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Estimates of Funding for Various Research, Condition, and Disease Categories (RCDC)


Table Published: February 10, 2016

The table below displays the annual support level for various research, condition, and disease categories based on grants, contracts, and other funding mechanisms used across the National Institutes of Health (NIH).

At the request of Congress, the NIH embarked on a process to provide better consistency and transparency in the reporting of its funded research. This new process, implemented in 2008 through the Research, Condition, and Disease Categorization (RCDC) system, uses sophisticated text data mining (categorizing and clustering using words and multiword phrases) in conjunction with NIH-wide definitions used to match projects to categories. RCDC use of data mining improves consistency and eliminates the wide variability in defining the research categories reported. The definitions are a list of terms and concepts selected by NIH scientific experts to define a research category. The research category levels represent the NIH’s best estimates based on the category definitions. For a federal source of case-by-case burden data on a broad variety of diseases, conditions, and populations, please see the Centers for Disease Control and Prevention (CDC) FastStats site.

The NIH does not expressly budget by category. The annual estimates reflect amounts that change as a result of science, actual research projects funded, and the NIH budget. The research categories are not mutually exclusive. Individual research projects can be included in multiple categories so amounts depicted within each column of this table do not add up to 100 percent of NIH-funded research.

The table shows historical data for FY 2012 through FY 2015. The FY 2016-2017 estimates are based on RCDC actual data.

Total Number of Research/Disease Areas: 265

Click here for instructions on how to use the data table below.

Research/Disease Areas
(Dollars in millions and rounded)
FY 2012ActualFY 2013ActualFY 2014ActualFY 2015ActualFY 2016EstimatedFY 2017Estimated
Acquired Cognitive Impairment + + + $798 $832 $832
Acute Respiratory Distress Syndrome $98 $95 $85 $108 $112 $112
Adolescent Sexual Activity $76 $70 $68 $85 $88 $88
Agent Orange & Dioxin $8 $10 $8 $9 $9 $9
Aging $2,593 $2,429 $2,556 $2,698 $2,807 $2,807
Alcoholism, Alcohol Use and Health 1/ $455 $437 $475 $473 $494 $494
Allergic Rhinitis (Hay Fever) $7 $9 $6 $5 $5 $5
ALS $44 $39 $48 $49 $52 $52
Alzheimer's Disease $503 $504 $562 $589 $910 $910
Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD) 2/ + + + $631 $991 $991
Alzheimer's Disease Related Dementias (ADRD) 2/ + + + $120 $161 $161
American Indians / Alaska Natives $170 $160 $166 $181 $190 $190
Anorexia $14 $11 $11 $10 $10 $10
Anthrax $84 $70 $67 $53 $56 $56
Antimicrobial Resistance $377 $325 $277 $310 $413 $413
Anxiety Disorders + + + $156 $163 $163
Aphasia $24 $24 $24 $25 $26 $26
Arctic $23 $19 $16 $14 $14 $14
Arthritis $258 $231 $239 $214 $222 $222
Assistive Technology $237 $220 $228 $246 $258 $258
Asthma $229 $207 $241 $281 $289 $289
Ataxia Telangiectasia $11 $11 $8 $7 $8 $8
Atherosclerosis $477 $374 $375 $386 $402 $402
Attention Deficit Disorder (ADD) $60 $49 $44 $41 $43 $43
Autism $192 $186 $188 $208 $216 $216
Autoimmune Disease $867 $821 $822 $821 $850 $850
Basic Behavioral and Social Science $1,215 $1,172 $1,234 $1,610 $1,683 $1,683
Batten Disease $4 $5 $5 $5 $6 $6
Behavioral and Social Science $3,682 $3,535 $3,688 $3,762 $3,924 $3,924
Biodefense 3/ $1,791 $1,692 $1,746 $1,736 $1,866 $1,866
Bioengineering $3,498 $3,234 $3,329 $3,540 $3,697 $3,697
Biotechnology $6,089 $5,698 $5,889 $6,018 $6,281 $6,281
Bipolar Disorder + + + $80 $83 $83
Brain Cancer $281 $280 $289 $298 $310 $310
Brain Disorders $3,968 $3,708 $3,894 $3,916 $4,108 $4,108
Breast Cancer $800 $657 $682 $674 $699 $699
Burden of Illness $84 $72 $73 $80 $82 $82
Cancer $5,621 $5,274 $5,392 $5,389 $5,652 $6,332
Cannabidiol Research + + + $9 $9 $9
Cannabinoid Research + + + $111 $115 $115
Cardiovascular $2,040 $1,964 $1,950 $1,991 $2,072 $2,072
Cerebral Palsy $42 $18 $21 $20 $21 $21
Cervical Cancer $112 $98 $116 $99 $103 $106
Charcot-Marie-Tooth Disease $13 $11 $14 $14 $14 $14
Child Abuse and Neglect Research $32 $30 $30 $27 $28 $28
Childhood Leukemia $77 $67 $105 $155 $161 $167
Chronic Fatigue Syndrome (ME/CFS) $5 $5 $5 $6 $7 $7
Chronic Liver Disease and Cirrhosis $288 $282 $293 $295 $307 $307
Chronic Obstructive Pulmonary Disease $101 $102 $107 $97 $100 $100
Climate Change 12/ $8 $8 $6 $7 $7 $7
Climate-Related Exposures and Conditions 14/ $157 $137 $131 $150 $154 $154
Clinical Research $10,951 $10,604 $11,087 $11,366 $11,867 $11,867
Clinical Trials and Supportive Activities 17/ $3,208 $3,155 $3,221 $3,136 $3,266 $3,266
Colo-Rectal Cancer $302 $281 $271 $309 $321 $331
Comparative Effectiveness Research $597 $559 $610 $587 $611 $611
Complementary and Alternative Medicine $493 $380 $367 $337 $348 $348
Conditions Affecting the Embryonic and Fetal Periods 15/ $165 $151 $175 $200 $204 $204
Congenital Structural Anomalies $0 $0 $0 $404 $420 $420
Contraception/Reproduction $448 $408 $394 $424 $434 $434
Cooley's Anemia $20 $15 $18 $15 $16 $16
Cost Effectiveness Research $78 $82 $70 $175 $182 $182
Crohn's Disease $76 $61 $65 $66 $69 $69
Cystic Fibrosis $86 $78 $77 $80 $83 $83
Dementia $0 $650 $704 $721 $753 $753
Dental/Oral and Craniofacial Disease $516 $480 $483 $493 $512 $512
Depression $429 $415 $396 $390 $406 $406
Diabetes 4/ $1,061 $1,007 $1,011 $1,010 $1,044 $1,044
Diagnostic Radiology $1,090 $1,079 $1,078 $1,272 $1,320 $1,320
Diethylstilbestrol (DES) $3 $1 $1 $1 $1 $1
Digestive Diseases $1,719 $1,575 $1,607 $1,684 $1,754 $1,754
Digestive Diseases - (Gallbladder) $11 $10 $9 $8 $8 $8
Digestive Diseases - (Peptic Ulcer) $20 $19 $15 $16 $16 $16
Down Syndrome $20 $18 $18 $24 $25 $25
Drug Abuse (NIDA Only) 5/ $1,052 $993 $1,018 $1,016 $1,051 $1,051
Duchenne/ Becker Muscular Dystrophy $34 $33 $32 $30 $32 $32
Dystonia $14 $13 $12 $14 $15 $15
Eating Disorders 6/ $34 $31 $30 $31 $32 $32
Eczema / Atopic Dermatitis + + + $27 $28 $28
Emergency Care + + + $122 $128 $128
Emerging Infectious Diseases $2,153 $1,804 $1,930 $2,053 $2,200 $2,200
Emphysema $20 $24 $27 $28 $29 $29
Endometriosis $9 $7 $7 $10 $11 $11
Epilepsy $156 $129 $154 $138 $145 $145
Estrogen $221 $218 $203 $194 $201 $201
Eye Disease And Disorders Of Vision $841 $774 $824 $779 $815 $815
Facioscapulohumeral Muscular Dystrophy $5 $5 $7 $8 $9 $9
Fetal Alcohol Syndrome $32 $33 $34 $32 $33 $33
Fibroid Tumors (Uterine) $14 $10 $9 $10 $10 $10
Fibromyalgia $13 $11 $10 $8 $9 $9
Food Allergies $31 $36 $35 $39 $41 $41
Foodborne Illness 7/ $257 $229 $232 $105 $109 $109
Fragile X Syndrome $27 $30 $36 $38 $40 $40
Frontotemporal Dementia (FTD) $26 $32 $37 $36 $37 $37
Gene Therapy $256 $226 $253 $238 $248 $250
Gene Therapy Clinical Trials $15 $15 $26 $23 $24 $24
Genetic Testing $255 $272 $231 $161 $167 $167
Genetics $7,632 $7,144 $7,324 $7,480 $7,826 $7,879
Global Warming Climate Change $6 $6 $4 $4 $4 $4
Headaches $24 $25 $24 $24 $25 $25
Health Disparities 8/ $2,740 $2,722 $2,734 $2,825 $2,952 $2,952
Health Effects of Household Energy Combustion + + + $14 $14 $14
Health Effects of Indoor Air Pollution + + + $103 $106 $106
Health Services $1,317 $1,262 $1,342 $1,437 $1,500 $1,500
Heart Disease $1,278 $1,230 $1,224 $1,262 $1,314 $1,314
Heart Disease - Coronary Heart Disease $468 $404 $421 $426 $444 $444
Hematology $1,091 $1,020 $1,189 $1,217 $1,264 $1,264
Hepatitis $210 $195 $251 $262 $273 $273
Hepatitis - A $2 $2 $3 $4 $4 $4
Hepatitis - B $51 $48 $48 $42 $43 $43
Hepatitis - C $112 $101 $111 $96 $100 $100
HIV/AIDS 9/ $3,074 $2,898 $2,978 $3,000 $3,000 $3,000
Hodgkin's Disease $21 $13 $14 $16 $16 $16
Homelessness $10 $11 $14 $15 $16 $16
Homicide and Legal Interventions $1 $0 $0 $1 $1 $1
HPV and/or Cervical Cancer Vaccines $26 $25 $38 $31 $32 $32
Human Fetal Tissue 11/ $71 $67 $76 $80 $84 $84
Human Genome $2,271 $2,473 $2,701 $2,891 $3,025 $3,025
Huntington's Disease $65 $55 $50 $39 $39 $39
Hydrocephalus $7 $6 $5 $6 $6 $6
Hyperbaric Oxygen $2 $1 $2 $3 $3 $3
Hypertension $215 $222 $216 $214 $222 $222
Immunization $1,733 $1,656 $1,607 $1,617 $1,669 $1,669
Infant Mortality + + + $75 $78 $78
Infant Mortality/ (LBW) $287 $253 $268 $293 $302 $302
Infectious Diseases $3,867 $4,887 $5,002 $5,032 $5,249 $5,249
Infertility $74 $78 $76 $72 $73 $73
Inflammatory Bowel Disease $121 $114 $125 $128 $134 $134
Influenza $251 $304 $262 $280 $285 $285
Injury - Childhood Injuries $37 $37 $35 $39 $41 $41
Injury - Trauma - (Head and Spine) $171 $183 $216 $197 $208 $208
Injury - Traumatic brain injury $79 $88 $87 $93 $99 $99
Injury - Unintentional Childhood Injury $22 $20 $22 $23 $24 $24
Injury (total) Accidents/Adverse Effects $366 $367 $404 $399 $418 $418
Intellectual and Developmental Disabilities (IDD) 15/ $355 $343 $356 $382 $397 $397
Interstitial Cystitis $10 $10 $9 $10 $11 $11
Kidney Disease $556 $551 $549 $564 $586 $586
Lead Poisoning $8 $8 $7 $7 $8 $8
Lewy Body Dementia + + $15 $15 $16 $16
Liver Cancer $73 $71 $74 $85 $89 $89
Liver Disease $632 $594 $605 $616 $642 $642
Lung $1,286 $1,230 $1,329 $1,619 $1,678 $1,678
Lung Cancer $233 $208 $254 $349 $362 $362
Lupus $108 $92 $99 $90 $93 $93
Lyme Disease $25 $20 $23 $24 $25 $25
Lymphoma $213 $233 $251 $270 $281 $281
Macular Degeneration $101 $98 $82 $82 $85 $85
Major Depressive Disorder + + + $95 $99 $99
Malaria $152 $147 $169 $163 $171 $171
Malaria Vaccine $40 $34 $36 $44 $46 $46
Mental Health $2,287 $2,174 $2,213 $2,263 $2,381 $2,381
Methamphetamine $69 $68 $63 $58 $60 $60
Migraines $18 $19 $20 $20 $20 $20
Mind and Body $533 $210 $211 $217 $226 $226
Minority Health 8/ $2,487 $2,428 $2,514 $2,538 $2,653 $2,653
Mucopolysaccharidoses (MPS) $10 $8 $6 $6 $6 $6
Multiple Sclerosis $115 $112 $102 $94 $98 $98
Muscular Dystrophy $75 $76 $78 $77 $80 $80
Myasthenia Gravis $7 $7 $8 $7 $7 $7
Myotonic Dystrophy $10 $10 $9 $9 $10 $10
Nanotechnology 12/ $456 $430 $409 $364 $381 $381
Networking and Information Technology R&D 12/ $532 $521 $612 $729 $764 $764
Neuroblastoma $34 $33 $37 $32 $33 $33
Neurodegenerative $1,671 $1,619 $1,743 $1,662 $1,744 $1,744
Neurofibromatosis $18 $17 $21 $22 $23 $23
Neurosciences $5,618 $5,340 $5,580 $5,742 $6,041 $6,041
Nutrition $1,692 $1,524 $1,555 $1,574 $1,631 $1,631
Obesity $836 $812 $857 $900 $931 $931
Organ Transplantation $150 $140 $142 $148 $154 $154
Orphan Drug $809 $764 $809 $785 $817 $817
Osteoarthritis + + + $76 $79 $79
Osteogenesis Imperfecta $9 $8 $11 $11 $11 $11
Osteoporosis $181 $164 $141 $146 $151 $151
Otitis Media $17 $14 $16 $15 $16 $16
Ovarian Cancer $147 $133 $131 $118 $123 $123
Paget's Disease $1 $0 $0 $1 $1 $1
Pain Conditions - Chronic $396 $402 $402 $391 $406 $406
Pain Research $479 $475 $499 $463 $481 $481
Pancreatic Cancer $127 $125 $123 $174 $181 $181
Parkinson's Disease $154 $135 $139 $146 $152 $152
Patient Safety $845 $858 $1,008 $861 $897 $897
Pediatric $3,612 $3,266 $3,486 $3,632 $3,766 $3,766
Pediatric AIDS 9/ $219 $188 $166 $166 $168 $170
Pediatric Cancer + + $276 $342 $355 $355
Pediatric Research Initiative $379 $258 $343 $512 $522 $522
Pelvic Inflammatory Disease $3 $3 $2 $4 $5 $5
Perinatal - Birth - Preterm (LBW) $217 $198 $206 $223 $230 $230
Perinatal - Neonatal Respiratory Distress Syndrome $38 $33 $52 $31 $32 $32
Perinatal Period - Conditions Originating in Perinatal Period $538 $486 $534 $561 $578 $578
Peripheral Neuropathy 18/ $145 $151 $156 $105 $109 $109
Physical Rehabilitation + + $113 $120 $125 $125
Pick's Disease $2 $3 $4 $2 $3 $3
Pneumonia $115 $113 $107 $112 $117 $117
Pneumonia & Influenza $358 $407 $362 $384 $401 $401
Polycystic Kidney Disease $42 $40 $36 $29 $31 $31
Post-Traumatic Stress Disorder (PTSD) $0 $77 $79 $85 $88 $88
Prescription Drug Abuse $33 $33 $40 $48 $49 $49
Prevention $5,924 $6,686 $6,858 $7,027 $7,300 $7,300
Prostate Cancer $257 $286 $254 $288 $299 $299
Psoriasis $10 $12 $13 $14 $14 $14
Rare Diseases $3,623 $3,456 $3,639 $3,679 $3,832 $3,832
Regenerative Medicine $877 $831 $836 $862 $898 $898
Rehabilitation $449 $446 $494 $514 $537 $537
Rett Syndrome $13 $13 $12 $12 $12 $12
Reye's Syndrome $0 $0 $0 $0 - -
Rheumatoid Arthritis + + + $59 $62 $62
Rural Health $231 $187 $197 $192 $200 $200
Schizophrenia $268 $232 $253 $241 $251 $251
Scleroderma $24 $21 $24 $22 $23 $23
Screening And Brief Intervention For Substance Abuse $31 $25 $30 $35 $36 $36
Septicemia $96 $88 $100 $103 $108 $108
Serious Mental Illness + + $407 $381 $396 $396
Sexual and Gender Minorities (SGM/LGBT*) 10/ + + + $162 $169 $169
Sexually Transmitted Diseases/Herpes $275 $242 $263 $250 $260 $260
Sickle Cell Disease $65 $70 $75 $75 $78 $78
Sleep Research $238 $229 $233 $313 $326 $326
Small Pox $40 $30 $24 $17 $18 $18
Smoking and Health $353 $321 $320 $298 $308 $308
Spina Bifida $12 $10 $10 $10 $10 $10
Spinal Cord Injury $79 $94 $80 $82 $86 $86
Spinal Muscular Atrophy $15 $13 $16 $11 $12 $12
Stem Cell Research $1,374 $1,273 $1,391 $1,429 $1,495 $1,495
Stem Cell Research - Embryonic - Human $146 $146 $166 $180 $191 $191
Stem Cell Research - Embryonic - Non-Human $164 $154 $150 $159 $168 $168
Stem Cell Research - Induced Pluripotent Stem Cell $206 $228 $313 $324 $339 $339
Stem Cell Research - Induced Pluripotent Stem Cell - Human $175 $199 $280 $282 $296 $296
Stem Cell Research - Induced Pluripotent Stem Cell - Non-Human $48 $43 $49 $61 $63 $63
Stem Cell Research - Nonembryonic - Human $504 $431 $443 $445 $465 $465
Stem Cell Research - Nonembryonic - Non-Human $653 $613 $627 $632 $658 $658
Stem Cell Research - Umbilical Cord Blood/ Placenta $47 $40 $34 $35 $37 $37
Stem Cell Research - Umbilical Cord Blood/ Placenta - Human $43 $35 $28 $32 $32 $32
Stem Cell Research - Umbilical Cord Blood/ Placenta - Non-Human $8 $7 $7 $6 $6 $6
Stroke $310 $282 $300 $288 $300 $300
Substance Abuse 13/ $1,634 $1,525 $1,564 $1,549 $1,607 $1,607
Substance Abuse Prevention $41 $65 $69 $67 $69 $69
Sudden Infant Death Syndrome $24 $20 $20 $17 $18 $18
Suicide $44 $37 $39 $46 $48 $48
Suicide Prevention $22 $21 $22 $24 $25 $25
Teenage Pregnancy $18 $17 $16 $14 $15 $15
Temporomandibular Muscle/Joint Disorder (TMJD) $21 $19 $18 $16 $16 $16
Therapeutic Cannabinoid Research + + + $21 $22 $22
Tobacco $355 $322 $321 $300 $310 $310
Topical Microbicides $99 $93 $103 $107 $112 $112
Tourette Syndrome $6 $4 $4 $5 $5 $5
Transmissible Spongiform Encephalopathy (TSE) $39 $35 $33 $36 $37 $37
Transplantation $552 $538 $561 $582 $606 $606
Tuberculosis $218 $240 $279 $272 $278 $278
Tuberculosis Vaccine $21 $26 $31 $23 $24 $24
Tuberous Sclerosis $23 $20 $24 $21 $22 $22
Underage Drinking $80 $75 $83 $74 $77 $77
Underage Drinking – Prevention & Treatment (NIAAA Only) 16/ $62 $62 $59 $52 $54 $54
Urologic Diseases $496 $497 $494 $527 $548 $548
Usher Syndrome + + $19 $16 $17 $17
Uterine Cancer $42 $39 $57 $52 $54 $54
Vaccine Related $1,691 $1,608 $1,573 $1,585 $1,653 $1,653
Vaccine related (AIDS) 9/ $557 $518 $533 $541 $553 $554
Valley Fever + + $3 $11 $11 $11
Vascular Cognitive Impairment/Dementia + + $45 $72 $75 $75
Vector-Borne Diseases $441 $437 $487 $439 $459 $459
Violence Against Women $36 $31 $35 $31 $32 $32
Violence Research $154 $137 $130 $107 $111 $111
Vulvodynia $4 $4 $3 $2 $2 $2
West Nile Virus $29 $40 $48 $40 $42 $42
Women's Health 8/ $3,833 $3,745 $3,935 $3,989 $4,140 $4,140
Youth Violence $77 $70 $59 $47 $48 $48
Youth Violence Prevention $27 $26 $16 $15 $16 $16
[*] The minimum reporting threshold for a specific disease/condition is $500,000. Reporting of $0 does not indicate that no research is being conducted.
[+] Indicates a new category. Funding support data not available prior to the initial year reported.
1/ Name revised in FY 2015 to account for more inclusive definition of research addressing the harms and benefits related to alcohol use.
2/ New categories established pursuant to Section 230, Division G of the Consolidated and Further Continuing Appropriations Act of 2015 as related to reporting of NIH initiatives supporting the National Alzheimer’s Project Act (NAPA) https://aspe.hhs.gov/national-alzheimers-project-act. The new Alzheimer’s Disease Related Dementias (ADRD) category reflects the sum of the three existing RCDC categories: Frontotemporal Dementia (FTD), Lewy Body Dementia and Vascular Cognitive Impairment/Dementia – where duplicates are removed. The new category Alzheimer’s Disease including Alzheimer’s Disease Related Dementias reflects the sum of the two existing RCDC categories: Alzheimer’s Disease and the above new Alzheimer’s Disease Related Dementias (ADRD) – where duplicates are removed.
3/ Reporting for this category does not follow the standard RCDC process. The total amount reported is consistent with reporting requirements for this category to the U.S. Office of Management & Budget (OMB). The project listing does not include non-project or other support costs associated with the annual total for this category. Additional information on this category is available at https://www.niaid.nih.gov/topics/biodefenserelated/pages/default.aspx.
4/ Includes research funded from the Type 1 diabetes appropriation. These are project listings only.
5/ Reporting for this category does not follow the standard RCDC process. Spending for this category is reported consistent with U.S. Office of National Drug Control Policy (ONDCP) requirements. This category includes only projects funded by NIDA. More information on this area is available at https://www.drugabuse.gov/drugs-abuse. FY 2014 actual and FY 2015 estimate reported in RePORT can differ from levels identified in the FY 2016 Drug Control budget submission for those fiscal years where comparable adjustments have been applied.
6/ Reported total for this category encompasses research for anorexia, bulimia nervosa, binge eating disorders, and eating disorders not otherwise specified.
7/ Name revised in FY 2015 and definition refined. Category merges projects identified as Foodborne Illness with relevant projects from the prior “Food Safety” category. Historical data is maintained in separately to assure that information for predecessor categories is not conflated with the merged category.
8/ Reporting for this category does not follow the standard RCDC process. This category assigns project funding according to populations tracked by gender or ethnicity. The databases used to track gender/ethnicity are complex are not currently compatible with the RCDC system.
9/ The total for AIDS research includes both extramural and intramural research (including research management and support, Management Fund, and Service & Supply Fund), buildings and facilities, research training, and program evaluation, as well as research on the many HIV-associated co-infections and co-morbidities, including TB, hepatitis C, and HIV-associated cancers. It also includes all of the basic science underlying this research. Other RCDC categories are not reported this way; thus the total for AIDS-related research is not comparable to spending reported for other RCDC diseases. More information on this area is available at https://www.oar.nih.gov/hivaids/.
10/ This category includes projects that are focused on basic, pre-clinical, clinical, biomedical, health services, behavioral, and social research relevant to sexual and gender minority (SGM) populations. The SGM population – often referred to as LGBT, is asterisked to recognize the diversity in membership as well as sensitivities associated with the variety of descriptive names in use by the medical communities and general public. LGBT research pertains to people whose sexual orientation is not exclusively heterosexual, i.e. lesbian, gay, and bisexual persons. Research projects can likewise focus on individuals whose gender identity differs from the sex originally assigned to them at birth, gender non-conforming or gender variant, or who may not self-identify as LGBT (such as queer, questioning, two-spirit, asexual, etc.). Research also can cover individuals who are born with conditions in which development of chromosomal, gonadal, or anatomic sex is atypical, i.e. people who identify themselves as intersex or with differences/disorders of sex development (DSD). DSD can include, but are not limited to: Y chromosome aneuploidy, congenital adrenal hyperplasia, complete androgen insensitivity, partial androgen insensitivity, gonadal dysgenesis, mixed gonadal dysgenesis, hypospadias, Klinefelter syndrome, Turner syndrome, 5aRD2 deficiency, aromatase defects, MRKH syndrome and gynecomastia.
11/ Reporting for this category does not follow the standard RCDC process. This category uses a non-standard approach involving subject matter expert reviews of manually collected project listings.
12/ The data provided reflects funding amounts reported by the NIH RCDC process for this category. Actual and estimate levels presented on this site supersede estimates detailed in OMB MAX DE application tables that may have been based on preliminary funding support information.
13/ Reporting for this category does not follow the standard RCDC process. This category includes all spending reported under the Drug Abuse category as well as projects categorized under the broader area of Substance Abuse. These are project listings only. More information on this area is available at https://www.drugabuse.gov/drugs-abuse.
14/ Prior to FY 2011, this category's title was "Health Effects of Climate Change". The title was revised to more accurately reflect the content of the research conducted and facilitate reporting spending data in response to requests tracking climate change adaptation.
15/ Name revised in FY 2013 to reflect current scientific terminology.
16/ Reporting for this category does not follow the standard RCDC process. Spending for this category is reported consistent with U.S. Office of National Drug Control Policy (ONDCP) requirements. This category includes only projects funded and administered by NIAAA. This category represents a subset of spending reported under the RCDC Underage Drinking category and involves manual review of the project listing by subject matter experts. More information on this area is available at https://www.niaaa.nih.gov/research/major-initiatives/underage-drinking-research-initiative. The FY 2015 actual or and FY 2016 estimate display in RePORT can differ from levels identified in the FY 2017 Drug Control budget submission for those fiscal years where either comparable adjustments have been applied or historical data was refined.
17/ Name revised in FY 2015 from “Clinical Trials”.
18/ Name revised in FY 2015 from “Neuropathy”.
19/ Estimates of United States disease burden are provided as mortality and prevalence figures for calendar year 2014. Figures for mortality data are drawn from the National Vital Statistics System (NVSS), and indicate the number of deaths in which a particular disease or condition was mentioned on a deceased individual’s death certificate. Prevalence figures are drawn from National Health Interview Survey(NHIS) responses and report the percentage of respondents who indicated that they were affected by a particular health condition. Estimates of mortality and prevalence are not available for all NIH spending categories. Further descriptions of these disease statistics can be found here.
[**] indicates that prevalence was measured in children < 18