Biennial Report of the Director

Appendix I: Acronmys


ABCA1

ATP-binding Cassette Transporter

ACC

Autism Coordinating Committee

ACCORD

Action to Control Cardiovascular Risk in Diabetes

ACE

Autism Centers of Excellence

ACTTION

Analgesic Clinical Trial Translations, Innovations, Opportunities, and Networks

AD

Alzheimer’s Disease

ADC

Alzheimer’s Disease Center

ADCS

Alzheimer’s Disease Cooperative Study

ADGC

Alzheimer’s Disease Genetics Consortium

ADHD

Attention-deficit/Hyperactivity Disorder

ADNI

Alzheimer’s Disease Neuroimaging Initiative

AHEAD

Action for Health in Diabetes

AHRQ

Agency for Healthcare Research and Quality

AIDS

Acquired Immunodeficiency Syndrome

ALL

Acute Lymphoblastic Leukemia

ALS

Amyotrophic Lateral Sclerosis

AMA

American Medical Association

AMD

Age-related Macular Degeneration

ARIC

Atherosclerosis Risk in Communities

Army STARRS

Army Study to Assess Risk and Resilience in Service Members

ARRA

American Recovery and Reinvestment Act

ASD

Autism Spectrum Disorder

BAER

Basal Adverse Event Report

BCBC

Beta Cell Biology Consortium

BCERC

Breast Cancer and the Environment Research Centers

BCERPs

Breast Cancer and the Environment Research Programs

BChE

Butyrylcholinesterase

BIRCWH

Building Interdisciplinary Careers in Women’s Health

BIRN

Biomedical Informatics Research Network

BIRT

Building Interdisciplinary Research Teams

BLSA

Baltimore Longitudinal Study of Aging

BMD

Becker Muscular Dystrophy

BMI

Body Mass Index

BMSC

Bone Marrow Stromal Cells

BP

Blood Pressure

BPA

Bisphenol A

BPH

Benign Prostatic Hyperplasia

BTRC

Biomedical Technology Research Center

CABANA

Catheter Ablation versus Antiarrhythmic Drug Therapy for Atrial Fibrillation

caBIG®

NCI cancer Biomedical Informatics Grid®

CAD

Coronary Artery Disease

CADET

Centers for Advanced Diagnostics and Experimental Therapeutics in Lung Diseases

caHUB

Cancer Human Biobank

CAM

Complementary and Alternative Medicine

CAMUS

Complementary and Alternative Medicine for Urological Symptoms

CARDIA

Coronary Artery Risk Development in Young Adults

CARe

Candidate Gene Association Resource

CATT

Comparison of AMD Treatment Trials

CBT

Cognitive Behavioral Therapy

CC

NIH Clinical Center

CCOP

Community Clinical Oncology Program

CDC

Centers for Disease Control and Prevention

CDEs

Common Data Elements

CE

Continuing Education

CEBS

Chemical Effects in Biological Systems

CEED

Center of Excellence in Eliminating Disparities

CER

Comparative effectiveness research

CERC

Centers of Excellence for Research on CAM

CERT

Community-Empowered Research Training

CETP

Cholesterylester Transfer Protein

CF

Cystic Fibrosis

CFH

Complement Factor H

CFRD

Cystic Fibrosis Related Diabetes

CFS

Chronic Fatigue Syndrome

CFS

Cleveland Family Study

CFSAC

Chronic Fatigue Syndrome Advisory Committee

CFTR

CF Transmembrane Conductance Regulator

CHARGE

Childhood Autism Risks from Genetics and Environment

CHI

Center for Human Immunology, Autoimmunity, and Inflammation

CHS

Cardiovascular Health Study

CIRT

Cardiovascular Inflammation Reduction Trial

CIT

Center for Information Technology

CJ-DATS

Criminal Justice-Drug Abuse Treatment Studies

CKD

Chronic Kidney Disease

CKiD

Chronic Kidney Disease in Children

CMD

Congenital Muscular Dystrophies

CMS

Centers for Medicare & Medicaid Services

CNRM

Center for Neuroscience and Regenerative Medicine

CNS

Centers for Neurodegeneration Science

CNV

Choroidal Neovascularization

COAG

Clarification of Optimal Anticoagulation through Genetics

COE

Centers of Excellence

COPD

Chronic Obstructive Pulmonary Disease

COPTR

Childhood Obesity Prevention and Treatment Research

CORAL

Cardiovascular Outcomes in Renal Atherosclerotic Lesions

CORE

Centers for Cardiovascular Outcomes Research

CORT

Centers of Research Translation

CP/CPPS

Chronic Prostatitis/Chronic Pelvic Pain Syndrome

CPAG

Coalition of Patient Advocacy Groups

CPEA

Collaborative Programs of Excellence in Autism

CRADA

Cooperative Research and Development Agreement

CRCNS

Collaborative Research in Computational Neuroscience

CREST

Carotid Endarterectormy for Carotid Disease

CRIC

Chronic Renal Insufficiency Cohort

CRN

Cancer Research Network

CRP

C-reactive Protein

CSR

Center for Scientific Review

CT

Computer-assisted Tomography

CTC

Circulating Tumor Cells

CTC

Communities That Care

CTN

Clinical Trials Network

CTOT

Clinical Trials in Organ Transplantation

CTOT-C

Clinical Trials in Organ Transplantation in Children

C-TRIP

Cardiac Translational Research Implementation Program

CTSA

Clinical Translation Science Awards

CTSI

Clinical Translation Science Institutes

CVD

Cardiovascular Disease

CVRG

CardioVascular Research Grid

CVRN

Cardiovascular Research Network

dbGaP

Database of Genotype and Phenotype

DCCT

Diabetes Control and Complications Trial

DIAN

Dominantly Inherited Alzheimer’s Network

DMCC

Data Management and Coordinating Center

DMD

Duchenne Muscular Dystrophy

DME

Diabetic Macular Edema

DNA

Deoxyribonucleic Acid

DoD

Department of Defense

DOHaD

Developmental Origins of Health and Disease

DPCPSI

Division of Program Coordination, Planning, and Strategic Initiatives

DPP

Diabetes Prevention Program

DPPOS

Diabetes Prevention Program Outcome Study

DRD4

D4 Receptor Gene

DTE

Device Thrombogenicity Emulator

E. coli.

Escherichia coli

EARLI

Early Autism Risk Longitudinal Investigation

EARLY

Early Adult Reduction of Weight through Lifestyle intervention

ED

Department of Education

EDIC

Epidemiology of Diabetes Interventions and Complications Study

EDRN

Early Detection Research Network

EITCs

Education and Information Transfer Cores

EKSIDDRCs

Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Centers

ELSI

Ethical, Legal and Social Implications

eMERGE

Electronic Medical Records and Genomics

EMR

Electronic Medical Record

ENaC

Epithelial Sodium Channel

ENCODE

ENCyclopedia Of DNA Elements

EPA

Environmental Protection Agency

EPR

Environmental Polymorphism Registry

F award

Fellowship

FAR

Federal Acquisition Regulation

FDA

Food and Drug Administration

FDAAA

Food and Drug Administration Amendments Act

FHS

Framingham Heart Study

FIC

John E. Fogarty International Center

FITBIR

Federal Interagency TBI Research

fMRI

Functional Magnetic Resonance Imaging

FOA

Funding Opportunity Announcement

FREEDOM

Future Revascularization Evaluation in Patients with Diabetes Mellitus: Optimal management of Multivessel Disease

FSGS

Focal Segmental Glomerulosclerosis

FSHD

Facioscapulohumeral muscular dystrophy

FY

Fiscal Year

GA

Geographic Atrophy

GAD

Glutamic Acid Decarboxylase

GDM

Gestational Diabetes Mellitus

GENSAT

Gene Expression Nervous System Atlas

GERD

Gastroesophageal Reflux Disease

GI

Gastrointestinal

GPRA

Government Performance and Results Act

GUDMAP

GenitoUrinary Development Molecular Anatomy Project

GWAS

Genome-Wide Association Studies

HANDLS

Healthy Aging in Neighborhoods of Diversity across the Life Span

HapMap

Haplotype Map 

HbA1C

Hemoglobin A1C

HbF

Fetal Hemoglobin

HDAC2

Histone Deacetylase 2

HDACs

Histone Deacetylases

HGP

Human Genome Project

HHC

Health and Hospitals Corporation

HHS

Department of Health and Human Services

HIFU

High-Intensity Focused Ultrasound

HIPAA

Health Insurance Portability and Accountability Act

HIV

human immunodeficiency virus

HIVAN

HIV-associated Nephropathy

HMO

Health Maintenance Organization

HOMD

Human Oral Microbiome Database

HPV

Human Papillomavirus

HRS

Health and Retirement Study

HRSA

Health Resources and Services Administration

IACC

Interagency Autism Coordinating Committee

IAN

Interactive Autism Network

IBCs

Intracellular Bacterial Communities

IBS

Irritable Bowel Syndrome

IC/PBS

Interstitial Cystitis/Painful Bladder Syndrome

ICAC

Inner-City Asthma Consortium

ICBP

Integrative Cancer Biology Program

ICs

Institutes and Centers

IDDs

Intellectual and Developmental Disabilities

IDE

Investigational Device Exemption

IGI

Image-guided Interventions

IHS

Indian Health Service

IND

Investigational New Drug

INTERMACS

Interagency Registry for Mechanically Assisted Circulatory Support

IOM

Institute of Medicine

iPOP

Integrative Personal Omics Profile

IPRCC

Interagency Pain Research Coordinating Committee

iPS

Induced Pluripotent Stem Cell

IRB

Institutional Review Board

ISCHEMIA

Ischemic Heart Disease

ISS

International Space Station

ITP

Interventions Testing Program

JHS

Jackson Heart Study

K award

Career Development Award

LABS

Longitudinal Assessment of Bariatric Surgery

LAM

Lymphangioleiomyomatosis

LGMDs

Limb-girdle Muscular Dystrophies

LIPC

Hepatic Lipase Gene

LOTT

Long-term Oxygen Treatment Trial

LPL

Lipoprotein Lipase

LPS

Lipopolysaccharides

LTA4H

Leukotriene A4 Hydrolase

LUTD

Lower Urinary Tract Dysfunction

MAPP

Multidisciplinary Approach to the Study of Chronic Pelvic Pain

MD

Muscular dystrophies

MDA

Malondialdehyde

MDS

Minimum Data Set

ME

Myalgic Encephalomyelitis

ME/CFS

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

MESA

Multi-Ethnic Study of Atherosclerosis

MHRN

Mental Health Research Network

MIDAS

Models of Infectious Disease Agent Study

miRNA

microRNA

MLV

Murine Leukemia Virus

modENCODE

Model ENCODE Project

MRI

Magnetic Resonance Imaging

MRS

Magnetic Resonance Spectroscopy

MS

Multiple Sclerosis

MTF

Monitoring the Future

NACC

National Alzheimer's Coordinating Center

NAS

National Academy of Sciences

NASA

National Aeronautics and Space Administration

NASH

Nonalcoholic Steatohepatitis

NCBC

National Centers for Biomedical Computing

NCCAM

National Center for Complementary and Alternative Medicine

NCCOR

National Collaborative on Childhood Obesity Research

NCI

National Cancer Institute

NCRAD

National Cell Repository for Alzheimer’s Disease

NCRR

National Center for Research Resources

NCS

National Children’s Study

NDAR

National Database for Autism Research

NDEP

National Diabetes Education Program

NEI

National Eye Institute

NESARC

National Epidemiologic Survey on Alcohol and Related Conditions

NET-PD

NIH Exploratory Trials in PD

NExT

NCI Experimental Therapeutics Program

NHANES

National Health and Nutrition Examination Survey

NHATS

National Health and Aging Trends Study

NHGRI

National Human Genome Research Institute

NHLBI

National Heart, Lung, and Blood Institute

NIA

National Institute on Aging

NIAAA

National Institute on Alcohol Abuse and Alcoholism

NIAID

National Institute of Allergy and Infectious Diseases

NIAMS

National Institute of Arthritis and Musculoskeletal and Skin Diseases

NIBIB

National Institute of Biomedical Imaging and Bioengineering

NICHD

Eunice Kennedy Shriver National Institute of Child Health and Human Development

NIDA

National Institute on Drug Abuse

NIDCD

National Institute on Deafness and Other Communication Disorders

NIDCR

National Institute of Dental and Craniofacial Research

NIDDK

National Institute of Diabetes and Digestive and Kidney Diseases

NIEHS

National Institute of Environmental Health Sciences

NIF

Neuroscience Information Framework

NIGMS

National Institute of General Medical Sciences

NIH

National Institutes of Health

NIH CRM

NIH Center for Regenerative Medicine

NIMH

National Institute of Mental Health

NIMHD

National Institute on Minority Health and Health Disparities

NINDS

National Institute of Neurological Disorders and Stroke

NINR

National Institute of Nursing Research

NIST

National Institute of Standards and Technology

NITRC

Neuroimaging Informatics Tools and Resources Clearinghouse

NKDEP

National Kidney Disease Education Program

NLM

National Library of Medicine

nm

Nanometers

NMR

Nuclear Magnetic Resonance

NRF2

Nuclear Factor Erythroid 2–Related Factor 2

NRSA

Ruth L. Kirschstein National Research Service Award

NYU

New York University

OAIC

Older Americans Independence Center

OASH

Office on Women's Health, Office of the Assistant Secretary for Health

OBSSR

Office of Behavioral and Social Sciences Research

OCPL

Office of Communications and Public Liaison

OER

Office of Extramural Research

OIR

Office of Intramural Research

OMAR

Office of Medical Applications of Research

OPPERA

Prospective Evaluation and Risk Assessment

OppNet

Basic Behavioral and Social Science Opportunity Network

ORBIT

Obesity Related Behavioral Intervention Trials

ORDR

Office of Rare Diseases Research

ORWH

Office of Research on Women's Health

P award

Program Projects or Centers Grants

PA 

Program Announcement

PBRNs

Practice-based Research Networks

PCBs

polychlorinated biphenyls

PD

Parkinson’s Disease

PedETrol

Pediatric ICUs at Emory Children’s Center Glycemic Control

PEPH

Partnerships for Environmental Public Health

PET

Positron Emission Tomography

PFDN

Pelvic Floor Disorders Network

PFINDR

Phenotype Finder IN Data Resources

PGP

Proline-glycine-proline

PGRN

Pharmacogenetics Research Network

PharmGKB

Pharmacogenomics Knowledge Base

PHS

Public Health Service

PMC

PubMed Central

POATS

Prescription Opioid Addiction Treatment Study

POWER

Practice-Based Opportunity for Promotion of Weight Reduction

PPAR-γ

Peroxisome Proliferator-activated Receptor Gamma

PQ 

Provocative Questions

PROMIS

Patient-Reported Outcomes Measurement Information System

PumpKIN

Pumps for Kids, Infants, and Neonates

QIBA

Quantitative Imaging Biomarkers Alliance

R award

Research Grant

RAAS

Renin-Angiotensin-Aldosterone System

RAID

Ranolazine Implantable Cardioverter-Defibrillator

RCMAR

Resource Centers for Minority Aging Research

RCMI

Research Centers in Minority Institutions

RDCRN

Rare Diseases Clinical Research Network

REGARDS

Reasons for Geographic and Racial Differences in Stroke

REMBRANDT

Repository of Molecular Brain Neoplasia Data

REVIVE IT

Randomized Evaluation of VAD Intervention before Inotropic Therapy

RICE

Rand IC Epidemiology

RIVUR

Randomized Intervention for Vesicoureteral Reflux

RNA

Ribonucleic Acid

ROMICAT II

Rule Out Myocardial Infarction/Ischemia Using Computer Assisted Tomography

RPE

Retinal Pigment Epithelium

SBIR

Small Business Innovation Research

SBIRT

Screening, Brief Intervention, and Referral

SCI

Spinal Cord Injury

SCORs 

Specialized Centers of Interdisciplinary Research

SEER

Surveillance Epidemiology and End Results

SEP

Special Emphasis Panel

SES

Socioeconomic Status

SHHS

Sleep Heart Health Study

SHINE

Stimulating Hematology Investigation: New Endeavors

SIDS

Sudden Infant Death Syndrome

siRNA

Short-interfering RNA

SNP

Single-nucleotide Polymorphism

SOD3

Superoxide Dismutase

SPIROMICS

SubPopulations and InteRmediate Outcome Measures in COPD Study

SPORE

Specialized Programs of Research Excellence

SPOTRIAS

Specialized Program of Translational Research in Stroke

SPRINT

Systolic Blood Pressure Intervention

SRG

Scientific Review Group

STEP-UP

Short-Term Education Program for Underrepresented Persons

STICH

Surgical Treatment for Ischemic Heart Failure

STTR

Small Business Technology Transfer

SUI

Stress Urinary Incontinence

suPAR

Serum-soluble Urokinase Receptor

T award

Research Training Award

TARGET

Therapeutically Applicable Research to Generate Effective Treatments

TBI

Traumatic Brain Injury

TCGA

The Cancer Genome Atlas

TECS

Trial of Euglycemia in Cardiac Surgery

TEDDY

The Environmental Determinants of Diabetes in the Young

THAPCA

Therapeutic Hypothermia after Pediatric Cardiac Arrest

TIMP3

Metalloproteinase Inhibitor 3

TMJD

Temporomandibular Joint Disorders

TODAY

Treatment Options for Type 2 Diabetes in Adolescents and Youth

TOPCAT

Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist

tPA

Tissue Plasminogen Activator

T-R01

Transformative R01

TRND

Therapeutics for Rare and Neglected Diseases

UCD

Urea Cycle Defect

UDA

Urologic Diseases in America

UDP

Undiagnosed Diseases Program

UDS

Uniform Data Set

UMLS

Unified Medical Language System

USDA

United States Department of Agriculture

UTI

Urinary Tract Infection

VCRC

Vasculitis Clinical Research Consortium

MDCRC

Muscular Dystrophy Cooperative Research Center

WHO

World Health Organization

WIN

Weight-control Information Network

XMRV

Xenotropic murine leukemia virus-related virus

ZFNs

Zinc-finger Nucleases