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Skip Navigation LinksHome > Funding > NIH Categorical Spending

RCDC

Estimates of Funding for Various Research, Condition, and Disease Categories (RCDC)


Table Published: February 24, 2020

The table below displays the annual support level for various research, condition, and disease categories based on grants, contracts, and other funding mechanisms used across the National Institutes of Health (NIH), as well as disease burden data published by the National Center for Health Statistics (NCHS) at the Centers for Disease Control & Prevention (CDC).

At the request of Congress, the NIH embarked on a process to provide better consistency and transparency in the reporting of its funded research. This new process, implemented in 2008 through the Research, Condition, and Disease Categorization (RCDC) system, uses sophisticated text data mining (categorizing and clustering using words and multiword phrases) in conjunction with NIH-wide definitions used to match projects to categories. RCDC use of data mining improves consistency and eliminates the wide variability in defining the research categories reported. The definitions are a list of terms and concepts selected by NIH scientific experts to define a research category. The research category levels represent the NIH's best estimates based on the category definitions.

In 2016, the NIH added mortality and prevalence data from two sources of consistent and nationally-representative disease statistics provided by NCHS/CDC. These data are reported alongside the budgeting categories to provide the public and policymakers with information that is helpful for understanding the NIH research portfolio and its relationship to public health needs. However, NIH believes that the best way to understand disease burdens is by examining patterns in the larger context of multiple methods and measurements, chosen on a case-by-case basis as appropriate for each disease or condition. Further descriptions of these disease statistics can be found here.

The NIH does not expressly budget by category. The annual estimates reflect amounts that change as a result of science, actual research projects funded, and the NIH budget. The research categories are not mutually exclusive. Individual research projects can be included in multiple categories so amounts depicted within each column of this table do not add up to 100 percent of NIH-funded research.


The table shows historical data for FY 2016 through FY 2019. Estimates for FY 2020 and FY2021 are based on RCDC actual data.

Total Number of Research/Disease Areas: 292

Click here for instructions on how to use the data table below.

New: Click here to view or download a summary table in Excel file format of historical annual funding levels for categories from FY 2008 through FY 2015.

Search Research/ Disease Areas
SEARCH RESEARCH/ DISEASE AREAS                             Print   Help
Research/Disease Areas
(Dollars in millions and rounded)		FY 2016 ActualFY 2017 ActualFY 2018 ActualFY 2019 ActualFY 2020 EstimatedFY 2021 Estimated2017
US Mortality
19/		2017
US Prevalence (Standard Error) 19/
Acquired Cognitive Impairment $1,132 $1,560 $1,978 $2,423 $2,505 $2,315 - -
Acute Respiratory Distress Syndrome $103 $107 $123 $126 $132 $121 10,584 -
Adolescent Sexual Activity $91 $99 $96 $102 $106 $98 - -
Agent Orange & Dioxin $9 $11 $10 $8 $8 $8 - -
Aging $3,150 $3,572 $4,084 $4,653 $5,195 $4,724 - -
Alcoholism, Alcohol Use and Health 1/ $486 $500 $534 $556 $577 $528 72,371 -
Allergic Rhinitis (Hay Fever) $7 $6 $5 $7 $7 $7 81 8.1% (0.22%)
ALS $52 $78 $83 $105 $111 $102 - -
Alzheimer's Disease $929 $1,361 $1,789 $2,240 $2,644 $2,406 146,894 -
Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD) 2/ $986 $1,423 $1,911 $2,398 $2,818 $2,564 - -
Alzheimer's Disease Related Dementias (ADRD) 2/ $175 $249 $387 $515 $595 $549 - -
American Indian or Alaska Native 22/ $180 $181 $175 $214 $226 $207 - -
Anorexia $8 $10 $11 $11 $12 $11 126 -
Anthrax $51 $50 $43 $29 $31 $28 - -
Antimicrobial Resistance $420 $470 $522 $577 $631 $583 - -
Anxiety Disorders $174 $190 $213 $233 $240 $220 - -
Aphasia $30 $34 $33 $43 $45 $41 2,163 -
Arctic $24 $20 $24 $27 $28 $25 - -
Arthritis $248 $240 $246 $268 $275 $251 - 23.8% (0.32%)
Assistive Technology $296 $299 $345 $385 $390 $357 - -
Asthma $266 $286 $304 $313 $335 $308 10,302 7.7% (0.20%)
Ataxia Telangiectasia $7 $10 $10 $8 $9 $8 17 -
Atherosclerosis $385 $426 $417 $400 $417 $380 29,893 -
Attention Deficit Disorder (ADD) $47 $54 $58 $64 $70 $70 85 9.4% (0.40%)**
Autism $232 $245 $281 $290 $314 $287 290 2.3% (0.20%)**
Autoimmune Disease $883 $934 $888 $988 $1,055 $968 - -
Back Pain $23 $30 $30 $170 $125 $122 - -
Basic Behavioral and Social Science $1,804 $1,993 $2,252 $2,561 $2,712 $2,483 - -
Batten Disease $5 $5 $7 $6 $6 $6 - -
Behavioral and Social Science $4,137 $4,547 $5,096 $6,499 $6,698 $6,157 - -
Biodefense 3/ $1,951 $1,964 $2,170 $2,353 $2,522 $2,337 - -
Bioengineering $3,841 $4,106 $4,592 $5,091 $5,339 $4,856 - -
Biomedical Imaging 23/ $1,361 $2,083 $2,207 $2,352 $2,495 $2,267 - -
Biotechnology $6,433 $6,556 $6,923 $7,219 $7,655 $6,964 - -
Bipolar Disorder $90 $88 $92 $89 $96 $87 - -
Brain Cancer $310 $332 $360 $359 $393 $350 17,307 0.1% (0.02%)
Brain Disorders $4,577 $5,156 $5,882 $6,954 $7,146 $6,568 - -
Breast Cancer $656 $689 $721 $709 $768 $694 51,816 1.6% (0.08%)
Breastfeeding, Lactation and Breast Milk + $92 $77 $85 $91 $83 - -
Burden of Illness $85 $109 $100 $110 $118 $108 - -
Cachexia $15 $20 $19 $19 $20 $18 11,514 -
Cancer $5,589 $5,980 $6,335 $6,520 $7,120 $6,352 680,869 9.4% (0.22%)
Cancer Genomics $861 $907 $1,031 $1,018 $1,112 $990 - -
Cannabidiol Research $12 $15 $19 $31 $31 $30 - -
Cannabinoid Research $115 $140 $147 $189 $196 $187 - -
Cardiovascular $2,108 $2,197 $2,269 $2,394 $2,496 $2,273 1,529,083 -
Caregiving Research $74 $87 $121 $151 $158 $144 - -
Cerebral Palsy $26 $26 $26 $28 $29 $26 3,529 0.2% (0.06%)**
Cerebrovascular $520 $610 $718 $759 $800 $729 246,352 -
Cervical Cancer $99 $114 $112 $106 $115 $104 4,722 1.0% (0.08%)
Charcot-Marie-Tooth Disease $11 $10 $12 $13 $14 $13 - -
Child Abuse and Neglect Research $29 $29 $41 $43 $45 $41 - -
Childhood Leukemia $151 $177 $197 $178 $198 $172 - -
Childhood Obesity + + $245 $266 $289 $266 - -
Chronic Fatigue Syndrome (ME/CFS) $8 $15 $14 $15 $16 $15 18 -
Chronic Liver Disease and Cirrhosis $293 $285 $324 $351 $369 $341 71,064 -
Chronic Obstructive Pulmonary Disease $97 $100 $111 $112 $117 $107 306,242 6.2% (0.17%)
Chronic Pain 14/ $410 $440 $474 $856 $757 $714 - 30.1% (0.39%)
Climate Change 12/ $5 $7 $10 $10 $10 $9 - -
Climate-Related Exposures and Conditions $156 $193 $223 $235 $257 $235 - -
Clinical Research $12,176 $12,695 $13,870 $15,868 $16,562 $15,117 - -
Clinical Trials and Supportive Activities 17/ $3,476 $3,775 $5,207 $6,058 $6,171 $5,659 - -
Colo-Rectal Cancer $274 $270 $314 $294 $321 $286 61,340 0.6% (0.06%)
Comparative Effectiveness Research $632 $685 $795 $991 $953 $879 - -
Complementary and Integrative Health 27/ $366 $376 $448 $517 $524 $482 - -
Conditions Affecting the Embryonic and Fetal Periods $166 $180 $244 $285 $301 $278 - -
Congenital Heart Disease $111 $119 $117 $131 $138 $126 - -
Congenital Muscular Dystrophy $10 $9 $8 $10 $10 $10 - -
Congenital Structural Anomalies $449 $474 $495 $518 $542 $494 - -
Contraception/Reproduction $419 $437 $496 $547 $572 $522 - -
Cooley's Anemia $18 $18 $18 $22 $23 $21 - -
Cost Effectiveness Research $206 $223 $231 $308 $264 $244 - -
Crohn's Disease $64 $67 $69 $76 $79 $74 1,998 -
Cystic Fibrosis $89 $91 $83 $82 $86 $79 439 -
Data Science + + * $662 $694 $683 0
Dementia $1,054 $1,470 $1,881 $2,326 $2,402 $2,220 - -
Dental/Oral and Craniofacial Disease $518 $541 $575 $613 $640 $579 - -
Depression $410 $438 $500 $578 $603 $553 16,821 -
Diabetes 4/ $1,084 $1,108 $1,039 $1,099 $1,179 $1,090 270,702 9.6% (0.22%)
Dietary Supplements $294 $296 $301 $293 $311 $283 - -
Diethylstilbestrol (DES) $1 $4 $9 $2 $2 $2 - -
Digestive Diseases $1,745 $1,881 $2,242 $2,173 $2,302 $2,106 - -
Digestive Diseases - (Gallbladder) $11 $12 $17 $16 $17 $15 6,208 -
Digestive Diseases - (Peptic Ulcer) $9 $8 $8 $8 $8 $8 6,786 6.2% (0.17%)
Down Syndrome $27 $35 $60 $86 $113 $105 2,364 0.1% (0.04%)**
Drug Abuse (NIDA Only) 5/ $1,049 $1,071 $1,161 $1,621 $1,458 $1,432 - -
Duchenne/ Becker Muscular Dystrophy $33 $30 $32 $34 $35 $32 - -
Dystonia $16 $15 $14 $18 $19 $18 207 -
Eating Disorders 6/ $28 $32 $38 $44 $46 $42 236 -
Eczema / Atopic Dermatitis $29 $32 $35 $35 $36 $34 - -
Emergency Care $129 $139 $146 $166 $165 $153 - -
Emerging Infectious Diseases $2,336 $2,591 $2,767 $2,950 $3,110 $2,877 - -
Emphysema $29 $27 $28 $27 $28 $25 16,471 1.4% (0.08%)
Endocannabinoid System Research $51 $63 $63 $73 $77 $72 - -
Endocrine Disruptors $140 $177 $195 $187 $204 $187 - -
Endometriosis $10 $6 $7 $13 $14 $12 29 -
Epilepsy $153 $154 $184 $188 $203 $185 6,468 1.9% (0.11%)
Estrogen $205 $220 $230 $243 $259 $236 - -
Eye Disease And Disorders Of Vision $847 $882 $963 $985 $1,027 $934 - -
Facioscapulohumeral Muscular Dystrophy $9 $11 $11 $10 $11 $10 - -
Fetal Alcohol Syndrome $29 $28 $34 $34 $36 $32 20 -
Fibroid Tumors (Uterine) $12 $11 $13 $17 $17 $16 89 -
Fibromyalgia $11 $14 $14 $13 $13 $12 566 -
Food Allergies $76 $79 $59 $62 $66 $61 - -
Foodborne Illness 7/ $116 $105 $139 $141 $148 $137 - -
Fragile X Syndrome $44 $46 $38 $37 $39 $36 42 -
Frontotemporal Dementia (FTD) $65 $91 $94 $158 $180 $168 1,798 -
Gene Therapy $265 $266 $315 $391 $421 $372 - -
Gene Therapy Clinical Trials $32 $34 $52 $46 $49 $45 - -
Genetic Testing $165 $148 $151 $183 $200 $170 - -
Genetics $8,070 $8,501 $9,105 $9,864 $10,477 $9,496 - -
Headaches $24 $30 $32 $40 $38 $35 - -
Health Disparities 8/ $3,093 $3,168 $3,178 $3,381 $3,546 $3,235 - -
Health Effects of Household Energy Combustion $17 $17 $20 $20 $22 $20 - -
Health Effects of Indoor Air Pollution $103 $104 $111 $112 $119 $109 - -
Health Services $1,692 $1,770 $1,971 $2,310 $2,328 $2,110 - -
Hearing Loss + + * $163 $169 $154 0
Heart Disease $1,289 $1,370 $1,403 $1,443 $1,504 $1,370 1,221,921 11.5% (0.25%)
Heart Disease - Coronary Heart Disease $419 $444 $444 $421 $438 $399 541,008 4.4% (0.15%)
Hematology $1,317 $1,385 $1,464 $1,474 $1,574 $1,420 - -
Hepatitis $267 $306 $349 $378 $390 $362 - 2.7% (0.13%)
Hepatitis - A $3 $4 $5 $3 $3 $3 91 -
Hepatitis - B $47 $42 $55 $67 $71 $66 1,727 -
Hepatitis - C $107 $114 $129 $150 $149 $140 17,253 -
HIV/AIDS 9/ $3,000 $3,000 $2,995 $3,037 $3,076 $2,813 7,803 -
Hodgkin's Disease $15 $12 $14 $12 $13 $12 1,467 -
Homelessness $17 $17 $18 $17 $18 $16 - -
Homicide and Legal Interventions $1 $1 $2 $3 $3 $3 - -
HPV and/or Cervical Cancer Vaccines $38 $59 $37 $40 $45 $38 - -
Human Fetal Tissue 11/ $103 $98 $115 $109 $116 $107 - -
Human Genome $3,200 $3,274 $3,626 $3,895 $4,134 $3,720 - -
Huntington's Disease $37 $47 $52 $48 $52 $47 1,305 -
Hydrocephalus $8 $11 $10 $10 $11 $10 - -
Hyperbaric Oxygen $3 $6 $5 $4 $5 $4 - -
Hypertension $224 $235 $260 $266 $278 $253 472,428 26.9% (0.35%)
Immunization $1,828 $2,382 $2,127 $2,351 $2,510 $2,278 - -
Immunotherapy + + * $1,436 $1,559 $1,385 0
Infant Mortality $78 $96 $99 $105 $118 $130 - -
Infectious Diseases $5,518 $5,684 $6,024 $6,313 $6,672 $6,161 - -
Infertility $86 $94 $120 $151 $158 $144 - -
Inflammatory Bowel Disease $126 $134 $144 $163 $171 $158 3,275 -
Influenza $263 $301 $340 $384 $423 $423 8,255 -
Injury - Childhood Injuries $47 $60 $145 $169 $179 $163 - -
Injury - Trauma - (Head and Spine) $192 $222 $236 $262 $276 $251 - -
Injury - Traumatic brain injury $105 $116 $133 $134 $143 $130 - -
Injury - Unintentional Childhood Injury $26 $31 $60 $67 $71 $65 - -
Injury (total) Accidents/Adverse Effects $447 $496 $639 $897 $866 $802 - -
Intellectual and Developmental Disabilities (IDD) 15/ $418 $455 $515 $564 $608 $556 - 4.5% (0.29%)**
Interstitial Cystitis $9 $10 $13 $11 $11 $11 36 -
Kidney Disease $574 $592 $598 $649 $671 $621 - 2.1% (0.10%)
Lead Poisoning $9 $10 $10 $11 $12 $11 4 -
Lewy Body Dementia $22 $31 $38 $66 $76 $71 - -
Liver Cancer $83 $90 $113 $127 $139 $124 29,790 0.0% (0.01%)
Liver Disease $635 $691 $802 $851 $890 $819 129,593 1.8% (0.10%)
Lung $1,604 $1,718 $1,849 $1,946 $2,052 $1,874 - -
Lung Cancer $331 $352 $403 $419 $457 $411 156,254 0.3% (0.03%)
Lupus $97 $109 $123 $121 $127 $116 3,419 -
Lyme Disease $28 $22 $30 $32 $34 $53 74 -
Lymphoma $264 $266 $298 $248 $270 $244 26,726 0.3% (0.03%)
Machine Learning and Artificial Intelligence + + * $585 $609 $603 0
Macular Degeneration $99 $100 $105 $124 $128 $117 719 -
Major Depressive Disorder $103 $104 $107 $131 $141 $129 - -
Malaria $183 $192 $202 $196 $208 $192 14 -
Malaria Vaccine $47 $61 $57 $58 $61 $57 - -
Maternal Health + $249 $303 $334 $345 $316 - -
Mental Health $2,454 $2,717 $3,010 $3,296 $3,504 $3,194 - -
Mental Illness $826 $882 $972 $1,063 $1,123 $1,028 - -
Methamphetamine $50 $48 $49 $47 $48 $98 - -
Microbiome + + * $766 $812 $745 0
Migraines $18 $22 $21 $28 $27 $25 - 15.0% (0.28%)
Mind and Body $230 $279 $326 $390 $401 $368 - -
Minority Health 8/ $2,712 $2,934 $3,065 $3,188 $3,378 $3,074 - -
Mucopolysaccharidoses (MPS) $7 $7 $9 $8 $8 $7 70 -
Multiple Sclerosis $97 $111 $112 $111 $118 $109 6,448 -
Muscular Dystrophy $79 $81 $81 $83 $88 $80 1,244 -
Myasthenia Gravis $5 $5 $4 $5 $6 $5 1,837 -
Myotonic Dystrophy $9 $11 $13 $12 $13 $11 - -
Nanotechnology 12/ $398 $444 $540 $650 $686 $623 - -
Neck Pain $1 $2 * $2 $1 $1 - -
Neonatal Respiratory Distress 20/ $52 $62 $62 $79 $71 $65 875 -
Networking and Information Technology R&D 12/ (NITRD) $1,039 $1,149 $1,274 $1,550 $1,592 $1,451 - -
Neuroblastoma $37 $53 $52 $58 $64 $56 - -
Neurodegenerative $2,058 $2,554 $3,085 $3,578 $3,682 $3,392 - -
Neurofibromatosis $29 $31 $31 $36 $39 $36 303 -
Neurosciences $6,460 $7,317 $8,224 $9,468 $10,009 $9,147 - -
Nutrition $1,615 $1,708 $1,830 $1,931 $2,044 $1,878 - -
Obesity $965 $999 $1,055 $1,109 $1,173 $1,080 43,782 30.9% (0.39%)
Opioid Misuse and Addiction 26/ + + $231 $811 $623 $623 48,861 -
Opioids 26/ + + $336 $978 $751 $751 - -
Organ Transplantation $153 $170 $184 $191 $201 $186 - -
Orphan Drug $1,536 $1,653 $1,985 $1,999 $2,150 $1,942 - -
Osteoarthritis $76 $78 $77 $85 $85 $77 - -
Osteogenesis Imperfecta $16 $13 $12 $12 $12 $11 92 -
Osteoporosis $141 $139 $152 $151 $157 $143 7,536 -
Otitis Media $16 $9 $10 $13 $14 $12 78 -
Ovarian Cancer $144 $151 $159 $168 $183 $165 15,346 0.4% (0.07%)
Paget's Disease $2 $2 $3 $2 $3 $2 195 -
Pain Research 26/ $483 $516 $605 $1,011 $924 $924 - -
Pancreatic Cancer $168 $199 $215 $219 $239 $214 46,214 0.1% (0.01%)
Parkinson's Disease $161 $168 $193 $224 $239 $218 47,478 -
Patient Safety $1,048 $1,099 $1,268 $1,454 $1,494 $1,362 - -
Pediatric $3,959 $4,176 $4,499 $4,922 $5,216 $4,759 - -
Pediatric AIDS 9/ $175 $179 $183 $179 $183 $167 - -
Pediatric Cancer $351 $433 $514 $546 $596 $596 - -
Pediatric Cardiomyopathy $27 $30 $24 $25 $26 $24 - -
Pediatric Research Initiative $389 $568 $531 $679 $709 $659 - -
Pelvic Inflammatory Disease $3 $2 $7 $5 $5 $5 334 -
Perinatal Period - Conditions Originating in Perinatal Period $569 $616 $689 $784 $813 $746 14,714 -
Peripheral Neuropathy 18/ $122 $121 $143 $202 $190 $177 - -
Physical Activity $392 $421 $507 $576 $603 $550 - -
Physical Rehabilitation $133 $146 $167 $200 $208 $189 - -
Pick's Disease $8 $8 $8 $11 $12 $11 - -
Pneumonia $127 $114 $134 $146 $153 $141 150,673 -
Pneumonia & Influenza $380 $408 $467 $521 $567 $552 158,630 -
Polycystic Kidney Disease $26 $29 $31 $31 $33 $30 813 -
Post-Traumatic Stress Disorder (PTSD) $89 $101 $112 $138 $138 $127 1,829 -
Precision Medicine $785 $1,152 $1,323 $1,795 $1,891 $1,693 - -
Pregnancy + $319 $419 $487 $515 $473 - -
Prescription Drug Abuse $51 $69 $123 $223 $178 $174 - -
Preterm, Low Birth Weight and Health of the Newborn 21/ $240 $291 $295 $374 $424 $474 5,200 -
Prevention $7,566 $8,052 $8,757 $9,485 $9,884 $9,061 - -
Prostate Cancer $253 $239 $261 $263 $287 $256 42,169 2.4% (0.15%)
Psoriasis $18 $17 $15 $16 $17 $15 480 -
Radiation Oncology $284 $313 $332 $351 $382 $344 - -
Rare Diseases $4,342 $4,613 $5,227 $5,655 $6,040 $5,486 - -
Regenerative Medicine $886 $939 $1,005 $1,069 $1,131 $1,022 - -
Rehabilitation $532 $565 $638 $744 $765 $698 - -
Rett Syndrome $14 $15 $16 $15 $16 $15 64 -
Reye's Syndrome + + * + - - 6 -
Rheumatoid Arthritis $91 $93 $92 $94 $98 $89 9,267 -
Rural Health $295 $259 $338 $541 $527 $478 - -
Sarcopenia $16 $19 $21 $22 $22 $20 - -
Schizophrenia $254 $243 $248 $263 $285 $259 4,434 -
Scleroderma $18 $17 $23 $24 $25 $23 1 -
Screening And Brief Intervention For Substance Abuse $35 $38 $39 $61 $53 $51 - -
Sepsis 15/ $116 $125 $135 $137 $144 $132 203,676 -
Serious Mental Illness $400 $402 $419 $455 $487 $444 - 3.4% (0.13%)
Sexual and Gender Minorities (SGM/LGBT*) 10/ $166 $233 $295 $258 $274 $253 - -
Sexually Transmitted Infections 24/ $260 $322 $354 $354 $379 $345 - -
Sickle Cell Disease $92 $109 $104 $139 $142 $130 973 -
Sleep Research $315 $327 $352 $436 $449 $411 - -
Small Pox $49 $57 $13 $10 $11 $10 - -
Spina Bifida $12 $13 $14 $16 $17 $15 421 -
Spinal Cord Injury $71 $77 $78 $103 $108 $98 1,321 -
Spinal Muscular Atrophy $10 $11 $12 $13 $14 $12 157 -
Stem Cell Research $1,516 $1,646 $1,824 $2,014 $2,129 $1,934 - -
Stem Cell Research - Embryonic - Human $206 $252 $278 $306 $321 $294 - -
Stem Cell Research - Embryonic - Non-Human $146 $129 $130 $140 $148 $135 - -
Stem Cell Research - Induced Pluripotent Stem Cell $374 $421 $507 $607 $640 $585 - -
Stem Cell Research - Induced Pluripotent Stem Cell - Human $335 $382 $468 $563 $593 $542 - -
Stem Cell Research - Induced Pluripotent Stem Cell - Non-Human $56 $59 $68 $74 $79 $72 - -
Stem Cell Research - Nonembryonic - Human $457 $484 $518 $569 $605 $543 - -
Stem Cell Research - Nonembryonic - Non-Human $652 $704 $758 $781 $824 $749 - -
Stem Cell Research - Umbilical Cord Blood/ Placenta $42 $40 $39 $38 $40 $37 - -
Stem Cell Research - Umbilical Cord Blood/ Placenta - Human $33 $35 $36 $36 $39 $35 - -
Stem Cell Research - Umbilical Cord Blood/ Placenta - Non-Human $10 $6 $4 $2 $2 $2 - -
Stroke $308 $331 $348 $350 $372 $340 205,282 -
Substance Abuse 13/ $1,610 $1,636 $1,795 $2,460 $2,283 $2,190 - -
Substance Abuse Prevention $57 $53 $50 $62 $63 $60 - -
Sudden Infant Death Syndrome $16 $13 $7 $11 $12 $11 - -
Suicide $52 $68 $96 $117 $121 $111 47,284 -
Suicide Prevention $33 $35 $51 $60 $65 $59 - -
Teenage Pregnancy $14 $14 $17 $17 $18 $17 - -
Temporomandibular Muscle/Joint Disorder (TMJD) $15 $13 $14 $17 $16 $15 4 -
Therapeutic Cannabinoid Research $28 $36 $37 $46 $48 $46 - -
Tobacco $299 $293 $302 $320 $332 $309 - -
Tobacco Smoke and Health 25/ $298 $293 $284 $301 $312 $290 - 14.0% (0.27%)
Topical Microbicides $99 $91 $86 $84 $89 $83 - -
Tourette Syndrome $5 $6 $10 $11 $12 $11 14 -
Transmissible Spongiform Encephalopathy (TSE) $33 $32 $34 $34 $36 $33 584 -
Transplantation $601 $606 $650 $733 $776 $709 - -
Tuberculosis $290 $347 $403 $488 $516 $478 946 -
Tuberculosis Vaccine $27 $29 $40 $61 $64 $60 - -
Tuberous Sclerosis $26 $21 $23 $25 $27 $24 61 -
Underage Drinking $73 $66 $87 $97 $100 $92 - -
Underage Drinking – Prevention & Treatment (NIAAA Only) 16/ $55 $51 $56 $58 $60 $55 - -
Urologic Diseases $506 $515 $541 $546 $587 $533 - -
Usher Syndrome $16 $18 $18 $17 $18 $16 - -
Uterine Cancer $50 $45 $47 $36 $39 $36 12,362 0.7% (0.07%)
Vaccine Related $1,773 $1,823 $2,022 $2,236 $2,388 $2,166 - -
Vaccine related (AIDS) 9/ $605 $562 $562 $598 $609 $588 - -
Vaginal Cancer $5 $5 $12 $4 $4 $4 - -
Valley Fever $7 $7 $6 $16 $17 $15 - -
Vascular Cognitive Impairment/Dementia $89 $130 $259 $299 $347 $320 - -
Vector-Borne Diseases $546 $557 $630 $611 $647 $642 - -
Violence Against Women $30 $30 $32 $37 $40 $36 - -
Violence Research $111 $115 $131 $141 $149 $136 - -
Vulvodynia $2 $1 $2 $2 $2 $2 - -
West Nile Virus $46 $42 $36 $24 $25 $23 149 -
Women's Health 8/ $4,540 $4,769 $5,048 $4,469 $4,749 $4,333 - -
Youth Violence $46 $50 $46 $48 $51 $47 - -
Youth Violence Prevention $17 $21 $22 $24 $25 $23 - -
[*] The minimum reporting threshold for a specific disease/condition is $500,000. Reporting of $0 does not indicate that no research is being conducted.
[+] Indicates a new category. Funding support data not available prior to the initial year reported.
1/ Name revised in FY 2015 to account for more inclusive definition of research addressing the harms and benefits related to alcohol use.
2/ These categories were established pursuant to Section 230, Division G of the Consolidated and Further Continuing Appropriations Act of 2015 as related to reporting of NIH initiatives supporting the National Alzheimer’s Project Act (NAPA) https://aspe.hhs.gov/national-alzheimers-project-act. The Alzheimer’s Disease Related Dementias (ADRD) category reflects the sum of the three existing RCDC categories: Frontotemporal Dementia, Lewy Body Dementia and Vascular Cognitive Impairment/Dementia – where duplicates are removed. The category Alzheimer’s Disease including Alzheimer’s Disease Related Dementias (AD/ADRD) reflects the sum of the two existing RCDC categories: Alzheimer’s Disease (AD) and the above Alzheimer’s Disease Related Dementias (ADRD) – where duplicates are removed.
3/ Reporting for this category does not follow the standard RCDC process. The total amount reported is consistent with reporting requirements for this category to the U.S. Office of Management & Budget (OMB). The project listing includes non-project or other support costs associated with the annual total for this category. Additional information on this category is available at https://www.niaid.nih.gov/research/biodefense.
4/ Includes research funded from the Type 1 diabetes appropriation.
5/ Reporting for this category does not follow the standard RCDC process. Spending for this category is reported consistent with U.S. Office of National Drug Control Policy (ONDCP) requirements. This category includes only projects funded by NIDA. More information on this area is available at https://www.drugabuse.gov/drugs-abuse. FY 2019 actual and FY 2020/2021 estimates reported in RePORT can differ from levels identified in the FY 2020 Drug Control budget submission for those fiscal years where comparability, rounding or other adjustments have been applied.
6/ Reported total for this category encompasses research for anorexia, bulimia nervosa, binge eating disorders, and eating disorders not otherwise specified.
7/ Name revised in FY 2015 and definition refined. Category merges projects identified as Foodborne Illness with relevant projects from the prior "Food Safety" category. Historical data is maintained in separately to assure that information for predecessor categories is not conflated with the merged category.
8/ Reporting for this category now more closely follows the standard RCDC process compared with the project identification, cost pro-ration, and validation procedures used for FY 2018 and prior fiscal years. Individual Institutes, Centers, and Offices (ICOs) previously classified reportable awards using subjectively-defined criteria and assigned funding based on percentages of female subjects included in the studies. In FY 2019, subject matter experts across ICOs achieved consensus that the allocation of women’s health-related spending should be grounded on scientific relevance and developed new prorating guidance, accordingly. To ensure a robust reporting transition, ICOs applied the new definitions only to the FY 2019 competing projects and retained the previous prorating schemes for the non-competing awards and will gradually roll-out from the inclusion-based approach in the subsequent fiscal years. In conjunction with the described efforts, NIH also instituted the use of an automated Manual Categorization System (MCS) to enhance workflow efficiency and standardize the NIH-wide cost allocation practices.
9/ The total for AIDS research includes both extramural and intramural research (including research management and support, Management Fund, and Service & Supply Fund), buildings and facilities, research training, and program evaluation, as well as research on the many HIV-associated co-infections and co-morbidities, including TB, hepatitis C, and HIV-associated cancers. It also includes all the basic science underlying this research. Other RCDC categories are not reported this way. As a result, the total for AIDS-related research is not comparable to spending reported for other RCDC diseases. More information on this area is available at https://www.oar.nih.gov/hiv-policy-and-research.
10/ This category includes projects that are focused on basic, pre-clinical, clinical, biomedical, health services, behavioral, and social research relevant to sexual and gender minority (SGM) populations. The SGM population – which historically includes LGBT, is asterisked to recognize the diversity in membership as well as sensitivities associated with the variety of descriptive names in use by the medical communities and general public. This research pertains to people whose sexual orientation is not exclusively heterosexual, i.e. lesbian, gay, and bisexual or pansexual persons. Research projects can likewise focus on individuals whose gender identity differs from the sex originally assigned to them at birth, transgender (male-to-female or female-to-male), bi gender, gender non-conforming or gender variant, or who may not self-identify as LGBT (such as queer, questioning, two-spirit, asexual, etc.). Research also can cover individuals who are born with conditions in which development of chromosomal, gonadal, or anatomic sex is atypical, i.e. people who identify themselves as intersex or with differences/disorders of sex development (DSD). DSD can include, but are not limited to: Y chromosome aneuploidy, congenital adrenal hyperplasia, complete androgen insensitivity, partial androgen insensitivity, gonadal dysgenesis, mixed gonadal dysgenesis, hypospadias, Klinefelter syndrome, Turner syndrome, 5aRD2 deficiency, aromatase defects, MRKH syndrome and gynecomastia. For further information please refer to the SGMRO website.
11/ Reporting for this category does not follow the standard RCDC process. This category uses a non-standard approach involving subject matter expert reviews of manually collected project listings. The definition used to compile the project list was revised for clarification in FY 2016.
12/ The data provided reflects funding amounts reported by the NIH RCDC process for this category. Actual and estimate levels presented on this site supersede estimates detailed in OMB MAX DE application tables that may have been based on preliminary funding support information.
13/ Reporting for this category does not follow the standard RCDC process. This category includes all spending reported under the Drug Abuse category as well as projects categorized under the broader area of Substance Abuse. These are project listings only. More information on this area is available at https://www.drugabuse.gov/drugs-abuse.
14/ Name revised in FY 2018 from "Pain Conditions – Chronic."
15/ Name revised in FY 2013 to reflect current scientific terminology.
16/ Reporting for this category does not follow the standard RCDC process. Spending for this category is reported consistent with U.S. Office of National Drug Control Policy (ONDCP) requirements. This category includes only projects funded and administered by NIAAA. This category represents a subset of spending reported under the RCDC Underage Drinking category and involves manual review of the project listing by subject matter experts. More information on this area is available at https://www.niaaa.nih.gov/research/major-initiatives/underage-drinking-research-initiative. Actuals or estimates displayed in RePORT can differ from levels identified in the Drug Control budget submission to ONDCP for those fiscal years where either comparable, rounding or other adjustments have been applied or historical data was refined.
17/ Name revised in FY 2015 from "Clinical Trials".
18/ Name revised in FY 2015 from "Neuropathy".
19/ Estimates of United States disease burden are provided as mortality and prevalence figures for calendar year 2017. Figures for mortality data are drawn from the National Vital Statistics System (NVSS), and indicate the number of deaths in which a particular disease or condition was mentioned on a deceased individual's death certificate. Prevalence figures are drawn from National Health Interview Survey (NHIS) responses and report the percentage of respondents who indicated that they were affected by a particular health condition. Standard error, a measure of the uncertainty in the estimate, is presented in parentheses alongside the prevalence estimate. Estimates of mortality and prevalence are not available for all NIH spending categories. Further descriptions of these disease statistics can be found here.
20/ Name revised in FY 2016 from "Perinatal - Neonatal Respiratory Distress Syndrome".
21/ Name revised in FY 2016 from "Perinatal - Birth - Preterm (LBW)".
22/ Name revised in FY 2017 from "American Indians/Alaskan Natives".
23/ Name revised in FY 2017 from "Diagnostic Radiology".
24/ Name revised in FY 2018 from "Sexually Transmitted Diseases/Herpes".
25/ Name revised in FY 2018 from "Smoking and Health".
26/ The FY 2019 actuals include obligations of over $400 million from FY 2018 carryover to support the Helping to End Addiction Long-term (HEAL) Initiative. These amounts, combined with obligations from FY 2019 annual appropriations, have a significant impact on the Opioids, Opioids Misuse and Addiction, and Pain Research categories. This is a one-time spike in FY 2019 actuals, and FY 2020 estimates are proportionately lower since they reflect a single year of funding.
27/ Name revised in FY 2019 from "Complementary and Alternative Medicine".
[**] indicates that prevalence for this particular disease or condition was measured only in children <18


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Page Last Updated on June 30, 2018

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