873-01 The GNAQ pathway as a therapeutic target in uveal melanoma BASTIAN, BORIS UNIVERSITY OF CALIFORNIA SAN FRANCISCO CA $320,588
Orphan Drug 2010 NINDS 5R21NS060940-02 Identification of Drug Targets for NF1 SANCHEZ, YOLANDA DARTMOUTH COLLEGE NH $205,673
Orphan Drug 2010 NIGMS 5R01GM073028-04 Protein Degradation by the 26S Proteasome LAM, YUENYU WEILL MEDICAL COLLEGE OF CORNELL UNIV NY $308,972
Orphan Drug 2010 NCI 5R01CA101700-06 1H NMR STUDIES OF NON-HODGKINS LYMPHOMA GLICKSON, JERRY UNIVERSITY OF PENNSYLVANIA PA $364,626
Orphan Drug 2010 NCI 1R01CA143204-01 The role of glutaminase 2, a novel p53 target gene in metabolism, in liver cancer FENG, ZHAOHUI UNIV OF MED/DENT NJ-R W JOHNSON MED SCH NJ $334,695
Orphan Drug 2010 NINDS 5R21NS062302-02 NRF2/ARE PATHWAY AS A THERAPEUTIC TARGET FOR AMYOTROPHIC LATERAL SCLEROSIS KIAEI, MAHMOUD WEILL MEDICAL COLLEGE OF CORNELL UNIV NY $182,995
Orphan Drug 2010 NIAID 5R01AI052789-08 KSHV-Ori-Lyt-Dependent DNA Replication YUAN, YAN UNIVERSITY OF PENNSYLVANIA PA $389,813
Orphan Drug 2010 NCI 5R01CA087952-09 TRAIL Therapy for Rhabdomyosacrcoma HOUGHTON, JANET CLEVELAND CLINIC LERNER COL/MED-CWRU OH $234,840
Orphan Drug 2010 NHLBI 5R01HL078564-05 Functional analysis of Tgfbm3 locus in vascular development and disease AKHURST, ROSEMARY UNIVERSITY OF CALIFORNIA SAN FRANCISCO CA $567,457
Orphan Drug 2010 NIAID 1R03AI085226-01 Development of real time fluorescence-based assays for elucidating HCV entry dyna UPRICHARD, SUSAN UNIVERSITY OF ILLINOIS AT CHICAGO IL $78,500
Orphan Drug 2010 NIAID 5R01AI048793-10 Immunogenetic Mechanisms of Vaccine Response POLAND, GREGORY MAYO CLINIC MN $384,066
Orphan Drug 2010 NCI 5R01CA138738-02 Adoptive Immunotherapy of Cancer with IL-12 Secreting Tumor-Targeted T cells BRENTJENS, RENIER SLOAN-KETTERING INSTITUTE FOR CANCER RES NY $393,420
Orphan Drug 2010 NIAID 5R01AI031788-19 New Opportunistic Infections in AIDS Microsporidiosis WEISS, LOUIS ALBERT EINSTEIN COL OF MED YESHIVA UNIV NY $394,737
Orphan Drug 2010 NCI 5R01CA086335-09 Therapeutic modulation of angiogenesis in human gliomas VAN MEIR, ERWIN EMORY UNIVERSITY GA $316,022
Orphan Drug 2010 NCI 5R01CA136895-02 Molecular targets in diffuse large B cell lymphoma DAVE, SANDEEP DUKE UNIVERSITY NC $258,960
Orphan Drug 2010 NIAID 5R01AI071163-03 Lentiviral Gene Therapy for Wiskott-Aldrich Syndrome RAWLINGS, DAVID SEATTLE CHILDREN'S HOSPITAL WA $803,587
Orphan Drug 2010 NINDS 1R21NS067115-01 Donor Innate Lymphocyte Infusion Product for Immunotherapy of Glioblastoma Multif LAMB, LAWRENCE UNIVERSITY OF ALABAMA AT BIRMINGHAM AL $183,125
Orphan Drug 2010 NCI 5R01CA131408-02 HIF genes in head and neck cancer radiotherapy LI, CHUAN-YUAN UNIVERSITY OF COLORADO DENVER CO $310,038
Orphan Drug 2010 NCI 5R21CA140003-02 Novel Targeted Therapy in Pancreatic Cancer SALGIA, RAVI UNIVERSITY OF CHICAGO IL $205,920
Orphan Drug 2010 NCI 5R01CA121107-03 Nitric Oxide Chimera Drugs for Colon Cancer Chemoprevention THATCHER, GREGORY UNIVERSITY OF ILLINOIS AT CHICAGO IL $317,732
Orphan Drug 2010 NCI 5U10CA098543-08 Children's Oncology Group Chair's Grant REAMAN, GREGORY NATIONAL CHILDHOOD CANCER FOUNDATION CA $26,966,030
Orphan Drug 2010 NIAID 5F31AI081485-02 Targeting Trypanosoma brucei S-adenosylmethionine decarboxylase in Drug Discovery VELEZ, NAHIR UNIVERSITY OF TEXAS SW MED CTR/DALLAS TX $28,740
Orphan Drug 2010 NINDS 5F31NS060532-03 Synaptic & intrinsic motoneuron excitability in ALS excitotoxicity SCHUSTER, JENNA NORTHWESTERN UNIVERSITY IL $28,303
Orphan Drug 2010 NIAID 5R42AI074157-03 Experimental Pharmacology and Chemical Studies of Nikkomycin Z GALGIANI, JOHN VALLEY FEVER THERAPIES LLC AZ $350,119
Orphan Drug 2010 NCI 5R21CA135130-02 Peritumorally transformable nanoparticles for intraperitoneal chemotherapy of ova YEO, YOON PURDUE UNIVERSITY WEST LAFAYETTE IN $197,922
Orphan Drug 2010 NCI 5R01CA085289-07 DNA Methylation and Ovarian Cancer NEPHEW, KENNETH INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS IN $241,916
Orphan Drug 2010 NCI 5R01CA139059-02 Human engineered enzymes for L-Arg depletion chemotherapy GEORGIOU, GEORGE UNIVERSITY OF TEXAS AUSTIN TX $346,306
Orphan Drug 2010 NINDS 5K01NS055072-04 Identification of Novel Drugs against Huntington's Disease and Cerebral Ischemia WANG, XIN BRIGHAM AND WOMEN'S HOSPITAL MA $177,012
Orphan Drug 2010 NCI 5R21CA112907-02 8-Chloro-Adenosine for Treatment of CLL (IND 68,229) WIERDA, WILLIAM UNIVERSITY OF TEXAS MD ANDERSON CAN CTR TX $305,800
Orphan Drug 2010 NIGMS 5R01GM084473-03 Biosynthesis of Pyrrolo[1,4]benzodiazepines, potent antitumor antibiotics GERRATANA, BARBARA UNIVERSITY OF MARYLAND COLLEGE PK CAMPUS MD $237,018
Orphan Drug 2010 NCI 5R01CA083724-09 Chromosomal Abnormalities in Myeloma as Detected by FISH FONSECA, RAFAEL MAYO CLINIC ARIZONA AZ $338,746
Orphan Drug 2010 NIDCR 5R01DE019126-02 Biomarkers to Guide Treatment and Improve Survival in Oral/Oropharyngeal Cancer CAREY, THOMAS UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $344,149
Orphan Drug 2010 NINDS 5R01NS066582-06 Molecular Studies of Brain Malformations HU, HUAIYU UPSTATE MEDICAL UNIVERSITY NY $204,003
Orphan Drug 2010 NIBIB 5R01EB008733-02 Precision engineering of ultrasonically-targeted drug delivery vehicles DAYTON, PAUL NORTH CAROLINA STATE UNIVERSITY RALEIGH NC $305,946
Orphan Drug 2010 NINDS 5R01NS064261-02 GSK3: immunoregulator in experimental autoimmune encephalomyelitis (EAE) DE SARNO, PATRIZIA UNIVERSITY OF ALABAMA AT BIRMINGHAM AL $285,537
Orphan Drug 2010 NIBIB 5R21EB009265-02 Focusing of Drug-Coated Nano-Particles to Deep Tissue Tumors by Feedback Control SHAPIRO, BENJAMIN UNIVERSITY OF MARYLAND COLLEGE PK CAMPUS MD $145,694
Orphan Drug 2010 NCI 1R01CA124951-01A2 Novel CTD inhibitors with synthetic lethality to oncogenic Ras for cancer therapy FANG, BINGLIANG UNIVERSITY OF TEXAS MD ANDERSON CAN CTR TX $310,586
Orphan Drug 2010 NIA 5P01AG021601-07 Novel Therapeutics for Prion Diseases PRUSINER, STANLEY UNIVERSITY OF CALIFORNIA SAN FRANCISCO CA $1,925,862
Orphan Drug 2010 NCI 5R01CA128864-03 Incorporating FLT3 inhibitors into AML treatment regimens LEVIS, MARK JOHNS HOPKINS UNIVERSITY MD $340,300
Orphan Drug 2010 NCI 1R01CA138535-01A1 Novel Heparanase Inhibitors for Cancer Therapy SANDERSON, RALPH UNIVERSITY OF ALABAMA AT BIRMINGHAM AL $368,525
Orphan Drug 2010 NINDS 1U01NS061799-01A2 FOR-DMD:Double-blind randomized trial to optimize steroid regimen in Duchenne MD GRIGGS, ROBERT UNIVERSITY OF ROCHESTER NY $3,946,196
Orphan Drug 2010 NIAID 5R01AI082577-03 Validation and development of trypanosomal phosphodiesterase inhibitors for treat POLLASTRI, MICHAEL NORTHEASTERN UNIVERSITY MA $536,539
Orphan Drug 2010 NCI 5R01CA101135-07 Molecular Characterization of Cell-Cell Interactions in Cancer Metastasis KONSTANTOPOULOS, KONSTANTINOS JOHNS HOPKINS UNIVERSITY MD $303,588
Orphan Drug 2010 NCI 5R03CA139266-02 Prodrug enzyme therapy of pancreatic cancer mediated by oncolytic HSV vector LANUTI, MICHAEL MASSACHUSETTS GENERAL HOSPITAL MA $88,500
Orphan Drug 2010 NHLBI 5R37HL048129-16 Role and Regulation of Sodium, Potasium ATPase in Lung SZNAJDER, JACOB NORTHWESTERN UNIVERSITY IL $383,303
Orphan Drug 2010 NCI 1R01CA138635-01A1 Multiple Tumor Antigen-loaded DC Vaccine for Hepatocellular Cancer BUTTERFIELD, LISA UNIVERSITY OF PITTSBURGH AT PITTSBURGH PA $267,383
Orphan Drug 2010 NINDS 1R01NS057670-01A1 The regulation of myeloid cell development and mobilization during autoimmune dem SEGAL, BENJAMIN UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $261,498
Orphan Drug 2010 NCI 2R01CA113669-06 Developmental Signaling Pathways in Pancreatic Cancer MAITRA, ANIRBAN JOHNS HOPKINS UNIVERSITY MD $316,328
Orphan Drug 2010 NINDS 1R21NS067482-01 Development of a novel quinazoline compound for the treatment of spinal muscular DIDONATO, CHRISTINE CHILDREN'S MEMORIAL HOSPITAL (CHICAGO) IL $220,500
Orphan Drug 2010 NCI 5R01CA055349-17 Biology of Alpha Particle Immunotherapy SCHEINBERG, DAVID SLOAN-KETTERING INSTITUTE FOR CANCER RES NY $436,088
Orphan Drug 2010 NHLBI 2R01HL078701-05A2 Regulation of Leukocyte Migration by Plasminogen HOOVER-PLOW, JANE CLEVELAND CLINIC LERNER COL/MED-CWRU OH $392,500
Orphan Drug 2010 NIMH 1R01MH085802-01A1 Mechanisms and Therapeutics for Rett Syndrome SUR, MRIGANKA MASSACHUSETTS INSTITUTE OF TECHNOLOGY MA $420,000
Orphan Drug 2010 NCI 2P01CA078378-11A2 7236 Targeting Myeloma Cell-Host Bone Marrow Interactions ANDERSON, KENNETH DANA-FARBER CANCER INSTITUTE MA $1,025,504
Orphan Drug 2010 NCI 2P01CA078378-11A2 7239 Adoptive Immunotherapy for Multiple Myeloma Using Educated T Cells KUFE, DONALD DANA-FARBER CANCER INSTITUTE MA $324,064
Orphan Drug 2010 NCI 2R01CA025000-31A1 CD8+ T Cell-Mediated Immunotherapy of Autochthonous SV40 T Antigen-Induced Tumors SCHELL, TODD PENNSYLVANIA STATE UNIV HERSHEY MED CTR PA $386,069
Orphan Drug 2010 NCI 1R01CA139099-01A1 Molecular Combinatorial Therapy of Glioblastoma Multiforme DEBINSKI, WALDEMAR WAKE FOREST UNIVERSITY HEALTH SCIENCES NC $307,100
Orphan Drug 2010 NIAID 5R01AI068109-05 Prophylactic Vaccines for Schistosomiasis HARN, DONALD UNIVERSITY OF GEORGIA (UGA) GA $402,411
Orphan Drug 2010 NINDS 1U01NS061795-01A2 Biostatistics and Data Management for a Trial of Corticosteroid Regimens in DMD MCDERMOTT, MICHAEL UNIVERSITY OF ROCHESTER NY $902,639
Orphan Drug 2010 NINDS 2U01NS049640-06 Clinical Trial of Ceftriaxone in Subjects with ALS CUDKOWICZ, MERIT MASSACHUSETTS GENERAL HOSPITAL MA $6,809,454
Orphan Drug 2010 NCI 5R01CA109663-06 CD45 Pretargeted Radioimmunotherapy for AML PRESS, OLIVER FRED HUTCHINSON CANCER RESEARCH CENTER WA $303,343
Orphan Drug 2010 NCI 2R01CA077263-10A2 Taxol: Mechanisms of Action and Resistance HORWITZ, SUSAN ALBERT EINSTEIN COL OF MED YESHIVA UNIV NY $415,000
Orphan Drug 2010 NCI 1R01CA138636-01A1 BETR Therapy for Herpesvirus-Associated Tumors POMPER, MARTIN JOHNS HOPKINS UNIVERSITY MD $582,447
Orphan Drug 2010 NCI 2R01CA093455-06 Discovery of Novel Antitumor Agents Effective Against Pancreatic Cancer WRIGHT, AMY FLORIDA ATLANTIC UNIVERSITY FL $337,470
Orphan Drug 2010 NIMH 1R01MH085324-01A2 Synaptic Phenotype, Development, and Plasticity in the Fragile X Mouse COX, CHARLES UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN IL $421,590
Orphan Drug 2010 NCI 1R01CA134951-01A2 Layer-by-layer nanocarriers for highly efficient solubilization of insoluble drug TORCHILIN, VLADIMIR NORTHEASTERN UNIVERSITY MA $326,209
Orphan Drug 2010 NIAID 2R01AI042015-11A2 Regulation of the Poly Sialic Virulence Factor VIMR, ERIC UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN IL $217,938
Orphan Drug 2010 NHLBI 1R01HL095791-01A1 Novel Biologic Therapies for BMT: Mechanistic Evaluation in Rhesus Macaques KEAN, LESLIE EMORY UNIVERSITY GA $834,441
Orphan Drug 2010 NINDS 1U01NS065102-01A1 Development and Testing of Hsp90 Inhibitors PETRUCELLI, LEONARD MAYO CLINIC JACKSONVILLE FL $746,857
Orphan Drug 2010 NCI 1P01CA139980-01A1 7451 Quantitative Analysis of Cell Death Pathways in Cancer SORGER, PETER HARVARD UNIVERSITY (MEDICAL SCHOOL) MA $289,997
Orphan Drug 2010 NCI 1R21CA143785-01 Enhancing antitumor immunity with anti-PD-1 antibody in follicular lymphoma. NEELAPU, SATTVA UNIVERSITY OF TEXAS MD ANDERSON CAN CTR TX $288,425
Orphan Drug 2010 NCI 2R01CA108056-06 Structural Biology of AML (CBFA2) and AML1-ETO BUSHWELLER, JOHN UNIVERSITY OF VIRGINIA CHARLOTTESVILLE VA $380,244
Orphan Drug 2010 NIAID 1K23AI077759-01A1 Post-Vacc. HPV Genotype Distr. Among HIV+ and HIV- Young Women in S. Africa ADLER, DAVID UNIVERSITY OF ROCHESTER NY $125,838
Orphan Drug 2010 NCI 5R21CA129590-03 Selenium as an adjuvant to imatinib therapy DIAMOND, ALAN UNIVERSITY OF ILLINOIS AT CHICAGO IL $211,950
Orphan Drug 2010 NIAID 5R01AI051227-07 Polyomavirus Infection after Kidney Transplantation RANDHAWA, PARMJEET UNIVERSITY OF PITTSBURGH AT PITTSBURGH PA $317,109
Orphan Drug 2010 NIAID 5R01AI063360-05 Immune Response to Polyomavirus Infection RANDHAWA, PARMJEET UNIVERSITY OF PITTSBURGH AT PITTSBURGH PA $396,012
Orphan Drug 2010 NCI 1R21CA139290-01A1 Mitochondrial Dysfunction and Chemoresistance in Malignant Gliomas GRIGUER, CORINNE UNIVERSITY OF ALABAMA AT BIRMINGHAM AL $191,183
Orphan Drug 2010 NCI 1R21CA141404-01A1 Multiple kinase target inhibition with EMND-2076 in multiple myeloma FARAG, SHERIF INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS IN $319,550
Orphan Drug 2010 NCI 1R21CA135594-01A2 NANO-DELIVERY OF MITOCHONDRIA-SPECIFIC CERAMIDE TO OVERCOME TUMOR DRUG RESISTANCE AMIJI, MANSOOR NORTHEASTERN UNIVERSITY MA $169,423
Orphan Drug 2010 NCI 1R01CA139389-01A1 Lymphoma Therapy with Reprogrammed Measles Viruses CATTANEO, ROBERTO MAYO CLINIC MN $313,533
Orphan Drug 2010 NCI 1R21CA141275-01A1 Characterizing Clonogenic Populations in Mantle Cell Lymphoma MCCARTY, NAMI UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON TX $163,125
Orphan Drug 2010 NCI 5R01CA139032-02 AID-mediated genetic instability in BCR-ABL1-transformed B cell lineage leukemia MUSCHEN, MARKUS CHILDREN'S HOSPITAL LOS ANGELES CA $332,000
Orphan Drug 2010 NCI 5R01CA129554-02 Oxygen and photosensitizer levels in photodynamic therapy of head and neck tumors BUSCH, THERESA UNIVERSITY OF PENNSYLVANIA PA $347,602
Orphan Drug 2010 NIDCD 5R01DC009246-02 Deciphering the Usher I protein interactome using a genetic approach ZHENG, QING CASE WESTERN RESERVE UNIVERSITY OH $330,289
Orphan Drug 2010 NCI 7R01CA102031-06 Phamacological modulation of epigenetic changes in AML MARCUCCI, GUIDO OHIO STATE UNIVERSITY OH $300,000
Orphan Drug 2010 NCI 1R21CA139385-01A1 Tumor-specific agents for cancer imaging VICENTE, MARIA DA GRACA LOUISIANA STATE UNIV A&M COL BATON ROUGE LA $193,140
Orphan Drug 2010 NCI 1R21CA141348-01A1 Dynamic multimodal imaging of tumor hypoxia and vascular profiles in glioblastoma ZHAO, DAWEN UNIVERSITY OF TEXAS SW MED CTR/DALLAS TX $172,369
Orphan Drug 2010 NCI 2R01CA102707-06A1 Inhibition of Cytochrome c-induced Caspase Activation KORNBLUTH, SALLY DUKE UNIVERSITY NC $271,190
Orphan Drug 2010 NCI 1R21CA150277-01A1 Effects of Danshen constituent Tanshinone IIA on tumor vasculature CHEN, BIN UNIVERSITY OF THE SCIENCES PHILADELPHIA PA $154,969
Orphan Drug 2010 NIGMS 5F32GM083438-03 Structural Analysis of DNA Replication Machinery of P. falciparum LINDNER, SCOTT SEATTLE BIOMEDICAL RESEARCH INSTITUTE WA $52,154
Orphan Drug 2010 NHLBI 5R01HL092179-02 Hematopoietic gene therapy for hemophilia A DOERING, CHRISTOPHER EMORY UNIVERSITY GA $387,500
Orphan Drug 2010 NIAID 5R01AI076535-03 Combination therapies for chronic HBV, liver disease and cancer FEITELSON, MARK TEMPLE UNIVERSITY PA $350,559
Orphan Drug 2010 NIAID 1K22AI081901-01A1 Towards a Structural Systems Biology Approach for Anti-Trypanosomal Therapeutics AMARO, ROMMIE UNIVERSITY OF CALIFORNIA IRVINE CA $162,000
Orphan Drug 2010 NCI 1R01CA134604-01A2 Investigating Oncogenic Cooperation between BMI-1 and EWS-FLI1 LAWLOR, ELIZABETH UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $320,588
Orphan Drug 2010 NCI 1R21CA132277-01A2 Adoptive T-Cell Therapy for Acute Leukemia BALL, EDWARD UNIVERSITY OF CALIFORNIA SAN DIEGO CA $320,588
Orphan Drug 2010 NIAID 5R01AI072204-04 Cervical, Anal, and Oral HPV Persistence and Risk Factors Among Adolescent Girls DIAZ, ANGELA MOUNT SINAI SCHOOL OF MEDICINE NY $807,540
Orphan Drug 2010 NCI 5R37CA011898-40 Brain Tumors - Immunological and Biological Studies BIGNER, DARELL DUKE UNIVERSITY NC $703,967
Orphan Drug 2010 NCI 2R01CA115884-06 HTLV-I Tax activates the anaphase promoting complex GIAM, CHOU-ZEN HENRY M. JACKSON FDN FOR THE ADV MIL/MED MD $286,847
Orphan Drug 2010 NCI 5U01CA069852-16 Phase I Clinical Trials of Anti-Cancer Agents RATAIN, MARK UNIVERSITY OF CHICAGO IL $804,916
Orphan Drug 2010 NCI 5R01CA051578-18 A POLYMERIC DRUG DELIVERY SYSTEM FOR CANCER THERAPY KOPECEK, JINDRICH UNIVERSITY OF UTAH UT $236,153
Orphan Drug 2010 NCI 5R01CA141341-10 Rac GTPase-Specific Small Molecular Inhibitors ZHENG, YI CHILDREN'S HOSPITAL MED CTR (CINCINNATI) OH $255,099
Orphan Drug 2010 NCI 5R01CA135109-03 Carbon Nanotubes as Multi-functional Spectroscopic Markers and Delivery Agents fo DAI, HONGJIE STANFORD UNIVERSITY CA $328,936
Orphan Drug 2010 NINDS 1R01NS066278-01A1 Role of MELK in glioblastomas TERSKIKH, ALEXEY SANFORD-BURNHAM MEDICAL RESEARCH INSTIT CA $430,850
Orphan Drug 2010 NIA 5R01AG019206-09 Synaptic toxicity of Huntington disease protein LI, XIAO-JIANG EMORY UNIVERSITY GA $304,303
Orphan Drug 2010 NIAID 5R01AI076183-08 Structural and Functional Studies of gp42 and HLA Class II in EBV Entry LONGNECKER, RICHARD NORTHWESTERN UNIVERSITY IL $411,741
Orphan Drug 2010 NINDS 2R01NS037766-11 Cytokines in Glial Cells and EAE Brain SINGH, INDERJIT MEDICAL UNIVERSITY OF SOUTH CAROLINA SC $322,656
Orphan Drug 2010 NCI 1R01CA133697-01A1 Nanovalve Platform: Targeted, Controlled, Release of Anticancer Drugs TAMANOI, FUYUHIKO UNIVERSITY OF CALIFORNIA LOS ANGELES CA $420,659
Orphan Drug 2010 NIA 5R01AG029601-04 Nanoscale Electrostatic Assemblies for Multi-Agent Drug Delivery from HAMMOND, PAULA MASSACHUSETTS INSTITUTE OF TECHNOLOGY MA $417,965
Orphan Drug 2010 NIAID 5R01AI054384-20 Biochemistry of Protein Prenylation GELB, MICHAEL UNIVERSITY OF WASHINGTON WA $619,554
Orphan Drug 2010 NCI 1R43CA144086-01 Monoclonal Antibody to FGF2 for Treatment of Hepatocellular Carcinoma and Other C KIM, K JIN GALAXY BIOTECH, LLC CA $117,637
Orphan Drug 2010 NCI 5R01CA057683-17 Toward a molecular classification of human gliomas LOUIS, DAVID MASSACHUSETTS GENERAL HOSPITAL MA $311,154
Orphan Drug 2010 NIAID 5U01AI078060-03 A Tetravalent Dengue Vaccine Based on Alphavirus Replicons WHITE, LAURA UNIVERSITY OF NORTH CAROLINA CHAPEL HILL NC $933,677
Orphan Drug 2010 NINDS 5K23NS055733-04 Cognition in Clinical Trials for Huntington's Disease BEGLINGER, LEIGH UNIVERSITY OF IOWA IA $161,599
Orphan Drug 2010 NICHD 1U10HD063106-01 Collaborative Pediatric Research Critical Care Network(U10) SHANLEY, THOMAS UNIVERSITY OF MICHIGAN AT ANN ARBOR MI $258,211
Orphan Drug 2010 NIAID 1R43AI081332-01A1 TARGETING THE B-CELL RECPTOR COMPLEX AND DOWNSTREATM KINASES WELT, SYDNEY WELT BIO-MOLECULAR PHARMACEUTICAL, LLC NY $127,330
Orphan Drug 2010 NIAID 1R01AI085596-01 Mechanism of action and therapeutic targeting of properdin in complement injury SONG, WENCHAO UNIVERSITY OF PENNSYLVANIA PA $392,205
Orphan Drug 2010 NCI 5R01CA036725-25 Immunotoxins in bone marrow transplantation VALLERA, DANIEL UNIVERSITY OF MINNESOTA TWIN CITIES MN $236,154
Orphan Drug 2010 NCI 5R01CA102792-08 Use of Beta-lapachone for Lung Cancer Chemotherapy BOOTHMAN, DAVID UNIVERSITY OF TEXAS SW MED CTR/DALLAS TX $341,159
Orphan Drug 2010 NCI 5R01CA134773-02 Multi-Modal Lysosomotropic Death Therapy for Malignant Peripheral Nerve Sheath Tu ROTH, KEVIN UNIVERSITY OF ALABAMA AT BIRMINGHAM AL $243,190
Orphan Drug 2010 NIAID 5R01AI041769-13 Cellular Mechanisms of PTLD in Transplant Recipients MARTINEZ, OLIVIA STANFORD UNIVERSITY CA $411,227
Orphan Drug 2010 NIA 5R01AG026661-05 Role of RecQ Helicases to Prevent Senescence By c-Myc GRANDORI, CARLA FRED HUTCHINSON CANCER RESEARCH CENTER WA $300,693
Orphan Drug 2010 NCI 5R01CA120552-05 Prevention of Metastatic Cancer Using a Novel Vitamin E Analog AKPORIAYE, EMMANUEL PROVIDENCE PORTLAND MEDICAL CENTER OR $248,463
Orphan Drug 2010 NIAID 5R01AI072453-04 Directed evolution of inhibitors of anthrax toxin FORSTER, ANTHONY VANDERBILT UNIVERSITY TN $298,155
Orphan Drug 2010 NCI 1R43CA141742-01A1 Targeted Radiotherapy of Ovarian Cancer with a Novel, High Payload Radioligand SANDS, HOWARD SOLIXIA, INC. PA $161,098
Orphan Drug 2010 NINDS 5R01NS056422-04 Role of Fas death receptor signaling in motor neuron degeneration HENDERSON, CHRISTOPHER COLUMBIA UNIVERSITY HEALTH SCIENCES NY $348,666
Orphan Drug 2010 NINDS 5U01NS050094-05 Characterizing Beta Lactams as Neuroprotectants for Amyotrophic Lateral Sclerosis ROTHSTEIN, JEFFREY JOHNS HOPKINS UNIVERSITY MD $1
Orphan Drug 2010 NCI 1R42CA144104-01 Sideport Needle Array Technologies for Prioritizing Drugs for Cancer Patients OLSON, JAMES PRESAGE BIOSCIENCES, INC. CA $164,492
Orphan Drug 2010 NHLBI 1R43HL096155-01A1 USP34 as a novel target for treatment of idiopathic pulmonary fibrosis GOLDENBERG, SETH PROGENRA, INC. PA $265,823
Orphan Drug 2010 NIDDK 1R43DK085754-01 Outpatient treatment for portal hypertension BOLOTIN, ELIJAH PHARMAIN CORPORATION WA $223,422
Orphan Drug 2010 NEI 1R43EY019811-01A1 Vision restoration with photoswitch technology BLATZ, ANDREW PHOTOSWITCH BIOSCIENCES, INC. CA $374,532
Orphan Drug 2010 NHLBI 2R44HL091601-02 Novel Therapeutic Approach to Acute Lung Injury NAVANKASATTUSAS, SUTIP NAVIGEN, INC. UT $554,199
Orphan Drug 2010 NHLBI 1R43HL097529-01A1 A novel JAK inhibitor for the treatment of pulmonary arterial hypertension ZISMAN, LAWRENCE PULMOKINE, INC. NY $311,629
Orphan Drug 2010 NCI 5R01CA125360-03 Self-Assemblying Immunotherapeutic Nanorings WAGNER, CARSTON UNIVERSITY OF MINNESOTA TWIN CITIES MN $302,786
Orphan Drug 2010 NCI 5R01CA120383-04 Transposon Mediated Gene Therapy for Colorectal Cancer MCIVOR, R UNIVERSITY OF MINNESOTA TWIN CITIES MN $301,442
Orphan Drug 2010 NCI 5R37CA055254-20 BIOSYNTHESIS of Taxol CROTEAU, RODNEY WASHINGTON STATE UNIVERSITY WA $320,721
Orphan Drug 2010 NIDDK 1R43DK085910-01 New Rat Model For Autoimmune Therapy Safety/Efficacy WHALEN, BARBARA BIOMEDICAL RESEARCH MODELS, INC. MA $293,447
Orphan Drug 2010 NCI 5R01CA101850-06 ENGINEERED INTELLIGENT MICELLE FOR TUMOR pH TARGETING BAE, YOU UNIVERSITY OF UTAH UT $271,181
Orphan Drug 2010 NIEHS 1R44ES018017-01 Validation of a Rodent Mutagenicity Assay DERTINGER, STEPHEN LITRON LABORATORIES, LTD. NY $348,293
Orphan Drug 2010 NIAID 5U01AI077822-03 Novel Therapeutics for Class B Protozoa REED, SHARON UNIVERSITY OF CALIFORNIA SAN DIEGO CA $1,380,550
Orphan Drug 2010 NCI 5R01CA136699-02 A Novel Screen for Compounds that Outflank BCR-ABL Drug-Resistance COLICELLI, JOHN UNIVERSITY OF CALIFORNIA LOS ANGELES CA $315,371
Orphan Drug 2010 NHLBI 1R43HL099249-01 Novel Hematopoietic Conditioning Agents for Treatment of Hematological Diseases BURKHART, CATHERINE TARTIS, INC. NY $112,885
Orphan Drug 2010 NCI 1R43CA144591-01 EGFR-Targeted Nanoemulsions for Imaging and Therapy of Ovarian Cancer COLEMAN, TIMOTHY NEMUCORE MEDICAL INNOVATIONS, INC. MA $149,855
Orphan Drug 2010 NCI 5R01CA124898-04 H/D Exchange Coupled to MS to Study Drug-Induced Change in Microtuble Structure HORWITZ, SUSAN ALBERT EINSTEIN COL OF MED YESHIVA UNIV NY $315,400
Orphan Drug 2010 NCI 5K23CA124465-03 Novel Biologic Therapies for Hodgkin's Lymphoma KASAMON, YVETTE JOHNS HOPKINS UNIVERSITY MD $140,940
Orphan Drug 2010 NCI 5R01CA098468-07 Improving CPT-11 Efficacy Using Structural and Chemical Biology REDINBO, MATTHEW UNIVERSITY OF NORTH CAROLINA CHAPEL HILL NC $262,200
Orphan Drug 2010 NIAID 1R43AI084350-01A1 Development of Multivalent Vaccines Against Yellow Fever and Arena Viruses FLICK, RAMON BIOPROTECTION SYSTEMS CORPORATION IA $299,975
Orphan Drug 2010 NCI 1F32CA142091-01A1 Clinical pharmacology of cyclophosphamide in pediatric medulloblastoma patients TAGEN, MICHAEL ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $47,606
Orphan Drug 2010 NIAID 1R41AI085944-01 Nanoemulsion-based vaccine for chronic hepatitis B virus BAKER, JAMES NANOBIO CORPORATION MI $297,250
Orphan Drug 2010 NCI 5R01CA138762-02 Splicing factors as therapeutic targets for the treatment of ovarian cancer BECK, WILLIAM UNIVERSITY OF ILLINOIS AT CHICAGO IL $313,715
Orphan Drug 2010 NINDS 5R01NS041922-07 Longitudinal Neuroimaging in Sturge-Weber Syndrome JUHASZ, CSABA WAYNE STATE UNIVERSITY MI $295,606
Orphan Drug 2010 NCI 5K23CA123149-04 Antigen Discovery and Development of Tumor-Specific Lymphoma Immunotherapy NEELAPU, SATTVA UNIVERSITY OF TEXAS MD ANDERSON CAN CTR TX $136,080
Orphan Drug 2010 NCI 7R01CA075115-13 RAl GTPases and partners in human bladder cancer metastasis THEODORESCU, DAN UNIVERSITY OF COLORADO DENVER CO $351,338
Orphan Drug 2010 NCI 5R37CA044848-24 Antitumor-Antibiotics from Marine Microorganisms FENICAL, WILLIAM UNIVERSITY OF CALIFORNIA SAN DIEGO CA $384,546
Orphan Drug 2010 NIAID 5R01AI065622-05 Redox Balance & Drug Development in Schistosoma mansoni WILLIAMS, DAVID RUSH UNIVERSITY MEDICAL CENTER IL $263,031
Orphan Drug 2010 NCI 7U10CA031946-29 Cancer and Leukemia Group B BERTAGNOLLI, MONICA BRIGHAM AND WOMEN'S HOSPITAL MA $11,034,745
Orphan Drug 2010 NCI 1R43CA144817-01 Development of Novel Sensitizer to Improve Response of Hypoxic Tumors to Radiatio UNGER, EVAN NUVOX PHARMA, LLC AZ $204,360
Orphan Drug 2010 NINDS 1R21NS068057-01 Neuroimmunology of Vaccines in Adoptive T-cell Therapy for Brain Tumor SAMPSON, JOHN DUKE UNIVERSITY NC $235,500
Orphan Drug 2010 NCI 5U01CA081457-12 Pediatric Brain Tumor Consortium (PBTC) BOYETT, JAMES ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $1,445,838
Orphan Drug 2010 NINDS 5U01CA081457-12 Pediatric Brain Tumor Consortium (PBTC) BOYETT, JAMES ST. JUDE CHILDREN'S RESEARCH HOSPITAL TN $792,240
Orphan Drug 2010 NCI 5R01CA124414-04 BETA-CATENIN AS A THERAPEUTIC TARGET IN HEPATOCELLULAR CANCER MONGA, SATDARSHAN UNIVERSITY OF PITTSBURGH AT PITTSBURGH PA $249,404
Orphan Drug 2010 NCI 5R01CA100830-08 Oncolytic VSV for Hepatocellular Carcinoma WOO, SAVIO MOUNT SINAI SCHOOL OF MEDICINE NY $338,076
Orphan Drug 2010 NCI 5R01CA112446-05 DNA Lesion Bypass Polymerases and Therapeutic Compounds CHOU, KAI-MING INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS IN $1
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